[go: up one dir, main page]

ZA200204493B - Pharmaceutical combinations and their use in treating gastrointestinal disorders. - Google Patents

Pharmaceutical combinations and their use in treating gastrointestinal disorders.

Info

Publication number
ZA200204493B
ZA200204493B ZA200204493A ZA200204493A ZA200204493B ZA 200204493 B ZA200204493 B ZA 200204493B ZA 200204493 A ZA200204493 A ZA 200204493A ZA 200204493 A ZA200204493 A ZA 200204493A ZA 200204493 B ZA200204493 B ZA 200204493B
Authority
ZA
South Africa
Prior art keywords
gastrointestinal disorders
pharmaceutical combinations
treating gastrointestinal
treating
pharmaceutical
Prior art date
Application number
ZA200204493A
Other languages
English (en)
Inventor
Billstein Stephan Anthony
Peter Dumovic
Nicola Franco
Iwicki Mark Thomas
Hans-Juergen Pfannkuche
Wilusz Edward Joseph Jr
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of ZA200204493B publication Critical patent/ZA200204493B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Otolaryngology (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA200204493A 1999-12-10 2002-06-05 Pharmaceutical combinations and their use in treating gastrointestinal disorders. ZA200204493B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US45838899A 1999-12-10 1999-12-10

Publications (1)

Publication Number Publication Date
ZA200204493B true ZA200204493B (en) 2003-09-29

Family

ID=23820591

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200204493A ZA200204493B (en) 1999-12-10 2002-06-05 Pharmaceutical combinations and their use in treating gastrointestinal disorders.

Country Status (30)

