WO2024071406A1 - Water-in-oil emulsion composition - Google Patents

Abstract

[Problem] To provide a water-in-oil emulsion composition and a water repellent agent, each of which exhibits excellent water repellency and excellent storage stability, while having less stickiness even if vaseline is contained therein. [Solution] A water-in-oil emulsion composition which contains, based on the total mass of the water-in-oil emulsion composition, 2.0% by mass to 30.0% by mass of vaseline, a silicone-based film-forming agent, a polyglycerol fatty acid ester and an ester oil.　A water repellent agent which contains, based on the total mass of the water repellent agent, 2.0% by mass to 30.0% by mass of vaseline, a silicone-based film-forming agent, a polyglycerol fatty acid ester and an ester oil.

Description

Water-in-oil emulsion composition

The present invention relates to a water-in-oil emulsion composition and a water repellent.

As the aging of society progresses, the number of elderly people who are bedridden and require nursing care is increasing year by year, and so-called diaper rash, a condition that causes redness and eczema on the skin of the buttocks and genitals where the diaper is in contact with the skin, is becoming a problem.
Means for preventing or treating diaper rash include skin care methods using preparations, and examples of such preparations include petrolatum preparations such as petrolatum and creams containing petrolatum as a main component, and non-petrolatum preparations such as a composition for application to mammalian skin (Patent Document 1) comprising an emulsion comprising (a) an acrylate polymer in an amount of about 0.25% to about 10% by weight, and (b) a silicone resin in an amount of about 0.5% to about 15% by weight, wherein (a) and (b) comprise an oil phase dissolved in a non-volatile emollient oil.

JP 2017-519773 A

Vaseline preparations have excellent water repellency and moisturizing properties, but are sticky and have a poor feel when used. On the other hand, non-vaseline preparations have a good feel when used, but have problems with insufficient water repellency and moisturizing properties.

The object of the present invention is to provide a water-in-oil emulsion composition and water repellent that contain petrolatum but are less sticky and have excellent water repellency and storage stability.

The inventors conducted extensive research to solve the above problems, and discovered that by using a combination of a silicone film-forming agent, a polyglycerol fatty acid ester, and an ester oil in a composition containing petrolatum, the composition has one or more of the following properties: low stickiness despite containing petrolatum, water repellency equivalent to that of petrolatum, excellent storage stability, excellent moisture retention, and tape can be applied to skin to which the composition of the present invention has been applied, and thus completed the present invention.

That is, the present invention provides
[1]
2.0% to 30.0% by mass of petrolatum based on the total mass of the water-in-oil emulsion composition;
Silicone film-forming agents,
A water-in-oil emulsion composition comprising a polyglycerol fatty acid ester and an ester oil;
[2]
The water-in-oil emulsion composition according to [1], wherein the silicone-based film-forming agent is one or more silicone-based film-forming agents selected from the group consisting of trimethylsiloxysilicate, polypropylsilsesquioxane, (acrylates/dimethicone) copolymer, (norbornene/tris(trimethylsiloxy)silylnorbornene) copolymer, tri(trimethylsiloxy)silylpropylcarbamic acid pullulan, (acrylates/polytrimethylsiloxy methacrylate) copolymer, and (trimethylsiloxysilicate/dimethiconol) crosspolymer;
[3]
The water-in-oil emulsion composition according to [1], wherein the polyglycerol fatty acid ester is one or more polyglycerol fatty acid esters selected from the group consisting of polyglyceryl-2 isostearate, polyglyceryl-2 oleate, polyglyceryl-6 polyricinoleate, polyglyceryl-10 polyricinoleate, polyglyceryl-10 pentahydroxystearate, polyglyceryl-10 pentaisostearate, polyglyceryl-6 pentaoleate, and polyglyceryl-10 pentaoleate;
[4]
The water-in-oil emulsion composition according to [1], wherein the ester oil is one or more ester oils selected from the group consisting of triethylhexanoin, ethylhexyl palmitate, octyldodecyl myristate, di(octyldodecyl/phytosteryl/behenyl) lauroyl glutamate, jojoba seed oil, and tri(caprylic/capric acid)glyceryl;
[5]
the silicone-based film-forming agent is one or more silicone-based film-forming agents selected from the group consisting of trimethylsiloxysilicate and polypropylsilsesquioxane;
The polyglycerol fatty acid ester is one or more polyglycerol fatty acid esters selected from the group consisting of polyglyceryl-2 isostearate and polyglyceryl-6 polyricinoleate,
The ester oil is one or more ester oils selected from the group consisting of triethylhexanoin, ethylhexyl palmitate, di(octyldodecyl/phytosteryl/behenyl) lauroyl glutamate, and jojoba seed oil.
The water-in-oil emulsion composition according to [1],
[6]
The water-in-oil emulsion composition according to [1], wherein the formulation of the water-in-oil emulsion composition is a cream.

