YU47911B - PROCEDURE FOR OBTAINING A CONTRAST ENVIRONMENT - Google Patents
PROCEDURE FOR OBTAINING A CONTRAST ENVIRONMENTInfo
- Publication number
- YU47911B YU47911B YU50390A YU50390A YU47911B YU 47911 B YU47911 B YU 47911B YU 50390 A YU50390 A YU 50390A YU 50390 A YU50390 A YU 50390A YU 47911 B YU47911 B YU 47911B
- Authority
- YU
- Yugoslavia
- Prior art keywords
- contrast
- procedure
- obtaining
- medium
- necessary
- Prior art date
Links
- 239000002872 contrast media Substances 0.000 abstract 4
- 229910001415 sodium ion Inorganic materials 0.000 abstract 2
- AMDBBAQNWSUWGN-UHFFFAOYSA-N Ioversol Chemical group OCCN(C(=O)CO)C1=C(I)C(C(=O)NCC(O)CO)=C(I)C(C(=O)NCC(O)CO)=C1I AMDBBAQNWSUWGN-UHFFFAOYSA-N 0.000 abstract 1
- FKNQFGJONOIPTF-UHFFFAOYSA-N Sodium cation Chemical compound [Na+] FKNQFGJONOIPTF-UHFFFAOYSA-N 0.000 abstract 1
- 239000008135 aqueous vehicle Substances 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 238000007865 diluting Methods 0.000 abstract 1
- 239000006185 dispersion Substances 0.000 abstract 1
- 229960004537 ioversol Drugs 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 abstract 1
- 239000001509 sodium citrate Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
- A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
- Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
- Devices For Indicating Variable Information By Combining Individual Elements (AREA)
- Liquid Crystal (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Lubricants (AREA)
- Steroid Compounds (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Abstract
POSTUPAK ZA DOBIJANJE KONTRASTNE SREDINE, naznačen time, što obuhvata mešanje, po potrebi posle disperovanja u fiziološki prihvatljivoj sredini vodenog nosača, nejonskog jodovanog kontrastnog agensa za rendgensko snimanje i izvora natrijumovih jona, i ako je potrebno razblaživanje dobijene smeše da bi se proizvela kontrastna sredina koja ima koncentraciju natrijumovih jona veću od 20 mM pa do 60 mM, ili 26 do 60 mM kada je prisutan natrijum citrat, ili 26 do 36 mM kada je pomenuti kontrastni agens joverzol. Prijava sadrži još 9 zavisnih zahteva.PROCESS FOR PREPARING A CONTRAST MEDIUM, comprising mixing, if necessary after dispersion in a physiologically acceptable aqueous vehicle medium, a non-ionic iodinated X-ray contrast agent and a source of sodium ions, and if necessary diluting the resulting mixture to produce a contrast medium has a sodium ion concentration greater than 20 mM to 60 mM, or 26 to 60 mM when sodium citrate is present, or 26 to 36 mM when said contrast agent is joversol. The application contains 9 more dependent requests.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB898906130A GB8906130D0 (en) | 1989-03-17 | 1989-03-17 | Compositions |
Publications (2)
Publication Number | Publication Date |
---|---|
YU50390A YU50390A (en) | 1994-01-20 |
YU47911B true YU47911B (en) | 1996-05-20 |
Family
ID=10653498
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU50390A YU47911B (en) | 1989-03-17 | 1990-03-14 | PROCEDURE FOR OBTAINING A CONTRAST ENVIRONMENT |
Country Status (32)
Country | Link |
---|---|
US (1) | US5366722B1 (en) |
