YU201190A - Novi triazolilhidrazidni derivati i postupak za njihovo pravljenje - Google Patents
Novi triazolilhidrazidni derivati i postupak za njihovo pravljenjeInfo
- Publication number
- YU201190A YU201190A YU201190A YU201190A YU201190A YU 201190 A YU201190 A YU 201190A YU 201190 A YU201190 A YU 201190A YU 201190 A YU201190 A YU 201190A YU 201190 A YU201190 A YU 201190A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- group
- alkyl
- formula
- hydrogen
- stands
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 8
- 239000001257 hydrogen Substances 0.000 abstract 8
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 4
- 150000002431 hydrogen Chemical class 0.000 abstract 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
- 125000001425 triazolyl group Chemical group 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 abstract 1
- 208000007107 Stomach Ulcer Diseases 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000003257 anti-anginal effect Effects 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 201000005917 gastric ulcer Diseases 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G11—INFORMATION STORAGE
- G11B—INFORMATION STORAGE BASED ON RELATIVE MOVEMENT BETWEEN RECORD CARRIER AND TRANSDUCER
- G11B33/00—Constructional parts, details or accessories not provided for in the other groups of this subclass
- G11B33/02—Cabinets; Cases; Stands; Disposition of apparatus therein or thereon
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/14—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- G—PHYSICS
- G11—INFORMATION STORAGE
- G11B—INFORMATION STORAGE BASED ON RELATIVE MOVEMENT BETWEEN RECORD CARRIER AND TRANSDUCER
- G11B20/00—Signal processing not specific to the method of recording or reproducing; Circuits therefor
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Signal Processing (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Reinforced Plastic Materials (AREA)
- Chemical And Physical Treatments For Wood And The Like (AREA)
Abstract
NOVI TRIAZOLILHIDRAZIDNI DERIVATI I POSTUPAK ZA NJIHOVO PRAVLJENJE, ovaj pronalazak odnosi se na nove triazolilhidrazidne derivate i na postupak za njihovo pravljenje. Novi triazolilhidrazidni derivati opšte formule (I) pri čemu u formuli: Q predstavlja vodonik ili heterocikličnu grupu koja je opciono supstituisana sa C1-4 alkil grupom; ili grupu formule SR1, gde R1 predstavlja C1-4 alkil ili fenil-(C1-4alkil) koji je opciono supstituisan sa halogenom, C1-4 alkil ili nitro supstituentima; ili grupa opšte formule NR2R3 u kojoj R2 i R3 svaki predstavlja vodonik, C1-6 alkil ili C2-6 alkenil pravog ili račvastog niza ili C2-6 alkenil; Z predstavlja vodonik ili grupu formule (C=X)-(N-R4)-NR5R6, gde X predstavlja kiseonik ili sumpor, R4, R5 i R6 svaki predstavlja vodonik ili C1-4 alkil; R7 predstavlja vodonik C1-4alkil ili fenil-(C1-4alkil) koji je opciono supstituisan sa jednim ili više halogenskih atoma ili sa amino grupom koja je opciono supstituisana sa jednim ili dva C1-4 alkil supstituenta, R8 predstavlja vodonik ili grupu formule -(C=X)-(N-R4)NR5R6, gde su X, R4, R5 i R6 kao što je naznačeno gore, pod uslovom da ako Z predstavlja grupu formule -(C=X)-(N-R4)-NR5R6, R8 predstavlja vodonik, a ako Z predstavlja vodonik, R8 predstavlja grupu formule (C=X)-(N-R4)-NR5R6, i njihove farmaceutski prihvatljive adicione soli sa kiselinama, ispoljavaju dragocene osobine za inhibiranje stomačnog ulcera i korisni su u terapiji.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU895428A HU206095B (en) | 1989-10-25 | 1989-10-25 | Process for producing triazolylcarboxylc acid hydrazie and semicarbazide derivatives and pharmaceutical compositions comprising same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| YU201190A true YU201190A (sh) | 1993-10-20 |
| YU47564B YU47564B (sh) | 1995-10-03 |
Family
ID=10970291
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YU201190A YU47564B (sh) | 1989-10-25 | 1990-10-25 | Triazolilhidrazidni derivati i postupak za njihovo pravljenje |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5225410A (sh) |
| EP (1) | EP0425283B1 (sh) |
| JP (1) | JPH03246282A (sh) |
| KR (1) | KR910007895A (sh) |
| CN (1) | CN1051173A (sh) |
| AT (1) | ATE122343T1 (sh) |
| BG (1) | BG51044A3 (sh) |
| DE (2) | DE69019294T4 (sh) |
