WO2025029949A1

WO2025029949A1 - Tips for skin treatment devices and systems

Info

Publication number: WO2025029949A1
Application number: PCT/US2024/040430
Authority: WO
Inventors: Ke Xu; Sheldon George PHILLIPS; Scott Garner; Joseph Wong
Original assignee: Hydrafacial LLC
Current assignee: Hydrafacial LLC
Priority date: 2023-08-01
Filing date: 2024-07-31
Publication date: 2025-02-06
Anticipated expiration: 2026-02-01

Abstract

According to some embodiments, a tip for a skin treatment device comprises a peripheral member (e.g., lip) located along a distal end of the tip, the peripheral member designed to contact a skin surface when the tip is secured to an end of the skin treatment device. The peripheral member defines an interior area along the distal end of the tip, and includes at least one interior member at least partially positioned within the interior area extending from a base in a distal direction. The peripheral member and the at least one interior member can have different flexibilities to assist the tip at least partially conform to skin surface during use. The tip can include a fluid delivery port to direct a treatment material to the interior area or region during use, and at least one waste port to transfer waste away from the interior area.

Description

EDGE.218WO PCT PATENT APPLICATION

TIPS FOR SKIN TREATMENT DEVICES AND SYSTEMS

Related Applications

[0001] This application claims priority to U.S. Provisional Patent Application No. 63/516918, filed August 1, 2023, the entire contents of which are incorporated herein by reference and made a part of this application.

Field

[0002] This application relates generally to skin treatment, and more specifically, to tips and methods for treating a person’s skin.

Description of the Related Art

[0003] Abrasion of the outer layer or epidermis of the skin is desirable to smooth or blend scars, blemishes, or other skin conditions that may be caused by, for example, acne, sun exposure, and aging. Standard techniques used to abrade the skin have generally been separated into two fields referred to as dermabrasion and microdermabrasion. Both techniques remove portions of the epidermis called the stratum comeum, which the body interprets as a mild injury. The body then replaces the lost skin cells, resulting in a new outer layer of skin. Additionally, despite the mild edema and erythema associated with the procedures, the skin looks and feels smoother because of the new outer layer of skin.

Summary

[0004] According to some embodiments, the techniques described herein relate to a tip for a skin treatment device, the tip including: a peripheral member (e.g., lip) located along a distal end of the tip, wherein the peripheral member is configured to contact a skin surface when the tip is secured to an end of the skin treatment device; wherein the peripheral member defines an interior area or region along the distal end of the tip; at least one interior member at least partially positioned within the interior area or region defined by the peripheral member; wherein the at least one interior member extends from a base distally in a direction of the distal end; wherein the peripheral member has a flexibility that is greater than a flexibility of the at least one interior member; and wherein the peripheral member is configured to at least partially conform to skin surface being treated during use; at least one fluid delivery port or opening in fluid communication with the interior area or region, the at least one fluid delivery port or

EDGE.218WO -1- Knobbe, Martens, Olson & Bear, LLP opening configured to direct a treatment material to the interior area or region during use; and at least one waste port or opening in fluid communication with the interior area or region, the at least one waste port or opening configured to transfer waste away from the interior area or region during use.

[0005] In some embodiments, the techniques described herein relate to a tip for a skin treatment device, the tip including: a peripheral member located along a distal end of the tip, wherein the peripheral member is configured to contact a skin surface when the tip is secured to an end of the skin treatment device; wherein the peripheral member defines an interior area or region along the distal end of the tip; at least one interior member at least partially positioned within the interior area or region defined by the peripheral member; wherein the at least one interior member extends from a base distally in a direction of the distal end; wherein the peripheral member has a flexibility that is greater than a flexibility of the at least one interior member; and wherein the peripheral member is configured to at least partially conform to skin surface being treated during use; at least one fluid delivery port or opening in fluid communication with the interior area or region, the at least one fluid delivery port or opening configured to direct a treatment material to the interior area or region during use; and at least one waste port or opening in fluid communication with the interior area or region, the at least one waste port or opening configured to transfer waste away from the interior area or region during use.

[0006] In some embodiments, the techniques described herein relate to a tip, wherein a durometer of the peripheral member is lower than a durometer of the at least one interior member or feature; wherein the at least one interior member includes at least one protruding member; and wherein the tip includes a distal portion and a proximal portion, wherein the distal portion includes the peripheral member and the at least one interior member, and wherein the proximal portion is configured to contact and secure to an end of the skin treatment device.

[0007] In some embodiments, the techniques described herein relate to a tip, wherein a durometer of the peripheral member is lower than a durometer of the at least one interior member or feature.

[0008] In some embodiments, the techniques described herein relate to a tip, wherein the at least one interior member includes at least one protruding member.

EDGE.218WO -2- Knobbe, Martens, Olson & Bear, LLP [0009] In some embodiments, the techniques described herein relate to a tip, wherein the at least one interior member includes a member having a spiral or curved shape.

[0010] In some embodiments, the techniques described herein relate to a tip, wherein the tip includes a distal portion and a proximal portion, wherein the distal portion includes the peripheral member and the at least one interior member, and wherein the proximal portion is configured to contact and secure to an end of the skin treatment device.

[0011] In some embodiments, the techniques described herein relate to a tip, wherein the proximal portion is secured to the distal portion of the tip during a friction fit or press fit connection.

[0012] In some embodiments, the techniques described herein relate to a tip, wherein the proximal portion is secured to the distal portion of the tip using at least one of an adhesive, a mechanical connection, a threaded connection and/or any other connection or coupling method or technology.

[0013] In some embodiments, the techniques described herein relate to a tip, wherein each of the peripheral member and the at least one interior member includes a flexible configuration.

[0014] In some embodiments, the techniques described herein relate to a tip, wherein the peripheral member includes an elastomeric or other flexible polymeric material.

[0015] In some embodiments, the techniques described herein relate to a tip, wherein at least a portion of the at least one interior member includes an abrasive material or feature.

[0016] In some embodiments, the techniques described herein relate to a tip, wherein the abrasive material or feature is positioned along a distal surface of the at least one interior member.

[0017] In some embodiments, the techniques described herein relate to a tip, wherein the abrasive material or feature is impregnated or otherwise embedded within at least a portion of the at least one interior member.

[0018] In some embodiments, the techniques described herein relate to a tip, wherein the peripheral member extends more distally relative to a distal-most end of the at least one interior member.

EDGE.218WO -3- Knobbe, Martens, Olson & Bear, LLP [0019] In some embodiments, the techniques described herein relate to a tip, wherein the at least one interior member extends to or substantially to a distal end of the peripheral member.

[0020] In some embodiments, the techniques described herein relate to a tip, wherein a distal end of the peripheral member is angled relative to both a longitudinal axis of the tip and an axis perpendicular to the longitudinal axis of the tip.

[0021] In some embodiments, the techniques described herein relate to a tip, wherein the angled distal end of the peripheral member enhances the flexibility of the peripheral member and an ability of the peripheral member to at least partially conform to a skin surface being treated during use.

[0022] In some embodiments, the techniques described herein relate to a tip, wherein at least a portion of the at least one interior member is configured to abrade or exfoliate skin tissue when the tip is moved relative to said skin tissue during use.

[0023] In some embodiments, the techniques described herein relate to a tip, wherein at least a portion of the at least one interior member is not configured to abrade or exfoliate skin tissue when the tip is moved relative to said skin tissue during use.

[0024] In some embodiments, the techniques described herein relate to a tip, wherein at least a portion of the at least one interior member includes at least one knub or other member or feature configured to provide a massaging effect on skin tissue being treated during use.

[0025] In some embodiments, the techniques described herein relate to a tip, wherein the tip is configured to be used in a microdermabrasion procedure.

[0026] In some embodiments, the techniques described herein relate to a tip, wherein a plane or face formed along a distal-most plane or face of the tip is angled relative to both a longitudinal axis of the tip and an axis perpendicular to the longitudinal axis of the tip.

[0027] In some embodiments, the techniques described herein relate to a tip, wherein the at least one interior member includes an edge or another surface that is configured to at least partially abrade or exfoliate skin tissue when the tip is moved relative to said skin tissue during use.

[0028] In some embodiments, the techniques described herein relate to a tip, wherein the tip is configured to be removably secured to an end of the skin treatment device.

EDGE.218WO -4- Knobbe, Martens, Olson & Bear, LLP [0029] In some embodiments, the techniques described herein relate to a tip, wherein the tip is disposable.

[0030] In some embodiments, the techniques described herein relate to a tip, wherein the skin treatment device includes a handpiece or other handheld device.

[0031] In some embodiments, the techniques described herein relate to a tip for a skin treatment device, the tip including: a peripheral member located along a distal end of the tip, wherein the peripheral member is configured to contact a skin surface when the tip is secured to an end of the skin treatment device; at least one interior member at least partially positioned within an interior area or region defined by the peripheral member; wherein the peripheral member has a flexibility that is greater than a flexibility of the at least one interior member; and at least one fluid delivery port or opening in fluid communication with the interior area or region, the at least one fluid delivery port or opening configured to direct a treatment material to the interior area or region during use.

[0032] In some embodiments, the techniques described herein relate to a skin treatment system, wherein the skin treatment system includes a skin treatment handpiece and a tip.

[0033] In some embodiments, the techniques described herein relate to a skin treatment system, wherein the skin treatment system includes a microdermabrasion system.

[0034] In some embodiments, the techniques described herein relate to a skin treatment system, the system including: a handpiece configured to be grasped and manipulated by a user; and a tip, wherein the tip is configured to be removably secured to a distal end of the handpiece.

[0035] In some embodiments, the techniques described herein relate to a skin treatment system, the system including: a handpiece configured to be grasped and manipulated by a user; and a tip, wherein the tip is configured to be removably secured to a distal end of the handpiece.

[0036] In some embodiments, the techniques described herein relate to a system, further including: at least one treatment material source; and a vacuum source; wherein the system is configured to deliver at least one treatment material from the at least one treatment material source to the tip; and wherein the system is configured to transfer waste from the tip

EDGE.218WO -5- Knobbe, Martens, Olson & Bear, LLP to a waste container with assistance of a suction or vacuum generated along the tip hy the vacuum source.

[0037] In some embodiments, the techniques described herein relate to a system, wherein the at least one treatment material source includes a container configured to be secured to the handpiece.

[0038] In some embodiments, the techniques described herein relate to a system, wherein the at least one treatment material source includes a container configured to be secured to a manifold or other fluid distribution member of the system.

[0039] In some embodiments, the techniques described herein relate to a skin treatment system, the system including: a handpiece configured to be grasped and manipulated by a user; and a tip for a skin treatment device, the tip including: a peripheral member located along a distal end of the tip, wherein the peripheral member is configured to contact a skin surface when the tip is secured to an end of the skin treatment device; at least one interior member at least partially positioned within an interior area or region defined by the peripheral member; wherein the peripheral member has a flexibility that is greater than a flexibility of the at least one interior member; and at least one fluid delivery port or opening in fluid communication with the interior area or region, the at least one fluid delivery port or opening configured to direct a treatment material to the interior area or region during use.

[0040] In some embodiments, the techniques described herein relate to a system, further including: at least one treatment material source; and a vacuum source; wherein the system is configured to deliver at least one treatment material from the at least one treatment material source to the tip; and wherein the system is configured to transfer waste from the tip to a waste container with assistance of a suction or vacuum generated along the tip by the vacuum source.

[0041] In some embodiments, the techniques described herein relate to a system, wherein the at least one treatment material source includes a container configured to be secured to the handpiece.

[0042] In some embodiments, the techniques described herein relate to a system, wherein the at least one treatment material source includes a container configured to be secured to a manifold system of the system.

EDGE.218WO -6- Knobbe, Martens, Olson & Bear, LLP [0043] In some embodiments, the techniques described herein relate to a method for treating skin, the method including: positioning a distal end of a skin treatment device along a targeted skin surface; wherein the skin treatment device includes a handpiece configured to be grasped and manipulated by a user; wherein the skin treatment device further includes a tip secured to the handpiece; wherein the tip includes a peripheral member located along a distal end of the tip, wherein the peripheral member is configured to contact the targeted skin surface during use; wherein at least one interior member is at least partially positioned within an interior area or region defined by the peripheral member; wherein the peripheral member has a flexibility that is greater than a flexibility of the at least one interior member; and wherein the skin treatment device is configured to deliver a treatment material to the interior area or region of the tip during use; and moving the skin treatment device along the targeted skin surface to perform a desired skin treatment.

[0044] In some embodiments, the techniques described herein relate to a method: further including generating a vacuum or suction force along the interior area or region, wherein generating the vacuum or suction force along the interior area or region includes activating a vacuum source that is in fluid communication with the handpiece; wherein contacting the skin surface includes at least partially deforming the peripheral member so that the peripheral member at least partially conforms to the targeted skin surface; wherein a durometer of the peripheral member is lower than a durometer of the at least one interior member or feature; and wherein the at least one interior member includes at least one protruding member.

[0045] In some embodiments, the techniques described herein relate to a method, further including generating a vacuum or suction force along the interior area or region.

[0046] In some embodiments, the techniques described herein relate to a method, wherein generating the vacuum or suction force along the interior area or region includes activating a vacuum source that is in fluid communication with the handpiece.

[0047] In some embodiments, the techniques described herein relate to a method, wherein the vacuum source includes a vacuum pump.

[0048] In some embodiments, the techniques described herein relate to a method, wherein positioning the distal end of the skin treatment device along the targeted skin surface includes contacting the skin surface with the peripheral member of the tip.

EDGE.218WO -7- Knobbe, Martens, Olson & Bear, LLP [0049] In some embodiments, the techniques described herein relate to a method, wherein contacting the skin surface includes at least partially deforming the peripheral member so that the peripheral member at least partially conforms to the targeted skin surface.

[0050] In some embodiments, the techniques described herein relate to a method, wherein a durometer of the peripheral member is lower than a durometer of the at least one interior member or feature.

[0051] In some embodiments, the techniques described herein relate to a method, wherein the at least one interior member includes at least one protruding member.

[0052] In some embodiments, the techniques described herein relate to a method, wherein the at least one interior member includes a member having a spiral or curved shape.

[0053] In some embodiments, the techniques described herein relate to a method, wherein each of the peripheral member and the at least one interior member is at least partially flexible or includes a flexible configuration.

[0054] In some embodiments, the techniques described herein relate to a method, wherein the peripheral member includes at least one elastomeric or other flexible polymeric material.

[0055] In some embodiments, the techniques described herein relate to a method, wherein at least a portion of the at least one interior member includes an abrasive material or feature.

[0056] In some embodiments, the techniques described herein relate to a method, wherein the abrasive material or feature is positioned along a distal surface of the at least one interior member.

[0057] In some embodiments, the techniques described herein relate to a method, wherein the abrasive material or feature is impregnated or otherwise embedded within at least a portion of the at least one interior member.

[0058] In some embodiments, the techniques described herein relate to a method, wherein the peripheral member extends more distally relative to a distal-most end of the at least one interior member.

[0059] In some embodiments, the techniques described herein relate to a method, wherein the at least one interior member extends to or substantially to a distal end of the peripheral member.

EDGE.218WO -8- Knobbe, Martens, Olson & Bear, LLP [0060] In some embodiments, the techniques described herein relate to a method, wherein at least a portion of the at least one interior member is configured to abrade or exfoliate skin tissue when the tip is moved relative to said skin tissue during use.

[0061] In some embodiments, the techniques described herein relate to a method, wherein at least a portion of the at least one interior member is not configured to abrade or exfoliate skin tissue when the tip is moved relative to said skin tissue during use.

[0062] In some embodiments, the techniques described herein relate to a method, wherein at least a portion of the at least one interior member includes at least one knub or other member or feature configured to provide a massaging effect on skin tissue being treated during use.

[0063] In some embodiments, the techniques described herein relate to a tip configured to be secured to a distal end of a handpiece of a skin treatment system, the tip including: a distal portion configured to contact skin and a proximal portion configured to secure to a handpiece; a peripheral lip extending to the distal end, the peripheral lip defining an interior area; at least one fluid delivery opening located within the interior area and configured to deliver a treatment fluid to the interior area during use; at least one waste opening located within the interior area and configured to remove spent fluid and other debris from the interior area during use; and at least one protrusion positioned within the interior area and extending distally to or near the distal end with a first protrusion height; wherein the peripheral lip has a peripheral lip durometer and the at least one protrusion has a protrusion durometer, the peripheral lip durometer being greater than the protrusion durometer; wherein the at least one protrusion creates a fluid flow pathway from the at least one fluid delivery opening(s) to the at least one waste opening(s) along the interior area during use; and wherein the spent fluid and other debris is removed from the tip via the at least one waste opening and the handpiece.

[0064] In some embodiments, the techniques described herein relate to a tip, wherein the spent fluid and other debris received through the at least one waste opening accumulate in a waste collection region which is in fluid connection with the handpiece.

[0065] In some embodiments, the techniques described herein relate to a tip, wherein the waste collection region is annular or substantially annular.

EDGE.218WO -9- Knobbe, Martens, Olson & Bear, LLP [0066] In some embodiments, the techniques described herein relate to a tip, wherein a height of the peripheral lip is larger than a height than any of the at least one protrusion.

[0067] In some embodiments, the techniques described herein relate to a tip, wherein a height of the at least one protrusion varies.

[0068] In some embodiments, the techniques described herein relate to a tip, wherein a height of the at least one protrusion increases as the protrusion approaches the peripheral lip.

[0069] In some embodiments, the techniques described herein relate to a tip, wherein the peripheral lip durometer is lower than the durometer of at least one protrusion.

[0070] In some embodiments, the techniques described herein relate to a tip, wherein a surface of at least one of the peripheral lip or the at least one protrusion which could contact skin additionally includes an abrasive feature.

[0071] In some embodiments, the techniques described herein relate to a tip, wherein the abrasive feature is selected from the group including: a ribbed surface, a pored surface, an abrasive material, an abrasive chemical composition, and a surface with sharp or abrasive features.

[0072] In some embodiments, the techniques described herein relate to a tip, wherein the abrasive feature includes a plurality of abrasive features.

[0073] In some embodiments, the techniques described herein relate to a tip, wherein a distal most surface of the at least one protrusion is not parallel with a plane defined by a distal most surface of the peripheral lip.

[0074] In some embodiments, the techniques described herein relate to a tip, wherein the tip further includes an at least second protrusion.

[0075] In some embodiments, the techniques described herein relate to a tip, wherein the at least second protrusion has a second protrusion height measured distally from the interior area.

[0076] In some embodiments, the techniques described herein relate to a tip, wherein the second protrusion height is different than the first protrusion height.

EDGE.218WO -10- Knobbe, Martens, Olson & Bear, LLP [0077] In some embodiments, the techniques described herein relate to a tip, wherein the second protrusion height is the same or substantially the same as the first protrusion height.

[0078] In some embodiments, the techniques described herein relate to a tip, wherein the tip includes one or more rigid or semi-rigid materials.

[0079] In some embodiments, the techniques described herein relate to a tip, wherein the tip includes at least one plastic material.

[0080] In some embodiments, the techniques described herein relate to a tip, wherein the tip includes at least one metal or alloy.

[0081] In some embodiments, the techniques described herein relate to a tip, wherein the tip is disposable.

[0082] In some embodiments, the techniques described herein relate to a tip, wherein the tip is reusable.

[0083] In some embodiments, the techniques described herein relate to a tip, wherein the tip is manufactured or otherwise produced as a unitary or monolithic item.

[0084] In some embodiments, the techniques described herein relate to a tip, wherein a plane along a distal face of the distal portion of the tip is angled relative to a longitudinal axis of the tip and relative to an axis perpendicular to the longitudinal axis.

[0085] In some embodiments, the techniques described herein relate to a tip, wherein an angle of the tip relative to the axis perpendicular to the longitudinal axis is 10 to 30 degrees.

[0086] In some embodiments, the techniques described herein relate to a tip, wherein the tip is configured to be used on a torso of a subject.

[0087] In some embodiments, the techniques described herein relate to a tip, wherein the tip is configured to be used on a lip of a subject.

[0088] In some embodiments, the techniques described herein relate to a tip, wherein the tip is configured to be used on a scalp of a subject.

[0089] In some embodiments, the techniques described herein relate to a tip, wherein the tip includes at least two separable parts configured to secure to one another along an interface point.

EDGE.218WO -11- Knobbe, Martens, Olson & Bear, LLP [0090] In some embodiments, the techniques described herein relate to a tip, wherein the at least one protrusion is selected from the group including: a raised opening, a distally extended protrusion, a partitioned cell, a flow director or diverter, an internal wall or baffle, an internal bowl or other recess, a bar, a stem, and another protruding and/or recessed member or feature.

[0091] In some embodiments, the techniques described herein relate to a tip configured to be secured to a distal end of a handpiece of a skin treatment system, the tip including: a distal portion configured to contact skin and a proximal portion configured to secure to a handpiece; a peripheral lip extending to the distal end, the peripheral lip defining an interior area; and at least one protrusion positioned within the interior area and extending distally to or near the distal end with a first protrusion height; wherein the at least one protrusion creates a fluid flow pathway from the at least one fluid delivery opening(s) to the at least one waste opening(s) along the interior area during use.

