ZA884937B - Antipsychotic compositions containing dioxopiperidine derivatives - Google Patents
Antipsychotic compositions containing dioxopiperidine derivativesInfo
- Publication number
- ZA884937B ZA884937B ZA884937A ZA884937A ZA884937B ZA 884937 B ZA884937 B ZA 884937B ZA 884937 A ZA884937 A ZA 884937A ZA 884937 A ZA884937 A ZA 884937A ZA 884937 B ZA884937 B ZA 884937B
- Authority
- ZA
- South Africa
- Prior art keywords
- alkyl
- methyl
- hydrogen
- compositions containing
- alkoxy
- Prior art date
Links
- 230000000561 anti-psychotic effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- CNMOHEDUVVUVPP-UHFFFAOYSA-N piperidine-2,3-dione Chemical class O=C1CCCNC1=O CNMOHEDUVVUVPP-UHFFFAOYSA-N 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- UJFNSGBGJMRZKS-UHFFFAOYSA-N agn-2979 Chemical compound COC1=CC=CC(C2(CCCN(C)C)C(CC(=O)NC2=O)(C)C)=C1 UJFNSGBGJMRZKS-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 201000000980 schizophrenia Diseases 0.000 abstract 1
- 239000000932 sedative agent Substances 0.000 abstract 1
- 230000001624 sedative effect Effects 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB878716337A GB8716337D0 (en) | 1987-07-10 | 1987-07-10 | Antipsychotic compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA884937B true ZA884937B (en) | 1990-03-28 |
Family
ID=10620478
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA884937A ZA884937B (en) | 1987-07-10 | 1988-07-08 | Antipsychotic compositions containing dioxopiperidine derivatives |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4877800A (xx) |
| EP (1) | EP0298738B1 (xx) |
| JP (1) | JPS6463516A (xx) |
| AT (1) | ATE81003T1 (xx) |
| AU (1) | AU606701B2 (xx) |
| CA (1) | CA1328077C (xx) |
| DE (1) | DE3874982T2 (xx) |
| DK (1) | DK170360B1 (xx) |
| GB (2) | GB8716337D0 (xx) |
| IE (1) | IE61536B1 (xx) |
| PT (1) | PT87954B (xx) |
| ZA (1) | ZA884937B (xx) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5177086A (en) * | 1988-11-10 | 1993-01-05 | National Research Development Corporation | Memory-enhancing compositions containing dioxopiperidine derivatives |
| GB8826308D0 (en) * | 1988-11-10 | 1988-12-14 | Nat Res Dev | Memory-enhancing compositions containing dioxopiperidine derivatives |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1455687A (en) * | 1972-12-28 | 1976-11-17 | Aspro Nicholas Ltd | Pharmacologically active 3-phenyl-3-aminoalkyl-2,6-dioxo-hydro genated pyridines |
| GB2181346B (en) * | 1985-09-11 | 1989-10-04 | Nat Res Dev | Pharmaceutical compositions and medical uses of dioxopiperidine derivatives |
| US4705796A (en) * | 1986-08-25 | 1987-11-10 | Stereochemical Genetics, Inc. | Use of 3-N-phenylacetylamino-2,6-piperidinedione for treatment of neuropsychiatric disorders |
| GB2196251B (en) * | 1986-09-08 | 1990-07-04 | Nat Res Dev | Anxiolytic compositions containing dioxopiperidine derivatives |
-
1987
- 1987-07-10 GB GB878716337A patent/GB8716337D0/en active Pending
-
1988
- 1988-07-07 AT AT88306207T patent/ATE81003T1/de not_active IP Right Cessation
- 1988-07-07 GB GB8816213A patent/GB2206490B/en not_active Expired - Lifetime
- 1988-07-07 EP EP88306207A patent/EP0298738B1/en not_active Expired - Lifetime
- 1988-07-07 DE DE8888306207T patent/DE3874982T2/de not_active Expired - Fee Related
- 1988-07-08 AU AU18861/88A patent/AU606701B2/en not_active Ceased
- 1988-07-08 ZA ZA884937A patent/ZA884937B/xx unknown
- 1988-07-08 IE IE208688A patent/IE61536B1/en not_active IP Right Cessation
- 1988-07-08 PT PT87954A patent/PT87954B/pt not_active IP Right Cessation
- 1988-07-08 DK DK382588A patent/DK170360B1/da not_active IP Right Cessation
- 1988-07-11 US US07/217,450 patent/US4877800A/en not_active Expired - Fee Related
- 1988-07-11 CA CA000571649A patent/CA1328077C/en not_active Expired - Fee Related
- 1988-07-11 JP JP63173620A patent/JPS6463516A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0298738A3 (en) | 1989-08-09 |
| DK170360B1 (da) | 1995-08-14 |
| IE61536B1 (en) | 1994-11-16 |
| GB8816213D0 (en) | 1988-08-10 |
| PT87954A (pt) | 1989-06-30 |
| AU606701B2 (en) | 1991-02-14 |
| PT87954B (pt) | 1995-03-01 |
| JPS6463516A (en) | 1989-03-09 |
| CA1328077C (en) | 1994-03-29 |
| DE3874982T2 (de) | 1993-04-01 |
| GB2206490B (en) | 1991-09-18 |
| IE882086L (en) | 1989-01-10 |
| DK382588D0 (da) | 1988-07-08 |
| AU1886188A (en) | 1989-01-27 |
| EP0298738A2 (en) | 1989-01-11 |
| GB2206490A (en) | 1989-01-11 |
| DE3874982D1 (de) | 1992-11-05 |
| DK382588A (da) | 1989-01-11 |
| US4877800A (en) | 1989-10-31 |
| EP0298738B1 (en) | 1992-09-30 |
| ATE81003T1 (de) | 1992-10-15 |
| GB8716337D0 (en) | 1987-08-19 |
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