WO2024177171A1

WO2024177171A1 - Intevertebral body fusion prosthesis

Info

Publication number: WO2024177171A1
Application number: PCT/KR2023/002520
Authority: WO
Inventors: 정의수; 조사무엘; 박준석
Original assignee: (주)시지바이오; 이노팀 주식회사
Priority date: 2023-02-22
Filing date: 2023-02-22
Publication date: 2024-08-29

Abstract

An intervertebral body fusion prosthesis according to an embodiment of the present invention comprises: a plate; a driving member to which the plate is movably connected; a guide member disposed between the plate and the driving member; and a fastening member which is coupled to the guide member and the driving member and which, when driven, relatively moves forward or backward with respect to the guide member together with the driving member, wherein, when the fastening member is driven, the plate is displaced as the guide member moves forward with respect to the fastening member and the driving member, the frontward portion of the plate is moved in a direction away from the bottom surface of the driving member to increase an angle formed by the plate with the guide member, and after the angle increases by a set angle, the entire plate moves in a direction away from the bottom surface of the driving member and the height thereof increases.

Description

Intervertebral fusion prosthesis

The present invention relates to an intervertebral fusion prosthesis, and more particularly, to an intervertebral fusion prosthesis that can be used in fusion surgery, which is a surgical treatment method for spinal diseases.

Intervertebral fusion prosthesis is a device used in fusion, a surgical treatment method for spinal diseases. When a disc is ruptured or weakened due to disease or accident, it compresses the spinal nerves and causes pain. In this case, the damaged disc is removed, and an intervertebral fusion prosthesis is inserted into the intervertebral body where the damaged part was removed to restore and maintain the space and curvature (lordosis) between the vertebrae, thereby performing fusion between the vertebrae.

Intervertebral fusion implants are inserted between vertebrae where degenerative discs have been removed, and they support the vertebral bodies until the spine is fused. In addition, intervertebral fusion implants secure the space between the vertebrae, thereby relieving pain and restoring the stability of the spine.

In general, intervertebral fusion implants are individually manufactured according to the lordosis and height of the spine. However, when performing surgery through the posterior entry method, it is often difficult to use an intervertebral fusion implant with the lordosis and height required by the patient. This is because most patients requiring fusion surgery have degenerative changes in the spine, making it difficult to secure a wide space for implanting an intervertebral fusion implant.

In this situation, expandable intervertebral fusion prostheses that are easy to insert into the disc space at the time of implantation due to their low height and can expand the lordosis or height after being positioned at the desired point are being introduced. However, most of the expandable intervertebral fusion prostheses that have been introduced so far have a form that can expand either the lordosis or the height, and a technology that can expand both the lordosis and the height has not yet been developed. Accordingly, the need for the development of an intervertebral fusion prosthesis that can control both the lordosis and the height while operating stably is increasing.

(Patent Document 1) Korean Patent Publication No. 10-2021-0037997

(Patent Document 2) Korean Patent Publication No. 10-1371418

The present invention is intended to solve the problems of the above-mentioned prior art,

An object of the present invention is to provide an intervertebral body fusion prosthesis having a structure capable of adjusting both the lordotic angle and the height between the vertebral bodies.

Another object of the present invention is to provide an intervertebral body fusion prosthesis capable of effectively and stably sequentially increasing the angle of lordosis and increasing the height.

According to one aspect of the present invention, there is provided an intervertebral body fusion prosthesis comprising: a plate; a driving member to which the plate is movably connected; a guide member disposed between the plate and the driving member; and a fastening member coupled to the guide member and the driving member and configured to move forward or backward relative to the guide member as one body with the driving member when driven, wherein when the fastening member is driven, the guide member moves forward with respect to the fastening member and the driving member, thereby displacing the plate, wherein a front portion of the plate moves away from a lower surface of the driving member so that an angle formed by the plate with the guide member increases, and after the angle increases by a set angle, the entire plate moves away from a lower surface of the driving member so as to increase in height.

