ZA201002095B - Solid dispersion product of n-aryl urea-based drugs - Google Patents
Solid dispersion product of n-aryl urea-based drugsInfo
- Publication number
- ZA201002095B ZA201002095B ZA2010/02095A ZA201002095A ZA201002095B ZA 201002095 B ZA201002095 B ZA 201002095B ZA 2010/02095 A ZA2010/02095 A ZA 2010/02095A ZA 201002095 A ZA201002095 A ZA 201002095A ZA 201002095 B ZA201002095 B ZA 201002095B
- Authority
- ZA
- South Africa
- Prior art keywords
- solid dispersion
- based drugs
- dispersion product
- aryl urea
- urea
- Prior art date
Links
- 239000004202 carbamide Substances 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 239000007962 solid dispersion Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99961807P | 2007-10-19 | 2007-10-19 | |
| PCT/EP2008/064076 WO2009050291A2 (en) | 2007-10-19 | 2008-10-17 | Solid dispersion product of n-aryl urea-based drugs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA201002095B true ZA201002095B (en) | 2011-11-30 |
Family
ID=40089463
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2010/02095A ZA201002095B (en) | 2007-10-19 | 2010-03-24 | Solid dispersion product of n-aryl urea-based drugs |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP2197425A2 (es) |
| JP (1) | JP2011500649A (es) |
| KR (1) | KR20100087170A (es) |
| CN (1) | CN101827584A (es) |
| AU (1) | AU2008313622A1 (es) |
| BR (1) | BRPI0818340A2 (es) |
| CA (1) | CA2699301A1 (es) |
| CO (1) | CO6270206A2 (es) |
| CR (1) | CR11442A (es) |
| DO (1) | DOP2010000117A (es) |
| EC (1) | ECSP10010183A (es) |
| GT (1) | GT201000102A (es) |
| MX (1) | MX2010004291A (es) |
| PA (1) | PA8800101A1 (es) |
| RU (1) | RU2010119929A (es) |
| UA (1) | UA100865C2 (es) |
| WO (1) | WO2009050291A2 (es) |
| ZA (1) | ZA201002095B (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090203709A1 (en) * | 2008-02-07 | 2009-08-13 | Abbott Laboratories | Pharmaceutical Dosage Form For Oral Administration Of Tyrosine Kinase Inhibitor |
| AR077975A1 (es) | 2009-08-28 | 2011-10-05 | Irm Llc | Derivados de pirazol pirimidina y composiciones como inhibidores de cinasa de proteina |
| WO2011156361A2 (en) * | 2010-06-09 | 2011-12-15 | Abbott Laboratories | Solid dispersions containing kinase inhibitors |
| AU2012335663B2 (en) | 2011-11-11 | 2015-12-24 | Array Biopharma Inc. | Method of treating a proliferative disease |
| AR088936A1 (es) | 2011-11-23 | 2014-07-16 | Novartis Ag | Formulaciones farmaceuticas |
| WO2014003677A1 (en) * | 2012-06-28 | 2014-01-03 | Xspray Microparticles Ab | Pharmaceutical compositions comprising solid dispersion particles containing tadalafil |
| WO2014003678A1 (en) * | 2012-06-28 | 2014-01-03 | Xspray Microparticles Ab | Pharmaceutical compositions comprising ambrisentan and solid dispersion particles containing tadalafil |
| JP6796083B2 (ja) | 2015-06-09 | 2020-12-02 | カプスゲル・ベルギウム・ナムローゼ・フェンノートシャップＣａｐｓｕｇｅｌ Ｂｅｌｇｉｕｍ ＮＶ | カプセル中の薬剤の噴霧乾燥ディスパーションからの迅速な溶解を達成するための製剤 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101346128B (zh) * | 2005-10-25 | 2013-10-02 | 雅培制药有限公司 | 包含低水溶解度药物的配方及其使用方法 |
| WO2007066189A2 (en) * | 2005-12-09 | 2007-06-14 | Pfizer Products Inc. | Salts, prodrugs and formulations of 1-[5-(4-amino-7-isopropyl-7h-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-2-methoxy-phenyl]-3-(2,4-dichloro-phenyl)-urea |
| WO2008055966A1 (en) * | 2006-11-09 | 2008-05-15 | Abbott Gmbh & Co. Kg | Pharmaceutical dosage form for oral administration of tyrosine kinase inhibitor |
-
2008
- 2008-10-17 JP JP2010529408A patent/JP2011500649A/ja active Pending
- 2008-10-17 CA CA2699301A patent/CA2699301A1/en not_active Abandoned
- 2008-10-17 MX MX2010004291A patent/MX2010004291A/es not_active Application Discontinuation
- 2008-10-17 BR BRPI0818340 patent/BRPI0818340A2/pt not_active IP Right Cessation
- 2008-10-17 RU RU2010119929/15A patent/RU2010119929A/ru not_active Application Discontinuation
- 2008-10-17 WO PCT/EP2008/064076 patent/WO2009050291A2/en not_active Ceased
- 2008-10-17 UA UAA201006029A patent/UA100865C2/ru unknown
- 2008-10-17 AU AU2008313622A patent/AU2008313622A1/en not_active Abandoned
- 2008-10-17 EP EP08839333A patent/EP2197425A2/en not_active Withdrawn
- 2008-10-17 KR KR1020107010979A patent/KR20100087170A/ko not_active Withdrawn
- 2008-10-17 PA PA20088800101A patent/PA8800101A1/es unknown
- 2008-10-17 CN CN200880112150A patent/CN101827584A/zh active Pending
-
2010
- 2010-03-24 ZA ZA2010/02095A patent/ZA201002095B/en unknown
- 2010-04-16 GT GT201000102A patent/GT201000102A/es unknown
- 2010-04-16 DO DO2010000117A patent/DOP2010000117A/es unknown
- 2010-04-27 CO CO10049271A patent/CO6270206A2/es not_active Application Discontinuation
- 2010-05-17 EC EC2010010183A patent/ECSP10010183A/es unknown
- 2010-05-19 CR CR11442A patent/CR11442A/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| PA8800101A1 (es) | 2009-05-15 |
| JP2011500649A (ja) | 2011-01-06 |
| GT201000102A (es) | 2012-03-12 |
| RU2010119929A (ru) | 2011-11-27 |
| EP2197425A2 (en) | 2010-06-23 |
| BRPI0818340A2 (pt) | 2015-04-22 |
| ECSP10010183A (es) | 2010-06-29 |
| MX2010004291A (es) | 2010-08-02 |
| WO2009050291A2 (en) | 2009-04-23 |
| CN101827584A (zh) | 2010-09-08 |
| KR20100087170A (ko) | 2010-08-03 |
| DOP2010000117A (es) | 2010-05-15 |
| CO6270206A2 (es) | 2011-04-20 |
| CR11442A (es) | 2010-09-06 |
| UA100865C2 (ru) | 2013-02-11 |
| CA2699301A1 (en) | 2009-04-23 |
| WO2009050291A3 (en) | 2010-04-08 |
| AU2008313622A1 (en) | 2009-04-23 |
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