[go: up one dir, main page]

ZA200805651B - Thermoreversible oil-in-water emulsion - Google Patents

Thermoreversible oil-in-water emulsion

Info

Publication number
ZA200805651B
ZA200805651B ZA200805651A ZA200805651A ZA200805651B ZA 200805651 B ZA200805651 B ZA 200805651B ZA 200805651 A ZA200805651 A ZA 200805651A ZA 200805651 A ZA200805651 A ZA 200805651A ZA 200805651 B ZA200805651 B ZA 200805651B
Authority
ZA
South Africa
Prior art keywords
water emulsion
thermoreversible
oil
thermoreversible oil
emulsion
Prior art date
Application number
ZA200805651A
Inventor
Marie-Francoise Klucker
Jean Haensler
Patricia Probeck-Quellec
Pascal Chaux
Original Assignee
Sanofi Pasteur
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Pasteur filed Critical Sanofi Pasteur
Publication of ZA200805651B publication Critical patent/ZA200805651B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/245—Herpetoviridae, e.g. herpes simplex virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
    • C12N2710/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
    • C12N2710/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16211—Influenzavirus B, i.e. influenza B virus
    • C12N2760/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ZA200805651A 2006-01-13 2007-01-09 Thermoreversible oil-in-water emulsion ZA200805651B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0600309A FR2896162B1 (en) 2006-01-13 2006-01-13 EMULSION OIL IN THERMOREVERSIBLE WATER

Publications (1)

Publication Number Publication Date
ZA200805651B true ZA200805651B (en) 2010-07-28

Family

ID=37103105

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200805651A ZA200805651B (en) 2006-01-13 2007-01-09 Thermoreversible oil-in-water emulsion

Country Status (14)