At this time, the guide member may have a front guide part formed to be inclined at the front portion and a rear guide part formed to be inclined at the rear portion, and the plate may have a front guided part and a rear guided part formed to be inclined so as to be guided by the front guide part and the rear guide part, respectively, when displaced.

Additionally, when the plate is displaced, the angle may increase until the inclination of the front guide portion and the inclination of the front guide portion are matched.

In addition, the slope of the rear guide part and the slope of the rear guide part can be matched while the slope of the front guide part and the slope of the front guide part are matched.

In addition, the guide member may have a guide body formed by penetrating upward and downward, the driving member may be disposed inside the guide body, and may have a coupling portion to which the plate is connected and the fastening member is coupled, and an opposing plate portion connected to the coupling portion so as to face the plate with the guide member interposed therebetween.

In addition, the guide member may further have a screw hole formed at the front, and the fastening member may have a screw body part that is screw-connected to the screw hole.

In addition, the fastening member may further include a head portion connected to the rear end of the screw body portion, and the coupling portion may include a screw coupling hole formed so that the head portion can be rotatably coupled.

In addition, the guide member may further have a rear hole formed through the rear to communicate with the guide body, and the coupling portion may further have a guide hole formed through the rear hole to allow a driving tool passing through the rear hole to enter the head portion.

Additionally, the plate may have a first connecting portion formed in a vertical direction, and the joining portion may have a second connecting portion movably connected to the first connecting portion in a vertical direction.

In addition, the guide member may further have lateral guide portions formed in the front-back direction on both side walls of the guide body, and the coupling portion may have a lateral guided portion guided by the lateral guide portion when moving relative to the guide member.

In addition, the lateral guide portion is provided at the upper end of both side walls of the guide body, and the lateral guide portion is provided in a pin shape and is positioned to penetrate the coupling portion left and right, and one end and the other end can be respectively secured to the lateral guide portion.

According to an embodiment of the present invention, the lordosis angle and height of the spine can both be adjusted through a plate that forms a predetermined angle by vertically rising the front portion according to the rotation of the screw and then moves vertically overall to increase in height, thereby ensuring an appropriate lordosis angle and height of the spine for each patient when performing a fusion surgery.

According to an embodiment of the present invention, sequential progression of anterior angle increase and height increase can be efficiently and stably achieved through displacement of the plate through the front guide portion and rear guide portion of the body and the front guide portion and rear guide portion of the plate, thereby allowing fusion surgery to be easily performed.

FIG. 1 is a perspective view of an intervertebral body fusion prosthesis according to one embodiment of the present invention.

FIG. 2 is a perspective view showing an intervertebral body fusion prosthesis according to one embodiment of the present invention from another direction.

Figure 3 is an exploded perspective view of an intervertebral body fusion prosthesis according to one embodiment of the present invention.

FIG. 4 is a perspective view of a plate of an intervertebral body fusion prosthesis according to one embodiment of the present invention with the angle expanded.

FIG. 5 is a side view of a plate of an intervertebral body fusion prosthesis according to one embodiment of the present invention with the angle expanded.

FIG. 6 is a cross-sectional side view showing a state in which the angles of the anterior guide portion and the anterior guide portion of an intervertebral body fusion prosthesis according to one embodiment of the present invention are aligned.

FIG. 7 is a perspective view showing an increased height after the plate of an intervertebral body fusion prosthesis is angle-expanded according to one embodiment of the present invention.

FIG. 8 is a side view showing a state in which the height of the plate of an intervertebral body fusion prosthesis according to one embodiment of the present invention has increased after the angle has been expanded.

FIG. 9 is a drawing showing a process in which an intervertebral body fusion prosthesis according to one embodiment of the present invention is used in PLIF.

FIG. 10 is a drawing showing a process in which an intervertebral body fusion prosthesis according to one embodiment of the present invention is used in TLIF.