[0092] Disclosed herein are tips configured for use to treat the skin of a subject. The tips can be configured to be used with a treatment device to apply a treatment fluid to the skin. The tips can form a partial or temporary seal against the skin of a subject and dragged along the skin to perform a treatment on the skin. The tips can be outfitted with abrasive features which can assist in a chosen treatment on the skin. Variations on characteristics of the tips can make a tip more suited for specific treatments.

Brief Description of the Drawings

[0093] These and other features, aspects and advantages of the present application are described with reference to drawings of certain embodiments, which are intended to illustrate, but not to limit, the present inventions. It is to be understood that these drawings are for the purpose of illustrating the various concepts disclosed herein and may not be to scale.

[0094] FIG. 1A illustrates a perspective view of a possible handpiece configured for use in a skin treatment system;

[0095] FIG. IB illustrates a side view of the handpiece of FIG. 1A;

[0096] FIG. 2A illustrates a perspective view of a tip configured for use in a skin treatment system, according to one embodiment;

EDGE.218WO -12- Knobbe, Martens, Olson & Bear, LLP [0097] FIG. 2B illustrates a diagrammatic side view of a tip configured for use in a skin treatment system, according to one embodiment;

[0098] FIG. 2C illustrates a diagrammatic side view of a tip configured for use in a skin treatment system, according to one embodiment;

[0099] FIG. 2D illustrates a diagrammatic side view of a tip configured for use in a skin treatment system, according to one embodiment;

[0100] FIG. 3 illustrates a diagrammatic side view of a tip configured for use in a skin treatment system, according to one embodiment;

[0101] FIG. 4A schematically illustrates a cross-sectional view of a tip configured for use in a skin treatment system, according to one embodiment;

[0102] FIG. 4B schematically illustrates a perspective view of a tip configured for use in a skin treatment system, according to one embodiment;

[0103] FIG. 5 illustrates an annotated diagrammatic front view of a tip configured for use in a skin treatment system, according to one embodiment;

[0104] FIGS. 6A and 6B illustrate side views of a tip configured for use in a skin treatment system, according to one embodiment;

[0105] FIG. 7 illustrates a diagrammatic side view of the tip of FIG. 2B, extended to show more of the tip and its interface with a skin treatment system;

[0106] FIG. 8A illustrates a perspective view of another embodiment of a tip configured for use in a skin treatment system, comprised of two pieces;

[0107] FIG. 8B illustrates a perspective view of the embodiment of a tip configured for use in a skin treatment system of FIG. 8A, where the two pieces are separated;

[0108] FIG. 8C illustrates a diagrammatic side view of a cross section of the embodiment of a tip configured for use in a skin treatment system of FIG. 8A;

[0109] FIG. 8D illustrates a perspective view of the embodiment of a tip configured for use in a skin treatment system of FIG. 8A;

[0110] FIG. 8E illustrates a diagrammatic view of the expected fluid flow pathways for the embodiment of a tip configured for use in a skin treatment system of FIG. 8A;

[0111] FIG. 9A illustrates a perspective view of another embodiment of a tip and adaptor configured for use in a skin treatment system, where the tip is shown as a cross-section;

EDGE.218WO -13- Knobbe, Martens, Olson & Bear, LLP [0112] FIG. 9B illustrates a perspective view of the tip and adaptor configured for use in a skin treatment system of FIG. 9A;

[0113] FIG. 9C illustrates a diagrammatic side view cross-section of the tip and adaptor configured for use in a skin treatment system of FIG. 9A;

[0114] FIG. 9D illustrates a perspective view of the tip configured for use in a skin treatment system of FIG. 9A without its adaptor;

[0115] FIG. 9E illustrates a perspective view of the adaptor configured for use in a skin treatment system of FIG. 9A without its tip;

[0116] FIG. 10A illustrates a diagrammatic side view of a tip configured for use in a skin treatment system, according to one embodiment;

[0117] FIG. 10B illustrates a portion of a diagrammatic cross-section of the tip of FIG. 10A;

[0118] FIG. 11 A illustrates a perspective view of a tip configured for use in a skin treatment system, according to one embodiment;

[0119] FIG. 11B illustrates another view of the tip configured for use in a skin treatment system of FIG. 11 A;

[0120] FIG. 11C illustrates a diagrammatic side view cross-section of the tip configured for use in a skin treatment system of FIG. 11 A;

[0121] FIG. 11D illustrates a diagrammatic view of the expected fluid flow pathways for the embodiment of a tip configured for use in a skin treatment system of FIG. HA;

[0122] FIG. 12A illustrates a perspective view of a tip configured for use in a skin treatment system, according to one embodiment;

[0123] FIG. 12B illustrates another view of the tip configured for use in a skin treatment system of FIG. 12A;

[0124] FIG. 12C illustrates a diagrammatic side view cross-section of the tip configured for use in a skin treatment system of FIG. 12A;

[0125] FIG. 12D illustrates a diagrammatic view of the expected fluid flow pathways for the embodiment of a tip configured for use in a skin treatment system of FIG. 12A;

EDGE.218WO -14- Knobbe, Martens, Olson & Bear, LLP [0126] FIG. 13A illustrates a perspective view of a tip configured for use in a skin treatment system, according to one embodiment;

[0127] FIG. 13B illustrates another view of the tip configured for use in a skin treatment system of FIG. 13 A;

[0128] FIG. 13C illustrates a diagrammatic side view cross-section of the tip configured for use in a skin treatment system of FIG. 13A;

[0129] FIG. 13D illustrates a diagrammatic view of the expected fluid flow pathways for the embodiment of a tip configured for use in a skin treatment system of FIG. 13 A;

[0130] FIG. 14A illustrates a perspective view of a tip configured for use in a skin treatment system, according to one embodiment;

[0131] FIG. 14B illustrates another view of the tip configured for use in a skin treatment system of FIG. 14A;

[0132] FIG. 14C illustrates a diagrammatic side view cross-section of the tip configured for use in a skin treatment system of FIG. 14A;

[0133] FIG. 14D illustrates a diagrammatic view of the expected fluid flow pathways for the embodiment of a tip configured for use in a skin treatment system of FIG. 14A;

[0134] FIG. 15A illustrates a diagrammatic cross-sectional view of a tip configured for use in a skin treatment system, according to one embodiment;

[0135] FIG. 15B illustrates a diagrammatic cross-sectional view of a tip configured for use in a skin treatment system of FIG. 15 A;

[0136] FIG. 16A illustrates a perspective view of a tip assembly configured for use in a skin treatment system, according to one embodiment;

[0137] FIG. 16B illustrates another perspective view of the tip assembly configured for use in a skin treatment system, according to one embodiment of FIG. 16 A, where the tip is separated from its adaptor collar’;

[0138] FIG. 16C illustrates a diagrammatic side view cross-section of the tip configured for use in a skin treatment system of FIG. 16A;

[0139] FIG. 17 illustrates a perspective view of a tip assembly configured for use in a skin treatment system, according to one embodiment;

EDGE.218WO -15- Knobbe, Martens, Olson & Bear, LLP [0140] FIG. 18 illustrates a perspective view of a tip configured for use in a skin treatment system, according to one embodiment;

[0141] FIG. 19A illustrates a perspective view of a tip configured for use in a skin treatment system, according to one embodiment;

[0142] FIG. 19B illustrates a perspective view of a tip configured for use in a skin treatment system, according to one embodiment; and,

[0143] FIG. 20 illustrates a diagrammatic cross-sectional view of a tip configured for use in a skin treatment system.

Detailed Description

[0144] Although the various embodiments disclosed herein have specific relevance to skin treatment generally, and skin treatment systems, devices and related methods more specifically, the features, advantages and other characteristics disclosed herein may have direct or indirect applicability in other applications, such as, for example, medical devices, other devices and systems for the treatment or benefit of humans and/or animals, industrial applications, other mechanical devices and/or the like.

[0145] The hydrodermabrasion process typically employs the use of rigid (e.g., plastic, metal, etc.) tips for treatment and exfoliation of skin in resilient areas of the face and body. In these cases, rigid tips often pose challenges with respect to vacuum occlusion, skin sensitivity, and overall sensitivity to bony areas such as the scalp and brow.

[0146] Several embodiments disclosed herein are particularly advantageous because they include one, several, or all of the following benefits: provide for enhanced delivery of treatment fluids to the skin of a subject; provide a larger surface area for a skin treatment tip that can help with the treatment of certain anatomical portions (e.g., a person’s back or torso, other larger areas, relatively bony portions, etc.); achieve better exfoliation/extraction and nourishment performance (e.g., using treatment fluids); create more even distribution of serums and/or other treatment fluids/materials to larger coverage areas for both exfoliation and extraction at in a faster manner; and facilitating a user to exert forces to a skin surface (e.g., especially a “bony” skin surface) and/or the like.

[0147] FIGS. 1A and IB illustrate one embodiment of a handpiece or handheld device 10 configured to be grasped, manipulated, or otherwise used for a skin treatment system.

EDGE.218WO -16- Knobbe, Martens, Olson & Bear, LLP In some embodiments, the handpiece 10 is part of a larger skin treatment system, such as, for example, a system that includes a tower or console (not shown). Such a tower or console can comprise a manifold assembly for receiving one or more (e.g., 1, 2, 3, 4, more than 4, etc.) bottles or other containers of treatment fluids to be used in a skin treatment procedure. The tower assembly can further include one or more waste canisters or other containers that are configured to receive spent fluids, exfoliated, or otherwise removed skin tissue and/or other waste products resulting from a skin treatment procedure. In some arrangements, one or more of the bottles, canisters or other containers that are designed and otherwise adapted to be secured to the tower assembly can be replaceable, interchangeable and/or otherwise removable (e.g., for emptying, autoclaving or other types of cleaning, replacement, etc.).

[0148] In embodiments of a skin treatment system that include tower assembly or console, such tower assembly or console comprise (and/or can be configured to communicate or work with) one or more input and/or output devices (e.g., a touchscreen or other monitor, a keyboard, other controllers, etc.), an outer housing or other exterior structure, tubing, one or more trays or other storage components, casters, wheels or other moving members or components, interior components (e.g., processor, memory, power source, sensors, tubing, valves and/or other hydraulic components, electrical wiring and other electrical components, etc.) and/or the like. In some embodiments, a tower system or console comprises a vacuum or suction source that is configured to couple to a handpiece 10.

[0149] A skin treatment system can be configured to permit a user (e.g., an aesthetician, a cosmetician, a dermatologist, etc.) to connect a handpiece 10 to a manifold assembly as noted herein (e.g., using a “dummy” cartridge 34, a luer or other connector 30, a fluid conduit extending from the luer 30 to a manifold system of a tower assembly, etc.), and/to insert an actual fluid or treatment material-containing cartridge, such as, e.g., a vial, (not shown) directly into the handpiece 10, e.g., a recess 36 of the handpiece assembly. These two options can be used interchangeably to perform a treatment procedure or protocol, as desired or required.

[0150] Irrespective of if a vacuum or suction source is included as part of the skin treatment system and/or its various components (e.g., tower assembly, handpiece, etc.) or provided separate of the skin treatment system, the handpiece 10 can include one or more

EDGE.218WO -17- Knobbe, Martens, Olson & Bear, LLP vacuum or suction ports or connectors 40. As shown in FIGS. 1 A and 1 B, such a vacuum port or connector 40 can be located along a proximal end 14 of the handpiece 10.

[0151] According to some embodiments, once a handpiece 10 is coupled to a vacuum source (e.g., via a vacuum port 40, a vacuum or suction conduit (not shown), etc.) and if the vacuum source (i.e., a vacuum pump, etc.) is activated, the vacuum source generates suction (e.g., a negative pressure relative to atmospheric or ambient pressure) along the distal end 12 of the handpiece 10. In some arrangements, such a suction or vacuum force along the tip or distal end of a handpiece can help draw or deliver one or more treatment fluids to the distal end 12 (e.g., via a manifold assembly of a tower or console (not shown), via a vial or cartridge positioned directly within the handpiece 10, etc.). In some embodiments, the distal end 12 of the handpiece 10 is shaped, sized and/or otherwise configured to receive a tip, such as the tip 100 illustrated in FIGS. 2A to 2B, any other tip disclosed herein and/or equivalents or modifications thereof.

[0152] With further reference to FIGS. 1A and IB, the distal end 12 of the handpiece can include at least one fluid delivery port or opening 22 and/or at least one vacuum port or opening 24. In some embodiments, the fluid delivery port or opening 22 is configured to be placed in fluid communication with a fluid source (e.g., a manifold system and bottles secured thereto, a vial or fluid container positioned directly into a recess or opening 36 of the handpiece 10, etc.). Such fluid communication can be facilitated by one or more conduits, channels or other passages that are internal or external to the handpiece.

[0153] Likewise, in some embodiments, the vacuum port or opening 22 is configured to be placed in fluid communication with a vacuum or suction source (e.g., in a tower or console of a skin treatment system, in the handpiece 10, included in another portion or component of the skin treatments system, separate of the skin treatment system, etc.). Such fluid communication can be facilitated by one or more conduits, channels or other passages that are internal or external to the handpiece.

[0154] As will be discussed in connection with one or more tip embodiments disclosed herein, the tip can be configured to form a seal (at least a temporary one) with the skin surface being treated when the tip is positioned in a specific manner relative to such skin surface. For example, the tip can include a peripheral lip or other outer member 132 (see, e.g., FIG. 2A) that is configured to contact skin tissue during use of the handpiece. Such a lip or

EDGE.218WO -18- Knobbe, Martens, Olson & Bear, LLP other peripheral member 132 can be configured to form at least a partial seal with skin and help generate a vacuum or suction force within an interior area circumscribed by the lip or member when the handpiece is coupled to a vacuum source and such vacuum source is activated. In turn, according to some arrangements, the vacuum or suction force along such an interior area along the tip or distal end can help draw or otherwise transfer fluids and/or other treatment materials from one or more sources to the tip or distal end (e.g., using the suction or vacuum alone without the need for positive pressure exerted on the fluids or other treatment materials being transferred to the tip or distal end). Thus, in such arrangements, treatment fluids and/or other materials from vials, bottles, other containers and/or other fluid source are “pulled” or moved to the handpiece 10 to the distal end 12 (and any tip secured thereto) using suction created along the distal end of the handpiece 10.

[0155] In other embodiments, treatment fluids and/or other materials can be transferred to the handpiece assembly 10 from the manifold assembly using the application of positive pressure within or along the main fluid conduit and/or the bottles or other containers secured to the manifold assembly. This can be accomplished either in lieu of or in addition to the generation of suction along the handpiece assembly 10 (e.g., as discussed herein, such as, for instance, with reference to the arrangement illustrated in FIG. 5).

[0156] Fluids and/or other treatment materials from two or more bottles or other containers secured to a manifold assembly can be delivered to the handpiece assembly 10 sequentially or simultaneously, as desired or required. As discussed, the fluid network of the system can include one or more valves, other flow control devices or member, flow meters and/or the like to help regulate the flow of fluids and/or other materials from a fluid source (e.g., a manifold assembly, a vial or cartridge, etc.) to the tip 12 or distal end 14 of a handpiece.

[0157] According to some embodiments, the system is configured to deliver treatment fluid from a fluid source (e.g., a vial or other container secured to the handpiece, one or more bottles coupled to a manifold, etc.) continuously. However, in other embodiments, treatment fluid(s) can be provided using a pulsed pattern or non-continuously. In some arrangements, a pulsed pattern can be created by selectively actuating one or more valves and/or other hydraulic features or components of the handpiece and/or any other portion of a skin treatment system (e.g., modulating the vacuum pump or other suction device in fluid communication with the skin treatment system).

EDGE.218WO -19- Knobbe, Martens, Olson & Bear, LLP [0158] According to some embodiments, the handpiece 10 includes a lever or other controller 50 (e.g., switch, button, roller, other mechanical, electrical and/or electromechanical device or component) for adjusting the flow of treatment fluids and/or materials to the distal end 12 of the handpiece. A tip can be removably secured to the distal end 12 of the handpiece. Additional information regarding one or more embodiments of tips that may be secured to the distal end 12 of a handpiece 10 such tips is provided below.

[0159] The tips illustrated and discussed herein, and/or equivalents thereof, can be configured to secure to one or more other types of handpieces and/or other modalities (e.g., besides the handpiece illustrated in FIGS. 1A and IB herein). For example, the tip can be secured to a larger or smaller handpiece, such as, for example, a lymphatic handpiece, a handpiece intended for body treatments or other larger area treatments and/or the like. In some embodiments, the tips are configured to connect to the handpiece by a friction fit or press fit connection, e.g., connecting a proximal portion of the tip to a distal end 12 of the handpiece 10.

[0160] With continued reference to FIGS. 1A and IB, a cartridge 34, regardless of whether it is a cartridge that comprises fluid or other treatment material within an interior chamber or whether it is a “dummy” cartridge 34 that places the handpiece in fluid communication with a manifold or other fluid source or network, is configured to be removably positioned within a recess 36 of the handpiece 10. In some embodiments, the recess 36 comprises an open recess that is accessible along the exterior of the handpiece assembly. In some arrangements, the recess 36 is easily accessible from the exterior of the handpiece assembly to permit a user to insert and remove a cartridge 34 within/out of the recess 36 without manipulating any portion of the handpiece 10 (e.g., without opening an interior of the handpiece, without taking any additional steps, etc.), as desired or required. In some configurations, the recess 36 is located along the proximal end of the handpiece 10 and faces in an opposite or substantially opposite direction than the distal end 12 (and any tip secured along the distal end 12) of the handpiece 10.

[0161] For any of the skin treatment system embodiments disclosed herein, a cartridge 34 can be configured to be selectively locked and unlocked to the handpiece 10. In some arrangements, the cartridge 34 can be locked and unlocked using a rotation, twisting, pushing, sliding and/or other movement of the cartridge relative to the handpiece once the

EDGE.218WO -20- Knobbe, Martens, Olson & Bear, LLP cartridge is secured to the handpiece. According to some embodiments, the cartridge 34 is configured to lock to the main body portion of the handpiece using one or more devices or methods, such as, for example, locking tabs, clasps, magnetic connectors, other fasteners and/or the like.

[0162] As noted above, in some embodiments, the “dummy” cartridge 34 of FIGS. 1A and IB can be replaced with a fluid and/or other treatment material vial or cartridge. Such a vial or other container can include one or more chambers that contain a serum and/or other treatment fluid or material. In such embodiments, the vacuum or suction force generated along the tip or distal end of the handpiece can help draw or transfer serums and/or other treatment fluids/materials stored within the vial or other container to the tip or distal end 12 when the tip or distal is positioned along the targeted skin surface.

[0163] In some embodiments, both a “dummy” cartridge 34 that is in fluid communication with a manifold (e.g., of a tower or console system) and a vial or cartridge that itself includes one or more serums or fluids, e.g., a booster vial can together be used in a particular system and/or procedure. Therefore, in some arrangements, the user can swap cartridges and/or other containers 34 during and/or between treatment steps or procedures, as desired or required.

[0164] As noted above, a handpiece 10 can be used with one or a variety of skin treatment tips that can be removably and/or replaceably positioned along a distal end of handpiece. At least some embodiments of such tips are described and/or illustrated herein. See, for example and without limitation, tips 100, 800, 900, 1100, 1200, 1300, 1400, 1500, 1600, 1700. A tip can include any tips disclosed in U.S. Patent No. 8,048,089, filed as U.S. Pat. Appl. No. 11,392,348 on March 29, 2006 and issued on November 1, 2011, the entirety of which is hereby incorporated herein and made a part of this specification. See, for example, Figures 5A to HE and the corresponding disclosure, in U.S. Pat. No. 8,048,089, and U.S. Patent Application No. 09/699,220, filed on October 27, 2000 and issued on October 7, 2003 as U.S. Patent No. 6,629,983, the entireties of both of which are hereby incorporated by reference herein.

[0165] As depicted in FIGS. 2A to 2D, the tip 100 can include one or more internal features 140 that form or include a desired pattern along the region near the distal end of the tip that is defined by a peripheral lip or other outer member 132. Such internal features 140

EDGE.218WO -21- Knobbe, Martens, Olson & Bear, LLP (e.g., protrusions, other features or members extending outwardly or distally, recesses, baffles, internal walls, etc.) can provide one or more functions. Such functions can include, by way of example and without limitation: abrading or exfoliating skin tissue as the tip 100 is moved relative to skin tissue being treated (e.g., translated or otherwise moved along or relative to a skin surface, against the skin, on the skin surface, etc.); creating a desired flow pattern of any treatment fluids being delivered to the tip from a fluid source (e.g., a vial, a manifold system, etc.); massaging or otherwise manipulating the skin tissue; assisting in directing a treatment fluid further into a skin surface and/or the like. The tip 100 can include one or more fluid inlet ports 150. Such fluid inlet ports 150 can be located at, along, or near the center of the tip. However, in other embodiments, the fluid inlet port(s) 150 is/are located at any other location of the tip, either in lieu of or in addition to the center, as desired or required. Regardless of the exact quantity, size, location, orientation and/or other details related to the fluid delivery port(s) or opening(s), such port(s) or opening(s) can be in fluid communication with one or more openings 122 (e.g., opening defined and/or created by the stem 120) that extend to or along a proximal portion 110 of the tip. Thus, once the tip 100 is secured to the distal end 12 of the handpiece 10, such proximal opening(s) can be placed in fluid communication with one or more fluid delivery ports, opening, conduits, passages and/or the like of the handpiece 10.

