ZA201008592B - Humanization of rabbit antibodies using a universal antibody framework - Google Patents
Humanization of rabbit antibodies using a universal antibody frameworkInfo
- Publication number
- ZA201008592B ZA201008592B ZA2010/08592A ZA201008592A ZA201008592B ZA 201008592 B ZA201008592 B ZA 201008592B ZA 2010/08592 A ZA2010/08592 A ZA 2010/08592A ZA 201008592 A ZA201008592 A ZA 201008592A ZA 201008592 B ZA201008592 B ZA 201008592B
- Authority
- ZA
- South Africa
- Prior art keywords
- humanization
- antibody framework
- rabbit antibodies
- universal antibody
- universal
- Prior art date
Links
- 241000283973 Oryctolagus cuniculus Species 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7569708P | 2008-06-25 | 2008-06-25 | |
| US7569208P | 2008-06-25 | 2008-06-25 | |
| US15504109P | 2009-02-24 | 2009-02-24 | |
| US15510509P | 2009-02-24 | 2009-02-24 | |
| CH8322009 | 2009-06-02 | ||
| PCT/CH2009/000222 WO2009155726A2 (en) | 2008-06-25 | 2009-06-25 | Humanization of rabbit antibodies using a universal antibody framework |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA201008592B true ZA201008592B (en) | 2014-02-26 |
Family
ID=53532693
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2010/08592A ZA201008592B (en) | 2008-06-25 | 2010-11-30 | Humanization of rabbit antibodies using a universal antibody framework |
| ZA2013/08755A ZA201308755B (en) | 2008-06-25 | 2013-11-21 | Humanization of rabbit antibodies using a universal antibody framework |
| ZA2015/03267A ZA201503267B (en) | 2008-06-25 | 2015-05-11 | Humanization of rabbit antibodies using a universal antibody framework |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2013/08755A ZA201308755B (en) | 2008-06-25 | 2013-11-21 | Humanization of rabbit antibodies using a universal antibody framework |
| ZA2015/03267A ZA201503267B (en) | 2008-06-25 | 2015-05-11 | Humanization of rabbit antibodies using a universal antibody framework |
Country Status (9)
| Country | Link |
|---|---|
| JP (5) | JP2015120746A (ja) |
| KR (2) | KR102284435B1 (ja) |
| CL (1) | CL2010001539A1 (ja) |
| ES (1) | ES2771150T3 (ja) |
| HU (1) | HUE047678T2 (ja) |
| PH (2) | PH12013502219A1 (ja) |
| PT (2) | PT2752428T (ja) |
| RU (2) | RU2696202C1 (ja) |
| ZA (3) | ZA201008592B (ja) |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0938506B1 (en) * | 1996-07-16 | 2003-11-05 | Plückthun, Andreas, Prof. Dr. | Immunoglobulin superfamily domains and fragments with increased solubility |
| EP2044839A3 (en) * | 2000-08-03 | 2009-07-01 | Therapeutic Human Polyclonals, Inc. | Production of humanized antibodies in transgenic animals |
| AU2002303496A2 (en) * | 2001-04-25 | 2002-11-05 | Weigel, Janet A | Methods of using a hyaluronan receptor |
| AU2003217912A1 (en) * | 2002-03-01 | 2003-09-16 | Xencor | Antibody optimization |
| PT2332989E (pt) * | 2002-05-22 | 2015-08-05 | Esbatech Alcon Biomed Res Unit | Estruturas de imunoglobulina que demonstram estabilidade aumentada no ambiente intracelular e métodos de identificação das mesmas |
| WO2004016740A2 (en) * | 2002-08-15 | 2004-02-26 | Epitomics, Inc. | Humanized rabbit antibodies |