FIGS. 11 to 13 are drawings each illustrating a part of a modified example of an intervertebral body fusion prosthesis according to one embodiment of the present invention.

The words and terms used in this specification and claims should not be construed as limited to their usual or dictionary meanings, but should be interpreted as having meanings and concepts consistent with the technical idea of the present invention, in accordance with the principles by which the inventor can define terms and concepts in order to best describe his or her invention.

The embodiments described in this specification and the configurations illustrated in the drawings correspond to preferred embodiments of the present invention and do not represent all of the technical ideas of the present invention, so the configurations may have various equivalents and modified examples that can replace them at the time of filing of the present invention.

In this specification, it should be understood that terms such as “include” or “have” are intended to describe the presence of a feature, number, step, operation, component, part or combination thereof described in the specification, but do not exclude in advance the possibility of the presence or addition of one or more other features, numbers, steps, operations, components, parts or combinations thereof.

When a component is said to be "in front of," "behind," "on the side," "above," or "below" another component, unless there are special circumstances, it includes not only being positioned "in front," "behind," "on the side," "above," or "below" the other component in direct contact with it, but also cases where there are other components intervening therebetween. Furthermore, when a component is said to be "connected" to another component, unless there are special circumstances, it includes not only being directly connected to one another, but also indirectly connected to one another.

Hereinafter, an intervertebral body fusion prosthesis according to one embodiment of the present invention will be described with reference to the drawings.

FIG. 1 is a perspective view of an intervertebral fusion prosthesis according to one embodiment of the present invention, and FIG. 2 is a perspective view showing an intervertebral fusion prosthesis according to one embodiment of the present invention from another direction. In addition, FIG. 3 is an exploded perspective view of an intervertebral fusion prosthesis according to one embodiment of the present invention.

The intervertebral body fusion prosthesis (1) according to one embodiment of the present invention is a device used in fusion, which is a surgical treatment method for spinal diseases. The intervertebral body fusion prosthesis (1) is inserted between vertebrae from which degenerative discs have been removed, and supports the intervertebral bodies until the fusion of the vertebrae. The intervertebral body fusion prosthesis (1) according to one embodiment of the present invention enables securing both the lordosis and height of the spine.

Referring to FIGS. 1 to 3, an intervertebral body fusion prosthesis (1) according to one embodiment of the present invention may include a plate (100), a driving member (200), a guide member (300), and a fastening member (400).

The plate (100) forms the anterior angle and height of the intervertebral body fusion prosthesis (1). In one embodiment of the present invention, the plate (100) forms the upper surface of the intervertebral body fusion prosthesis (1). The plate (100) may include a plate body (110), an anterior guide member (120), a posterior guide member (130), and a first connecting member (140).

The plate body (110) has an overall square shape and is penetrated in the vertical direction. The plate body (110) has side walls on all sides based on the penetrated portion.

The front guide member (120) is guided by the front guide member (320) of the guide member (300) described below. When the plate (100) moves relative to the guide member (300) and the front guide member (120) is guided by the front guide member (320), the front portion of the plate (100) can be raised. In one embodiment of the present invention, the front guide member (120) is formed by being recessed into the inner surface of both sides of the plate body (110), and is formed by being recessed in a downwardly inclined form from the rear to the front.

The rear guide member (130) is guided by the rear guide member (330) of the guide member (300) described below. When the plate (100) moves relative to the guide member (300) and the rear guide member (130) is guided by the rear guide member (330), the rear portion of the plate (100) can be raised. In one embodiment of the present invention, the rear guide member (130) is provided on the rear side wall of the plate body (110) and is formed to be inclined downward from the rear to the front.

