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ZA201408064B - Prodrugs of anti-platelet agents - Google Patents

Prodrugs of anti-platelet agents

Info

Publication number
ZA201408064B
ZA201408064B ZA2014/08064A ZA201408064A ZA201408064B ZA 201408064 B ZA201408064 B ZA 201408064B ZA 2014/08064 A ZA2014/08064 A ZA 2014/08064A ZA 201408064 A ZA201408064 A ZA 201408064A ZA 201408064 B ZA201408064 B ZA 201408064B
Authority
ZA
South Africa
Prior art keywords
prodrugs
platelet agents
platelet
agents
Prior art date
Application number
ZA2014/08064A
Inventor
Mahesh Kandula
Original Assignee
Cellix Bio Private Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cellix Bio Private Ltd filed Critical Cellix Bio Private Ltd
Publication of ZA201408064B publication Critical patent/ZA201408064B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
ZA2014/08064A 2012-05-07 2014-11-04 Prodrugs of anti-platelet agents ZA201408064B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1781CH2012 2012-05-07
PCT/IB2013/052328 WO2013168024A1 (en) 2012-05-07 2013-03-24 Prodrugs of anti-platelet agents

Publications (1)

Publication Number Publication Date
ZA201408064B true ZA201408064B (en) 2016-04-28

Family

ID=54193687

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2014/08064A ZA201408064B (en) 2012-05-07 2014-11-04 Prodrugs of anti-platelet agents

Country Status (8)

Country Link
EP (1) EP2847197A4 (en)
JP (1) JP2015519334A (en)
CN (1) CN104379589A (en)
AU (1) AU2013257745A1 (en)
CA (1) CA2873094A1 (en)
SG (1) SG11201407307YA (en)
WO (1) WO2013168024A1 (en)
ZA (1) ZA201408064B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014006529A2 (en) * 2012-07-03 2014-01-09 Mahesh Kandula Compositions and methods for the treatment of moderate to severe pain
CN114507157B (en) * 2020-11-17 2023-03-24 沧州维智达美制药有限公司 Method for preparing bromoacetonitrile by using chloroacetonitrile
CN119019320B (en) * 2024-10-29 2025-03-11 上海柯君医药科技有限公司 Preparation method of piperidine compound with antiplatelet activity

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6858734B2 (en) * 2003-04-23 2005-02-22 Rhodia Pharma Solutions Inc. Preparation of (S)-Clopidogrel and related compounds
NZ545570A (en) * 2003-07-29 2012-07-27 Signature R & D Holdings Llc Amino acid prodrugs
JPWO2006126676A1 (en) * 2005-05-27 2008-12-25 第一三共株式会社 Cyclic amine derivatives having substituted alkyl groups
KR100990949B1 (en) * 2008-06-09 2010-10-29 엔자이텍 주식회사 Method for preparing clopidogrel and its derivatives
CN102002053A (en) * 2009-09-02 2011-04-06 陕西合成药业有限公司 Tetrahydro thienopyridine derivative for treating
CN102336767A (en) * 2011-07-11 2012-02-01 华东理工大学 Method for preparing high-purity chiral alpha-substituted-6,7-thiaindan[3,2-c]pyridine derivative
WO2013024376A1 (en) * 2011-08-16 2013-02-21 Mahesh Kandula Compositions and methods for the treatment of atherothrombosis
US9525998B2 (en) * 2012-01-06 2016-12-20 Qualcomm Incorporated Wireless display with multiscreen service
CN113225172B (en) * 2012-01-27 2024-05-24 交互数字专利控股公司 Method performed by a WTRU for ePDCCH
US9738631B2 (en) * 2012-05-07 2017-08-22 Cellix Bio Private Limited Compositions and methods for the treatment of neurological disorders
JP2015533114A (en) * 2012-05-08 2015-11-19 セリックスビオ プライヴェート リミテッド Compositions and methods for the treatment of neurological disorders
AU2013257708A1 (en) * 2012-05-08 2014-12-04 Cellixbio Private Limited Compositions and methods for the treatment of diabetes
SG11201407309XA (en) * 2012-05-08 2014-12-30 Cellix Bio Private Ltd Compositions and methods for the treatment of epilepsy
CA2872978A1 (en) * 2012-05-08 2013-11-14 Cellixbio Private Limited Compositions and methods for suppression of carbonic anhydrase activity
WO2014006529A2 (en) * 2012-07-03 2014-01-09 Mahesh Kandula Compositions and methods for the treatment of moderate to severe pain

Also Published As

Publication number Publication date
SG11201407307YA (en) 2014-12-30
EP2847197A1 (en) 2015-03-18
CN104379589A (en) 2015-02-25
JP2015519334A (en) 2015-07-09
CA2873094A1 (en) 2013-11-14
AU2013257745A1 (en) 2014-11-27
EP2847197A4 (en) 2015-11-04
WO2013168024A1 (en) 2013-11-14

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