| JP2007520991A (ja) * | 2003-08-07 | 2007-08-02 | エピトミクス インコーポレーティッド | ウサギ単クローン抗体をヒト型化する方法 |
| US20050042664A1 (en) * | 2003-08-22 | 2005-02-24 | Medimmune, Inc. | Humanization of antibodies |
| US7431927B2 (en) * | 2005-03-24 | 2008-10-07 | Epitomics, Inc. | TNFα-neutralizing antibodies |
| DK2390267T3 (da) * | 2005-06-07 | 2013-08-26 | Esbatech A Novartis Co Llc | Stabile og opløselige antistoffer, der hæmmer TNF(alfa) |
| PT2135881E (pt) * | 2005-06-20 | 2011-12-21 | Genentech Inc | Anticorpos que se ligam ao antigénio tat10772 associado a tumor para o diagnóstico e tratamento de tumor |
| GB0520436D0 (en) * | 2005-10-07 | 2005-11-16 | Photobiotics Ltd | Biological materials and uses thereof |
| WO2008004834A1 (en) * | 2006-07-06 | 2008-01-10 | Isu Abxis Co., Ltd | Humanized monoclonal antibody highly binding to epidermal growth factor receptor, egf receptor |
| SG196697A1 (en) * | 2007-03-22 | 2014-02-13 | Biogen Idec Inc | Binding proteins, including antibodies, antibody derivatives and antibody fragments, that specifically bind cd154 and uses thereof |
-
2009
- 2009-06-25 KR KR1020197022505A patent/KR102284435B1/ko active Active
- 2009-06-25 PT PT141626648T patent/PT2752428T/pt unknown
- 2009-06-25 PT PT97686950T patent/PT2307458T/pt unknown
- 2009-06-25 KR KR1020217023841A patent/KR20210097819A/ko not_active Withdrawn
- 2009-06-25 HU HUE14162664A patent/HUE047678T2/hu unknown
- 2009-06-25 ES ES14162664T patent/ES2771150T3/es active Active
-
2010
- 2010-11-30 ZA ZA2010/08592A patent/ZA201008592B/en unknown
- 2010-12-23 CL CL2010001539A patent/CL2010001539A1/es unknown
-
2013
- 2013-10-25 PH PH12013502219A patent/PH12013502219A1/en unknown
- 2013-11-21 ZA ZA2013/08755A patent/ZA201308755B/en unknown
-
2015
- 2015-03-18 JP JP2015054497A patent/JP2015120746A/ja not_active Withdrawn
- 2015-05-11 ZA ZA2015/03267A patent/ZA201503267B/en unknown
-
2016
- 2016-04-27 JP JP2016088845A patent/JP2016135815A/ja active Pending
-
2017
- 2017-07-31 JP JP2017148091A patent/JP6568557B2/ja active Active
-
2018
- 2018-03-19 RU RU2018109506A patent/RU2696202C1/ru active
- 2018-08-13 PH PH12018501715A patent/PH12018501715A1/en unknown
-
2019
- 2019-02-01 JP JP2019016882A patent/JP6903083B2/ja active Active
- 2019-06-21 RU RU2019119412A patent/RU2019119412A/ru unknown
-
2020
- 2020-04-30 JP JP2020080224A patent/JP2020114260A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JP2016135815A (ja) | 2016-07-28 |
| KR20190091578A (ko) | 2019-08-06 |
| KR102284435B1 (ko) | 2021-08-02 |
| JP6568557B2 (ja) | 2019-08-28 |
| JP6903083B2 (ja) | 2021-07-14 |
| RU2019119412A (ru) | 2020-12-21 |
| JP2015120746A (ja) | 2015-07-02 |
| PH12013502219A1 (en) | 2016-01-25 |
| HUE047678T2 (hu) | 2020-05-28 |
| ES2771150T3 (es) | 2020-07-06 |
| JP2019065050A (ja) | 2019-04-25 |
| JP2017190352A (ja) | 2017-10-19 |
| PH12018501715A1 (en) | 2019-08-19 |
| JP2020114260A (ja) | 2020-07-30 |
| ZA201308755B (en) | 2015-08-26 |
| ZA201503267B (en) | 2016-07-27 |
| PT2307458T (pt) | 2018-07-18 |
| CL2010001539A1 (es) | 2012-02-03 |
| RU2696202C1 (ru) | 2019-07-31 |
| KR20210097819A (ko) | 2021-08-09 |
| PT2752428T (pt) | 2020-02-14 |
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