EP (2) | EP0390242B1 (en) |
JP (1) | JP2977045B2 (en) |
KR (1) | KR920700701A (en) |
CN (1) | CN1057703C (en) |
AT (1) | ATE123954T1 (en) |
AU (1) | AU638235B2 (en) |
BG (1) | BG60951B1 (en) |
CA (1) | CA2046886A1 (en) |
CZ (1) | CZ281381B6 (en) |
DD (1) | DD295992A5 (en) |
DE (1) | DE69020208T2 (en) |
DK (1) | DK0390242T3 (en) |
EG (1) | EG19431A (en) |
ES (1) | ES2073505T3 (en) |
FI (1) | FI914337A0 (en) |
GB (1) | GB8906130D0 (en) |
GR (1) | GR3017133T3 (en) |
HU (1) | HU206835B (en) |
IE (1) | IE67885B1 (en) |
IL (1) | IL93752A (en) |
JO (1) | JO1619B1 (en) |
NO (1) | NO302064B1 (en) |
NZ (1) | NZ232954A (en) |
OA (1) | OA09392A (en) |
PT (1) | PT93471B (en) |
RO (1) | RO112246B1 (en) |
RU (1) | RU2088261C1 (en) |
TR (1) | TR25111A (en) |
WO (1) | WO1990011094A1 (en) |
YU (1) | YU47911B (en) |
ZA (1) | ZA902052B (en) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8919929D0 (en) * | 1989-09-04 | 1989-10-18 | Nycomed As | Compositions |
US5614638A (en) * | 1989-11-29 | 1997-03-25 | Bracco International B.V. | Nonionic radiographic contrast agents |
US5869024A (en) * | 1989-11-29 | 1999-02-09 | Bracco International B.V. | Methods and compositions for using non-ionic contrast agents to reduce the risk of clot formation in diagnostic procedures |
GB9020091D0 (en) * | 1990-09-14 | 1990-10-24 | Nycomed As | Contrast media |
RU2098131C1 (en) | 1990-03-09 | 1997-12-10 | Нюкомед Имагинг А.С. | Contrasting medium and a method of its preparing |
US5527926A (en) * | 1990-11-26 | 1996-06-18 | Bracco International B.V. | Methods and compositions for using non-ionic contrast agents to reduce the risk of clot formation in diagnostic procedures |
US5278311A (en) * | 1992-06-05 | 1994-01-11 | E. R. Squibb & Sons, Inc. | Nonionic radiographic contrast agents |
IT1256248B (en) * | 1992-12-24 | 1995-11-29 | Bracco Spa | WATER INJECTABLE FORMULATIONS FOR RADIODIAGNOSTICS INCLUDING MIXTURES OF IODURATED AROMATIC COMPOUNDS USEFUL AS X-RAY MATTING AGENTS |
GB9419203D0 (en) * | 1994-09-23 | 1994-11-09 | Nycomed Innovation Ab | Contrast media |
GB9419206D0 (en) * | 1994-09-23 | 1994-11-09 | Nycomed Innovation Ab | Contrast media |
EP0876140B1 (en) * | 1996-01-25 | 2003-10-15 | Schering Aktiengesellschaft | Improved kontrast agent solutions for intravenous administration |
EP0885616A1 (en) * | 1997-06-20 | 1998-12-23 | Schering Aktiengesellschaft | Use of intravenous contrast agents, and apparatus for projectionsmammography |
EP2493511B1 (en) | 2009-10-29 | 2013-10-16 | GE Healthcare AS | Diagnostic composition comprising plasma cations having a superior safety profile |
KR101915821B1 (en) * | 2010-03-23 | 2018-11-06 | 지이 헬스케어 에이에스 | Preparation of stabilised x-ray diagnostic composition |
RU2662319C2 (en) | 2013-03-27 | 2018-07-25 | ДжиИ Хелткер АС | Method and reagent for preparing a diagnostic composition |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2909439A1 (en) * | 1979-03-08 | 1980-09-18 | Schering Ag | NEW NON-ionic x-ray contrast agents |
DE2928417A1 (en) * | 1979-07-12 | 1981-01-29 | Schering Ag | TRIJODIZED BASES |
