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ZA825291B - Phenylalkyloxiranecarboxylic acids,a process for their preparation,their use,and medicaments containing them - Google Patents

Phenylalkyloxiranecarboxylic acids,a process for their preparation,their use,and medicaments containing them

Info

Publication number
ZA825291B
ZA825291B ZA825291A ZA825291A ZA825291B ZA 825291 B ZA825291 B ZA 825291B ZA 825291 A ZA825291 A ZA 825291A ZA 825291 A ZA825291 A ZA 825291A ZA 825291 B ZA825291 B ZA 825291B
Authority
ZA
South Africa
Prior art keywords
group
preparation
denotes
lower alkyl
acids
Prior art date
Application number
ZA825291A
Inventor
Bernhard Kohl
Klaus Eistetter
Hermann Amschler
Gerhard Ludwig
Horst Wolf
Original Assignee
Byk Gulden Lomberg Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chem Fab filed Critical Byk Gulden Lomberg Chem Fab
Publication of ZA825291B publication Critical patent/ZA825291B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Epoxy Compounds (AREA)
  • Pyrane Compounds (AREA)

Abstract

Phenylalkyloxirane carboxylic acids of the general formula I <IMAGE> wherein R<1> denotes a hydrogen atom, a halogen atom, a lower alkyl group, a lower alkoxy group or a trifluoromethyl group, R<2> has one of the meanings of R<1>, A denotes a single bond, a -CH(R<6>)-CH(R<7>)-group, a CH(R<6>)-CH(R<7>)-CH(R<8>)-group or a -CH(R<6>)-CH(R<7>)-CH(R<8>)-CH(R<9>)-group, R<5> denotes a hydrogen atom or a lower alkyl group and one of the substituents R<3>, R<4>, R<6>, R<7>, R<8> or R<9> represents a lower alkyl group and the others denote hydrogen atoms, and the salts of the carboxylic acids are new compounds having a hypoglycaemic action. A process for their preparation and a new process for the preparation of the intermediate products is described.
ZA825291A 1981-07-24 1982-07-23 Phenylalkyloxiranecarboxylic acids,a process for their preparation,their use,and medicaments containing them ZA825291B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH483881 1981-07-24

Publications (1)

Publication Number Publication Date
ZA825291B true ZA825291B (en) 1983-05-25

Family

ID=4283438

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA825291A ZA825291B (en) 1981-07-24 1982-07-23 Phenylalkyloxiranecarboxylic acids,a process for their preparation,their use,and medicaments containing them

Country Status (11)

Country Link
EP (1) EP0071175B1 (en)
JP (1) JPS58501124A (en)
AT (1) ATE18556T1 (en)
DE (1) DE3269811D1 (en)
DK (1) DK133083A (en)
ES (1) ES8307780A1 (en)
GR (1) GR76871B (en)
IL (1) IL66365A0 (en)
PT (1) PT75311B (en)
WO (1) WO1983000334A1 (en)
ZA (1) ZA825291B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1259827A (en) * 1984-07-17 1989-09-26 Mitsumasa Kurosawa Cold-rolled steel sheets and a method of manufacturing the same
WO1987000751A2 (en) * 1985-08-02 1987-02-12 Byk Gulden Lomberg Chemische Fabrik Gmbh Use of oxirancarboxylic acids for the treatment of hyperlipemia
EP0283168A3 (en) * 1987-03-16 1989-06-14 American Home Products Corporation Fluorooxirane carboxylates
DE19705718A1 (en) 1997-02-14 1998-08-20 Horst P O Dr Wolf New oxirane carboxylic acids to treat type 2 diabetes and other insulin resistant conditions
CN111613407B (en) * 2020-06-03 2022-05-03 福建省长汀金龙稀土有限公司 R-T-B series permanent magnet material, raw material composition, preparation method and application thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0025192B1 (en) * 1979-09-07 1983-05-11 Byk Gulden Lomberg Chemische Fabrik GmbH Substituted oxirane carboxylic acids, process for their preparation, their use and medicines containing them

Also Published As

Publication number Publication date
PT75311A (en) 1982-08-01
EP0071175A3 (en) 1983-04-13
ES514235A0 (en) 1983-08-01
IL66365A0 (en) 1982-11-30
ES8307780A1 (en) 1983-08-01
PT75311B (en) 1985-01-11
EP0071175A2 (en) 1983-02-09
JPS58501124A (en) 1983-07-14
DK133083D0 (en) 1983-03-23
ATE18556T1 (en) 1986-03-15
DK133083A (en) 1983-03-23
GR76871B (en) 1984-09-04
EP0071175B1 (en) 1986-03-12
DE3269811D1 (en) 1986-04-17
WO1983000334A1 (en) 1983-02-03

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