The first connecting portion (140) connects the plate (100) to the driving member (200). In one embodiment of the present invention, the first connecting portion (140) can be movably connected in the vertical direction to the second connecting portion (212) of the driving member (200) described below. In one embodiment of the present invention, the first connecting portion (140) can have a pillar shape that protrudes from the inner surface of both sides of the plate body (110) and extends in the vertical direction.

The driving member (200) is configured to be movably connected to the plate (100). The fastening member (400) is movably connected to the driving member (200), and the driving member (200) moves relative to the guide member (300) as a unit with the fastening member (400) according to the driving of the fastening member (400). In one embodiment of the present invention, the driving member (200) may include a coupling portion (210) and an opposing plate portion (220).

The coupling part (210) is arranged in the guide body (310) of the guide member (300), is connected to the plate (100), and is connected to the fastening member (400). The coupling part (210) may include a box-shaped coupling part body (211) that penetrates upward and downward, a second coupling part (212) provided on both sides of the coupling part body (211) so that the first coupling part (140) of the plate (100) can be movably connected in the upward and downward direction, a screw coupling hole (213) formed in the forward and backward direction through the front side wall of the coupling part body (211) so that the fastening part (400) can be rotatably connected, and a guide hole (214) formed in the forward and backward direction through the rear side wall of the coupling part body (211) so that a driving tool for rotating a screw connected to the screw coupling hole (213) can reach the screw coupling hole (213).

The opposing plate part (220) is connected to the connecting part (210) so as to face the plate (100) with the guide member (300) interposed therebetween. More specifically, the opposing plate part (220) can be connected to the lower part of the connecting part (210) with a predetermined area. That is, the opposing plate part (220) can form the lower surface of the intervertebral body fusion prosthesis (1). The opposing plate part (220) can have a shape that is perforated from top to bottom so as to be in communication with the perforated portion of the connecting part body (211).

The guide member (300) is arranged between the plate (100) and the driving member (200). The guide member (300) guides the displacement of the plate (100) while moving forward or backward relative to the driving member (200) and the fastening member (400). In one embodiment of the present invention, the guide member (300) may include a guide body (310), a front guide portion (320), a rear guide portion (330), a screw hole (340), and a rear hole (350).

The guide body (310) has a frame shape with the upper and lower parts penetrating. The guide body (310) may have an overall square shape. The coupling part (210) of the driving member (200) is arranged inside the guide body (310), and the driving member (200) moves relative to the guide member (300) within the guide body (310) according to the rotation of the fastening member (400) rotatably coupled to the coupling part (210).

The front guide part (320) is formed to be inclined at the front portion of the guide body (310). The front guide part (320) guides the front guided part (120) of the plate (100) during relative movement with the plate (100) and guides the rise of the front portion of the plate (100). In one embodiment of the present invention, the front guide part (320) is formed to protrude from the side walls of the front portion of the guide body (310) to both sides and to be inclined downward from the rear to the front at a predetermined angle.

As shown in FIGS. 1 to 3, in the non-extended state of the plate (100), the angle formed by the front guide portion (320) with respect to the ground is formed smaller than the angle formed by the front guided portion (120) of the plate (100) with respect to the ground. Accordingly, when the plate (100) is displaced, the front portion of the plate (100) rises until the angles formed by the front guide portion (320) and the front guided portion (120) with respect to the ground become the same, and an expansion of the lordosis angle may occur.

The rear guide part (330) is formed to be inclined at the rear portion of the guide body (310). The rear guide part (330) guides the rear guided part (130) of the plate (100) during relative movement with the plate (100). In other words, the rise of the rear portion of the plate (100) is guided by the rear guide part (330). In one embodiment of the present invention, the rear guide part (330) is formed to protrude from the side walls of the rear portion of the guide body (310) to both sides and to be inclined downward from the rear to the front at a predetermined angle.