Country Link
EP (3) EP1286668B1 (xx)
JP (1) JP2003523324A (xx)
KR (1) KR100765579B1 (xx)
CN (2) CN1875966A (xx)
AR (1) AR026916A1 (xx)
AT (1) ATE293971T1 (xx)
AU (2) AU778869B2 (xx)
BR (1) BR0016275A (xx)
CA (1) CA2388959A1 (xx)
CO (1) CO5261535A1 (xx)
CZ (1) CZ300690B6 (xx)
DE (1) DE60019814T2 (xx)
DK (1) DK1286668T3 (xx)
ES (1) ES2240229T3 (xx)
HU (1) HUP0301122A3 (xx)
IL (2) IL149496A0 (xx)
MX (1) MXPA02005695A (xx)
MY (1) MY133423A (xx)
NO (1) NO20022680L (xx)
NZ (2) NZ531489A (xx)
PE (1) PE20011030A1 (xx)
PL (1) PL202201B1 (xx)
PT (1) PT1286668E (xx)
RU (1) RU2264215C2 (xx)
SG (1) SG152025A1 (xx)
SK (1) SK8062002A3 (xx)
TR (1) TR200402293T2 (xx)
TW (1) TWI263496B (xx)
WO (1) WO2001041748A2 (xx)
ZA (1) ZA200204493B (xx)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1284732A2 (en) * 2000-05-18 2003-02-26 Glaxo Group Limited Method for treating functional dyspepsia using alosetron
GB0209481D0 (en) * 2002-04-24 2002-06-05 Novartis Ag Organic compounds
KR20050094843A (ko) 2003-01-13 2005-09-28 다이노젠 파마세우티컬스, 인코포레이티드 욕지기, 구토, 구역질 또는 이들의 조합을 치료하는 방법
GB0307440D0 (en) * 2003-03-31 2003-05-07 Novartis Ag Organic compounds
RS20050868A (xx) * 2003-05-27 2007-08-03 Altana Pharma Ag., Farmaceutske kombinacije inhibotora protonske pumpe i jedinjenje koje modifikuje gastrointestinalni motilitet
US20050090554A1 (en) * 2003-09-12 2005-04-28 John Devane Treatment of gastroparesis and nonulcer dyspepsia with GABAB agonists
US7820690B2 (en) 2004-03-19 2010-10-26 Solvay Pharmaceuticals Gmbh Method of treating or inhibiting a non-digestive tract derived abdominal disorder associated with pain using a 5-HT, receptor antagonist
AU2005261778A1 (en) * 2004-07-14 2006-01-19 Novartis Ag Combination of DPP-IV inhibitors and compounds modulating 5-HT3 and/or 5-HT4 receptors
EP1853256A2 (en) * 2005-01-31 2007-11-14 Novartis AG Organic compounds
GB0506800D0 (en) * 2005-04-04 2005-05-11 Merck Sharp & Dohme New uses
US8324192B2 (en) 2005-11-12 2012-12-04 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
US8679545B2 (en) 2005-11-12 2014-03-25 The Regents Of The University Of California Topical corticosteroids for the treatment of inflammatory diseases of the gastrointestinal tract
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
EP1987009A1 (en) 2006-01-30 2008-11-05 Euro-Celtique S.A. Cyclourea compounds as calcium channel blockers
KR20090019914A (ko) * 2006-06-15 2009-02-25 노파르티스 아게 테가세로드를 단독으로 포함하거나 또는 양성자 펌프 억제제와 조합으로 포함하는, 위 손상의 치료 또는 예방용 조성물
WO2008130464A1 (en) 2007-02-09 2008-10-30 Tranzyme Pharma, Inc. Macrocyclic ghrelin receptor modulators and methods of using the same
LT3354276T (lt) * 2007-11-13 2020-04-27 Meritage Pharma, Inc. Kompozicijos, skirtos skrandžio ir žarnyno uždegimo gydymui
US20090123390A1 (en) 2007-11-13 2009-05-14 Meritage Pharma, Inc. Compositions for the treatment of gastrointestinal inflammation
GB201403775D0 (en) 2014-03-04 2014-04-16 Kymab Ltd Antibodies, uses & methods
WO2017220990A1 (en) 2016-06-20 2017-12-28 Kymab Limited Anti-pd-l1 antibodies
WO2018029474A2 (en) 2016-08-09 2018-02-15 Kymab Limited Anti-icos antibodies
US9567399B1 (en) 2016-06-20 2017-02-14 Kymab Limited Antibodies and immunocytokines
US11858996B2 (en) 2016-08-09 2024-01-02 Kymab Limited Anti-ICOS antibodies
US11779604B2 (en) 2016-11-03 2023-10-10 Kymab Limited Antibodies, combinations comprising antibodies, biomarkers, uses and methods
GB201709808D0 (en) 2017-06-20 2017-08-02 Kymab Ltd Antibodies
WO2019122882A1 (en) 2017-12-19 2019-06-27 Kymab Limited Bispecific antibody for icos and pd-l1
GB201721338D0 (en) 2017-12-19 2018-01-31 Kymab Ltd Anti-icos Antibodies
TW202313682A (zh) 2021-05-18 2023-04-01 英商凱麥博有限公司 抗icos抗體之用途
GB202107994D0 (en) 2021-06-04 2021-07-21 Kymab Ltd Treatment of cancer
WO2023222854A1 (en) 2022-05-18 2023-11-23 Kymab Limited Uses of anti-icos antibodies
FR3144752A1 (fr) 2023-01-10 2024-07-12 Song Huang Utilisation de polysulfate de pentosane pour le traitement de la toux seche

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT64023A (en) * 1991-03-22 1993-11-29 Sandoz Ag Process for producing aminoguanidine derivatives and pharmaceutical compositions comprising such compounds
EP0617620B1 (en) * 1991-12-21 1998-09-09 Smithkline Beecham Plc Use of 5-ht4 - antagonists for the manufacture of a medicament for the treatment of urinary incontinence
GB9214184D0 (en) * 1992-07-03 1992-08-12 Smithkline Beecham Plc Pharmaceuticals
US6156771A (en) * 1997-08-28 2000-12-05 Rubin; Walter Method for alleviation of lower gastrointestinal disorders in a human patient
GB9721139D0 (en) * 1997-10-07 1997-12-03 Glaxo Group Ltd Medicaments

