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YU57396A - Processes and intermediates for preparaing 1-/2-2-isoxazol-3- ylbenzofuran-5-yloxy)ethylamino)-3-phenoxy-2(s)-ole - Google Patents

Processes and intermediates for preparaing 1-/2-2-isoxazol-3- ylbenzofuran-5-yloxy)ethylamino)-3-phenoxy-2(s)-ole

Info

Publication number
YU57396A
YU57396A YU57396A YU57396A YU57396A YU 57396 A YU57396 A YU 57396A YU 57396 A YU57396 A YU 57396A YU 57396 A YU57396 A YU 57396A YU 57396 A YU57396 A YU 57396A
Authority
YU
Yugoslavia
Prior art keywords
formula
ylbenzofuran
preparaing
isoxazol
ole
Prior art date
Application number
YU57396A
Other languages
Serbo-Croatian (sh)
Inventor
Michael Devries Keith
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of YU57396A publication Critical patent/YU57396A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Proces za dobijanje jedinjenja formule tretiranjem jedinjenja formule sa vodenim rastvorom neke mineralne kiseline gde R1 je vodonik i R2 i R3 zajedno formiraju jednostruku vezu ili R1 i R2 zajedno formiraju jednostruku vezu i R3 je vodonik ili grupa formule Jedinjenja formule I i njihove farmaceutski prihvatljive soli su korisni kao hipoglikemijski i antigojazni agensi. Oni su takodje korisni za povećanje nemasnog dela mesa u odnosu na masni kod životinja koje se koriste u ishrani na primer kod živine i papkara.A process for preparing a compound of formula by treating a compound of formula with an aqueous solution of a mineral acid wherein R 1 is hydrogen and R 2 and R 3 together form a single bond or R 1 and R 2 together form a single bond and R 3 is hydrogen or a group of formula Compounds of formula I and their pharmaceutically acceptable salts are useful as hypoglycemic and antihypertensive agents. They are also useful for increasing the lean portion of meat compared to fatty in animals used in the diet for example in poultry and ungulates.

YU57396A 1995-10-31 1996-10-30 Processes and intermediates for preparaing 1-/2-2-isoxazol-3- ylbenzofuran-5-yloxy)ethylamino)-3-phenoxy-2(s)-ole YU57396A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US815395P 1995-10-31 1995-10-31

Publications (1)

Publication Number Publication Date
YU57396A true YU57396A (en) 1998-11-05

Family

ID=21730067

Family Applications (1)

Application Number Title Priority Date Filing Date
YU57396A YU57396A (en) 1995-10-31 1996-10-30 Processes and intermediates for preparaing 1-/2-2-isoxazol-3- ylbenzofuran-5-yloxy)ethylamino)-3-phenoxy-2(s)-ole

Country Status (15)

Country Link
EP (1) EP0861240A1 (en)
JP (1) JPH10513480A (en)
KR (1) KR19990067172A (en)
CN (1) CN1201455A (en)
AU (1) AU6628596A (en)
BR (1) BR9611217A (en)
CA (1) CA2234081A1 (en)
CZ (1) CZ130898A3 (en)
HR (1) HRP960502A2 (en)
HU (1) HUP9900090A3 (en)
IL (1) IL123623A0 (en)
PL (1) PL327997A1 (en)
TR (1) TR199800710T2 (en)
WO (1) WO1997016432A1 (en)
YU (1) YU57396A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120253481A1 (en) * 2011-03-29 2012-10-04 General Electric Company Hart channel interface component including redundancy
EP2653464B1 (en) 2012-04-20 2017-09-27 Rohm and Haas Company Benzylamine hydrophobe

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0703911B1 (en) * 1993-06-14 1997-07-02 Pfizer Inc. Secondary amines as antidiabetic and antiobesity agents

Also Published As

Publication number Publication date
AU6628596A (en) 1997-05-22
PL327997A1 (en) 1999-01-04
HUP9900090A3 (en) 1999-11-29
CN1201455A (en) 1998-12-09
HRP960502A2 (en) 1998-04-30
MX9803497A (en) 1998-09-30
EP0861240A1 (en) 1998-09-02
WO1997016432A1 (en) 1997-05-09
KR19990067172A (en) 1999-08-16
BR9611217A (en) 1999-04-06
JPH10513480A (en) 1998-12-22
CA2234081A1 (en) 1997-05-09
TR199800710T2 (en) 1998-08-21
HUP9900090A2 (en) 1999-10-28
CZ130898A3 (en) 1999-03-17
IL123623A0 (en) 1998-10-30

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