[0166] In some embodiments, any of the tips disclosed herein or equivalents or related versions thereof can include two or more portions with varying flexibility or rigidity. For example and without limitation, the tip can include a first or an outer or peripheral member (e.g., peripheral lip, peripheral edge, lip, outer member, circumscribing member, interior-area defining member, or edge) that is softer or more flexible (e.g., less rigid, having a lower durometer) than a second or an interior portion or member of the tip. In some arrangements, the softer or more flexible peripheral lip or other outer member defines an interior area or region within which the more rigid or less flexible interior portion or member of the tip is positioned. In some embodiments, the interior area or region comprises one or more protruding members or features that are configured to at least partially abrade or exfoliate skin tissue (e.g., when the tip is translated, advanced, or moved relative to skin tissue). In some embodiments, the interior region or portion (e.g., the interior protruding members or features) are configured to abrade or exfoliate skin more efficiently than the peripheral lip or other outer member.

EDGE.218WO -22- Knobbe, Martens, Olson & Bear, LLP [0167] A tip or other distal portion in a skin treatment device or system having a more flexible first (c.g., outer or peripheral) portion and a less flexible (more rigid) second (e.g., interior) portion or member can provide certain benefits and advantages. For example, the softer or more flexible outer or peripheral portion (e.g., peripheral lip or outer member) can more easily conform to the skin surface being treated. In some embodiments, the outer or peripheral portion can conform to create a better or more enhanced seal with the skin surface. Such a feature can be beneficial in systems that rely on the generation of a suction or vacuum force along an interior defined by the outer or peripheral portion to help pull or transfer treatment fluids and/or other materials to the surface (e.g., from a bottle, cartridge, vial and/or other fluid source). The inclusion of a harder (e.g., less flexible, more rigid, etc.) interior member (e.g., a protruding member(s) or feature(s)) can help with the abrasion or exfoliation of the skin surface as the handpiece or other device to which the tip or distal end is positioned is moved (e.g., translated relative to the skin surface).

[0168] In some embodiments, the outer or peripheral lip or portion and the interior (e.g., more rigid) protruding or other exfoliating member(s) or feature(s) comprise elastomeric or polymeric material. Thus, the outer or peripheral member(s) and the interior member(s) or feature(s) can include a flexible or semi-rigid construction or configuration. However, in other arrangements, the outer or peripheral member can include a flexible configuration while the interior member(s) or feature(s) can include a rigid or semi-rigid configuration, as desired or required.

[0169] According to some arrangements, both lower-durometer polymers and higher-durometer polymers are incorporated into a tip design. This can help provide additional benefits in treating skin areas with higher sensitivity or areas which contain features or contours (e.g., hair, eyebrows, other areas without defining bone structures such as the lips, etc.) where having a contact surface that includes a lower-durometer polymer would be beneficial in forming a temporary seal with the treatment area. The use of lower-durometer polymers can provide a beneficial resiliency for scalp and sensitive areas. However, certain features of the tip, including the mounting to the handpiece, may include a rigid and/or semirigid structure (e.g., to maintain a reliable fixation to adjacent portion(s) of the tip). As such, the tip 100 can have a multi-durometer construction, allowing the skin-contact areas to be molded using lower durometer polymers, while the tip-to-handpiece connection features are

EDGE.218WO -23- Knobbe, Martens, Olson & Bear, LLP molded using more rigid materials and/or construction. The combination of these dissimilar constructions or configurations (c.g., using different materials) can be achieved by various manufacturing methods (e.g., a two-shot molding process, insert molding, dual-durometer additive manufacturing, simple post-assembly of separate parts and/or the like), as desired or required.

[0170] Likewise, the tip can include one or more vacuum or suction ports or openings 154 along the distal portion 130 of the tip. As shown in FIGS. 2A to 2D, a tip can include at least one vacuum or suction port or opening 154. In the illustrated embodiment, the tip 100 comprises a total of one vacuum or suction port or opening 154. However, in other arrangements, the tip 100 can include more than one (e.g., 2, 3, 4, 5, 6, 7, 8, 9, 10, 10 to 15, more than 15, etc.) vacuum or suction port or opening 154, as desired or required.

[0171] As best illustrated by FIGS. 2B to 2D, the vacuum or suction ports or openings 154 can be fluidly coupled to each other (e.g., in fluid communication with one another) such that vacuum or suction is applied to all ports or openings 154 once the vacuum or suction source is activated. The vacuum or suction ports or openings 154 can extend below the distal portion 130 of the tip (e.g., the face or surface that defines the vacuum or suction ports 154) through a tip base surface 131 of the distal portion 130 of the tip 100 leading to an annular or other waste suction collection region 126. In some arrangements, spent fluids, exfoliated skin tissue, other debris and/or other materials that are transferred proximally from a treated skin surface and the area defined by the peripheral lip 132 through the vacuum or suction ports or openings 154 can accumulate or be collected in a waste suction collection region 126 (e.g., the annular region defined between an interior of the cylindrical portion 114 and the stem 120, see, for example, FIG. 6A and 6B). In some embodiments, such a waste suction collection region 126 is placed in fluid communication with one or more suction or vacuum ports or openings 24 (see, e.g., FIG. 1A) of the handpiece 10 to help remove any collected materials away from the tip 100 (e.g., toward a waste container using vacuum or suction that is applied to the handpiece).

[0172] For any of the embodiments disclosed herein or equivalents or related versions thereof, the tips can be disposable so that they are discarded and/or replaced during or after a treatment procedure (e.g., for hygienic and safety reason, as a result of the degradation of certain treatment features (e.g., the depletion of any abrading material or abrading

EDGE.218WO -24- Knobbe, Martens, Olson & Bear, LLP chemicals, exhaustion of an abrasive feature, etc.) and/or the like). However, in other arrangements, the tips, or portions of tips, can be configured (c.g., as result of its matcrial(s), such as, for example, stainless steel, other metals or alloys, other composites, etc., as result of its construction or design, etc.) to be reusable. Thus, in some arrangements, the tips are configured to withstand the temperature variations, chemicals and/or other conditions to which they may be subjected for cleaning, disinfecting, sterilization and/or the like. In some embodiments where the tip comprises a plurality of separate parts or portions that are configured to connect or secure (e.g., fixedly, removably, etc.) to one another using one or more securement devices, members, features, methods and/or the like, such as, for example and without limitation, mechanical, friction fit, press fit connections, or other temporary connection methods, only a portion of the tip may be designed to be reusable. For example and without limitation, a more rigid part of the tip may be designed to be reusable, whereas a less rigid part of the tip may be designed to be disposable.

[0173] The tips 100 can be manufactured as a single or unitary member. In other words, a tip 100 can include a unitary or monolithic construction, configuration or structure. Such a tip 100 can be manufactured using any suitable manufacturing method, such as, for example and without limitation, injection molding, other molding, additive manufacturing, thermosetting or forming technology and/or the like. The tips 100 can be at least partially (e.g., completely, partially, etc.) semi-rigid, flexible and/or elastic (e.g., having a varying durometer in one or more components and/or portions relative to another component or portion). In some arrangements, the tips comprise one or more thermoplastic materials (e.g., plastic, rubber, etc.). However, the tips 100 can include one or more other types of materials, either in addition to or in lieu of plastics, such as, for example, metals or alloys (e.g., stainless steel), other rubberized materials, other composites, manmade materials, natural materials and/or like, as desired or required. As noted, the tips 100 can be disposable or reusable. In some embodiments, the tips are manufactured using recyclable and/or reusable materials and/or using one or more green or environmentally advantageous methods or technologies.

[0174] With continued reference to the annotated view illustrated in FIG. 2A, the distal portion 130 of the tip 100 can include one or more features and/or members (e.g., protruding members, special surface features, recesses, etc.) 140 that extend distally and/or proximally (e.g., toward the distal end of the tip, and thus, toward the skin surface that will be

EDGE.218WO -25- Knobbe, Martens, Olson & Bear, LLP treated using the tip). Such features or members 140 can be included within an interior area or region defined by a peripheral lip or other outer member 132. As noted above, such interior features can be manufactured, produced, molded or otherwise formed together as a single, monolithic or unitary construction with other portions of the tip (e.g., a base portion of the tip from which the features or members extend). However, in other embodiments, such interior features 140 can be formed separately of other portions of the tip. For example, such internal face features 140 can be added and/or otherwise formed after the rest of the tip has been manufactured (e.g., by securing the features to the distal portion 130 of the tip, by removing material from and/or otherwise shaping or manipulating the distal portion 130 of the tip, etc.).

[0175] In some embodiments, the distance from the distal-most (e.g., furthest) surface of the peripheral lip or other outer member 132 to the base of the distal end of the tip 100 can be greater than the distance from the distal-most (e.g., furthest) surface of the at least one internal face feature or member 140 to the base (e.g., such that the peripheral lip 132 is more distal, or taller, than the internal face feature 140). In certain embodiments, this improves the seal (e.g., temporary seal) the peripheral lip 132 of the tip 100 makes with skin tissue. A more enhanced or better seal between the peripheral lip or other outer member 132 can help with maintaining a vacuum or suction force within an interior area circumscribed by the lip when the handpiece is coupled to a vacuum source and such vacuum source is activated. For instance, in some arrangements, having a more distal peripheral lip 132 relative to the at least one internal face feature or member 140 can reduce the likelihood that a resulting seal (e.g., partial and/or temporary seal) between the lip or other outer member and the skin of the subject is weakened or otherwise undermined (e.g., by interference created by the internal face feature 140 against the skin, by not creating a temporary seal between the lip or other outer member when the skin surface is highly contoured or non-smooth (e.g., by the presence of facial features, facial hair, etc.)). Thus, the likelihood of creating and maintaining a good or adequate seal (e.g., temporary seal) between the peripheral lip or other outer member or feature 132 and the skin surface being treated can be advantageously enhanced or improved using configurations such as those illustrated, discussed and/or otherwise disclosed herein.

[0176] According to some embodiments, the peripheral lip 132 can include a height (e.g., distance between base (or other portion of the tip) and the distal end) that is greater than the height (or equivalent dimension) of the internal face feature 140. This is demonstrated, for

EDGE.218WO -26- Knobbe, Martens, Olson & Bear, LLP example, in FTG. 2B, which shows a cross sectional view of the internal face feature 140 and peripheral lip 132 on the tip 100.

[0177] FIG. 2B illustrates the peripheral lip height 133 as well as interior or internal face feature height 141, second interior or internal face feature height 142, third interior or internal face feature height 143 and fourth interior or internal face feature height 144. In some arrangements, the peripheral lip height 133 is greater than the heights 141, 142, 143, 144 of all the interior face features. The interior or internal face features can include a similar height, shape, size and/or other properties than other interior features. However, in other embodiments, the height and/or other characteristics of the interior face features can vary relative to one another, as desired or required.

[0178] With continued reference to FIG. 2B, the interior or internal features or members 140 include a spiral or curved shape or design. For example, the illustrated embodiment comprises a spiral interior member or feature 140 having four or substantially four rotations or revolutions (e.g., about a central point or location) across the face of the tip 100. However, in other arrangements, the number of rotations a spiral internal member or feature 140 has across the face of the tip 100 can be different than four, such as, for example and without limitation, less than 1 (e.g., an incomplete rotation), 1, 1 to 2, 2, 2 to 3, 3, 3 to 5, 3 to 4, 4 to 5, 5, more than 5, etc., as desired or required. In some embodiments, a spiral internal member or feature 140 can make incomplete rotations across the face of the tip 100. The interior or internal face feature heights 141, 142, 143, 144 depicted in FIG. 2B are the same or substantially the same height. However, in other embodiments, the height of the at least one interior or internal face feature or member 140 may vary as the member along the interior area defined by the peripheral lip (e.g., as the interior feature or member moves radially outwards and approaches the peripheral lip 132). Peripheral lip height 133 and the internal face feature heights 141, 142, 143, 144 can be measured from a tip base surface 131 of the tip 100 to the midpoint of the furthest distal surface from the tip base surface 131 of the peripheral lip 132 or internal face feature 140. In some embodiments, peripheral member or lip height 133 and the internal face feature heights 141, 142, 143, 144 can also be measured from the tip base surface 131 to any other point on the peripheral lip 132 or the internal face features 140. In some embodiments, the interior or internal face feature heights 141, 142, 143, 144 vary as the internal face feature 140 moves (e.g., radially) from the center of the tip 100 toward the

EDGE.218WO -27- Knobbe, Martens, Olson & Bear, LLP peripheral lip 132. For example and without limitation, in embodiments where a spiral or other internal face feature 140 is located across the surface of the tip 100, the height of the internal face feature 140 can generally increase as the internal face feature 140 progresses radially outward, such that a singular internal face feature 140 can have various internal face feature heights as it progresses across base surface 131 of the tip 100.

[0179] According to some embodiments, the height or distal extent 133 of the peripheral lip or other outer member than defines an interior area or region is greater than the height or distal extent of each of the first interior or internal face feature height 141, the second interior or internal face feature height 142, the third interior or internal face feature height 143 and/or the fourth interior or internal face feature height 144. Thus, in some arrangements, the peripheral lip or other outer member 132 extends more distally than one, some or all of the interior features or members 140 (e.g., an interior member having a spiral shape or configuration, as illustrated in FIG. 2A), such that the peripheral lip 132 can contact a skin surface being treated before any of the internal face features 140 contact the surface of the skin.

[0180] In some embodiments, as illustrated in FIG 2B, the first interior or internal face feature height 141, the second interior or internal face feature height 142, the third interior or internal face feature height 143 and the fourth interior or internal face feature height 144 are the same height or substantially the same height. Therefore, the interior member or feature 140 can form a planar or substantially planar distal surface (e.g., albeit discontinuous). In some embodiments, as illustrated in FIGS. 2C and 2D, the interior or internal face feature 140 may have its greatest height in its section closest to the peripheral lip 132 (e.g., nearest the outer radial location of the feature or member 140, most radially outward from the center of the tip 100). In some embodiments, the height or distal extent of the member or feature 140 (e.g., a spiral member located along an interior area or region defined by a peripheral or outer lip or member 132) decreases from a first interior or internal face feature height or extent 141 to a second interior or internal face feature height or extent 142 to a third interior or internal face feature height or extent 143 to a fourth interior or internal face feature height or extent 144. The change in height or extent of the interior member 140 can be linear or non-linear (e.g., curved), as desired or required. In other arrangements, the interior feature or member 140 can have its greatest height or distal extent (e.g., relative to a base and/or the peripheral lip or other

EDGE.218WO -28- Knobbe, Martens, Olson & Bear, LLP outer member 132) along the radial center of the feature or member or along any other location of the feature or member, as desired or required.

[0181] In the embodiments where the distal-most surface of the interior or internal face features or members 140 and peripheral lip 132 are not parallel with the plane formed by the tip base surface 131 (e.g., as shown in FIG. 2D), the angle formed by the interior features or members (or portions thereof) can be decreased or increased (e.g., to accommodate different treatment surfaces or skin-types, to obtain a particular skin treatment effect or result, etc.), as desired or required. Non-planar or non-parallel shapes can be used for the peripheral lip or other outer member 132 and/or one or more portions of the interior or internal face features or members.

[0182] In some embodiments, as depicted in FIG. 2D, an angle 5 showing a slope or non-planar extent or shape of the peripheral lip or other outer member 132 and/or one or more portions of the interior face features or members (e.g., spiral-shaped protruding member) 140 is 5 to 40 degrees (e.g., 5 to 6, 6 to 7, 7 to 8, 8 to 9, 9 to 10, 10 to 11, 11 to 12, 12 to 13, 13 to 14, 14 to 15, 15 to 16, 16 to 17, 18 to 19, 19 to 20, 20 to 25, 25 to 30, 30 to 40 degrees, angles between the foregoing ranges and values, etc.). In other embodiments, the angle 8 is less than 5 degrees or greater than 40 degrees, as desired or required. In other embodiments, only the distal surface of the peripheral lip 132 is angled or non-planar (e.g., at an angle 8) relative to the tip base surface 131 of the tip 100, while the distal surfaces of the interior or internal face features 140 are parallel or substantially parallel to the tip base surface 131 of the tip 100.

[0183] For embodiments where the height(s) or distal extent(s) 141, 142, 143, 144 of the interior or internal face feature (or portions thereof) 140 vary as the feature 140 moves radially outwardly from a centerpoint or other central location of the feature to or near the peripheral lip 132 (e.g., radially outwardly), a change in height or distal extent can be accomplished by having the interior feature or member 140 include an increasing (e.g., gradually increasing) height or distal extent as the feature or member 140 moves from a central position radially outwardly toward the peripheral lip 132. One such embodiment is illustrated in FIG. 2C, which shows a cross sectional diagram of the interior feature or memberl40 and peripheral lip 132 on the tip 100. In alternative embodiments, the peripheral lip 132 and the interior features or member 140 can include a gradient (e.g., relative to a base, a plane

EDGE.218WO -29- Knobbe, Martens, Olson & Bear, LLP perpendicular or generally perpendicular to the handpiece to which the tip is attached, etc.) to create a desired non-planar shape or configuration. Thus, as depicted in FIG. 2D, the height of the interior member or feature can vary along the area or region defined by the peripheral lip or other outer member. In some arrangements, such an overall gradient can be accompanied by the interior member or feature and/or the peripheral lip having a localized slope (e.g., relative to a plane formed by a base or a plane generally perpendicular to the longitudinal axis of a handpiece to which the tip is attached) at one or more locations. In some embodiments with distinct internal face features 140, each internal face feature 140 can have a different height. In some embodiments, the height of each internal face feature 140 can be constant or substantially constant relative to the tip base surface 131. In some embodiments, the height of each internal face feature 140 can vary as it progresses across the base surface 131 of the tip 100, as desired or required.

[0184] In addition to or in lieu of varying the height or distal extent of the interior or internal face feature 140 (e.g., relative to the peripheral lip 132), the quality of the seal formed (e.g., temporarily, at least partially, etc.) between the tip 100 and the subject’s skin surface during a procedure may be improved by varying the configuration of the peripheral lip 132 and/or the interior features or members 140 of the tip. For example, as discussed in greater detail herein, the flexibility, stiffness and/or hardness of the lip or other outer member 132 and/or the interior feature(s) or member(s) can be strategically selected to maximize or increase/improve a flow pattern of fluid across the skin surface, permeability of the fluid into the skin surface, the seal formed against the skin surface, and/or other functionalities of the tip as desired or required.

[0185] As depicted in FIG. 3, the peripheral lip or other outer member 132 may comprise a configuration P (e.g., as a result of material(s) used, other physical properties, methods of manufacture or assembly, etc.) which has a flexibility, hardness, stiffness and/or other physical properties that is/are different that corresponding properties of the interior or internal member(s) or feature(s), or other portions of the tip. For example, both the peripheral lip or other outer member 132 and the interior member(s) or feature(s) 140 include a flexible or non-rigid configuration or construction. However, in some arrangements, the flexibility of the peripheral lip or other outer member can be different (e.g., greater or less) than the flexibility of one or more portions of the interior feature(s) or member(s), as desired or

EDGE.218WO -30- Knobbe, Martens, Olson & Bear, LLP required. The flexibility (or relatedly, the rigidity) of the peripheral lip or other outer member and/or the interior features or members can be determined based on one or more factors, such as, for example and without limitation, the material(s) used, the durometer, rigidity and/or flexibility of these elements, the thickness, height, length and/or other dimensions of these elements, shape of these elements and/or the like. In some embodiments, even where the internal face features 140 are flexible, they may still have the required characteristics, components, abrasive features 148 and/or other features, properties and/or characteristics to sufficiently abrade a skin surface as the tip 100 is advanced or otherwise moved along or relative to a skin surface during a treatment procedure.