DE3038853A1 (en) * | 1980-10-10 | 1982-05-27 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | NEW N-HYDROXY-ALKYLATED DICARBONIC ACID-BIS- (3,5-DICARBAMOYL-2,4,6-TRIJODANILIDES), THEIR PRODUCTION AND THEIR CONTAINING X-RAY CONTRAST AGENTS (II) |
US4957939A (en) * | 1981-07-24 | 1990-09-18 | Schering Aktiengesellschaft | Sterile pharmaceutical compositions of gadolinium chelates useful enhancing NMR imaging |
AU4500085A (en) * | 1984-06-22 | 1986-01-24 | R.L. Veech | Electrolyte solutions containing polyanionic materials |
WO1986000227A1 (en) * | 1984-06-22 | 1986-01-16 | Veech Richard L | Electrolyte solutions and in vivo use thereof |
US4863714A (en) * | 1987-02-05 | 1989-09-05 | Cook Imaging Corporation | Sterilization of compositions of limited stability |
US5011925A (en) * | 1989-03-09 | 1991-04-30 | Mallinckrodt, Inc. | Morpholinoamido EDTA derivatives |
-
1989
- 1989-03-17 GB GB898906130A patent/GB8906130D0/en active Pending
-
1990
- 1990-03-09 ES ES90200580T patent/ES2073505T3/en not_active Expired - Lifetime
- 1990-03-09 WO PCT/EP1990/000393 patent/WO1990011094A1/en not_active Application Discontinuation
- 1990-03-09 KR KR1019910701153A patent/KR920700701A/en not_active Application Discontinuation
- 1990-03-09 AU AU51854/90A patent/AU638235B2/en not_active Ceased
- 1990-03-09 JP JP2504207A patent/JP2977045B2/en not_active Expired - Lifetime
- 1990-03-09 RO RO148301A patent/RO112246B1/en unknown
- 1990-03-09 AT AT90200580T patent/ATE123954T1/en not_active IP Right Cessation
- 1990-03-09 DK DK90200580.0T patent/DK0390242T3/en active
- 1990-03-09 HU HU902356A patent/HU206835B/en not_active IP Right Cessation
- 1990-03-09 RU SU5010018/14A patent/RU2088261C1/en active
- 1990-03-09 CA CA002046886A patent/CA2046886A1/en not_active Withdrawn
- 1990-03-09 DE DE69020208T patent/DE69020208T2/en not_active Expired - Lifetime
- 1990-03-09 EP EP90200580A patent/EP0390242B1/en not_active Expired - Lifetime
- 1990-03-09 EP EP90904340A patent/EP0463013A1/en active Pending
- 1990-03-14 YU YU50390A patent/YU47911B/en unknown
- 1990-03-14 IL IL9375290A patent/IL93752A/en not_active IP Right Cessation
- 1990-03-15 CZ CS901257A patent/CZ281381B6/en unknown
- 1990-03-15 DD DD90338762A patent/DD295992A5/en not_active IP Right Cessation
- 1990-03-16 ZA ZA902052A patent/ZA902052B/en unknown
- 1990-03-16 TR TR90/0280A patent/TR25111A/en unknown
- 1990-03-16 IE IE97090A patent/IE67885B1/en not_active IP Right Cessation
- 1990-03-16 NZ NZ232954A patent/NZ232954A/en unknown
- 1990-03-16 PT PT93471A patent/PT93471B/en not_active IP Right Cessation
- 1990-03-17 CN CN90101396A patent/CN1057703C/en not_active Expired - Lifetime
- 1990-03-17 JO JO19901619A patent/JO1619B1/en active
- 1990-03-18 EG EG17490A patent/EG19431A/en active
-
1991
- 1991-08-19 OA OA60064A patent/OA09392A/en unknown
- 1991-09-16 FI FI914337A patent/FI914337A0/en not_active Application Discontinuation
- 1991-09-16 NO NO913641A patent/NO302064B1/en not_active IP Right Cessation
- 1991-10-16 BG BG95330A patent/BG60951B1/en unknown
-
1993
- 1993-11-24 US US08156998 patent/US5366722B1/en not_active Expired - Lifetime
-
1995
- 1995-08-16 GR GR950402252T patent/GR3017133T3/en unknown
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