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ZA844782B - Novel beta-carbolines,a process for the preparation thereof and use as medicinal agents(h) - Google Patents

Novel beta-carbolines,a process for the preparation thereof and use as medicinal agents(h)

Info

Publication number
ZA844782B
ZA844782B ZA844782A ZA844782A ZA844782B ZA 844782 B ZA844782 B ZA 844782B ZA 844782 A ZA844782 A ZA 844782A ZA 844782 A ZA844782 A ZA 844782A ZA 844782 B ZA844782 B ZA 844782B
Authority
ZA
South Africa
Prior art keywords
alkyl
hydrogen
image
carbolines
preparation
Prior art date
Application number
ZA844782A
Other languages
English (en)
Inventor
Dieter Seidelmann
Ralph Schmiechen
Andreas Huth
Dieter Rahtz
Claus Thyco Braestrup
Mogens Engelstoft
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of ZA844782B publication Critical patent/ZA844782B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Treating Waste Gases (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
ZA844782A 1983-06-23 1984-06-22 Novel beta-carbolines,a process for the preparation thereof and use as medicinal agents(h) ZA844782B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833322894 DE3322894A1 (de) 1983-06-23 1983-06-23 Neue (beta)-carboline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel (h)

Publications (1)

Publication Number Publication Date
ZA844782B true ZA844782B (en) 1985-02-27

Family

ID=6202361

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA844782A ZA844782B (en) 1983-06-23 1984-06-22 Novel beta-carbolines,a process for the preparation thereof and use as medicinal agents(h)

Country Status (17)

Country Link
US (1) US4600715A (xx)
EP (1) EP0130141B1 (xx)
JP (1) JPS6013791A (xx)
AT (1) ATE56449T1 (xx)
AU (1) AU576199B2 (xx)
CA (1) CA1240324A (xx)
DE (2) DE3322894A1 (xx)
DK (1) DK169968B1 (xx)
ES (1) ES8504191A1 (xx)
FI (1) FI79110C (xx)
GR (1) GR82123B (xx)
HU (1) HU192052B (xx)
IE (1) IE57624B1 (xx)
IL (1) IL72166A (xx)
NO (1) NO160783C (xx)
SU (1) SU1376940A3 (xx)
ZA (1) ZA844782B (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ194747A (en) * 1979-08-29 1988-11-29 Schering Ag 9h-pyrido(3,4-b)indol-3-ylcarboxylic acid derivatives
DE3335323A1 (de) * 1983-09-27 1985-04-04 Schering AG, 1000 Berlin und 4709 Bergkamen Substituierte ss-carboline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3545776A1 (de) * 1985-12-20 1987-06-25 Schering Ag 5-aminoalkyl-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel
US4952584A (en) * 1986-01-11 1990-08-28 Beecham Group P.L.C. 9H-pyrido[2,B-8]indole-3-carboxylic acid ester compounds having useful pharmaceutical activity
US6589954B1 (en) * 1998-05-22 2003-07-08 Scios, Inc. Compounds and methods to treat cardiac failure and other disorders
US6448257B1 (en) * 1998-05-22 2002-09-10 Scios, Inc. Compounds and methods to treat cardiac failure and other disorders
IL146309A (en) * 1999-05-21 2008-03-20 Scios Inc Derivatives of the indole type and pharmaceutical preparations containing them as inhibitors of kinase p38
US20040253891A1 (en) * 2000-09-12 2004-12-16 Schierenbeck Alan W. Composite structure for protective garment
US20050101623A1 (en) * 2003-07-23 2005-05-12 Pharmacia Corporation Beta-carboline compounds and analogues thereof as mitogen-activated protein kinase-activated protein kinase-2 inhibitors
CN110240597A (zh) * 2018-04-04 2019-09-17 宁波大学 一种酰胺衍生化的β-咔啉及其制备方法
CN108191863A (zh) * 2018-04-04 2018-06-22 宁波大学 一种羧酸衍生化的β-咔啉及其制备方法
US11939330B1 (en) 2023-08-25 2024-03-26 King Faisal University Pyrido[3,4-b]indole-6-carboxylic acid compounds as CK2 inhibitors

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5643283A (en) * 1979-08-29 1981-04-21 Schering Ag Betaacarbolinee33carboxylic acid derivative* its manufacture and psychotic medicine containing it
NZ194747A (en) * 1979-08-29 1988-11-29 Schering Ag 9h-pyrido(3,4-b)indol-3-ylcarboxylic acid derivatives
DE3023567A1 (de) * 1980-06-20 1982-01-21 Schering Ag, 1000 Berlin Und 4619 Bergkamen Substituierte (beta) -carbolin-3-carbonsaeurederivate
DE3136857A1 (de) * 1981-09-14 1983-03-31 Schering Ag, 1000 Berlin Und 4619 Bergkamen Substituierte (beta)-carbolin-3-carbonsaeurealkylester, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
JPS57123180A (en) * 1980-12-17 1982-07-31 Schering Ag 3-substituted beta-carboline, manufacture and psychotropic drug containing same
DE3048318A1 (de) * 1980-12-17 1982-07-22 Schering Ag, 1000 Berlin Und 4619 Bergkamen 4-alkoxyalkyl substituierte (beta)-carbolin-3-carbonsaeurederivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3240513A1 (de) * 1982-10-29 1984-05-03 Schering AG, 1000 Berlin und 4709 Bergkamen Indolderivate, verfahren zu ihrer herstellung und deren verwendung zur weiterverarbeitung
DE3240511A1 (de) * 1982-10-29 1984-05-03 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur herstellung von ss-carbolinderivaten

Also Published As

Publication number Publication date
FI842500A0 (fi) 1984-06-20
DE3483180D1 (de) 1990-10-18
IE841574L (en) 1984-12-23
NO160783C (no) 1989-05-31
CA1240324A (en) 1988-08-09
HUT34480A (en) 1985-03-28
IL72166A0 (en) 1984-10-31
JPS6013791A (ja) 1985-01-24
DK169968B1 (da) 1995-04-18
EP0130141A2 (de) 1985-01-02
EP0130141A3 (en) 1985-10-16
ES533378A0 (es) 1985-04-16
HU192052B (en) 1987-05-28
US4600715A (en) 1986-07-15
FI79110C (fi) 1989-11-10
ES8504191A1 (es) 1985-04-16
ATE56449T1 (de) 1990-09-15
AU2955384A (en) 1985-01-03
DK304584D0 (da) 1984-06-21
GR82123B (xx) 1984-12-13
IE57624B1 (en) 1993-02-10
DK304584A (da) 1984-12-24
EP0130141B1 (de) 1990-09-12
DE3322894A1 (de) 1985-01-03
SU1376940A3 (ru) 1988-02-23
AU576199B2 (en) 1988-08-18
JPH0585553B2 (xx) 1993-12-07
IL72166A (en) 1988-06-30
FI842500A (fi) 1984-12-24
NO842482L (no) 1984-12-27
NO160783B (no) 1989-02-20
FI79110B (fi) 1989-07-31

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