Country Link
US (1) US9504659B2 (en)
EP (1) EP1976560B1 (en)
JP (1) JP5226534B2 (en)
KR (1) KR20080091808A (en)
CN (2) CN101636178A (en)
AR (1) AR060018A1 (en)
AU (1) AU2007204295B2 (en)
BR (1) BRPI0706527A2 (en)
CA (1) CA2635724A1 (en)
FR (1) FR2896162B1 (en)
IL (1) IL192475A (en)
MX (1) MX2008009024A (en)
WO (1) WO2007080308A2 (en)
ZA (1) ZA200805651B (en)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7082569B2 (en) 2001-01-17 2006-07-25 Outlooksoft Corporation Systems and methods providing dynamic spreadsheet functionality
NZ561822A (en) 2005-03-23 2010-04-30 Glaxosmithkline Biolog Sa Multivalent influenza virus vaccine
JP5639760B2 (en) 2006-07-17 2014-12-10 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム Influenza vaccine
CA2680237C (en) 2007-03-27 2018-11-06 Sea Lane Biotechnologies, Llc Constructs and libraries comprising antibody surrogate light chain sequences
PE20090146A1 (en) 2007-04-20 2009-03-23 Glaxosmithkline Biolog Sa IMMUNOGENIC COMPOSITION AGAINST THE INFLUENZA VIRUS
GB0714963D0 (en) 2007-08-01 2007-09-12 Novartis Ag Compositions comprising antigens
JP5518041B2 (en) 2008-03-18 2014-06-11 ノバルティス アーゲー Improvements in the preparation of influenza virus vaccine antigens
US20100040635A1 (en) 2008-03-28 2010-02-18 Sea Lane Biotechnologies Neutralizing antibodies to influenza viruses
DK2268823T3 (en) 2008-08-28 2011-10-03 Novartis Ag Preparation of squalene from hyper-producing yeasts
NZ591768A (en) 2008-09-18 2012-11-30 Novartis Ag Vaccine adjuvant combinations
EA023662B1 (en) 2009-02-10 2016-06-30 Новартис Аг Influenza vaccines with reduced amounts of squalene
KR20110132373A (en) 2009-02-10 2011-12-07 노파르티스 아게 Influenza Vaccine Therapy for Pandemic-Related Weeks
CA2752041A1 (en) 2009-02-10 2010-08-19 Novartis Ag Influenza vaccines with increased amounts of h3 antigen
CA2752809A1 (en) * 2009-02-17 2010-08-26 Glaxosmithkline Biologicals Sa Inactivated dengue virus vaccine with aluminium-free adjuvant
CN109248313B (en) 2009-04-14 2023-01-17 葛兰素史密丝克莱恩生物有限公司 Compositions for immunization against staphylococcus aureus
CA2761681A1 (en) 2009-05-13 2010-11-18 Sea Lane Biotechnologies, Llc Neutralizing molecules to influenza viruses
JP5836266B2 (en) 2009-05-21 2015-12-24 ノバルティス アーゲー Reverse genetics using a non-endogenous polI promoter
EP2459722B1 (en) 2009-07-31 2017-09-06 Seqirus UK Limited Reverse genetics systems
US20110052633A1 (en) * 2009-09-02 2011-03-03 National Health Research Institutes Multi-phase emulsions based on amphiphilic block copolymers
GB0918392D0 (en) 2009-10-20 2009-12-02 Novartis Ag Diagnostic and therapeutic methods
CA2778332A1 (en) 2009-10-20 2011-04-28 Novartis Ag Improved reverse genetics methods for virus rescue
GB0919117D0 (en) 2009-10-30 2009-12-16 Glaxosmithkline Biolog Sa Process
GB0919690D0 (en) 2009-11-10 2009-12-23 Guy S And St Thomas S Nhs Foun compositions for immunising against staphylococcus aureus
DE102009056883B4 (en) 2009-12-03 2012-08-16 Novartis Ag Vaccine adjuvants and improved methods of making the same
DE102009056884B4 (en) 2009-12-03 2021-03-18 Novartis Ag Vaccine Adjuvants and Improved Methods for Making Same
SI2380558T2 (en) 2009-12-03 2019-11-29 Novartis Ag Arranging interaction and back pressure chambers for microfluidization
DE102009056871A1 (en) 2009-12-03 2011-06-22 Novartis AG, 4056 Vaccine adjuvants and improved methods of making the same
PL2343052T3 (en) 2009-12-03 2013-11-29 Novartis Ag Hydrophilic filtration during manufacture of vaccine adjuvants
ES2975170T3 (en) 2009-12-03 2024-07-03 Seqirus Uk Ltd Circulation of the components during the homogenization of the emulsions
BR112012022896A2 (en) 2010-03-18 2018-03-27 Novartis Ag adjuvant vaccines for serogroup b meningococci
ES2817446T3 (en) 2010-05-12 2021-04-07 Novartis Ag Improved methods for the preparation of squalene
EP2571520B1 (en) 2010-05-21 2018-04-04 Seqirus UK Limited Influenza virus reassortment method
GB201009861D0 (en) 2010-06-11 2010-07-21 Novartis Ag OMV vaccines
EP2646049B1 (en) 2010-12-03 2018-05-02 Sanofi Pasteur Limited Composition for immunization against streptococcus pneumoniae
ES2612511T3 (en) 2011-01-27 2017-05-17 Glaxosmithkline Biologicals Sa Adjuvant nanoemulsions with crystallization inhibitors
TR201811280T4 (en) 2011-03-02 2018-08-27 Glaxosmithkline Biologicals Sa Mixed vaccines with low antigen and / or adjuvant doses.
EP2688590B1 (en) 2011-03-24 2020-02-12 GlaxoSmithKline Biologicals SA Adjuvant nanoemulsions with phospholipids
EP2736928B1 (en) 2011-07-28 2019-01-09 i2 Pharmaceuticals, Inc. Sur-binding proteins against erbb3