[0186] In some embodiments, the durometer and/or other physical property (e.g., softness, hardness, stiffness and/or other property related to flexibility) of the interior feature(s) or element(s) 140 (e.g., spiral protruding member) may vary along one or more portions as the internal face feature 140 progresses across the base surface 131 of the tip 100. For example, the durometer or stiffness/softness/flexibility can change along the interior member 140 as the member progresses radially outwardly (e.g., towards the peripheral lip 132). In some embodiments, the interior member or feature 140 has a durometer of M2 along one portion or location and a different durometer of Ml along a different portion or location of the member or feature. The durometer (e.g., and/or another physical property or indication of softness, hardness and/or flexibility) of the interior feature 140 may vary such that the M2 is less resistive to compressive force than Ml, and Ml is less resistive to compressive force than P. As such, in such a configuration, even without modifying the height of the interior features or member 140, the seal made by the peripheral lip 132 against the subject’s skin surface may be improved or otherwise enhanced (e.g., the temporary seal can be more complete, more secure, longer lasting, etc.) during a skin treatment procedure. In some embodiments, the portions of the internal face feature 140 with a durometer of M2 can be more resistive to compressive force than portions of the internal face feature 140 with a durometer of Ml. In some embodiments, the interior feature or member can comprise a flexibility to allow at least a portion of the internal face feature to bend or otherwise deform (e.g., in a direction opposite or substantially opposite of the distal end of the tip and corresponding skin-tip interface). Accordingly, in certain arrangements, one or more portions of the interior member or feature 140 can be flexible enough to elastically deform during use (e.g., as the tip 100 is moved along

EDGE.218WO -31- Knobbe, Martens, Olson & Bear, LLP the skin surface during a treatment procedure) to help create a better temporary seal (e.g., increase the quality of a temporary seal formed) between the subject’s skin surface and the peripheral lip (and thus, the tip).

[0187] According to some embodiments, a portion of the tip 100 contacting the skin surface, such as the peripheral lip 132 and/or the interior or internal features or members 140, can assist with abrading (e.g., exfoliating, removing, agitating, etc.) skin tissue when the handpiece and tip are moved relative to the skin surface being treated. In some embodiments, the interior features 140 can be configured to be used in a microdermabrasion procedure. As depicted in FIGS. 4A and 4B, surfaces of, at, near or along of a distal portion 130 of a tip 100 which contact or may contact the subject’s skin surface can include one or more abrasive feature, member, element and/or configuration 148. Such abrasive features can assist with the exfoliation of a subject’ s skin during a procedure. In some embodiments, the abrasive elements and/or feature(s) 148 are positioned along an interior defined by a peripheral lip 132. In other embodiments, the peripheral lip 132 comprises the abrasive feature 148, at least in part, either in addition to or in lieu of any additional (e.g., interior) abrading interior features 140. In some embodiments, the abrasive elements or features 148 comprise one or more materials (e.g., one or more additives) that are incorporated within or into one or more portions of the peripheral lip or other outer member 132 and/or the interior feature or element 140 (e.g., during its manufacturing). In some embodiments, the abrasive materials or features can be impregnated or otherwise embedded or at least partially positioned or secured within at least a portion of the internal face features 140, peripheral lip 132, or other portions contacting the skin surface during a treatment procedure. Such abrasive materials and/or resulting configurations of the peripheral lip and/or the interior elements or member can help with the abrasion, removal, exfoliation and/or other manipulation of the skin surface being treated.

[0188] According to some embodiments, the peripheral lip and/or the interior elements or features can include one or more physical features (e.g., ribbing, sharper edges, pored/porous structure, openings or recesses, undulations, etc.), as desired or required. Such configuration can enhance exfoliation and/or other aspects of a skin treatment procedure, regardless of whether the lip 132, the interior elements 140 and/or other portions of the tip 100 include abrasive materials. In some embodiments, the abrasive feature(s) 148 may comprise sharp or substantially sharp features and/or configuration to assist with abrading skin tissue.

EDGE.218WO -32- Knobbe, Martens, Olson & Bear, LLP In some arrangements, such features are incorporated in the tip (e.g., as part of a unitary structure with the tip, to form a monolithic or unitary body with the internal face features 140, the peripheral lip 132, and/or any other portion of the tip 100 designed to contact the skin surface during use). In some embodiments, the abrasive feature(s) 148 may comprise one or more treatment materials (e.g., chemical compositions, serums, etc.) such as for example and without limitation, salicylic acid, glycolic acid, mandelic acid, lactic acid, other cleansing or rinsing agents, acids and/or other materials that enhance extraction of sebum, blackheads and/or other unwanted materials from a targeted skin surface, boosters, or other treatment materials beneficial to the skin surface and/or a skin treatment procedure. In some embodiment, a tip may include a combination (e.g., two or more, multiple, some, all, etc.) of any abrasive features, elements and/or configurations described herein.

[0189] Further, according to some embodiments, one or more interior members or features 140 can define desired flow patterns (e.g., flow paths, expected flow path, treatment fluid path, etc.) for any fluid entering the distal portion 130 of the tip. For example, as depicted in FIG. 5, fluid that enters the distal portion 130 of the tip (e.g., via one fluid inlet port 150) can be directed in a pattern represented by fluid flow arrow Fl. In some arrangements, such fluid can exit the distal portion of the tip through one or more vacuum or suction ports or openings 154. In some embodiments, a vacuum source can be in fluid communication with the one or more vacuum or suction ports or openings 154 included in a tip such that treatment fluid is drawn from the fluid inlet port 150, across the skin surface by the expected flow path defined by the one or more internal face features 140 to the one or more vacuum or suction port or openings 154. As shown and noted above, the depicted tip 100 comprises a total of one vacuum or suction port or opening 154. However, a tip can include additional vacuum or suction ports or openings 154 (e.g., 2, 3, 4, 5, more than 5, etc.), as desired or required.

[0190] With continued attention to FIG. 5, the tip 100 can be configured to create a tortuous or generally tortuous flow pattern from the inlet or fluid delivery port(s) 150 to one or more of the vacuum, waste or suction port(s) or opening(s) 154. This can help prevent or reduce the likelihood of short-circuiting between the inlet port(s) or opening(s) 150 and the vacuum or waste port(s) or opening(s) 154, thereby increasing the residence time of treatment materials delivered from the fluid inlet port 150 to the distal portion 130 (and thus, the skin being treated). In some embodiments, this can improve the efficacy of a procedure and provide

EDGE.218WO -33- Knobbe, Martens, Olson & Bear, LLP better or enhanced results to the subject undergoing a treatment procedure (e.g., greater penetration of fluids into skin tissue, greater velocity of fluids being delivered to the tip 100, etc.).

[0191] In embodiments where a peripheral lip 132 has a higher height or distal extent than the interior features or members (e.g., a first interior feature having a first height or distal extent 141, a second interior feature having a second height or distal extent 142, a third interior feature having a third height or distal extent 143 and a fourth interior feature having a height or distal extent 144, etc.), a temporary seal formed between the peripheral lip 132 and the subject’s skin surface can be improved (e.g., can be represented by better, more consistent contact between the lip and adjacent skin surface), thereby improving or enhancing the efficacy of a procedure. In some embodiments, a seal can also be formed between a distal- most portion of an internal face feature and the skin surface (e.g., such that treatment fluid is prevented or substantially prevented (or otherwise obstructed and/or diverted) from passing distally over the internal face feature 140 during a treatment procedure).

[0192] As depicted by the embodiment in FIG. 5, treatment fluid and/or other materials are delivered to the distal portion 130 of the tip 100 through one or more fluid inlet ports or openings 150 according to one embodiment of the present disclosure. From there, fluid and/or materials can flow and/or otherwise be directed through one or more channels or passages (e.g., in a radially outward direction, as generally represented by Fl). Therefore, in some embodiments, fluid and/or other materials can be delivered to a generally central area of the tip and radiate outwardly to encompass a larger skin surface area for treatment. From there, fluid can be split or otherwise divided and/or diverted (e.g., as denoted by diversion point DI) in two or more directions. Such directions can be non-parallel or angled relative to one another. In one embodiment, the directions of fluid flow after divergence point DI are angled and generally opposite of one another (e.g., as generally represented by F2) towards sections of the peripheral lip 132. Fluid and/or other materials can then be directed to, near and/or along the peripheral lip 132. In some embodiments, fluid and/or other materials will then be directed to one or more waste or vacuum ports 154 for removal from the distal portion 130 of the tip 100.

[0193] The distal portion 130 of the tip 100 can be angled relative to the proximal portion 110 of the tip 100. In the embodiment depicted in FIGS. 6A and 6B, the angle 0 represents the angle between the plane defined by the distal-most portion of the tip (e.g., along

EDGE.218WO -34- Knobbe, Martens, Olson & Bear, LLP the distal end of the distal portion 130) and both (i) the longitudinal axis of the tip (and the handpiece to which is secures) and (ii) an orthogonal or perpendicular axis of the longitudinal axis through the use of a curved or partially circular transition 118. Such an angled configuration can provide one or more advantages or benefits to a user who is manipulating a handpiece during the execution of a skin treatment procedure, including increasing the surface area of such a plane, providing improved ergonomics, improving functionality and comfort to the user, and/or the like. In some embodiments, 0 can be 10 to 20 degrees (e.g., 10 to 11, 11 to 12, 12 to 13, 13 to 14, 14 to 15, 15 to 16, 16 to 17, 18 to 19, 19 to 20 degrees, angles between the foregoing ranges, etc.). In other embodiments, the angle 0 is less than 10 degrees or greater than 20 degrees, as desired or required.

[0194] FIG. 7 schematically illustrates a tip 100 secured to a handpiece 10 (e.g., a distal end of a handpiece 10). During one embodiment of a skin treatment procedure, fluid and/or other treatment materials can flow or be directed from the fluid delivery port or opening 22 of the handpiece 10 through the fluid connector 120 into the one or more opening(s) 122. Such openings 122 can direct fluid and/or other materials to one or more fluid inlet ports 150 of the tip 100. After the fluid and/or other treatment material flow along the tip (e.g., through a torturous or other path of the tip 100, as guided by the at least one interior members or features 140), such fluid and/or treatment materials can enter one or more of the vacuum, suction and/or waste ports or openings 154 of the tip 100. There, such fluids or materials can be directed to a waste suction collection region 126 to be eventually removed from the tip and distal end of the assembly by the one or more vacuum or waste ports or openings 24 of the distal end 12 of the handpiece 10. The vacuum ports or openings 24 can be located at any location along or near the distal end 12 of the handpiece 10 that is adjacent or near the waste suction collection region 126. As such, in some arrangements, the vacuum ports or openings 24 are not in the position indicated by FIG. 7.

[0195] With continued reference to FIG. 7, in some embodiments, the fluid connector 120 does not bifurcate or otherwise prevent flow across the cross-sectional area of the waste suction collection region 126. Thus, in such a configuration, if the vacuum port or opening 24 was located on the left side of the distal end 12 of the handpiece 10, then any fluid or other treatment materials entering the waste suction collection region 126 from the vacuum or suction port or opening 154 on the right side of the tip 100 could be able to exit the waste

EDGE.218WO -35- Knobbe, Martens, Olson & Bear, LLP suction collection region 126 through the vacuum port or opening 24 on the left side of the distal end 12 of the handpiece 10. In some embodiments, all vacuum or suction ports or openings 154 of the tip 100 can be in fluid communication with the same waste suction collection region 126, which can have its contents drained by the handpiece 10 at the vacuum port or opening 24.

[0196] In some embodiments, the fluid connector 120 can receive a treatment fluid from the handpiece 10 by connecting at the fluid delivery port or opening 22 in the distal end 12 of the handpiece 10. The fluid connector 120 need not travel as far into the fluid delivery port or opening 22 of the distal end 12 of the handpiece 10 as depicted in FIG. 7. Instead, it can transfer proximally enough to create a temporary seal separating or substantially separating the fluid delivery port or opening 22 from the vacuum port or opening 24 (e.g., to prevent or reduce the likelihood of short-circuiting of the fluids and/or other treatment materials delivered to the tip during a procedure).

[0197] In some embodiments, as shown in FIGS. 8 A through 8E, the tip 800 can include a modular or multi-component or multi-part construction or configuration. As shown, the tip 800 can include at least some characteristics that are similar to other embodiments disclosed herein (e.g., such as a distal portion 830 with a peripheral lip 832 and internal extended features 840 configured to contact a skin surface). In some embodiments, the tip 800 comprises a first or distal portion or component 830 and a second or proximal portion or component 810. Such portions 830, 810 can be configured to connect or secure to one another (e.g., fixedly, removably, during manufacture or assembly, etc.) to form the tip 800. The tip portions can connect to one another using one or more attachment or securement technologies or methods, such as, for example and without limitation, press fit connection, friction fit connection, mechanical coupling or connection of adjacent features or portions (e.g., protrusions and corresponding openings, other engagement features, etc.), adhesives, other mechanical fasteners or connectors and/or the like.

[0198] In some embodiments, the relative flexibility or rigidity of the first or distal portion 830 can be different than that of the second or proximal portion 810, as desired or required. For example, in one arrangement, the distal portion or component 830 includes a construction or configuration that is more flexible (e.g., less rigid) than the proximal portion or component 810. In some embodiments, the distal portion or component 830 includes a

EDGE.218WO -36- Knobbe, Martens, Olson & Bear, LLP construction or configuration that is less flexible (e.g., more rigid) than the proximal portion or component 810. In yet other arrangements, the relative flexibility of the two portions or components 810, 830 can be similar or substantially similar. In some embodiments, the tip portions can be configured to deform sufficiently to interface together and form a tip suitable for use during a skin treatment procedure as described herein.

[0199] In some embodiments, the tip includes a distal portion 830 that is more flexible (e.g., less rigid) than the proximal portion 810. For instance, some, all or substantially all of the materials (e.g., the resulting material composition where two or more materials are used) in the distal portion 830 of the tip 800 can have a lower durometer than the materials (or the resulting material composition) of the proximal portion 810. In some embodiments, the distal portion 830 is at least partially supported by a more rigid (less flexible) proximal portion 810. Thus, the proximal portion can have a higher durometer or greater rigidity. This can be advantageous as the proximal portion can be configured to connect the tip 800 to the handpiece 10, and portions of the distal portion can contact the skin surface during use. As such, regions of the tip 800 that are configured to contact a subject’s skin surface during a skin treatment procedure (e.g., the peripheral lip and other portions of the distal portion 830) can be configured to more easily deform (e.g., to conform, at least partially, to the contours and/or other features of the skin surface being treated). As discussed, the distal portion 830 of the tip can be configured to create a seal (e.g., at least a partial seal, at least a temporary seal, etc.) with a portion of the targeted skin surface at or along the peripheral lip 832. In some embodiments, the configuration of the distal portion 830 of the tip can be adapted to allow the interior feature(s) and/or element(s) (e.g., spiral protruding element, protruding members, abrasive members, etc.) 840 and/or one or more other features or elements (e.g., one or more raised openings 822) to selectively abrade skin tissue as the tip is moved relative to the subject’s skin surface. In some embodiments, while the distal portion 830 may be flexible relative to the proximal portion 810, it can still have the required rigidity, characteristics, abrasive features and/or other properties or characteristics needed to abrade (e.g., to a desired or desired extent) the skin surface as the tip 800 is advanced along (e.g., translated or otherwise moved laterally relative to) the skin surface during a treatment procedure. In some embodiments, the peripheral or outer lip or member 832 can form a temporary seal with the skin surface while the internal extended features 840 contact the skin surface.

EDGE.218WO -37- Knobbe, Martens, Olson & Bear, LLP [0200] With continued reference to the cross-sectional view of FIG. 8C, in comparison to other tip arrangements disclosed herein, the tip includes openings 822 that arc raised or elevated relative to the tip base (e.g., surface 831). In other words, the openings or ports are positioned more distally relative to the base 831. Such openings 822 can be used in lieu of or in addition to any other openings or ports (e.g., openings or ports located along the base) to remove spent treatment fluids, exfoliated skin tissue and/or other waste away from the tip. In some embodiments, the tip 800 can comprise openings along the tip base surface 831 in addition to the one or more raised openings 822. In some embodiments, the use of elevated (or distally located) waste openings 822 can further enhance the exfoliating properties of the tip. For example, such waste openings 822 can be configured to contribute to the abrasive nature of the interior elements, members or features 840 of the tip 800. Further, in some embodiments, such raised openings 822 can increase the overall and/or localized rigidity to the tip 800. Raised openings 822 can protrude from the tip base surface 831 less distally than certain other interior portions or features of the distal portion 830 and/or the overall tip 800 (e.g., less distally relative to the interior members or features 840). In some embodiments the one or more raised openings 822 can be configured to have abrasive features along their distal most surface and/or can be configured to abrade the skin similar’ to internal extended features 840. In some embodiments, the internal extended features 840 can include abrasive features along their distal ends substantially similar' to other abrasive features described herein.

[0201] In some embodiments, the one or more openings or ports allowing waste to drain or otherwise be removed from the distal portion 830 can be located elsewhere on the raised portions (e.g., such that the distal-most surface of the raised surface does not have the opening(s)). In some embodiments, the openings or ports 822 can be located along the sides of the raised surfaces, as desired or required.

[0202] According to some embodiments, due to the flexible nature of the distal portion 830 (e.g., flexible distal portion relative to the flexibility of the proximal portion 810 of the tip 800), even if one or more of the raised openings 822 are flush or generally fluid with the skin surface with the skin, the vacuum provided by the handpiece 10 can at least partially deform either the raised openings 822 or the skin to allow for treatment fluid to flow through the raised opening 822 to the handpiece 10. The distal surfaces of the internal extended features 840, as well as the one or more raised openings 822, can make contact with the targeted

EDGE.218WO -38- Knobbe, Martens, Olson & Bear, LLP skin surface, even though the distal end of the peripheral lip 832 may not be as distal as the distal portion of the peripheral lip 832. Portions where the interior features 840 contact skin tissue, combined with the vacuum force exerted through the one or more openings 822 to the handpiece 10, can facilitate cleansing and/or other treatment steps or processes related to the skin (e.g., via, at least in part, deformation and application of treatment fluid to the skin cells). In embodiments that have the openings located not on the distal-most surface of the raised surfaces, fluid can drain from the tip 800 by the openings along the sides of the raised surfaces.

[0203] Furthermore, the one or more raised openings 822 need not protrude by the same height or distal extent as each other. For example, three of the raised openings 822 depicted in FIGS. 8 A through 8D have a different height or distal extent than other raised openings 822. Other configurations of raised openings 822 can also be used, as desired or required. The tip 800 depicted in FIGS. 8 A to 8D includes a total of six openings, but more or less raised openings 822 can be included, as desired or required.

[0204] FIG. 8B depicts the proximal portion 810 and distal portion 830 of the multi-component or multi-part or portion tip 800 (e.g., modular tip) as separate components, portions or pieces. As shown in FIG. 8C, the proximal portion 810 can include one or more geometric features that can help interact and engage portion of the distal portion 830 of the tip. For example, the proximal portion 810 can include one or more interface points 836 that are shaped, sized, located and otherwise configured to engage and interface with corresponding features (e.g., recesses, detents, negative spaces, etc.) of the distal portion 830, as shown in FIG. 8C. The specific type of engagement features can be reversed and/or completely different in other embodiments, as desired or required.

[0205] In some embodiments, the distal portion 830 of the tip 800 has a sufficient flexibility (e.g., a sufficiently low durometer) so that at least some regions or areas of the distal portion 830 can at least partially deform when the tip 800 is positioned along a skin surface of a subject. For example, the peripheral lip and/or other portions of the distal portion 830 can deform and/or otherwise change shape so as to at least partially conform to the contours and/or other geometrical shapes the distal end of the tip will encounter during use. For example, portions of the distal portion 830 of the tip 800 can be configured to generally conform to the subject’s face, scalp and other skin or body portions being targeted by a particular treatment procedure. In some embodiments, different portions of the distal portion 830 can have

EDGE.218WO -39- Knobbe, Martens, Olson & Bear, LLP different durometers, such that some portions deform more than others (e.g., based on the varying degree of force applied to the skin using the system by the user). For instance, in some embodiments, the internal extended features 840 can deform less than the one or more raised openings 822 or the peripheral lip 832. In some embodiments, the peripheral lip 832 can deform sufficiently to have the internal extended features 840 contact the skin surface during expected instances of a skin treatment procedure.

[0206] In some embodiments, one or more tip interface points or features 836 can be used to couple (e.g., fixedly, releasably, etc.) the distal portion 830 and the proximal portion 810 of the tip 800. FIG. 8C shows a cross-section of the tip 800 after the proximal portion 810 and distal portion 830 have been secured to each other (e.g., interacted at or along inter-tip interface point(s) 836). FIG. 8D shows the tip 800 of FIG. 8A from the perspective of the proximal end of the tip 800 to further show the inter-tip interface points 836 where the distal portion 830 connects to the proximal portion 810. The proximal ends of the one or more raised openings 822 and the internal extended features 840 that extend proximally beyond the tip base surface 831 can be wider than the inter-tip interface point 836 holes or openings. This can provide additional strength and security to the connection between the proximal portion 810 and distal portion 830, additional resistance to rotation for the proximal portion 810 relative to the distal portion 830 and/or one or more other benefits or advantages. In some embodiments, portions of the internal extended features 840 or one or more raised openings 822 on their proximal end can include lateral protrusions that at least partially deform during connection of the proximal portion 810 and the distal portion 830 (e.g., to pass through corresponding openings in the proximal portion 810). In some embodiments, once the proximal portion 810 and distal portion 830 are sufficiently connected, the inter-tip interface points 836 or protrusions can revert to their non-compressed state, being partially located proximal the proximal-side opening of the proximal portion 810 to receive the distal portion 830.