The angle formed by the rear guide part (330) with respect to the ground may be formed to be the same as the angle formed by the front guide part (320) with respect to the ground. Meanwhile, the angle formed by the rear guide part (330) with respect to the ground is formed to be smaller than the angle formed by the rear guide part (130) with respect to the ground when the plate (100) is in a non-extended state. Accordingly, when the plate (100) is displaced, the front part of the plate (100) rises until the rear guide part (130) of the plate (100) and the rear guide part (320) come into contact, and an expansion of the lordosis angle may occur. In a state where the inclination of the front guide part (320) and the inclination of the front guide part (120) are matched, the inclination of the rear guide part (330) and the inclination of the rear guide part (130) may be matched.

The screw hole (340) may be formed in the front of the guide body (310). The screw hole (340) may be formed by penetrating the front side wall of the guide body (310) in the front and rear directions. When the fastening member (400) is provided as a screw, the fastening member (400) that is screw-coupled to the engaging portion (210) of the driving member (200) arranged in the guide body (310) may be arranged to engage with the screw hole (340). Accordingly, when the fastening member (400) is driven, the guide member (300) can move relative to the driving member (200) and the fastening member (400) in the forward or backward direction.

The rear hole (350) is formed at the rear of the guide body (310) and communicates with the guide body (310). More specifically, the rear hole (350) may be formed by penetrating the rear side wall of the guide body (310) in the front-back direction. The rear hole (350) allows a driving tool for driving the fastening member (400) to enter the interior of the guide body (310). The driving tool that enters the guide body (310) through the rear hole (350) can pass through the guide hole (214) of the coupling portion (210) and reach the screw coupling hole (213) side to rotate the fastening member (400) coupled to the screw coupling hole (213).

The fastening member (400) provides a driving force for the displacement of the plate (100). In one embodiment of the present invention, the fastening member (400) may be provided as a screw. At this time, the fastening member (400) may be engaged with the guide member (300) while being rotatably coupled to the driving member (200). When the fastening member (400) rotates, the guide member (300) moves relative to the driving member (200) and moves forward or backward, and the displacement of the plate (100) occurs according to the relative movement of the guide member (300). Since the plate (100) and the driving member (200) are fixed in a state where the intervertebral body fusion prosthesis (1) is inserted into the space between the vertebrae of the patient, the guide member (300) moves forward or backward when the fastening member (400) rotates.

In one embodiment of the present invention, the fastening member (400) may include a head portion (410) that is rotatably coupled to a screw coupling hole (213) of a coupling portion (210) of a driving member (200) and a screw body portion (420) that extends forward from the head portion (410) and is screw-coupled to a screw hole (340) of a guide member (300).

Below, the operation of the intervertebral body fusion prosthesis (1) according to one embodiment of the present invention will be examined.

When the fastening member (400) rotates in one direction while the plate (100) is not extended relative to the guide member (300), the guide member (300) moves forward relative to the fastening member (400) and the driving member (200), causing the plate (100) to be displaced. At this time, the front portion of the plate (100) is preferentially moved in the vertical direction, thereby increasing the angle that the plate (100) forms with the guide member (300).

FIG. 4 is a perspective view showing an expanded angle of a plate of an intervertebral fusion prosthesis according to one embodiment of the present invention. In addition, FIG. 5 is a side view showing an expanded angle of a plate of an intervertebral fusion prosthesis according to one embodiment of the present invention, and FIG. 6 is a cross-sectional side view showing an identical angle of an anterior guide portion and an anterior guided portion of an intervertebral fusion prosthesis according to one embodiment of the present invention.

Referring to FIGS. 4 to 6, the angular expansion of the front portion of the plate (100) is performed until the angle (α) formed by the front guide member (120) of the plate (100) with respect to the ground and the angle (β) formed by the front guide member (320) of the guide member (300) with respect to the ground become equal. The angle (β) formed by the front guide member (320) with respect to the ground may correspond to the lordosis of the spine that the intervertebral body fusion prosthesis (1) can provide. In addition, as the front portion of the plate (100) rises, the plate (100) moves rearward relative to the guide member (300), causing the rear guide member (130) of the plate (100) to come into contact with the rear guide member (320).