| DK (1) | DK0425283T3 (sh) |
| ES (1) | ES2076334T3 (sh) |
| FI (1) | FI905254A0 (sh) |
| HU (1) | HU206095B (sh) |
| IL (1) | IL96126A (sh) |
| IN (1) | IN171608B (sh) |
| PL (1) | PL164879B1 (sh) |
| RU (1) | RU2039051C1 (sh) |
| YU (1) | YU47564B (sh) |
| ZA (1) | ZA908557B (sh) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10126072C1 (de) | 2001-05-28 | 2002-11-28 | Martin Hofer Gmbh | Dämpferbein |
| JP4788181B2 (ja) * | 2005-04-13 | 2011-10-05 | パナソニック株式会社 | 表示パネルの組立装置 |
| JP4710410B2 (ja) * | 2005-05-10 | 2011-06-29 | パナソニック株式会社 | パネルのコネクタの接合装置および接合方法 |
| US8603392B2 (en) | 2010-12-21 | 2013-12-10 | Ecolab Usa Inc. | Electrolyzed water system |
| US8557178B2 (en) | 2010-12-21 | 2013-10-15 | Ecolab Usa Inc. | Corrosion inhibition of hypochlorite solutions in saturated wipes |
| US8114344B1 (en) | 2010-12-21 | 2012-02-14 | Ecolab Usa Inc. | Corrosion inhibition of hypochlorite solutions using sugar acids and Ca |
| CN103923033B (zh) * | 2013-01-14 | 2015-11-18 | 天津药物研究院 | 具有抗胃溃疡作用的哌嗪类衍生物 |
| CN110408048B (zh) * | 2019-09-04 | 2021-06-22 | 中国工程物理研究院化工材料研究所 | 一种不敏感含能金属有机框架及其制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2352944A (en) * | 1942-07-04 | 1944-07-04 | Gen Electric | Triazole derivatives |
| BE576586A (fr) * | 1958-03-17 | 1959-07-01 | France Etat | Nouveaux produits chimiques utilisables notamment comme régulateurs de la croissance des végétaux ou comme fongicides, leurs procédés de fabrication et leurs appalications. |
| FR1193374A (fr) * | 1958-03-17 | 1959-11-02 | Le Ministre De La Defense Nati | Nouveaux produits utilisables comme régulateurs de la croissance des végétaux |
| GB949170A (en) * | 1960-03-15 | 1964-02-12 | France Etat | Carbamyl and thiocarbamyl substances, methods for producing same and applications thereof |
| DE3809053A1 (de) * | 1988-03-18 | 1989-09-28 | Bayer Ag | Substituierte 5-amino-4h-1,2,4-triazol-3-yl-carbonsaeureamide, verfahren zu ihrer herstellung und ihre verwendung als herbizide |
-
1989
- 1989-10-25 HU HU895428A patent/HU206095B/hu not_active IP Right Cessation
-
1990
- 1990-10-25 KR KR1019900017151A patent/KR910007895A/ko not_active Application Discontinuation
- 1990-10-25 ZA ZA908557A patent/ZA908557B/xx unknown
- 1990-10-25 DK DK90311690.3T patent/DK0425283T3/da active
- 1990-10-25 PL PL90287506A patent/PL164879B1/pl unknown
- 1990-10-25 DE DE69019294T patent/DE69019294T4/de not_active Expired - Lifetime
- 1990-10-25 RU SU904831604A patent/RU2039051C1/ru active
- 1990-10-25 ES ES90311690T patent/ES2076334T3/es not_active Expired - Lifetime
- 1990-10-25 IL IL9612690A patent/IL96126A/en not_active IP Right Cessation
- 1990-10-25 YU YU201190A patent/YU47564B/sh unknown
- 1990-10-25 CN CN90108619A patent/CN1051173A/zh active Pending
- 1990-10-25 BG BG093093A patent/BG51044A3/xx unknown
- 1990-10-25 EP EP90311690A patent/EP0425283B1/en not_active Expired - Lifetime
- 1990-10-25 AT AT90311690T patent/ATE122343T1/de not_active IP Right Cessation
- 1990-10-25 FI FI905254A patent/FI905254A0/fi not_active IP Right Cessation
- 1990-10-25 DE DE69019294A patent/DE69019294D1/de not_active Expired - Fee Related
- 1990-10-25 US US07/604,488 patent/US5225410A/en not_active Expired - Fee Related
- 1990-10-25 JP JP2288248A patent/JPH03246282A/ja active Pending
- 1990-10-25 IN IN851/MAS/90A patent/IN171608B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69019294D1 (de) | 1995-06-14 |
| YU47564B (sh) | 1995-10-03 |
| CN1051173A (zh) | 1991-05-08 |
| FI905254A0 (fi) | 1990-10-25 |
| HU895428D0 (en) | 1990-01-28 |
| PL164879B1 (pl) | 1994-10-31 |
| ATE122343T1 (de) | 1995-05-15 |
| RU2039051C1 (ru) | 1995-07-09 |
| EP0425283A2 (en) | 1991-05-02 |
| DK0425283T3 (da) | 1995-07-10 |
| US5225410A (en) | 1993-07-06 |
| EP0425283A3 (en) | 1991-10-23 |
| DE69019294T2 (de) | 1995-09-07 |
| DE69019294T4 (de) | 1996-01-18 |
| JPH03246282A (ja) | 1991-11-01 |
| IN171608B (sh) | 1992-11-21 |
| EP0425283B1 (en) | 1995-05-10 |
| HUT59382A (en) | 1992-05-28 |
| PL287506A1 (en) | 1991-08-12 |
| IL96126A0 (en) | 1991-07-18 |
| ES2076334T3 (es) | 1995-11-01 |
| IL96126A (en) | 1994-11-11 |
| HU206095B (en) | 1992-08-28 |
| ZA908557B (en) | 1991-12-24 |
| BG51044A3 (en) | 1993-01-15 |
| KR910007895A (ko) | 1991-05-30 |
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