[0207] FIG. 8E shows one embodiment of an expected fluid flow pattern (e.g., fluid flow pathway, fluid flow path, expected flow path, expected flow pathway, expected fluid flow pathway, defined pathway, defined path) from the fluid inlet port 850 to the one or more raised openings 822. As fluid enters the volume prescribed by the peripheral lip 832, it can at least partially split or otherwise divided and/or diverted (e.g., as denoted by diversion point DI) in two or more directions, and/or travel generally distally towards the treatment area of the skin.

EDGE.218WO -40- Knobbe, Martens, Olson & Bear, LLP As such, in some embodiments, fluid does not necessarily travel or need to travel adjacent or close to the tip base surface 831 (e.g., as it can with certain other tip embodiments). Treatment fluid can pass through the volume, space, area or region prescribed by the peripheral lip 832, the tip base surface 831 and the contacted skin surface. Treatment fluid can diverge and/or converge after passing along, around, or near tip features (e.g., at least partially around the interior protruding features or members 840, as denoted by example flow pattern depicted in FIG. 8E with convergence points Cl and divergence points D2). In some embodiments, one or more portions (e.g., distal surfaces) of the interior protruding features or members 840 can help massage, agitate, abrade and/or otherwise manipulate the skin as the internal extended features 840 passes over the skin surface, providing one or more benefits or advantages (e.g., partially opening pores for the treatment fluid to enter into or onto the dermis, removing at least a portion of the stratum comeum, otherwise loosening sebum, blackheads and/or other unwanted materials contained within the skin surface being treated and/or the like). In some embodiments, treatment fluid and/or other material can pass along portions of the internal extended feature 840 and ultimately exit the distal portion 830 by the one or more raised openings 822 in fluid communication with the vacuum port or opening 24 of the handpiece 10.

[0208] In some embodiments, the height (or distal extent) of the one or more internal members or features 840 is different than the height (or distal extent) of the one or more one or more raised openings 822. In some embodiments, the height or distal extent of the one or more internal members or features 840 is different than the height or distal extent of the peripheral lip 832 relative to the tip base surface 831 of the tip 800. In some embodiments, the height or distal extent of the peripheral lip 832 is greater than the height or distal extent of the one or more internal extended features 840. In some embodiments, the height or distal extent of the one or more internal extended features 840 is greater than the height or distal extent of the one or more raised openings 822. In some embodiments, the heights or distal extents of some of the one or more raised openings 822 are greater than the height or distal extent of some of the other one or more one or more raised openings 822. In some embodiments, the height or distal extent of the one or more raised openings 822 is greater than the height or distal extent of the fluid inlet port 850. In some embodiments, the height or distal extent of the fluid inlet port 850 is greater than the height or distal extent of the tip base surface 831.

EDGE.218WO -41- Knobbe, Martens, Olson & Bear, LLP [0209] In some embodiments, the tip 800 can have a unitary or monolithic construction, where the proximal portion 810 and distal portion 830 arc fixedly attached. In such embodiments, the tip 800 can still comprise more than one material, and can have various features which vary in durometer, surface quality and/or other defining characteristics, including features of other tips as disclosed herein, as desired or required.

[0210] In an alternative embodiment, as illustrated in FIGS. 9 A to 9E, an adaptor interface or other proximal portion 910 can be used to couple a distal portion 930 of a tip 900 to the distal end 12 of the handpiece (see, e.g., FIG. 9C). The distal portion 930 depicted in FIG. 9A is partially hidden to show the interface between the distal portion 930 and the proximal portion 910. In some embodiments, the distal portion 930 completely circumscribes the proximal portion 910 such that fluid can flow through the tip according to flow rates described otherwise herein. The adaptor interface or other proximal portion 910 can be incorporated into any tip design, including any other tips illustrated and/or discussed herein, or equivalents or related versions thereof. Therefore, in some arrangements, an adapter or a proximal portion 910 of a tip 900 can be used to secure the tip to the handpiece. The adapter or other proximal portion 910 can be fixedly or releasably (or separably) coupled or otherwise secured to one or more other portions of the tip (e.g., the distal portion 930 of the tip 900), as desired or required. In some embodiments, the proximal portion 910 is secured to the distal portion 930 of the tip 900 by a mechanical connection, a threaded connection, a friction fit, a press fit, and/or any other connection or coupling method or technology as described herein.

[0211] According to some arrangements, the distal portion 930 of the tip 900 has the same, similar or substantially the same or similar features as the distal portion 130 of the tip 100. FIG. 9A illustrates a cross-sectional view of one embodiment of the interaction between the distal portion 930 and the adapter or proximal portion 910 of the tip 900. The two portions or components can be configured to couple (e.g., fixedly, removably, separably, etc.) using one or more connection or securement technologies or methods, such as, for example and without limitation, friction fit or pressure fit connection, press fit, adhesives, mechanical engagement features and/or the like. See, for example, FIGS. 9B and 9C, depicting example embodiments of how the proximal portion 910, distal portion 930, and handpiece 10 can connect to form a body suitable for a skin treatment procedure. In some embodiments, the tip 900 can include features such as a proximal cylindrical portion 914, fluid connector 920, one

EDGE.218WO -42- Knobbe, Martens, Olson & Bear, LLP or more openings 922, waste suction collection region 926, internal face feature 940, and vacuum or suction port or opening 954, which, in some arrangements, can act in a substantially similar fashion to correlating features of a tip 100 as described herein, as desired or required.

[0212] With continued reference to the tip embodiment of FIGS. 9 A to 9E, the adaptor interface or proximal portion 910 of the tip 900 is used to connect the distal portion 930 of the tip to the distal end 12 of the handpiece 10. Utilization of an adaptor interface or other proximal portion 910 may be beneficial where the most or all of the distal portion 930 of the tip 900 comprises a highly elastic material, such that the adaptor interface or proximal portion 910 could provide sufficient rigidity to the tip. This can improve the ability of the tip 900 to be securely positioned along a distal end of a handpiece and/or otherwise improve the functionality of the tip during use and/or provide one or more other benefit or advantages (e.g., increase the tip’ s abrasion capability, function and/or effectiveness, increase the tip’ s resistance to collapsing under vacuum pressure and/or other forces or moments to which the tip may be subjected during use and/or the like). Advantageously, in some embodiments, this can also decrease complexity during manufacturing of a tip, eliminating the requirement of manufacturing a single unitary body with made of multiple different durometer materials or characteristics as one piece. Rather, in such configurations, two or more pieces or portions, such as a proximal portion 910 and a distal portion 930, can be designed to work in tandem and form a tip 900. In some embodiments, three or more portions of a tip can be made of separate parts to form a singular body suitable for use during a skin treatment procedure.

[0213] With respect to the embodiment illustrated in FIGS . 9A to 9E, fluid and/or other treatment materials delivered to the tip (e.g., through one or more passages or openings of the handpiece, tip, etc.) would still be able to flow from the one or more openings 122 to the fluid delivery port or opening 22 of the handpiece 10 to the distal portion 930 of the tip 900. However, in some embodiments of such a configuration, fluids and/or other treatment materials can travel along at least a partially tortuous treatment fluid flow path through an interior surface or portion of the adaptor interface or proximal portion 910, defined by internal face features 940 in a way substantially similar to other fluid flow paths defined by internal face features disclosed herein. In some arrangements, after the fluid is delivered and/or dispersed within the interior region or area circumscribed or otherwise surrounded by the peripheral lip 932, fluid can exit the distal portion 930 (e.g., with the assistance of vacuum or

EDGE.218WO -43- Knobbe, Martens, Olson & Bear, LLP suction, via one or more vacuum or waste ports or openings 954). In some embodiments, waste is directed from the distal end or portion of the tip to a waste suction collection region 926, which can be formed as an area between the proximal portion 910, distal portion 930, and the distal end 12 of the handpiece 10. Waste can be removed via vacuum or suction forces applied through the vacuum port or opening 24 at, near or along the distal end 12 of the handpiece 10. FIGS. 9D and 9E show views of the tip 900 and adaptor interface or proximal portion 910, respectively. In some embodiments, portions of the proximal portion 910 and distal portion 930 can be configured to at least partially interconnect to assist in forming a seal between the two parts, in a method substantially similar to other two-part tips, such as tip 800, as described herein.

[0214] In alternative embodiments, as illustrated in FIG. 10A and 10B, the peripheral lip 132 can include two or more different portions or sections 1034, 1036. These different portions or sections can be based on the use of differing materials or groups of materials, different shapes, different sizes, different (e.g., separate) components or sections and/or different dimensions (e.g., thickness of width of a particular component or portion) and/or the like to result in at least one physical distinctions between the two portions 1034, 1036. In the depicted arrangement, the portions or sections 1034, 1036 are generally separated in the proximal-distal direction (e.g., in a direction along a longitudinal axis of the tip). However, distinctions between varying (e.g., adjacent) portions or regions of the peripheral lip and/or other regions of a distal portion of a tip can be related to variations in other directions (e.g., horizontal or radial) either in addition to or in lieu of vertically oriented distinctions. In some embodiments, the first portion 1034 can be more radially inward than the second portion 1036, such that the area defined by peripheral lip is contacting only the first portion 1034 and not the second portion 1036.

[0215] With continued reference to FIGS. 10A and 10B, the peripheral lip 132 or other distal portion of the tip can comprise a peripheral lip proximal (or first) section 1034 and a peripheral lip distal (or second) section 1036. The flexibility or rigidity of one section 1034, 1036 can be different that the flexibility or rigidity of another section or portion, as desired or required. For instance, in embodiments where the peripheral lip comprises one or more elastic (e.g., elastomeric, other polymeric, etc.) materials and/or construction, the durometer of the peripheral lip proximal or first section 1034 may be different than the durometer of the

EDGE.218WO -44- Knobbe, Martens, Olson & Bear, LLP peripheral lip distal or second section 1036. In some embodiments, the peripheral lip distal section 1036 has the same elasticity or substantially the same elasticity as the internal face features. In some embodiments, the peripheral lip proximal section 1034 and the peripheral lip distal section 1036 (and/or other any additional and/or different portions or regions of a peripheral lip) may be permanently or separably connected to one another.

[0216] In some embodiments, the peripheral lip distal section 1036 can be less flexible (e.g., have a higher durometer) than the peripheral lip proximal section 1034 such that the peripheral lip distal section 1036 at least partially abrades skin tissue during a skin treatment procedure, and the peripheral lip proximal section 1034 assists in forming a temporary seal while the tip is pressed against the skin surface. In some embodiments, the peripheral lip distal section 1036 can be more flexible (e.g., have a lower durometer) than the peripheral lip proximal section 1034 such that the peripheral lip proximal section 1034 can deform as the tip is pressed against the skin surface and the peripheral lip distal section 1036 assists in constant contact between the peripheral lip proximal section 1034 and the skin surface.

[0217] In some embodiments, the peripheral lip can comprise three or more materials, as desired or required. Having the peripheral lip be formed of or comprising multiple materials can assist in providing desirable surface treatment effects during a skin treatment, such as for example by balancing the abrasive nature of a tip with its ability to form a seal against the skin surface during a skin treatment procedure.

[0218] FIG. 10B depicts a cross-sectional side view of the distal portion 130 of the tip with the peripheral lip 132 comprising a peripheral lip proximal section 1034 and a peripheral lip distal section 1036. A tip having a peripheral lip 132 with two or more sections, regions and/or portions (e.g., a peripheral lip proximal section 1034 and a peripheral lip distal section 1036) can provide several benefits and advantages, such as, for example, providing a desired amount or level of rigidity to the tip, providing a desired level of flexibility along the distal end of the tip (e.g., to adjust to contours of a scape, a face or other skin surface being treated, etc.), selectively abrading the skin surface with the distal-most portion of the peripheral lip as the tip is advanced along the skin surface, increasingly the likelihood of a temporary seal being formed along the skin surface, and/or the like.

EDGE.218WO -45- Knobbe, Martens, Olson & Bear, LLP [0219] FIGS. 11 A to 1 ID illustrate another embodiment of a tip 1 100 configured to be used with the handpiece 10 for skin treatment purposes (e.g., microdermabrasion, other skin treatment procedures, etc.). As shown, the distal end of the tip can include a plurality of cells or zones, some or all of which are fluidly interconnected (e.g., via one or more channels and/or other passages). In the depicted arrangement, the tip 1100 includes internal face features 1140 that subdivide the area prescribed, defined or otherwise surrounded by the peripheral lip 1130 into a series of partitioned cells 1141. As noted, such cells or zones can be joined or interconnected by one or more inter-cell or inter-zone passages, channels or other connections 1142. In some embodiments, the internal face features or members 1140 that define or are otherwise included in the partitioned cells 1141 can contact the skin surface during a skin treatment procedure such that treatment fluid is prevented or substantially prevented from passing over the internal face features 1140. In some embodiments, the portions of the internal face features 1140 and peripheral lip 1130 that contact the skin surface can be configured to at least partially abrade skin tissue. This can be accomplished, for example and without limitation, by having a sufficiently sharp edge or other features, the inclusion of abrasive features or materials and/or the like, such that when the tip 1100 is advanced along the skin surface, at least a portion of the stratum corneum is removed from the skin during a skin treatment procedure.

[0220] In some embodiments, when fluid enters the interior area defined or prescribed by the peripheral lip 1130 (e.g., via one or more fluid inlet ports 1150), it can fill or at least partially fill or occupy the partitioned cell(s) 1141 that is/are directly connected to the fluid inlet port 1150 by cell connections (e.g., fluid connections) 1142 between the partitioned cell 1141 with the fluid inlet port 1150 and neighboring partitioned cells 1141. From any such direct fluidly connected cells, regions or zones, fluid can be transferred to adjacent partitioned cells or zones 1141 via one or more cell connections (e.g., passages, channels, openings, etc.) 1142. In some embodiments, the partitioned cells or zones 1141 are connected by cell connections 1142 in such a way that treatment fluid transferred to the tip can be dispersed (e.g., uniformly, non-uniformly, etc.) through various portions or regions of the entire prescribed by the peripheral lip 1130. The cell connections 1142 can require the treatment fluid entering the area defined by the peripheral lip 1130 and the internal face features 1140 of the partitioned cells 1141 to contact the skin surface adjacent the tip 1100 during a skin treatment procedure.

EDGE.218WO -46- Knobbe, Martens, Olson & Bear, LLP In some arrangements, connections (e.g., passages, channels, openings, etc.) can also be included to allow the fluid entering the distal portion of the tip (e.g., via one or more inlet ports 1150) to pass to or near the peripheral lip 1130.

[0221] In some embodiments, fluids and/or other treatment materials delivered to the tip can be further diverted or directed through the use of one or more flow directors or diverters 1143 placed within partitioned cells 1141. In some embodiments, the flow directors 1143 can define the treatment material flow path to be more tortuous (e.g., extend the length of the treatment flow path along the skin surface). Such flow director or diverter members 1143 can be located at or near the cell connections 1142 joining two or more cells, and/or proximal an opening 1122 that allows treatment fluid to drain from the tip 1100. The flow directors or diverters 1143 can have the same height or substantially the same height (e.g., relative to the tip base surface 1131, based on the distal extent, etc.) as the interior features or members 1140 (e.g., spiral member, other protruding member(s) or feature(s), etc.) of the tip. In other arrangements, the height and/or the distal extent of the flow diverter or directing members or features 1143 can be different (e.g., greater or less than) a corresponding height and/or distal extent of any interior members, as desired or required.

[0222] According to some embodiments, inter-cell or inter-zone connections (e.g., passages, channels, openings, etc.) 1142 can be flush or substantially flush with the tip base surface 1131 (e.g., such that the fluid does not need to change distal elevation) to pass from one partitioned cell 1141 to another. In some embodiments, one or more inter-cell or interzone connections 1142 can have some height relative to the tip base surface 1131. By having a configuration where a cell connection 1142 necessitates an elevation change between cell connections 1142 (e.g., the heights of neighboring partitioned cells 1141 are different or substantially different), the velocity of a fluid entering from one cell or an adjacent cell 1141 can be increased.

[0223] A partitioned cell 1141 can have multiple cell connections 1142, which can provide the partitioned cell 1141 with more fluid as well as multiple cell connections 1142 which may improve fluid distribution along the different zones or cells 1141. Fluids and/or other treatment materials can exit the distal end of the tip (e.g., the area prescribed by the peripheral lip 1130) via one or more one or more waste openings or ports 1122. In some embodiments, such waste openings or ports 1122 can be included within a partitioned cell or

EDGE.218WO -47- Knobbe, Martens, Olson & Bear, LLP zone 1141 , can be included outside of any cells or zones and/or a combination thereof. The embodiment of the tip 1100 depicted in FIG. 11A includes six waste openings 1122 radially distributed around the tip 1100. However, in other embodiments, the quantity, size, shape, location, distribution and/or other details of the waste ports or openings (and/or any inlet ports or openings) can vary, as desired or required.

[0224] According to some embodiments, as illustrated in FIGS. 11A to 11D, the distance between the tip base surface 1131 and the peripheral lip 1130 may vary for a particular tip. The height of the lip and/or interior features may vary to, for example, vary the height or distal extent of such members or features from one cell or zone to the next, as desired or required. In other embodiments, such a distance is constant.

[0225] As shown in FIG. 11C, the distance measured from a portion of the tip base surface 1131 and the peripheral lip 1130 is measured as 1 Ihl, and another distance measured from a portion of the tip base surface 1131 and the peripheral lip 1130 is measured as l lh2. The difference in height between cells can assist in enhancing the flow of fluids and/or other treatment materials between one cell or zone and the next, either in addition to or in lieu of varying the height of the cell connections 1142 between adjacent partitioned cells 1141. In some embodiments, the distance between the tip base surface 1131 and the peripheral lip 1130 can vary along the tip 1100.

[0226] For any of the embodiments disclosed herein or equivalents or related configurations thereof, a tip can include one or more features (e.g., lips, interior features, other edges or surfaces, etc.) that can help accomplish one or more goals or tasks with respect to the targeted skin surface being treated. For example, the use of such features, members and/or other details can help with exfoliation or abrasion of targeted skin, the cleaning or cleansing of such skin, the removal of sebum, blackheads and/or other unwanted materials from the skin and/or the like. For instance, in some arrangements, the skin surface areas where the interior members and/or features 1140 (e.g., protruding members) contact the skin can facilitate the cleansing of the skin (e.g., in part, due to deformation and application of treatment fluid to the skin cells). Such results can be accomplished and/or facilitated by the application of vacuum or suction along the tip, by the transfer of fluids and/or other treatment materials to the tip, by incorporation of abrasive materials to one or more portions of the tip 1100, by the manner the

EDGE.218WO -48- Knobbe, Martens, Olson & Bear, LLP aesthetician or other user manipulates the handpiece and the tip secured thereto and/or due to one or more other factors or considerations.

[0227] The materials, sections, regions, portions, components and/or the like of the tip can include a uniform durometer or other measure of flexibility. For example, the various portions and components used for the tip can have a durometer that is equal or substantially equal. In other embodiments, one or more portions or sections can have a different durometer (or other measure of flexibility or rigidity), as desired or required. In some arrangements, by way of example, the peripheral lip is softer (e.g., has a lower durometer) and is more flexible than one or more other portions, components, members and/or regions of the tip (e.g., the interior protruding member(s), other abrasive features or members, the base, the proximal end that is configured to couple the handpiece to the tip, other portions of the tip’s main body portion, etc.), as desired or required. The tip 1100 can have several of, all of, or parts of its features made of a material with a higher or lower durometer than the durometer of surrounding features. In some embodiments, the tip 1100 comprises a singular material that has a consistent durometer.

[0228] FIG. 1 ID shows one embodiment of a predicted or expected flow pattern of fluids and/or other treatment materials directed to the tip (e.g., from one or more fluid inlet ports or openings 1150 to the one or more waste or suction ports or openings 1122 present within the area prescribed by the peripheral lip 1130). In some arrangements, fluids and/or other materials initially flow or are otherwise directed radially outwardly (e.g., to or near a first partitioned cell or zone 1141). From such a location, fluids and/or other materials can be split or otherwise divided and/or diverted (e.g., as denoted by diversion point 11D1) before moving radially inwardly (e.g., a portion of which can be joined or combined with one or more other branches of fluid flow, as denoted by, for instance and just as one example, by conversion point 11CI) to, toward, near and/or in the direction of a second partitioned cell 1141.