JP2014527969A (en) 2011-09-19 2014-10-23 ジェンシア コーポレイション Modified creatine compound
AU2012324398A1 (en) 2011-10-20 2014-05-01 Seqirus UK Limited Adjuvanted influenza B virus vaccines for pediatric priming
CA2859744A1 (en) 2011-12-22 2013-06-27 Sea Lane Biotechnologies, Llc Surrogate binding proteins
CN104023744A (en) 2011-12-23 2014-09-03 诺华股份有限公司 Stable compositions for immunising against staphylococcus aureus
WO2013119856A1 (en) * 2012-02-07 2013-08-15 Infectious Disease Research Institute Improved adjuvant formulations comprising tlr4 agonists and methods of using the same
MX356507B (en) * 2012-02-10 2018-05-31 Soane Energy Llc Rapidly inverting water-in-oil polymer emulsions.
ES2628301T3 (en) 2012-03-02 2017-08-02 Seqirus UK Limited Recombination of influenza virus
CA2866406A1 (en) 2012-03-08 2013-09-12 Novartis Ag Adjuvanted formulations of booster vaccines
JP2015526062A (en) 2012-06-04 2015-09-10 ノバルティス アーゲー Improved safety testing
WO2013184900A2 (en) 2012-06-06 2013-12-12 Sanofi Pasteur Biologics, Llc Immunogenic compositions and related methods
HK1212905A1 (en) 2012-07-24 2016-06-24 Sanofi Pasteur Vaccine compositions for prevention against dengue virus infection
US20150196631A1 (en) 2012-07-24 2015-07-16 Sanofi Pasteur Vaccine compositions
WO2014033191A1 (en) 2012-08-31 2014-03-06 Novartis Ag Stabilised proteins for immunising against staphylococcus aureus
PT2890394T (en) 2012-08-31 2019-07-15 Glaxosmithkline Biologicals Sa Stabilised proteins for immunising against staphylococcus aureus
AU2013311702A1 (en) 2012-09-06 2015-02-19 Novartis Ag Combination vaccines with serogroup B meningococcus and D/T/P
SG11201502599TA (en) 2012-10-12 2015-05-28 Glaxosmithkline Biolog Sa Non-cross-linked acellular pertussis antigens for use in combination vaccines
DK2925355T3 (en) 2012-11-30 2018-01-15 Glaxosmithkline Biologicals Sa PSEUDOMONAS ANTIGENES AND ANTIGEN COMBINATIONS
WO2014083194A1 (en) 2012-11-30 2014-06-05 Sanofi Pasteur Methods for inducing antibodies
EP2925356A2 (en) 2012-12-03 2015-10-07 Novartis AG Reassortant influenza a viren
US20150320852A1 (en) 2012-12-18 2015-11-12 Glaxosmithkline Biologicals Sa Conjugates for protecting against diphtheria and/or tetanus
EP2968512A2 (en) 2013-03-13 2016-01-20 Novartis AG Influenza b virus reassortment
BR112015028314A2 (en) 2013-05-10 2017-09-19 Steinman Lawrence PREVENTION OF THE RISK OF NARCOLEPSY IN FLU VACCINES
DE202013005100U1 (en) 2013-06-05 2013-08-26 Novartis Ag Influenza virus reassortment
DE202013005130U1 (en) 2013-06-05 2013-09-10 Novartis Ag Influenza virus reassortment
AU2014276418A1 (en) 2013-06-06 2016-01-21 Novartis Ag Influenza virus reassortment
WO2014207708A2 (en) 2013-06-28 2014-12-31 Auckland Uniservices Limited Amino acid and peptide conjugates and conjugation process
BR112016015422A2 (en) 2013-12-31 2017-10-24 Infectious Disease Res Inst single vial vaccine formulations
MX377794B (en) 2014-03-26 2025-03-10 Glaxosmithkline Biologicals Sa MUTANT STAPHYLOCOCCAL ANTIGENS.
US10537860B2 (en) 2014-06-23 2020-01-21 Massachusetts Institute Of Technology Emulsions by condensation
AU2015370479B2 (en) 2014-12-23 2020-07-23 Auckland Uniservices Limited Amino acid and peptide conjugates and uses thereof
US10416171B2 (en) 2015-07-07 2019-09-17 Seqirus UK Limited Influenza potency assays
CN108367062B (en) 2015-10-13 2022-05-06 赛诺菲巴斯德有限公司 Immunogenic compositions against staphylococcus aureus
US9872832B2 (en) * 2015-10-23 2018-01-23 LG Bionano, LLC Nanoemulsions having reversible continuous and dispersed phases
KR101850417B1 (en) * 2015-12-16 2018-04-20 주식회사 휴벳바이오 Vaccine adjuvant composition based amphiphilic poly-amino acid including squalene
WO2017137085A1 (en) 2016-02-11 2017-08-17 Sanofi Pasteur Meningitidis vaccines comprising subtilinases
WO2017145097A2 (en) 2016-02-26 2017-08-31 Auckland Uniservices Limited Amino acid and peptide conjugates and conjugation process
CA3026108A1 (en) 2016-06-10 2017-12-14 Clarity Cosmetics Inc. Non-comedogenic hair and scalp care formulations and method for use
JP2020533354A (en) 2017-09-13 2020-11-19 サノフィ・パスツールＳａｎｏｆｉ Ｐａｓｔｅｕｒ Human cytomegalovirus immunogenic composition
CN108159414B (en) * 2018-01-15 2021-07-27 四川诺顺科技有限公司 Water-in-oil adjuvant for animal vaccine and preparation method and use thereof
BR112022009545A2 (en) 2019-11-18 2022-10-11 Seqirus Pty Ltd METHOD TO PRODUCE RECOMBINANT INFLUENZA VIRUS
AU2021302954A1 (en) 2020-06-30 2023-02-16 Seqirus UK Limited Cold filtration of oil-in-water emulsion adjuvants

