ZA803679B - 5-(4-pyridinyl)-2(lh) pyridinones, useful as cardiotonic agents, and their preparation - Google Patents
5-(4-pyridinyl)-2(lh) pyridinones, useful as cardiotonic agents, and their preparationInfo
- Publication number
- ZA803679B ZA803679B ZA00803679A ZA803679A ZA803679B ZA 803679 B ZA803679 B ZA 803679B ZA 00803679 A ZA00803679 A ZA 00803679A ZA 803679 A ZA803679 A ZA 803679A ZA 803679 B ZA803679 B ZA 803679B
- Authority
- ZA
- South Africa
- Prior art keywords
- pyridinones
- pyridinyl
- useful
- preparation
- cardiotonic agents
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/69—Two or more oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/073,885 US4225601A (en) | 1979-09-10 | 1979-09-10 | 3-Hydroxy or hydroxymethyl-5-(4-pyridinyl)2(1H)-pyridinones, useful as cardiotonic agents and their preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA803679B true ZA803679B (en) | 1981-06-24 |
Family
ID=22116385
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA00803679A ZA803679B (en) | 1979-09-10 | 1980-06-20 | 5-(4-pyridinyl)-2(lh) pyridinones, useful as cardiotonic agents, and their preparation |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4225601A (da) |
| JP (1) | JPS5668670A (da) |
| KR (1) | KR830003470A (da) |
| AR (1) | AR223716A1 (da) |
| AU (1) | AU6003080A (da) |
| BE (1) | BE884329A (da) |
| DE (1) | DE3027901A1 (da) |
| DK (1) | DK314180A (da) |
| ES (1) | ES8106514A1 (da) |
| FI (1) | FI802298A (da) |
| FR (1) | FR2465722A1 (da) |
| GB (1) | GB2058751A (da) |
| IL (1) | IL60360A0 (da) |
| IT (1) | IT1132192B (da) |
| LU (1) | LU82650A1 (da) |
| NL (1) | NL8004126A (da) |
| NO (1) | NO802138L (da) |
| NZ (1) | NZ194106A (da) |
| PT (1) | PT71427A (da) |
| SE (1) | SE8004934L (da) |
| ZA (1) | ZA803679B (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4361569A (en) * | 1981-08-26 | 1982-11-30 | Sterling Drug Inc. | 3-(Hydroxy or hydroxymethyl)-6-methyl-5-(4-pyridinyl)-2(1H)-pyridinone and cardiotonic use thereof |
| US4432979A (en) * | 1981-10-26 | 1984-02-21 | William H. Rorer, Inc. | Pyridone compounds |
| US4463008A (en) * | 1982-11-10 | 1984-07-31 | Sterling Drug Inc. | 2-Alkoxy-5-(pyridinyl)pyridines and cardiotonic use thereof |
| US6068581A (en) * | 1998-04-29 | 2000-05-30 | Timm Medical Technologies, Inc. | Method and apparatus for testing and exercising pelvic muscles |
| EP2542077A4 (en) * | 2010-03-04 | 2013-08-21 | Merck Sharp & Dohme | HEMMER OF CATECHOL-O-METHYL-TRANSFERASE AND ITS USE IN THE TREATMENT OF PSYCHOTIC DISORDER |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4072746A (en) * | 1975-10-14 | 1978-02-07 | Sterling Drug Inc. | 3-Amino-5-(pyridinyl)-2(1H)-pyridinones |
-
1979
- 1979-09-10 US US06/073,885 patent/US4225601A/en not_active Expired - Lifetime
-
1980
- 1980-06-19 IL IL60360A patent/IL60360A0/xx unknown
- 1980-06-20 PT PT71427A patent/PT71427A/pt unknown
- 1980-06-20 ZA ZA00803679A patent/ZA803679B/xx unknown
- 1980-06-20 NZ NZ194106A patent/NZ194106A/xx unknown
- 1980-06-24 GB GB8020570A patent/GB2058751A/en not_active Withdrawn
- 1980-07-02 AU AU60030/80A patent/AU6003080A/en not_active Abandoned
- 1980-07-03 SE SE8004934A patent/SE8004934L/xx not_active Application Discontinuation
- 1980-07-10 KR KR1019800002751A patent/KR830003470A/ko unknown
- 1980-07-14 IT IT23422/80A patent/IT1132192B/it active
- 1980-07-16 NO NO802138A patent/NO802138L/no unknown
- 1980-07-16 FR FR8015702A patent/FR2465722A1/fr not_active Withdrawn
- 1980-07-16 BE BE1/9898A patent/BE884329A/fr unknown
- 1980-07-17 NL NL8004126A patent/NL8004126A/nl not_active Application Discontinuation
- 1980-07-21 FI FI802298A patent/FI802298A/fi not_active Application Discontinuation
- 1980-07-22 ES ES493583A patent/ES8106514A1/es not_active Expired
- 1980-07-22 DK DK314180A patent/DK314180A/da unknown
- 1980-07-23 DE DE19803027901 patent/DE3027901A1/de not_active Withdrawn
- 1980-07-23 AR AR281876A patent/AR223716A1/es active
- 1980-07-23 LU LU82650A patent/LU82650A1/fr unknown
- 1980-08-20 JP JP11463280A patent/JPS5668670A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR830003470A (ko) | 1983-06-20 |
| DE3027901A1 (de) | 1981-03-26 |
| AU6003080A (en) | 1981-03-19 |
| JPS5668670A (en) | 1981-06-09 |
| DK314180A (da) | 1981-03-11 |
| GB2058751A (en) | 1981-04-15 |
| NL8004126A (nl) | 1981-03-12 |
| ES493583A0 (es) | 1981-07-01 |
| IT8023422A0 (it) | 1980-07-14 |
| LU82650A1 (fr) | 1981-03-24 |
| NO802138L (no) | 1981-03-11 |
| NZ194106A (en) | 1982-03-30 |
| IT1132192B (it) | 1986-06-25 |
| ES8106514A1 (es) | 1981-07-01 |
| BE884329A (fr) | 1981-01-16 |
| SE8004934L (sv) | 1981-03-11 |
| FR2465722A1 (fr) | 1981-03-27 |
| FI802298A (fi) | 1981-03-11 |
| PT71427A (en) | 1980-07-01 |
| AR223716A1 (es) | 1981-09-15 |
| IL60360A0 (en) | 1980-09-16 |
| US4225601A (en) | 1980-09-30 |
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