[0229] With continued reference to FIG. 11D, regardless of whether or not fluids join or other otherwise combine with one or more other branches of treatment fluid, the fluid travels can then be directed radially outwardly (e.g., to, toward, near and/or in the direction of a third partitioned cell 1141). Once within this third cell, treatment fluid can again split to travel into a fourth partitioned cell 1141 (as denoted by diversion point 11D2). Likewise, in some arrangements, once within the fourth cell, treatment fluid can be directed toward

EDGE.218WO -49- Knobbe, Martens, Olson & Bear, LLP peripheral lip 1130 of the tip 1100, until at least partially enters a fifth cell (e.g., where at least some fluid can join or be partially combined with another branch of treatment fluid, as denoted by, for example and without limitation, conversion point 11C2). If the treatment fluid joins or is otherwise combined with another branch of treatment fluid, at least a portion of such fluid can be divided or diverted (e.g., as denoted by diversion point 11D3) to flow in a radially inward direction (e.g., to or near another (e.g., a sixth) partitioned cell 1141. In some embodiments, from there, at least some fluid can exit the area prescribed by the peripheral lip 1130 of the tip 1100 and be removed through one or more openings (e.g., passages, conduits, openings, ports, etc.) of the handpiece 10. During the path around the area defined by the peripheral lip 1130, the treatment fluid can be directed within the partitioned cells 1141 by flow directors 1143, as desired or required. In some embodiments, the flow directors 1143 can increase the distance travelled by the treatment fluid, to increase the residence time of the treatment fluid on the skin surface and/or to make the expected flow path to be more tortuous/saturate more of the skin surface. Other flow path configurations can apply, as desired or required for a particular skin treatment procedure, based on the configuration and number of partitioned cells 1141, cell connections 1142, and flow directors 1143 within a tip 1100.

[0230] In some embodiments, the distal portion of the tip 1100 and the proximal portion of the tip 1100 can be formed of multiple parts, and can interface and/or interact to form a unitary part, like other tips disclosed herein. The two portions that form the tip 1100 can have different durometers, as described with other tips herein, to provide the tip 1100 with the benefits associated with having this multi-part configuration as described herein.

[0231] In an alternative embodiment, as illustrated in FIGS. 12A through 12D, the tip 1200 can include protruding members or features 1240 that include inlet funnels 1235, internal face features 1240 such as internal walls 1242, internal bowls 1243 and/or one or more other features or members to help direct the treatment fluid in a desired pattern or manner along the distal end or portion of the tip (e.g., from one or more fluid inlet ports 1250 to the one or more waste ports or openings 1222). Similar to the tip 1100 illustrated FIGS. 11 A to 1 ID, one or more interior protruding members or features 1240 can divide the area prescribed by the peripheral lip 1230 into a series of partitioned cells or zones (e.g., cells or zones that can be joined or interconnected, at least partially, by cell connections). In the embodiment depicted in FIGS. 12A to 12D, several internal bowls 1243 defined by flow connections 1244 and

EDGE.218WO -50- Knobbe, Martens, Olson & Bear, LLP internal face features 1240 divide the are defined by the peripheral lip 1430 into several distinct areas. One or more of the protruding interior features or members 1240 can be connected by flow connections or similar features 1244 to facilitate the transmission and division of treatment fluid along the distal portion of the tip 1200. The internal face features 1240 that define the internal bowls 1243 can be configured to contact the skin surface during a skin treatment procedure such that treatment fluid is at least partially (e.g., partially, fully) prevented or obstructed (e.g., substantially prevented or obstructed) from passing over the internal face features 1240 or internal bowls 1243 during a skin treatment procedure. In some embodiments, the portions of the internal face features 1240 and peripheral lip 1230 that contact the skin surface can be configured to at least partially abrade the skin. This can be accomplished by, for example and without limitation, having a sufficiently sharp edge or other feature, the inclusion of abrasive features or materials, or otherwise as described herein, such that when the tip 1200 is advanced along the skin surface, at least a portion of the stratum comeum is removed from the skin during a skin treatment procedure.

[0232] In some embodiments, when fluid enters the area prescribed by the peripheral lip 1230 (e.g., via one or more fluid inlet ports or openings 1250), it can enter, at least partially, an inlet funnel 1235. This treatment fluid can be divided to move to one of several (e.g., three) areas bounded, at least in part, by internal walls 1242. From there, fluid can be directed, at least in part, to an internal bowl or similar feature 1243 (e.g., via one or more flow connections 1244). From there, at least a portion of the fluid can exit the internal bowl or similar feature or member 1243 (e.g., via one or more flow connections 1244) to another area surrounded by the peripheral lip 1230 and eventually exit the tip via one or more waste ports or openings 1222 (e.g., for discarding).

[0233] In some embodiments, the flow connections and/or related features 1244 of the tip 1200 are configured in such a way that the treatment fluid is dispersed (e.g., divided, diverted, etc.), at least partially, along an area prescribed by the peripheral lip 1230. In some embodiments, one or more of the interior protruding members or features 1240 are connected to (e.g., joined, formed as a single or unitary member, component or feature, etc.) the peripheral lip 1230 and the walls of the internal bowls or other recesses or features 1243. In other embodiments, the lip and interior protruding members or features arc not connected or do not otherwise form a single or continuous member or feature, as desired or required.

EDGE.218WO -51- Knobbe, Martens, Olson & Bear, LLP [0234] According to some embodiments, one or more flow connectors, flow connections and/or other fluid diversion members or features 1244 arc flush or substantially finish with the tip base surface 1231. Thus, fluid passing through such members or features 1244 may not need to change distal elevation (e.g., to pass between one or more interior protruding members or features 1240). In other embodiments, the flow connections 1244 have a different height or elevation (e.g., they form a non-planar transition relative to the tip base surface 1231). Such elevation changes between interior protruding members or features 1240 can increase the velocity of fluid directed between and/or near interior protruding members or features 1240 (e.g., since the cross-sectional area through which the fluid can pass is effectively decreased). An internal bowl or recess 1243 can have multiple (e.g., more than 2) flow connections 1244. The flow connections 1244 can be between two internal bowls or recesses 1243, between an internal bowl or recess 1243 and an area defined by an internal face feature 1240, between two areas defined by internal face features 1240 and/or the like. In some embodiments, varying the height of a flow connection 1244 relative to the tip base surface 1231 can enhance the distribution and other aspects of fluid flow along the distal end or portion of the tip (e.g., along the interior region surrounded by a peripheral lip 1230).

[0235] In some embodiments, the flow connections 1244 can, at least in part, bias or otherwise direct treatment fluid passing through the flow connection 1244 to contact the skin surface adjacent the tip 1200 during a skin treatment procedure.

[0236] During a skin treatment procedure, after the treatment fluid passes through all or substantially all of the area defined by the peripheral lip 1230, fluid exits the tip 1200 using one or more waste ports or openings 1222 arranged within the area defined by the peripheral lip 1230. The embodiment of the tip 1200 depicted in FIGS. 12A to 12D includes four openings 1222, located in cardinal directions of the area prescribed by the peripheral lip 1230. However, in other embodiments, one or more characteristics or properties of the openings and/or other aspects of the tip (e.g., quantity of openings, size, shape, dimensions, orientation or distribution of features, materials, etc.) can be varied, as desired or required.

[0237] As noted above with reference to FIGS. 11A to 11D, according to some embodiments, the distance between the tip base surface 1231 and the peripheral lip 1230 may vary for a particular tip. The height of the lip and/or interior features may vary, for example,

EDGE.218WO -52- Knobbe, Martens, Olson & Bear, LLP from one cell or zone to the next, as desired or required. In other embodiments, such a distance is constant.

[0238] As shown in FIG. 12C, the distance from the fluid inlet port 1250 and the peripheral lip 1230 is measured as 12hl at the apex of the inlet funnel 1235, as 12h2 at the base of the internal bowl 1243, as 12h3 at the base of an area prescribed by an internal wall

1242, as 12h4 at a flow connection 1244 connecting an area prescribed by an internal wall 1242 and an internal bowl 1243, and as 12h5 at a flow connection 1244 connecting an internal bowl 1243 and an area prescribed by an internal wall 1242 and the peripheral lip 1230. In some arrangements, for any of the embodiments disclosed herein, the difference in height across the area prescribed by the peripheral lip 1230 can assist in propelling, channeling or otherwise moving a fluid flow along a desired area (e.g., across the face of the tip 1200). In some embodiments, the distance between the tip base surface 1231 and the peripheral lip 1230 can vary along the tip 1200 as the treatment fluid passes through the internal bowls or features

1243, flow connections 1244 and/or other features or portions.

[0239] For any of the tip embodiments disclosed herein, including the tip 1200 illustrated in FIGS. 12A to 12D, the peripheral lip, interior protruding features or members and/or other members or features along the distal portion of the tip facilitate with the tip’s exfoliating and cleansing properties, aid in removing sebum, blackheads and/or other undesired materials from the skin and provide one or more other benefits and advantages. As discussed in greater detail herein, the removal of waste materials, the delivery of fluids and/or other treatment materials, the penetration depth of any fluids and/or treatment materials that are delivered to the tip and/or one or more other aspects of a skin treatment procedure can be improved or enhanced by the application of suction or vacuum along the tip (e.g., continuous or intermittent application of suction or vacuum through one or more openings, ports, passages, etc. of the handpiece, tip and/or other portions or components of a skin treatment system).

[0240] As noted above, the materials, sections, regions, portions, components and/or the like of the tip can include a uniform durometer or other measure of flexibility. For example, the various portions and components used for the tip can have a durometer that is equal or substantially equal. In other embodiments, one or more portions or sections can have a different durometer (or other measure of flexibility or rigidity), as desired or required. In some arrangements, by way of example, the peripheral lip is softer and more flexible than one

EDGE.218WO -53- Knobbe, Martens, Olson & Bear, LLP or more other portions, components, members and/or regions of the tip (e.g., the interior protruding mcmbcr(s), other abrasive features or members, the base, the proximal end that is configured to couple the handpiece to the tip, other portions of the tip’s main body portion, etc.), as desired or required. The tip 1200 can have several of, all of, or parts of its features made of a material with a higher or lower durometer than the durometer of surrounding features. In some embodiments, the tip 1200 comprises a singular material that has a consistent or uniform (or substantially consistent or uniform) durometer.

[0241] FIG. 12D schematically illustrates one embodiment of an expected or possible flow path for a treatment fluid directed to the distal portion of the tip (e.g., fluid entering through one or more fluid inlet ports or openings 1250 and existing through one or more waste or exit ports or openings 1222). After entering from a fluid inlet port 1250 and across the one or more inlet funnels 1235, at least a portion of fluid can be directed radially outwardly into one of three areas prescribed by an internal wall 1242. In this first area, at least some of the fluid can be divided or diverted (e.g., as denoted by diversion point 12D1) and move radially inwardly (e.g., toward an internal bowl or similar feature 1243). From there, at least a portion of the fluid can be combined with one or more other branches or fluid volumes (e.g., as denoted by conversion point 12C1). In some embodiments, a least a portion of fluid can be divided or diverted (e.g., as denoted by diversion point 12D2) to flow to one of two or more flow connections 1244 (e.g., leading to an area prescribed by the peripheral lip 1230 and/or internal walls 1242, where the fluid can exit and be removed by the handpiece 10 in a similar fashion to the treatment fluid of tip 100). Other flow path configurations can apply, as desired or required for a particular skin treatment procedure, based on, for example and without limitation, the configuration and number of areas defined by the internal walls 1242, the internal bowls, recessed or other features 1243, the flow connections 1244 and/or the like within, along or near a tip 1200.

[0242] In some embodiments, the distal portion of the tip 1200 and the proximal portion of the tip 1200 can be formed of and/or can comprises a plurality (e.g., 2, 3, more than 3) parts or portions, and can interface and/or interact to form a unitary part (e.g., like other tips disclosed herein). In some embodiments, the two or more portions that form the tip 1200 can have different durometers, as described with other tips herein (e.g., to provide the tip 1200 with the benefits associated with having this multi-part configuration as described herein).

EDGE.218WO -54- Knobbe, Martens, Olson & Bear, LLP [0243] FIGS. 13A to 13D illustrate another embodiment of a tip 1300 that can be used with a handpiece 10 of a skin treatment system. The tip 1300 can include the same or substantially the same features, components and/or other properties any other tip provided herein, unless otherwise elaborated. In some embodiments, one or more interior protruding features or members 1340 of the tip 1300 can be configured to divide the area prescribed by the peripheral lip 1330 into a series (e.g., 2, 3, 4, 5, 6, 7, 8, 9, 10, more than 10, etc.) of partitioned cells or zones 1341. As shown, such zones or cells 1341 can be joined or otherwise fluidly and/or otherwise coupled or connected using one or more cell connections 1344 and/or other fluidic features or components.

[0244] In some embodiments, when fluid enters the area prescribed by the peripheral lip 1330 (e.g., via one or more fluid inlet ports or openings 1350), it can fill or at least partially fill or occupy, at least temporarily, an inlet area or region 1335. From there, fluid can be transferred to one or more other portions of the tip (e.g., to, adjacent, between and/or otherwise near neighboring interior protruding features or members 1340) via cell connections 1344. Fluid can then move or otherwise be directed to (e.g., directly or indirectly) one or more adjacent cells or zones 1341, after which the fluid can leave the partitioned cells 1341 and/or other portions or areas of the distal end of the tip via one or more waste ports or openings 1322, similar to other embodiments disclosed herein (e.g., the tip of FIG. 12A).

[0245] In some embodiments, two or more of the cells or zones 1341 are connected by one or more cell connections or other fluidic passages 1344 (e.g., in such a way that the treatment fluid is dispersed through various areas surrounded and defined by the peripheral lip 1330). In some embodiments, the internal face features 1340 that define the partitioned cells 1341 and/or are otherwise positioned on the tip can contact the skin surface during a skin treatment procedure such that treatment fluid is prevented or substantially prevented from passing over the internal face features 1340. In some embodiments, the portions of the internal face features 1340 and peripheral lip 1330 that contact the skin surface can be configured to at least partially abrade skin. This can be accomplished, by way of example and without limitation, by having one or more sufficiently sharp edge or other features, the inclusion of abrasive features or materials, or otherwise as described herein, such that when the tip 1300 is advanced along the skin surface, at least a portion of the stratum comeum is removed from the skin during a skin treatment procedure.

EDGE.218WO -55- Knobbe, Martens, Olson & Bear, LLP [0246] The cell connections 1344 can be flush or generally flush with the tip base surface 1331 such that the fluid docs not need to change distal elevation to pass between the internal face features 1340. In other embodiments, in lieu of or in addition to having flush or substantially flush cell connections 1344, one or more cell connections 1344 can be non-flush (e.g., have some height) relative to the tip base surface 1331. Such an elevation change can impact (e.g., increase) the velocity of the fluid as it moves along the various surfaces of the tip (e.g., next to and/or between protruding internal members or features 1240. For any of the embodiments disclosed herein with cell connections or similar fluidic features or components 1344, such connections be at least partially arched or otherwise curved or rounded. Thus, in some embodiments, the distal-most surfaces of one or more cell connections 1344 are not aligned and/or parallel relative to the tip base surface 1331 of the tip. Such curved or arched surfaces for cell connections 1344 can additionally provide the benefit of directing the treatment fluid towards the treatment area of the subject, thereby increasing the efficacy of any treatment being performed.

[0247] A partitioned cell 1341 can have multiple (e.g., two or more) cell connections or other fluidic passages or features 1344. Such a configuration can provide one or more areas or regions of the tip (e.g., an area within one or more partitioned cells or zones 1341) with enhanced (e.g., increased, smoother, easier, etc.) fluid flow characteristics and properties. The fluid can exit or leave the area prescribed by the peripheral lip 1330 via one or more one or more waste or exit openings or ports 1322, which, in some arrangements, are located at least partially within an area prescribed or surrounded by a peripheral lip, an interior feature or member (e.g., a protruding member configured to abrade skin) 1340 and/or the like. The embodiment of the tip 1300 depicted in FIG. 13 A shows a tip 1300 with four openings 1322, located in cardinal directions of the area prescribed by the peripheral lip 1330. However, in other embodiments, the quantity, shape, size, location, distribution, orientation and/or other details regarding the waste ports or openings 1322 can vary, as desired or required.

[0248] As noted above with reference to FIGS. 11A to 11D and 12A to 12D, according to some embodiments, the distance between the tip base surface 1331 and the peripheral lip 1330 may vary for a particular tip. The height of the lip and/or interior features may vary to, for example, vary the height or distal extent of such members or features from

EDGE.218WO -56- Knobbe, Martens, Olson & Bear, LLP one cell or zone to the next, as desired or required. In other embodiments, such a distance is constant.

[0249] As depicted in FIG. 13D, the distance from a portion of the tip base surface 1331 and the peripheral lip 1330 is measured as 13hl at one of the one or more openings 1322, as 13h2 at the base of the partitioned cell 1341, as 13h3 at the apex of a cell connection 1344, and as 13h4 at the inlet area 1335. As noted above, such a height or distal extent difference can assist in moving fluids and/or other treatment materials across and/or along one or more portions of the tip 1300.

[0250] As noted above, the materials, sections, regions, portions, components and/or the like of the tip can include a uniform durometer or other measure of flexibility. For example, the various portions and components used for the tip can have a durometer that is equal or substantially equal. In other embodiments, one or more portions or sections can have a different durometer (or other measure of flexibility or rigidity), as desired or required. In some arrangements, by way of example, the peripheral lip is softer and more flexible than one or more other portions, components, members and/or regions of the tip (e.g., the interior protruding member(s), other abrasive features or members, the base, the proximal end that is configured to couple the handpiece to the tip, other portions of the tip’s main body portion, etc.), as desired or required. The tip 1300 can have several of, all of, or parts of its features made of a material with a higher or lower durometer than the durometer of surrounding features. In some embodiments, the tip 1300 comprises a singular material that has a consistent or uniform (or substantially consistent or uniform) durometer.

[0251] FIG. 13D schematically illustrates one embodiment of a possible or predicted flow pattern for fluid directed to the tip 1300 (e.g., from one or more inlet ports or openings 1350 to the one or more waste ports or openings 1322). After entering from a fluid inlet port 1350 and through or across one or more inlet areas or portions 1335, fluid can be directed radially outwardly (e.g., to or near one or more partitioned cells or zones 1341). According to one embodiment, when within a first cell, at least a portion of fluid can be divided or diverted (e.g., as denoted by diversion point 13D1) and can move radially outwardly (e.g., towards a second and/or other partitioned cell or zone 1341). Thus, at least a portion of fluid being moved can be combined, at least partially, with one or more other branches and/or sources of treatment fluid (e.g., as denoted in FIG. 13D by conversion point 13C1). In

EDGE.218WO -57- Knobbe, Martens, Olson & Bear, LLP situations where treatment fluid is combined with one or more other branches or sources of treatment fluid, fluid can be further divided or diverted (c.g., as denoted by diversion point 13D2) to be directed to one or more cell connections or other fluidic members, features or passages 1344, which can lead to area prescribed by the peripheral lip 1330 and/or internal walls 1342. Other flow path configurations can apply, as desired or required for a particular skin treatment procedure, based on, for example and without limitation, the configuration and number of areas defined by the internal wall 1342, the partitioned cells 1341, the cell connections 1344 within a tip 1300 and/or the like.

[0252] In some embodiments, the distal portion of the tip 1300 and the proximal portion of the tip 1300 can be formed of or can comprise a plurality (e.g., multiple) parts or portions, and can interface and/or interact to form a unitary part, like other tips disclosed herein. The two or more portions that form the tip 1300 can have different durometers, as described with other tips herein, to provide the tip 1300 with the benefits associated with having this multi-part configuration as described herein.

[0253] FIGS. 14A to 14D disclose another embodiment of a tip 1400 that is configured to be used with a handpiece 10 of a skin treatment device or system. As shown, the tip 1400 comprises interior member or features 1440 that include at least one internal bar 1442 and at least one internal stem 1444. In some embodiments, the proximal portion 1410 of the tip 1400 can be configured to connect the tip 1400 with a distal end 12 of a handpiece 10. In some arrangements, the internal face features 1440 of the tip 1400 can contact the skin surface during a skin treatment procedure such that treatment fluid is prevented or substantially prevented from passing over the internal bar 1442, internal stem 1444, or other internal face features 1440 during a skin treatment procedure. In some embodiments, the portions of the internal face features 1440 and peripheral lip 1430 that contact the skin surface can be configured to abrade the skin. This can be accomplished by, for example and without limitation, having a sufficiently sharp edge, the inclusion of abrasive features or materials, or otherwise as described herein, such that when the tip 1400 is advanced along the skin surface, at least a portion of the stratum comeum is removed from the skin during a skin treatment procedure.