Also Published As

Publication number Publication date
DE60019814D1 (de) 2005-06-02
IL149496A (en) 2009-12-24
WO2001041748A3 (en) 2002-12-19
MXPA02005695A (es) 2002-09-18
CN1875966A (zh) 2006-12-13
CN1409634A (zh) 2003-04-09
IL149496A0 (en) 2002-11-10
PT1286668E (pt) 2005-08-31
PE20011030A1 (es) 2001-10-31
NZ531489A (en) 2005-09-30
BR0016275A (pt) 2002-08-27
CZ20021967A3 (cs) 2002-08-14
SG152025A1 (en) 2009-05-29
MY133423A (en) 2007-11-30
RU2002118316A (ru) 2004-02-20
ES2240229T3 (es) 2005-10-16
AU2005200797B2 (en) 2008-01-24
DK1286668T3 (da) 2005-08-15
CN1310644C (zh) 2007-04-18
NZ566800A (en) 2009-11-27
NO20022680L (no) 2002-08-12
HUP0301122A3 (en) 2005-03-29
EP1286668B1 (en) 2005-04-27
KR20030016208A (ko) 2003-02-26
EP1913944A1 (en) 2008-04-23
ATE293971T1 (de) 2005-05-15
PL202201B1 (pl) 2009-06-30
SK8062002A3 (en) 2003-04-01
PL355663A1 (en) 2004-05-04
CZ300690B6 (cs) 2009-07-15
AU778869B2 (en) 2004-12-23
EP1286668A2 (en) 2003-03-05
HUP0301122A2 (hu) 2003-08-28
DE60019814T2 (de) 2006-03-02
TWI263496B (en) 2006-10-11
EP1488788A1 (en) 2004-12-22
AU2005200797A1 (en) 2005-03-17
NO20022680D0 (no) 2002-06-06
CA2388959A1 (en) 2001-06-14
WO2001041748A2 (en) 2001-06-14
KR100765579B1 (ko) 2007-10-09
RU2264215C2 (ru) 2005-11-20
JP2003523324A (ja) 2003-08-05
AR026916A1 (es) 2003-03-05
AU2672801A (en) 2001-06-18
TR200402293T2 (tr) 2004-10-21
CO5261535A1 (es) 2003-03-31

Similar Documents

Publication Publication Date Title
ZA200204493B (en) Pharmaceutical combinations and their use in treating gastrointestinal disorders.
AU2001293553A1 (en) Phosphatidylserine-carrying apoptosis-mimicking bodies and the use thereof in medical treatment
GB0109414D0 (en) Well treatment fluids and methods for the use thereof
HK1062914A1 (en) Glucopyranosyloxypyrazole derivatives and use thereof in medicines
HUP0203430A3 (en) Quinazolinones and their use
ZA200204390B (en) Caspase inhibitors and uses thereof.
EP0924983A4 (en) S (-) - TOLTERODINE FOR THE TREATMENT OF URINARY AND GASTROINTESTINAL DISORDERS
MXPA03004915A (es) Antagonistas de mch y su uso en el tratamiento de la obesidad.
AU4583601A (en) Peptidase-cleavable, targeted antineoplastic drugs and their therapeutic use
HUP0400069A3 (en) Pharmaceutical combinations and their use in preventing and treating the thrombosis
HK1061212A1 (en) Pyranoindazoles and their use for the treatment ofglaucoma
ZA200203156B (en) Use of dipyridamole or mopidamol in the manufacture of a medicament for the treatment and prevention of fibrindependent microcirculation disorders.
HK1043059A1 (en) Tumor necrosis factor antagonists and their use inendometriosis.
HK1031725A1 (en) 3-amino-3-arylpropan-1-ol-derivates, their preparation and their use
ZA97741B (en) Pharmaceutical combined preparation and its use in the treatment of gynaecological disorders.
AU2002243363A1 (en) Use of aziridino-compounds in the treatment of immune dysfunctions
GB2370233B (en) Apparatus for use in behaviour modification and the like
ZA982136B (en) Novel carboxylic acid derivatives, their preparation and use in treating cancer.
ZA200205464B (en) Device for preventing or relieving pain in the lower back.
HUP0105351A3 (en) Effervescent laxatives and their use
PL338123A1 (en) 6-pyrrolydin-2-ylpyridines, their production and application in therapy
HK1053266A1 (en) Pharmaceutical combinations and their use in treating gastrointestinal disorders
SI1043306T1 (en) 3-amino-3-arylpropan-1-ol-derivates, their preparation and use
SI1286668T1 (en) Pharmaceutical combinations comprising tegaserod und omeprazole and their use in treating gastrointestinal disorders
GB9929581D0 (en) Comjpositions and their use