In this way, at the initial stage of displacement of the plate (100), the front part of the plate (100) rises until the angle formed by the front guide part (320) and the front guide part (120) with respect to the ground becomes the same. As a result, an expansion of the lordosis angle may occur. Through this process, the intervertebral body fusion prosthesis (1) can make the lordosis angle of the spine a preset angle while being inserted into the intervertebral body space of the patient.

FIG. 7 is a perspective view of a state in which the height of a plate of an intervertebral fusion prosthesis has increased after angular expansion according to one embodiment of the present invention. In addition, FIG. 8 is a side view of a state in which the height of a plate of an intervertebral fusion prosthesis has increased after angular expansion according to one embodiment of the present invention.

Referring to FIGS. 7 and 8, when the front portion of the plate (100) is raised to the maximum, the angle formed by the front guide member (120) of the plate (100) with respect to the ground and the angle formed by the front guide member (320) of the guide member (300) with respect to the ground become the same, and when the rear guide member (130) of the plate (100) and the rear guide member (320) are in contact, if the fastening member (400) is additionally rotated in one direction, the entire plate (100) moves in the vertical direction and the height increases. That is, after the angle increases by the set angle, when the fastening member (400) is further rotated, the front guide member (120) and the rear guide member (130) of the plate (100) are in contact with the front guide member (320) and the rear guide member (330) of the guide member (300), respectively, and the guide member (300) moves forward relative to the driving member (200), and the plate (100) moves vertically upward as a whole, thereby expanding the height of the intervertebral body fusion prosthesis (1). At this time, the expanded height can be set corresponding to the height of the intervertebral space that the intervertebral body fusion prosthesis (1) intends to secure.

Meanwhile, with respect to the relative movement between the driving member (200) and the guide member (300), the guide member (300) may further include a lateral guide portion (360) formed in the front-back direction on both side walls of the guide body (310), and the coupling portion (210) of the driving member (200) may include a lateral guide portion (215) guided by the lateral guide portion (360) when moving relative to the guide member (300). In one embodiment of the present invention, the lateral guide portion (360) is provided as a corner of the upper end of both side walls of the guide body (310), and the lateral guide portion (215) is provided in a pin shape and is arranged to penetrate the coupling portion (210) left and right, and one end and the other end are respectively seated on the lateral guide portion (360). In this regard, the joint part (210) of the driving member (200) may further have a lateral guide part arrangement hole (215a) formed to penetrate left and right so that the lateral guide part (215) may be arranged through it.

FIG. 9 is a drawing showing a process in which an intervertebral fusion prosthesis according to one embodiment of the present invention is used in PLIF. FIG. 10 is a drawing showing a process in which an intervertebral fusion prosthesis according to one embodiment of the present invention is used in TLIF.

Referring to FIGS. 9 and 10, an intervertebral fusion prosthesis (1) according to one embodiment of the present invention can be used for both PLIF (Posterior Lumbar Interbody Fusion) and TLIF (Transforaminal Lumbar Interbody Fusion). The intervertebral fusion prosthesis (1) is inserted into the space between the upper vertebral body (A1) and the lower vertebral body (A2) to enable expansion of both lordosis and height. In addition, it enables minimally invasive surgery upon insertion by expanding after insertion into the patient's body.

Referring to FIGS. 11 to 13, a modified example of an embodiment of the present invention is such that, compared to the embodiment of the present invention, the front guide portion (320a) of the guide member (300) is not formed in a form that protrudes to both sides from the side walls of the front portion of the guide body (310), but is provided on the side walls of the front portion of the guide body (310). That is, the side walls of the front portion of the guide body (310) are formed as the front guide portion (320a) at a predetermined angle so as to be inclined downward from the rear to the front. In addition, correspondingly, the front guide portion (120a) of the plate (100) is provided on the inner surface of the front side wall of the plate body (110) in a form that is inclined downward from the rear to the front. Through this modification, the structure of the front guide portion (320a) and the front guide portion (120a) can be more easily implemented while maintaining the function of the intervertebral body fusion prosthesis (1) according to the embodiment of the present invention described above.