[0254] In some embodiments, the distal portion 1432 of the tip 1400 can be arched or otherwise curved or non-linear. Such a configuration can follow or otherwise track contours

EDGE.218WO -58- Knobbe, Martens, Olson & Bear, LLP of the face or other portion of the subject’s body that will be treated. As a result, in some arrangements, the curved or non-linear configuration can provide a better temporary seal (e.g., more complete or thorough, more adaptive to changing curvature of the skin surface) during treatment for areas of the subject’s anatomy that may require more flexibility along the tip or distal end (e.g., skin surfaces with hair or a higher concentration of hair, such as, for example, cheeks, mouth, lip, chin and/or neck areas with facial hair, eyebrows, the scalp, etc., areas without defining bone structures such as the lips, other relatively contoured areas, etc.). In some embodiments, an arc representative of the tip’s curvature can be denoted by angle a. In some examples, the angle a is 50 to 60 degrees (e.g., 50 to 51, 51 to 52, 52 to 53, 53 to 54, 54 to 55, 55 to 56, 56 to 57, 57 to 58, 58 to 59, 59 to 60 degrees, angles between the foregoing ranges, etc.). In other embodiments, the angle a is less than 50 degrees or greater than 60 degrees, as desired or required. The angle a combined with the durometer of the distal portion 1432 of the tip 1400 allows for a wide range of applications for different treatment areas.

[0255] With reference to the tip embodiment 1400 of FIGS. 14A to 14D, in addition to having a non-planar (e.g., convex or concave) distal end portion that is configured to contact skin, the tip 1400 can be resiliently biased so that when the tip is placed along a targeted skin surface with a specific force, the curved shape and be flattened or substantially flattened (e.g., made less curved or rounded) to conform with the curvature of the targeted skin surface. In some embodiments, with sufficient force placed on the tip (e.g., as a result of pressing the tip against a subject’s skin surface), the tip 1400 can assume a flat or substantially flat or planar shape, at least temporarily. As the tip is advanced along the skin surface, if the curvature or geometry of the treatment area varies, the tip can deform to suit the changing geometry to maintain or substantially maintain the temporary seal formed by the peripheral lip 1430 against the skin surface. Once an aesthetician or other user reduces the force on the tip (e.g., by moving the tip away from a subject’s skin), the tip can once again assume the curved (e.g., convex or concave, non-planar, etc.) shape. The resiliency in the tip can be attributed to the materials used (e.g., elastomeric or other polymeric or plastic materials), the flexibility of any materials and/or portions and/or the like.

[0256] With continued reference to FIGS. 14A to 14D, in some embodiments, when fluid enters the area prescribed or surrounded by the peripheral lip 1430 (e.g., via one or more fluid inlet ports or opening 1450), it can pass over or along one or more areas or portions

EDGE.218WO -59- Knobbe, Martens, Olson & Bear, LLP of the tip base surface 1431 (e.g., along the peripheral lip 1430 and the internal bar 1442). In some embodiments, the internal face features 1440 can at least partially define or substantially define a flow path of the treatment material as it progresses through the area defined by the peripheral lip 1430. In some embodiments, at least some of the fluid can pass around, near or along a portion (e.g., an end) of the internal bar 1442. In some embodiments, fluid can then be divided and/or diverted such that at least a portion of the fluid passes through one or more internal stems 1444 until finally reaching one or more waste ports or openings 1422.

[0257] As noted above, according to some embodiments, the use of lower- durometer polymers and/or other configurations that enhance conformity and/or flexibility can provide a beneficial resiliency for scalp and sensitive areas. However, certain features of the tip, including the mounting to the handpiece, may require a rigid (e.g., or at least a more rigid) structure or configuration (e.g., to maintain a reliable fixation with the handpiece to which the tip removably secures). As such, the tip 1400 can include a multi-durometer construction (and/or other construction where flexibility and/or rigidity along the tip can be advantageously and strategically varied). In some embodiments, this can permit one or more portions or areas of a tip to be manufactured (e.g., molded) using one or more low-durometer polymers, while other portion of the tip (e.g., the tip-to-handpiece connection) are manufactured (e.g., molded) using one or more materials having a higher durometer and/or a greater rigidity. The combination of these dissimilar materials can be achieved by various manufacturing methods, such as, by way of example and without limitation, a two-shot molding process, insert molding, dual-durometer additive manufacturing, simple post-assembly of separate parts and/or the like. In some embodiments, portions of or all of the internal face feature 1440 can have a durometer that is higher than the durometer of adjacent portions of the tip 1400. In some embodiments, other portions of the tip 1400 can have a different durometer than the remainder of the tip, as desired or required. In some embodiments, the tip 1400 can have more than two regions (e.g., three, four, five, more than five) of distinct durometer.

[0258] According to some embodiments, one or more interior members or features (e.g., protruding members, recesses, etc.) 1440 of a tip 1400 can include at least partially rounded or curved surfaces where they contact the skin of the subject. However, in other arrangements, the members or features 1440 can have non-rounded or non-curved surfaces or features (e.g., sharp or sharper edges defined by a non-rounded angle), either in addition to or

EDGE.218WO -60- Knobbe, Martens, Olson & Bear, LLP in lieu of any rounded or curved features or members. In some embodiments, these internal stems 1444 can assist in abrading a surface of the skin as the tip 1400 is advanced or otherwise moved relative to a skin surface. In some arrangements, rounding the contact surface of these internal face features 1440 can enhance fluid delivery and/or distribution (e.g., greater coverage, more even or uniform spreading or dispersal, etc.) of fluids along the tip and the skin surface being treated by directing treatment fluid into the skin surface as the tip is advanced along the skin surface. This can advantageously increase or otherwise enhance the efficacy of a treatment procedure. The embodiment of the tip 1400 depicted in FIG. 14A shows a tip 1400 with only one opening 1422, but more than one opening can be used.

[0259] As noted above with reference to other tip arrangements herein, according to some embodiments, the distance between the tip base surface 1431 and the peripheral lip 1230 may vary for a particular tip. The height of the lip and/or interior features may vary to, for example, vary the height or distal extent of such members or features from one cell or zone to the next, as desired or required. In other embodiments, such a distance is constant.

[0260] In some embodiments, the tip illustrated in FIGS. 14A to 14D (e.g., as a result of, at least in part, the design of the multiple surface areas and edges of tip 1400 which contact a treatment area of a subject) can facilitate the tip’s exfoliating and cleansing properties, aid in removing sebum, blackheads and/or other undesired materials from the subject’s the skin, and provide other benefits as described herein.

[0261] As noted above, the materials, sections, regions, portions, components and/or the like of the tip can include a uniform durometer or other measure of flexibility. For example, the various portions and components used for the tip can have a durometer that is equal or substantially equal. In other embodiments, one or more portions or sections can have a different durometer (or other measure of flexibility or rigidity), as desired or required. In some arrangements, by way of example, the peripheral lip is softer and more flexible than one or more other portions, components, members and/or regions of the tip (e.g., the interior protruding member(s), other abrasive features or members, the base, the proximal end that is configured to couple the handpiece to the tip, other portions of the tip’s main body portion, etc.), as desired or required. The tip 1400 can have several of, all of, or parts of its features made of a material with a higher or lower durometer than the durometer of surrounding

EDGE.218WO -61- Knobbe, Martens, Olson & Bear, LLP features. In some embodiments, the tip 1400 comprises a singular material that has a consistent or uniform (or substantially consistent or uniform) durometer.

[0262] FIG. 14D illustrates one embodiment of a possible or predicted flow pattern for fluid being directed to the tip 1400 (e.g., fluid passing from one or more fluid inlet ports or openings 1450 to one or more waste ports or openings 1422). As shown, in one embodiment, after entering from a fluid inlet port 1450, at least a portion of the fluid can be directed by the one or more internal face features 1440, such as an internal bar 1442. The fluid can first be directed radially outwardly (e.g., into, to and/or near one or more areas bordered by the peripheral lip 1430 and the internal bar 1442, any other location or region of the tip, etc.) from the fluid inlet port 1450. As the fluid passes around the internal bar 1442, the fluid can be divided and/or diverted as it passes around and/or through the various internal stems 1444. In some embodiments, such a split or other directional change can occur two or more times (e.g., causing fluid to pass around or near the multiple internal stems 1444 and ultimately exiting the area prescribed by the peripheral lip 1430 via one or more waste ports or openings 1422). According to some embodiments, other flow path configurations can apply, as desired or required for a particular skin treatment procedure, based on the configuration and number of areas defined by the internal face features 1440, the internal bar 1442, and the internal stems 1444 of the tip 1400.

[0263] In some embodiments, the distal portion of the tip 1400 and the proximal portion of the tip 1400 can be formed of or can comprise a plurality (e.g., multiple) parts or portions, and can interface and/or interact to form a unitary part, like other tips disclosed herein. For example, in some embodiments, the two or more portions that form the tip 1400 can have different durometers, as described with reference to other tips disclosed and described herein. This can, in certain arrangements, provide the tip 1400 with the benefits associated with having this multi-part configuration as described herein. In some embodiments, treatment fluid can enter the area defined by the peripheral lip, be directed through the area defined by the peripheral lip by the one or more internal face features that contact the skin surface and form a fluid flow path, and be drained from the tip by an opening to be drawn by a vacuum source attached to the handpiece 10 connected to the tip 1400.

[0264] In some embodiments, as illustrated in FIGS. 15A and 15B, a tip 1500, as discussed herein with respect to other tips, can include a proximal core 1560 made of a material

EDGE.218WO -62- Knobbe, Martens, Olson & Bear, LLP with a durometer low enough to allow it to pass through the rigid distal end 12 of the handpiece 10. The interference fit by the proximal core 1560 is created by passing the smaller radius 1564 through the hole through the distal end 12 of the handpiece 10 until the proximal core 1560 passes far enough to have the larger radius 1562 pass through the lumen of the distal end 12 of the handpiece 10. At this point, the tip 1500 contacts the distal end 12 of the handpiece 10 by the handpiece interaction point 1566 and the distal end of the core’s larger radius 1562. Due to the core’s larger radius 1562 being larger than the diameter of the opening in the distal end 12 of the handpiece 10, the tip 1500 is removably attached to the handpiece 10.

[0265] The tip 1500 can have several of, all of, or parts of its features made of a material with a higher or lower durometer than the durometer of surrounding features. The tip 1500 can also be comprised of a singular material that has a consistent durometer.

[0266] The tip 1500 is depicted in FIGS. 15A and 15B as a cross-sectional view. In some embodiments, the tip 1500 can be formed as one piece and inserted into the distal end 12 of the handpiece 10 as described herein. In some embodiments, the tip 1500 can have a size and shape similar to tip 1400 as described herein.

[0267] According to some arrangements, the tip 1500 can include one or more features that are similar or substantially similar to features included in other tips disclosed and/or referenced herein. For example, the tip can include a distal end configured to contact the skin during a skin treatment procedure, a peripheral lip configured to form at least temporary seal with a skin surface during a skin treatment procedure and an internal face feature configured to direct the flow of treatment fluid across the area defined by the peripheral lip.

[0268] In some embodiments, one or more features of the tip 1500 can be configured to at least partially abrade skin tissue as the tip 1500 is advanced along a targeted skin surface. In some embodiments, the peripheral lip and/or one or more internal face features of the tip 1500 can be configured to at least partially abrade skin and remove at least a portion of the stratum corneum as the tip is advanced along (e.g., translated or otherwise moved relative to) the skin surface. The system and related method can be configured such that treatment fluid can enter the area defined by the peripheral lip, be directed through the area defined by the peripheral lip (e.g., with the help or guidance of one or more internal face features that contact the skin surface and form a fluid flow path), and be drained or removed from the tip

EDGE.218WO -63- Knobbe, Martens, Olson & Bear, LLP via one or more openings (e.g., drawn by a vacuum source attached to the handpiece 10 connected to the tip 1500, via gravity, etc.).

[0269] FIGS. 16A through 16C depicts an alternative embodiment of a tip (e.g., a modular tip) 1600, comprising two or more distinct parts, such as, for example and without limitation, an internal component 1660 and an external component 1670. In some embodiments, a tip with some components which have higher durometers and some components which have lower durometers can increases its effectiveness of a skin treatment procedure using the skin (e.g., increasing the tip’s 100 abrasion ability, increasing the tip’s 100 resistance to collapsing under vacuum pressure, allowing, for example and without limitation, the tip to specifically deform to conform to a skin surface as the tip is advanced along the skin surface, etc.). Such a multi-durometer tip concept can be applied to any of the tip embodiments disclosed herein.

[0270] FIG. 16B depicts the modular tip 1600 in a partially disassembled state, where the internal component 1660 and the external component 1670 are separated. Advantageously, in some embodiments, the internal component 1660 and the external component 1670 can interface by deforming retention nodules 1672 on the external component 1670 to fit within corresponding retention nodes 1662 in the internal component 1660. While in its configured or assembled state where the internal component 1660 interlocks with the external component 1670, the modular tip 1600 as a whole is substantially similar to the tip 100 of FIG. 2A and/or other tip embodiments disclosed herein or related versions thereof, except as may be otherwise elaborated.

[0271] The tip 1600 can have features substantially similar to features presented by other tips herein, such as a distal end configured to contact the skin during a skin treatment procedure, a peripheral lip configured to form an at least temporary seal with a skin surface during a skin treatment procedure, an internal face feature configured to direct the flow of treatment fluid across the area defined by the peripheral lip and/or the like.

[0272] In some embodiments, one or more features of the tip 1600 can be configured to abrade the skin as the tip 1600 is advanced along (e.g., translated or otherwise moved relative to) the skin surface. In some embodiments, the peripheral member or lip and/or one or more internal face features of the tip 1600 can be configured to at least partially abrade the skin and remove at least a portion of the stratum corneum as the tip is advanced along the

EDGE.218WO -64- Knobbe, Martens, Olson & Bear, LLP skin surface. Tn some embodiments, the system is configured to deliver treatment fluid and/or other material from a fluid source (e.g., bottle, vial and/or other container placed in fluid communication with the system) through an opening 122 in a fluid connector 120, into the area defined by the peripheral lip, be directed through the area defined by the peripheral lip by the one or more internal face features that contact the skin surface and form a fluid flow path, and be drained or removed from the tip via one or more openings (e.g., ports). In some embodiments, this is accomplished with the assistance of a vacuum or suction force that is generated along the tip using a vacuum source placed in fluid communication with the handpiece 10 and the modular tip 1600 (e.g., via one or more vacuum ports or openings 24).

[0273] FIG. 17 depicts an alternative embodiment of the modular tip depicted in FIGS. 16A and 16B. As shown, the tip 1700 can comprise one or more abrasive features and/or elements 1748 at, near and/or along its internal face feature 1740. The abrasive feature 1748 can use any of the other abrasive features disclosed herein. Such abrasive features or members 1748 can include, without limitation, abrasive materials (e.g., sand or sandy, grit or gritty materials, materials with sharp or substantially sharp edges, other coarse materials, etc.), abrasive features (e.g., geometric shapes or features), ridges, protrusions, and/or other features as described herein. Abrasive features or members 1748 can be secured to the tip (e.g., a spiral or other protruding interior member or element 1740, the peripheral lip, the base, etc.) in any one of a variety of methods or technologies (e.g., using adhesives, incorporating such features during the manufacture of the tip, other pre or post tip fabrication methods or steps, etc.). In some embodiments, the abrasive features 1748 can be arranged along a peripheral lip of the modular tip 1700, or on other features configured to contact the skin surface as the modular tip 1700 is advanced along the skin surface.

[0274] FIG. 18 depicts an alternative embodiment of a tip 1800 which is substantially similar in design, unless otherwise elaborated, to the tip 1400 of FIGS. 14A through 14D, to be used with the handpiece 10 described herein. The tip 1800 has a flexible distal portion 1832. In some embodiments, fluid can enter the peripheral lip 1830 by via one or more fluid inlet ports or openings 1850. In some embodiments, fluid can then be divided and/or diverted such that at least a portion of the fluid passes through one or more internal stems 1844 until finally reaching one or more waste ports or openings 1822. The internal stems 1844 which are dispersed in the area prescribed by the peripheral lip 1830 can be composed of

EDGE.218WO -65- Knobbe, Martens, Olson & Bear, LLP a more durable material with a higher thermal conductivity than surrounding materials, such that during use the internal stems 1844 can provide a cooling effect to the treated tissue as the tip 1800 passes over the skin of the subject, where the heat can then be transferred away by the treatment fluid passing around the internal stems 1844. The internal bar 1842 may also be formed of the material with higher thermal conductivity to increase the cooling effect. These thermally conductive internal features can be applied to and incorporated within any other tip embodiments as described herein or variations thereof.

[0275] In some embodiments, use of these thermally conductive internal face features can also advantageously benefit the abrasive qualities of any tip utilizing the thermally conductive internal face features. In some embodiments, the thermally conductive internal face features comprise sharp portions or features designed to contact the skin surface, such that the thermally conductive internal face features scrape or abrade at least a portion of the stratum comeum of the skin surface being treated, while also applying a cooling effect to the skin surface. The thermally conductive internal face features can be cooled by a treatment fluid that passes through the area defined by the peripheral lip. Advantageously, cooling the skin surface with the thermally conductive internal face features can increase the efficacy of a treatment procedure, reduce inflammation or soothe the affected treatment area, reduce redness associated with abrasion of the stratum corneum, and other benefits as described herein.

[0276] FIGS. 19A and 19B illustrate two additional embodiments of a tip 1900 having one or more flexible and/or other non-rigid portions or components. As shown, the tips 1900 can include a plurality of knubs or other protruding members 1940. The size (e.g., diameter or other cross-sectional dimension, width, height, thickness, etc.), shape, density, distribution and/or other details of the knubs or other protruding members 1940 can be customized, as desired or required.

[0277] In some embodiments, the use of knubs or similar members can provide one or more benefits to the tip and the treatment for which the tip will be used, including, for example and without limitation, providing enhanced cleansing and/or extraction during a procedure, providing a massaging effect or massaging action and/or other agitation to the skin, promoting deeper penetration of any fluids and/or other treatment materials that are delivered to the skin tissue, creating a pleasant feel to the subject and/or the like.

EDGE.218WO -66- Knobbe, Martens, Olson & Bear, LLP [0278] The knubs or similar members or features 1940 can include one or more flexible or partially flexible elastomeric and/or polymeric materials (e.g., rubber). In some embodiments, the knubs or other members 1940 are positioned entirely within a peripheral lip 1930 of the tip 1900. However, in other embodiments, at least one or more of the knubs 1930 can be positioned radially outside of a peripheral lip 1930. In some embodiments, the knubs 1940 are spaced and/or otherwise oriented and configured to permit fluid pass between adjacent knubs 1940. However, in some embodiments, the spacing of the knubs can be changed to reduce or eliminate flow of fluids between such knubs, as desired or required.

[0279] Further, as discussed with reference to other embodiments herein, the peripheral lip 1930 of the tip 1900 can be at least partially flexible (e.g., as a result of the material(s) used, its shape and configuration, etc.) to at least partially conform to a surface of a skin during a treatment procedure. In some embodiments, the peripheral lip 1930 is flexible. The flexibility of the peripheral lip 1930 can be equal or substantially equal to the flexibility of the knubs or other elements or members located within an interior region surrounded by the lip. However, in other embodiments, as noted herein, the peripheral lip can be more flexible (e.g., less rigid) than surrounding portions of the tip (e.g., the knubs 1940, the proximal portion 1910 of the tip, etc.). This can permit the peripheral lip to more easily and reliably conform to a subject’s skin surface during use, which may assist in creating and maintaining a temporary seal between the lip 1930 and the targeted skin surface. In some embodiments, the tip 1900 is configured to connect or secure to a handpiece 10 at its proximal portion 1910 similar to other tips disclosed herein. The tip 1900 can have a relatively circular or oval distal portion 1932. The protruding members 1940 can be surrounded or substantially surrounded by a peripheral lip 1930. In some embodiments, the peripheral lip 1930 can prevent or substantially prevent treatment fluid from escaping the area immediately surrounding the distal portion 1932 of the tip 1900.

[0280] In some embodiments, one or more features of the tip 1900 can be configured to abrade the skin as the tip 1900 is advanced along the skin surface (e.g., translated or otherwise moved (e.g., laterally) relative to the skin surface). In some embodiments, the peripheral lip and/or one or more internal face features of the tip 1900 can be configured to at least partially abrade the skin and remove at least a portion of the stratum corneum as the tip is advanced along the skin surface. In some embodiments, treatment fluid and/or other

EDGE.218WO -67- Knobbe, Martens, Olson & Bear, LLP materials can be delivered or otherwise transferred (e.g., drawn) to the area defined by the peripheral lip, be directed through the area defined by the peripheral lip by the one or more internal face features that contact the skin surface and form a fluid flow path, and be removed from the tip via one or more openings (e.g., waste opening). In some arrangements, this process is facilitated by activation of a vacuum source attached to the handpiece 10 in fluid communication with the modular tip 1900 by a vacuum port or opening.

[0281] An example cross-sectional view of a tip 1900, 2000 having a plurality of knubs or similar member or features 1940, 2040 is schematically illustrated in FIG. 20. As shown, the tip can include one or more inlet and/or waste ports or openings 24 through which fluids and/or other treatment materials can be directed to the tip. As shown, the knubs or other members 1940, 2040 have distal ends that are recessed relative to the peripheral lip 2032. However, in other embodiments, the distal end or extent of the knubs 1940, 2040 can extend to the same or greater distance distally relative to the lip 2032, as desired or required. In some embodiments, one or more cross-members or struts 2031 can be used to connect two or more of the knubs or similar members or features. This can provide a greater amount of stability (e.g., less flexibility) to the knubs and the overall tip design. The tip 2000 can secure to the distal end 12 of the handpiece 10 (e.g., along its proximal portion 2014, which can function similarly or substantially similarly to other proximal portions of dips disclosed herein). Similarly, the tip 2000 can include a waste suction collection region 2026 substantially similar to other waste collection regions described herein, the region designed to receive waste fluid drawn from the distal end of the tip through the one or more vacuum openings 2054.