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5547834A (en) 1988-01-29 1996-08-20 Chiron Corporation Recombinant CMV neutralizing proteins
CA2017507C (en) 1989-05-25 1996-11-12 Gary Van Nest Adjuvant formulation comprising a submicron oil droplet emulsion
US5302401A (en) * 1992-12-09 1994-04-12 Sterling Winthrop Inc. Method to reduce particle size growth during lyophilization
US20020102562A1 (en) 1995-05-24 2002-08-01 Pasteur Merieux Serums Et Vaccines S.A. Recombinant CMV neutralizing proteins
US5718904A (en) * 1995-06-02 1998-02-17 American Home Products Corporation Adjuvants for viral vaccines
US5744062A (en) * 1996-08-29 1998-04-28 R.I.T.A. Corporation Balanced emulsifier blends for oil-in-water emulsions
US6787523B1 (en) 1997-12-02 2004-09-07 Neuralab Limited Prevention and treatment of amyloidogenic disease
US20040006242A1 (en) 1999-02-01 2004-01-08 Hawkins Lynn D. Immunomodulatory compounds and method of use thereof
US6835721B2 (en) 1999-02-01 2004-12-28 Eisai Co., Ltd. Immunomodulatory compounds and methods of use thereof
CZ303515B6 (en) 1999-04-19 2012-11-07 Smithkline Beecham Biologicals S. A. Adjuvant compositions
US20030129251A1 (en) 2000-03-10 2003-07-10 Gary Van Nest Biodegradable immunomodulatory formulations and methods for use thereof
DE10025671B4 (en) * 2000-05-24 2006-07-27 Cognis Ip Management Gmbh emulsifiers
JP2006520746A (en) * 2002-12-27 2006-09-14 カイロン コーポレイション Immunogenic compositions comprising phospholipids
DE10318310A1 (en) * 2003-04-14 2004-11-25 Xaver Lipp Device for opening a valve, in particular an air inlet valve or gas outlet valve of a fermentation or digester
PL1651265T3 (en) * 2003-07-24 2008-10-31 Merial Ltd Vaccine formulations comprising an oil-in-water emulsion
US20050023729A1 (en) * 2003-07-31 2005-02-03 Smith Leslie E. Formation of wide paint film parts
DE10337451A1 (en) 2003-08-14 2005-03-17 Cognis Deutschland Gmbh & Co. Kg Use of PIT emulsions in enzymatic reactions
NZ561822A (en) * 2005-03-23 2010-04-30 Glaxosmithkline Biolog Sa Multivalent influenza virus vaccine
US7691368B2 (en) 2005-04-15 2010-04-06 Merial Limited Vaccine formulations
US20070292418A1 (en) * 2005-04-26 2007-12-20 Eisai Co., Ltd. Compositions and methods for immunotherapy
US8703095B2 (en) 2005-07-07 2014-04-22 Sanofi Pasteur S.A. Immuno-adjuvant emulsion
AU2006310337B9 (en) 2005-11-04 2013-11-28 Novartis Ag Adjuvanted influenza vaccines including cytokine-inducing agents
NZ594482A (en) 2005-11-04 2012-11-30 Novartis Vaccines & Diagnostic Influenza vaccines with reduced amount of oil-in-water emulsion as adjuvant