Although one embodiment of the present invention has been described above, the spirit of the present invention is not limited to the embodiment presented in this specification, and those skilled in the art who understand the spirit of the present invention will be able to easily propose other embodiments by adding, changing, deleting, or adding components within the scope of the same spirit, but this will also be considered to fall within the spirit of the present invention.

Claims

plate;

A driving member to which the above plates are movably connected;

A guide member arranged between the above plate and the driving member; and

A fastening member coupled to the above guide member and the above driving member and configured to move forward or backward relative to the guide member as one unit with the driving member when driven;

An intervertebral body fusion prosthesis in which, when the fastening member is driven, the guide member moves forward with respect to the fastening member and the driving member, the plate is displaced, and the front portion of the plate moves in a direction away from the bottom surface of the driving member so that the angle formed by the plate with the guide member increases, and after the angle increases by a set angle, the entire plate moves in a direction away from the bottom surface of the driving member so that the height increases.
In the first paragraph,

The above guide member has a front guide part formed to be inclined at the front portion and a rear guide part formed to be inclined at the rear portion.

An intervertebral body fusion prosthesis having an anterior guide portion and a posterior guide portion formed to be inclined so as to be guided by the anterior guide portion and the posterior guide portion, respectively, when the plate is displaced.
In the second paragraph,

An intervertebral body fusion prosthesis in which the angle increases until the inclination of the anterior guide portion and the inclination of the anterior guide portion are identical when the plate is displaced.
In the third paragraph,

An intervertebral body fusion prosthesis in which the inclination of the anterior guide part and the inclination of the anterior guide part are identical, and the inclination of the posterior guide part and the inclination of the posterior guide part are identical.
In the first paragraph,

The above guide member has a guide body formed by penetrating upward and downward,

An intervertebral body fusion prosthesis, wherein the driving member is positioned inside the guide body and has a connecting portion to which the plate is connected and the fastening member is connected, and an opposing plate portion connected to the connecting portion so as to face the plate with the guide member interposed therebetween.
In paragraph 5,

The above guide member further has a screw hole formed in the front,

The above fastening member is an intervertebral body fusion prosthesis having a screw body that is screw-connected to the screw hole.
In paragraph 6,

The above fastening member further has a head portion connected to the rear end of the screw body portion,

An intervertebral body fusion prosthesis having a screw joint hole formed so that the head portion can be rotatably joined to the above-mentioned joint portion.
In paragraph 7,

The above guide member further has a rear hole formed through the rear to communicate with the guide body,

An intervertebral body fusion prosthesis in which the above-mentioned joint part further has a guide hole formed through the above-mentioned rear hole so that a driving tool passing through the above-mentioned rear hole can enter the above-mentioned head part.
In paragraph 5,

The above plate has a first connecting portion formed in the vertical direction,

An intervertebral body fusion prosthesis, wherein the above-mentioned connecting portion has a second connecting portion that is movably connected in the upper and lower direction to the above-mentioned first connecting portion.
In paragraph 5,

The above guide member further has a lateral guide portion formed in the front-back direction on both side walls of the guide body,

An intervertebral body fusion prosthesis having a lateral guide member that is guided by the lateral guide member when the above-mentioned connecting member moves relative to the above-mentioned guide member.
In Article 10,

An intervertebral body fusion prosthesis in which the above-mentioned lateral guide portion is provided at the upper end of both side walls of the guide body, and the above-mentioned lateral guide portion is provided in a pin shape and is positioned to penetrate the connecting portion left and right, and one end and the other end are respectively secured to the above-mentioned lateral guide portion.