[0282] Certain embodiments can be specialized for application to a specific portion of the skin of the subject. For example, skin close to the hairline or within the scalp is less soft-conformal than facial and body skin, and a tip must address additional obstacles such as hair that may impede the ability to form a seal with the skin of the subject for the tip to be effective. As such, certain modifications can be made to a tip 100 to increase its efficacy, such as lowering amount of the interior area occupied by internal face features 140, narrowing the overall size or modifying the shape of the peripheral lip 132 to increase sealing at the contact area, increasing the cross-sectional area of the vacuum or suction ports or openings 154 to allow flow to continue even with the presence of some hair, or further adding a mesh or other permeable barrier at the vacuum or suction ports or openings 154 to prevent hair from entering

EDGE.218WO -68- Knobbe, Martens, Olson & Bear, LLP the waste suction collection region 126. Additionally, flow rates of the treatment fluid could be reduced by increasing cross-sectional area of the fluid flow channels by spacing out the internal face features 140 within the perimeter of the peripheral lip 132. Alternative methods to increase the efficacy of forming a seal on the scalp which would be known by one skilled in the art may be made without departing from the spirit and scope of the invention and without diminishing its attendant advantages.

[0283] Certain embodiments disclosed herein (or equivalents or related versions thereof) can be customized for application to a specific portion of the skin of the subject. For example, the skin surface along the back of the subject is typically more resistive to abrasion and generally thicker than the skin of the face of a subject, and must deal with additional obstacles such as body hair, which is more coarse than hairs on the face of the skin and may impede the ability to form a seal with the skin of the subject for the tip to be effective. As such, certain modifications can be made to the tip 100 to increase its efficacy and performance. For example, the abrasive nature of the tip 100 can be increased or improved, the width of the distal portion of the tip relative to its height can be increased to decrease the number of strokes necessary to cover the larger surface area of the subject, one or more additional members or features (e.g., rigid and/or semi-rigid members or features) can be incorporated into the peripheral lip 132 or internal face features 140 to provide a more rigid platform for an abrasive feature 148 and/or the like. Alternative methods to increase the efficacy of forming a seal on the back of the subject which would be known by one skilled in the art may be made without departing from the spirit and scope of the invention and without diminishing its attendant advantages.

[0284] Certain embodiments can be specialized for application to a specific portion of the skin of the subject. For example, the skin of the lips of the subject is much more sensitive than and has many more contours than the other skin of the face of the subject and can lead to the digestive tract of the subject. As such, certain modifications can be made to the tip 100 to more suit its purpose, such as decreasing any abrasive nature of the tip 100, increasing the disparity of heights between the internal face features 140 and the peripheral lip 132 such that a seal is more likely to be made, change the profile of the peripheral lip 132 to more conform with the general shape of lips, or increase the deformability of the internal face features 140 or peripheral lip 132. Alternative methods to increase the efficacy of forming a seal on the lips

EDGE.218WO -69- Knobbe, Martens, Olson & Bear, LLP of the subject which would be known by one skilled in the art may be made without departing from the spirit and scope of the invention and without diminishing its attendant advantages.

[0285] Although several embodiments and examples are disclosed herein, the present application extends beyond the specifically disclosed embodiments to other alternative embodiments and/or uses of the inventions and modifications and equivalents thereof. It is also contemplated that various combinations or sub-combinations of the specific features and aspects of the embodiments may be made and still fall within the scope of the inventions. Accordingly, it should be understood that various features and aspects of the disclosed embodiments can be combined with or substituted for one another in order to form varying modes of the disclosed inventions. Thus, it is intended that the scope of the present inventions disclosed herein should not be limited by the particular disclosed embodiments described above but should be determined only by a fair reading of the claims that follow.

[0286] While the inventions are susceptible to various modifications, and alternative forms, specific examples thereof have been shown in the drawings and are herein described in detail. It should be understood, however, that the inventions are not to be limited to the particular forms or methods disclosed, but, to the contrary, the inventions are to cover all modifications, equivalents, and alternatives falling within the spirit and scope of the various embodiments described and the appended claims. Any methods disclosed herein need not be performed in the order recited. The methods summarized above and set forth in further detail below describe certain actions taken by a practitioner; however, it should be understood that they can also include the instruction of those actions by another party. The methods summarized above and set forth in further detail below describe certain actions taken by a user (e.g., a professional in some instances); however, it should be understood that they can also include the instruction of those actions by another party. Thus, actions such as “moving a handpiece” or “delivering a fluid” include “instructing moving a handpiece” and “instructing delivering a fluid.” The ranges disclosed herein also encompass any and all overlap, subranges, and combinations thereof. Language such as “up to,” “at least,” “greater than,” “less than,” “between,” and the like includes the number recited. Numbers proceeded by a term such as “about” or “approximately” include the recited numbers. For example, “about 10 mm” includes “10 mm.” Terms or phrases preceded by a term such as “substantially” include the recited term or phrase. For example, “substantially parallel” includes “parallel.”

EDGE.218WO -70- Knobbe, Martens, Olson & Bear, LLP

Claims

1. A tip for a skin treatment device, the tip comprising: a peripheral member located along a distal end of the tip, wherein the peripheral member is configured to contact a skin surface when the tip is secured to an end of the skin treatment device; wherein the peripheral member defines an interior area or region along the distal end of the tip; at least one interior member at least partially positioned within the interior area or region defined by the peripheral member; wherein the at least one interior member extends from a base distally in a direction of the distal end; wherein the peripheral member has a flexibility that is greater than a flexibility of the at least one interior member; and wherein the peripheral member is configured to at least partially conform to skin surface being treated during use; at least one fluid delivery port or opening in fluid communication with the interior area or region, the at least one fluid delivery port or opening configured to direct a treatment material to the interior area or region during use; and at least one waste port or opening in fluid communication with the interior area or region, the at least one waste port or opening configured to transfer waste away from the interior area or region during use.

2. The tip of Claim 1, wherein a durometer of the peripheral member is lower than a durometer of the at least one interior member or feature; wherein the at least one interior member comprises at least one protruding member; and wherein the tip comprises a distal portion and a proximal portion, wherein the distal portion comprises the peripheral member and the at least one interior member, and wherein the proximal portion is configured to contact and secure to an end of the skin treatment device.

EDGE.218WO -71- Knobbe, Martens, Olson & Bear, LLP

3. The tip of Claim 1 , wherein a durometer of the peripheral member is lower than a durometer of the at least one interior member or feature.

4. The tip of Claim 1, wherein the at least one interior member comprises at least one protruding member.

5. The tip of Claim 1, wherein the at least one interior member comprises a member having a spiral or curved shape.

6. The tip of Claim 1, wherein the tip comprises a distal portion and a proximal portion, wherein the distal portion comprises the peripheral member and the at least one interior member, and wherein the proximal portion is configured to contact and secure to an end of the skin treatment device.

7. The tip of Claim 6, wherein the proximal portion is secured to the distal portion of the tip during a friction fit or press fit connection.

8. The tip of Claim 6, wherein the proximal portion is secured to the distal portion of the tip using at least one of an adhesive, a mechanical connection, a threaded connection and/or any other connection or coupling method or technology.

9. The tip of Claim 1, wherein each of the peripheral member and the at least one interior member comprises a flexible configuration.

10. The tip of Claim 1, wherein the peripheral member comprises an elastomeric or other flexible polymeric material.

11. The tip of Claim 1 , wherein at least a portion of the at least one interior member comprises an abrasive material or feature.

12. The tip of Claim 11 , wherein the abrasive material or feature is positioned along a distal surface of the at least one interior member.

13. The tip of Claim 11, wherein the abrasive material or feature is impregnated or otherwise embedded within at least a portion of the at least one interior member.

14. The tip of Claim 1, wherein the peripheral member extends more distally relative to a distal-most end of the at least one interior member.

15. The tip of Claim 1, wherein the at least one interior member extends to or substantially to a distal end of the peripheral member.

EDGE.218WO -72- Knobbe, Martens, Olson & Bear, LLP

16. The tip of Claim 1 , wherein a distal end of the peripheral member is angled relative to both a longitudinal axis of the tip and an axis perpendicular to the longitudinal axis of the tip.

17. The tip of Claim 16, wherein the angled distal end of the peripheral member enhances the flexibility of the peripheral member and an ability of the peripheral member to at least partially conform to a skin surface being treated during use.

18. The tip of Claim 1, wherein at least a portion of the at least one interior member is configured to abrade or exfoliate skin tissue when the tip is moved relative to said skin tissue during use.

19. The tip of Claim 1, wherein at least a portion of the at least one interior member is not configured to abrade or exfoliate skin tissue when the tip is moved relative to said skin tissue during use.

20. The tip of Claim 1, wherein at least a portion of the at least one interior member comprises at least one knub or other member or feature configured to provide a massaging effect on skin tissue being treated during use.

21. The tip of Claim 1, wherein the tip is configured to be used in a microdermabrasion procedure.

22. The tip of Claim 1, wherein a plane or face formed along a distal-most plane or face of the tip is angled relative to both a longitudinal axis of the tip and an axis perpendicular to the longitudinal axis of the tip.

23. The tip of Claim 1, wherein the at least one interior member comprises an edge or another surface that is configured to at least partially abrade or exfoliate skin tissue when the tip is moved relative to said skin tissue during use.

24. The tip of Claim 1, wherein the tip is configured to be removably secured to an end of the skin treatment device.

25. The tip of Claim 1, wherein the tip is disposable.

26. The tip of Claim 1, wherein the skin treatment device comprises a handpiece or other handheld device.

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27. A tip for a skin treatment device, the tip comprising: a peripheral member located along a distal end of the tip, wherein the peripheral member is configured to contact a skin surface when the tip is secured to an end of the skin treatment device; at least one interior member at least partially positioned within an interior area or region defined by the peripheral member; wherein the peripheral member has a flexibility that is greater than a flexibility of the at least one interior member; and at least one fluid delivery port or opening in fluid communication with the interior area or region, the at least one fluid delivery port or opening configured to direct a treatment material to the interior area or region during use.

28. A skin treatment system, wherein the skin treatment system comprises a skin treatment handpiece and a tip according to Claim 1.

29. A skin treatment system, wherein the skin treatment system comprises a skin treatment handpiece and a tip according to Claim 27.

30. A skin treatment system, wherein the skin treatment system comprises a skin treatment handpiece and a tip according to any one of Claims 1 to 27.

31. The skin treatment system of Claim 28 or 29, wherein the skin treatment system comprises a microdermabrasion system.

32. A skin treatment system, the system comprising: a handpiece configured to be grasped and manipulated by a user; and a tip according to any of Claims 1 to 27, wherein the tip is configured to be removably secured to a distal end of the handpiece.

33. A skin treatment system, the system comprising: a handpiece configured to be grasped and manipulated by a user; and a tip according to Claim 1, wherein the tip is configured to be removably secured to a distal end of the handpiece.

34. The system of Claim 33, further comprising: at least one treatment material source; and a vacuum source;

EDGE.218WO -74- Knobbe, Martens, Olson & Bear, LLP wherein the system is configured to deliver at least one treatment material from the at least one treatment material source to the tip; and wherein the system is configured to transfer waste from the tip to a waste container with assistance of a suction or vacuum generated along the tip by the vacuum source.

35. The system of Claim 34, wherein the at least one treatment material source comprises a container configured to be secured to the handpiece.

36. The system of Claim 34, wherein the at least one treatment material source comprises a container configured to be secured to a manifold or other fluid distribution member of the system.

37. A skin treatment system, the system comprising: a handpiece configured to be grasped and manipulated by a user; and a tip for a skin treatment device, the tip comprising: a peripheral member located along a distal end of the tip, wherein the peripheral member is configured to contact a skin surface when the tip is secured to an end of the skin treatment device; at least one interior member at least partially positioned within an interior area or region defined by the peripheral member; wherein the peripheral member has a flexibility that is greater than a flexibility of the at least one interior member; and at least one fluid delivery port or opening in fluid communication with the interior area or region, the at least one fluid delivery port or opening configured to direct a treatment material to the interior area or region during use.

38. The system of Claim 37, further comprising: at least one treatment material source; and a vacuum source; wherein the system is configured to deliver at least one treatment material from the at least one treatment material source to the tip; and

EDGE.218WO -75- Knobbe, Martens, Olson & Bear, LLP wherein the system is configured to transfer waste from the tip to a waste container with assistance of a suction or vacuum generated along the tip by the vacuum source.

39. The system of Claim 38, wherein the at least one treatment material source comprises a container configured to be secured to the handpiece.

40. The system of Claim 38, wherein the at least one treatment material source comprises a container configured to be secured to a manifold system of the system.

41. A method for treating skin, the method comprising: positioning a distal end of a skin treatment device along a targeted skin surface; wherein the skin treatment device comprises a handpiece configured to be grasped and manipulated by a user; wherein the skin treatment device further comprises a tip secured to the handpiece; wherein the tip comprises a peripheral member located along a distal end of the tip, wherein the peripheral member is configured to contact the targeted skin surface during use; wherein at least one interior member is at least partially positioned within an interior area or region defined by the peripheral member; wherein the peripheral member has a flexibility that is greater than a flexibility of the at least one interior member; and wherein the skin treatment device is configured to deliver a treatment material to the interior area or region of the tip during use; and moving the skin treatment device along the targeted skin surface to perform a desired skin treatment.

42. The method of Claim 41 : further comprising generating a vacuum or suction force along the interior area or region, wherein generating the vacuum or suction force along the interior area or region comprises activating a vacuum source that is in fluid communication with the handpiece;

EDGE.218WO -76- Knobbe, Martens, Olson & Bear, LLP wherein contacting the skin surface comprises at least partially deforming the peripheral member so that the peripheral member at least partially conforms to the targeted skin surface; wherein a durometer of the peripheral member is lower than a durometer of the at least one interior member or feature; and wherein the at least one interior member comprises at least one protruding member.

43. The method of Claim 41, further comprising generating a vacuum or suction force along the interior area or region.

44. The method of Claim 43, wherein generating the vacuum or suction force along the interior area or region comprises activating a vacuum source that is in fluid communication with the handpiece.

45. The method of Claim 44, wherein the vacuum source comprises a vacuum pump.

46. The method of Claim 41, wherein positioning the distal end of the skin treatment device along the targeted skin surface comprises contacting the skin surface with the peripheral member of the tip.

47. The method of Claim 46, wherein contacting the skin surface comprises at least partially deforming the peripheral member so that the peripheral member at least partially conforms to the targeted skin surface.

48. The method of Claim 41, wherein a durometer of the peripheral member is lower than a durometer of the at least one interior member or feature.

49. The method of Claim 41, wherein the at least one interior member comprises at least one protruding member.

50. The method of Claim 41, wherein the at least one interior member comprises a member having a spiral or curved shape.

51. The method of Claim 41, wherein each of the peripheral member and the at least one interior member is at least partially flexible or comprises a flexible configuration.

52. The method of Claim 41, wherein the peripheral member comprises at least one elastomeric or other flexible polymeric material.

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53. The method of Claim 41 , wherein at least a portion of the at least one interior member comprises an abrasive material or feature.

54. The method of Claim 53, wherein the abrasive material or feature is positioned along a distal surface of the at least one interior member.

55. The method of Claim 53, wherein the abrasive material or feature is impregnated or otherwise embedded within at least a portion of the at least one interior member.

56. The method of Claim 41, wherein the peripheral member extends more distally relative to a distal-most end of the at least one interior member.

57. The method of Claim 41, wherein the at least one interior member extends to or substantially to a distal end of the peripheral member.

58. The method of Claim 41, wherein at least a portion of the at least one interior member is configured to abrade or exfoliate skin tissue when the tip is moved relative to said skin tissue during use.

59. The method of Claim 41, wherein at least a portion of the at least one interior member is not configured to abrade or exfoliate skin tissue when the tip is moved relative to said skin tissue during use.

60. The method of Claim 41, wherein at least a portion of the at least one interior member comprises at least one knub or other member or feature configured to provide a massaging effect on skin tissue being treated during use.

61. A tip configured to be secured to a distal end of a handpiece of a skin treatment system, the tip comprising: a distal portion configured to contact skin and a proximal portion configured to secure to a handpiece; a peripheral lip extending to the distal end, the peripheral lip defining an interior area; at least one fluid delivery opening located within the interior area and configured to deliver a treatment fluid to the interior area during use; at least one waste opening located within the interior area and configured to remove spent fluid and other debris from the interior area during use; and

EDGE.218WO -78- Knobbe, Martens, Olson & Bear, LLP at least one protrusion positioned within the interior area and extending distally to or near the distal end with a first protrusion height; wherein the peripheral lip has a peripheral lip durometer and the at least one protrusion has a protrusion durometer, the peripheral lip durometer being greater than the protrusion durometer; wherein the at least one protrusion creates a fluid flow pathway from the at least one fluid delivery opening(s) to the at least one waste opening(s) along the interior area during use; and wherein the spent fluid and other debris is removed from the tip via the at least one waste opening and the handpiece.

62. The tip of Claim 61, wherein the spent fluid and other debris received through the at least one waste opening accumulate in a waste collection region which is in fluid connection with the handpiece.

63. The tip of Claim 62, wherein the waste collection region is annular or substantially annular.

64. The tip of Claim 61 , wherein a height of the peripheral lip is larger than a height than any of the at least one protrusion.

65. The tip of Claim 61, wherein a height of the at least one protrusion varies.

66. The tip of Claim 61, wherein a height of the at least one protrusion increases as the protrusion approaches the peripheral lip.

67. The tip of Claim 61, wherein the peripheral lip durometer is lower than the durometer of at least one protrusion.

68. The tip of Claim 61, wherein a surface of at least one of the peripheral lip or the at least one protrusion which could contact skin additionally comprises an abrasive feature.

69. The tip of Claim 68, wherein the abrasive feature is selected from the group comprising: a ribbed surface, a pored surface, an abrasive material, an abrasive chemical composition, and a surface with sharp or abrasive features.

70. The tip of Claim 68, wherein the abrasive feature comprises a plurality of abrasive features.

71. The tip of Claim 61 , wherein a distal most surface of the at least one protrusion is not parallel with a plane defined by a distal most surface of the peripheral lip.

EDGE.218WO -79- Knobbe, Martens, Olson & Bear, LLP

72. The tip of Claim 61, wherein the tip further comprises an at least second protrusion.

73. The tip of Claim 72, wherein the at least second protrusion has a second protrusion height measured distally from the interior area.

74. The tip of Claim 73, wherein the second protrusion height is different than the first protrusion height.

75. The tip of Claim 73, wherein the second protrusion height is the same or substantially the same as the first protrusion height.

76. The tip of Claim 61, wherein the tip comprises one or more rigid or semi-rigid materials.

77. The tip of Claim 61, wherein the tip comprises at least one plastic material.

78. The tip of Claim 61, wherein the tip comprises at least one metal or alloy.

79. The tip of Claim 61, wherein the tip is disposable.

80. The tip of Claim 61, wherein the tip is reusable.

81. The tip of Claim 61 , wherein the tip is manufactured or otherwise produced as a unitary or monolithic item.

82. The tip of Claim 61, wherein a plane along a distal face of the distal portion of the tip is angled relative to a longitudinal axis of the tip and relative to an axis perpendicular to the longitudinal axis.

83. The tip of Claim 82, wherein an angle of the tip relative to the axis perpendicular to the longitudinal axis is 10 to 30 degrees.

84. The tip of Claim 61, wherein the tip is configured to be used on a torso of a subject.

85. The tip of Claim 61 , wherein the tip is configured to be used on a lip of a subject.

86. The tip of Claim 61, wherein the tip is configured to be used on a scalp of a subject.

87. The tip of Claim 61, wherein the tip comprises at least two separable pails configured to secure to one another along an interface point.

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88. The tip of Claim 61 , wherein the at least one protrusion is selected from the group comprising: a raised opening, a distally extended protrusion, a partitioned cell, a flow director or diverter, an internal wall or baffle, an internal bowl or other recess, a bar, a stem, and another protruding and/or recessed member or feature.

89. A tip configured to be secured to a distal end of a handpiece of a skin treatment system, the tip comprising: a distal portion configured to contact skin and a proximal portion configured to secure to a handpiece; a peripheral lip extending to the distal end, the peripheral lip defining an interior area; and at least one protrusion positioned within the interior area and extending distally to or near the distal end with a first protrusion height; wherein the at least one protrusion creates a fluid flow pathway from the at least one fluid delivery opening(s) to the at least one waste opening(s) along the interior area during use.

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