Also Published As

Publication number Publication date
MX2008009024A (en) 2009-03-05
IL192475A (en) 2014-06-30
FR2896162A1 (en) 2007-07-20
AR060018A1 (en) 2008-05-21
AU2007204295A1 (en) 2007-07-19
CN105709223A (en) 2016-06-29
WO2007080308A2 (en) 2007-07-19
FR2896162B1 (en) 2008-02-15
KR20080091808A (en) 2008-10-14
WO2007080308A3 (en) 2009-09-24
EP1976560A2 (en) 2008-10-08
JP2009523158A (en) 2009-06-18
CN101636178A (en) 2010-01-27
US20070191314A1 (en) 2007-08-16
JP5226534B2 (en) 2013-07-03
AU2007204295B2 (en) 2012-11-22
IL192475A0 (en) 2009-08-03
US9504659B2 (en) 2016-11-29
CA2635724A1 (en) 2007-07-19
EP1976560B1 (en) 2014-01-08
BRPI0706527A2 (en) 2011-03-29

Similar Documents

Publication Publication Date Title
ZA200805651B (en) Thermoreversible oil-in-water emulsion
PL3090729T3 (en) Emulsion
IL187967A0 (en) Thermoreversible immuno-adjuvant emulsion
EP1997474A4 (en) Water-in-oil emulsion type sunscreen preparation
IL178631A0 (en) Oil-in-water emulsion for delivery
EP2270121A4 (en) Oil-in-water type emulsion composition
EP2151230A4 (en) Oil-in-water emulsion composition and method for producing the same
EP2177201A4 (en) Oil-in-water emulsion composition and method for producing the same
EP2127635A4 (en) OIL-IN-WATER EMULSION COMPOSITION
ZA201108661B (en) Oil-in-water emulsion
ZA200804923B (en) Induced-viscosity nutritional emulsions
EP2067803A4 (en) Urethane emulsion
EP1842522A4 (en) Solid oil-in-water emulsion
ZA201108660B (en) Oil-in-water emulsion
EP2165695A4 (en) Water-in-oil type emulsion composition
GB0507468D0 (en) Emulsion separator
ZA200904101B (en) Edible aerated oil-and-water emulsion
PL1930307T3 (en) Hydrocarbon separation
GB0706563D0 (en) Emulsion grafting
FR2905069B1 (en) OIL-IN-WATER COSMETIC DISPERSION.
EP2060591A4 (en) Urethane emulsion
GB2420562B (en) Emulsion ink
GB0725382D0 (en) Typed application deployment
GB2422375B (en) Emulsion ink
GB0524022D0 (en) Emulsions