The present invention also provides a method for producing a method for manufacturing a semiconductor device comprising the steps of:
[7]
2.0% to 30.0% by weight of petrolatum, based on the total weight of the water repellent;
Silicone film-forming agents,
A water repellent agent comprising a polyglycerol fatty acid ester and an ester oil;
[8]
The water repellent according to [7], wherein the silicone-based film-forming agent is one or more silicone-based film-forming agents selected from the group consisting of trimethylsiloxysilicate, polypropylsilsesquioxane, (acrylates/dimethicone) copolymer, (norbornene/tris(trimethylsiloxy)silylnorbornene) copolymer, tri(trimethylsiloxy)silylpropylcarbamic acid pullulan, (acrylates/polytrimethylsiloxy methacrylate) copolymer, and (trimethylsiloxysilicate/dimethiconol) crosspolymer.
[9]
The water repellent according to [7], wherein the polyglycerol fatty acid ester is one or more polyglycerol fatty acid esters selected from the group consisting of polyglyceryl-2 isostearate, polyglyceryl-2 oleate, polyglyceryl-6 polyricinoleate, polyglyceryl-10 polyricinoleate, polyglyceryl-10 pentahydroxystearate, polyglyceryl-10 pentaisostearate, polyglyceryl-6 pentaoleate, and polyglyceryl-10 pentaoleate.
[10]
The water repellent according to [7], wherein the ester oil is one or more ester oils selected from the group consisting of triethylhexanoin, ethylhexyl palmitate, octyldodecyl myristate, di(octyldodecyl/phytosteryl/behenyl) lauroyl glutamate, jojoba seed oil, and tri(caprylic/capric)glyceryl.
[11]
the silicone-based film-forming agent is one or more silicone-based film-forming agents selected from the group consisting of trimethylsiloxysilicate and polypropylsilsesquioxane;
The polyglycerol fatty acid ester is one or more polyglycerol fatty acid esters selected from the group consisting of polyglyceryl-2 isostearate and polyglyceryl-6 polyricinoleate,
The ester oil is one or more ester oils selected from the group consisting of triethylhexanoin, ethylhexyl palmitate, di(octyldodecyl/phytosteryl/behenyl) lauroyl glutamate, and jojoba seed oil.
The water repellent according to [7].
The present invention also provides a method for producing a method for manufacturing a semiconductor device comprising the steps of:
[12]
The water-in-oil emulsion composition according to [1], which is for skin protection;
[13]
The present invention relates to a water-in-oil emulsion composition according to [1], which is used as a nursing care product.

The present invention provides a water-in-oil emulsion composition that has one or more of the following characteristics: low stickiness despite containing petrolatum, water repellency equivalent to that of petrolatum, excellent storage stability, excellent moisture retention, and the ability to apply tape to skin to which the composition of the present invention has been applied.

The present invention provides a water repellent that has one or more of the following characteristics: low stickiness despite containing petrolatum, water repellency equivalent to that of petrolatum, excellent storage stability, excellent moisture retention, and the ability to apply tape to skin to which the water repellent of the present invention has been applied.

FIG. 1 is a graph showing the results of absorbance measurements in Test Example 5. FIG. 2 is a photograph of the artificial skin (artificial skin washed with water) after 8 hours in Test Example 5. FIG. 3 shows the results of home use test (1) in Test Example 6. FIG. 4 shows the results of the home use test (2) of Test Example 7.

[Water-in-oil emulsion composition]
The present invention relates to
2.0% to 30.0% by mass of petrolatum based on the total mass of the water-in-oil emulsion composition;
Silicone film-forming agents,
The present invention relates to a water-in-oil emulsion composition containing a polyglycerol fatty acid ester and an ester oil.

<Vaseline>
In the present invention, vaseline is a component that exhibits water repellency and moisturizing properties.
The petrolatum is not particularly limited, and examples thereof include white petrolatum and yellow petrolatum listed in the Japanese Pharmacopoeia, with white petrolatum being preferred.
The content of Vaseline is 2.0% to 30.0% by mass, preferably 3.0% to 20.0% by mass, and more preferably 5.0% to 15.0% by mass, based on the total mass of the water-in-oil emulsion composition. If the content of Vaseline is less than 2.0% by mass, the water-repellent and moisturizing effects may not be fully exhibited, and if it exceeds 30.0% by mass, the water-in-oil emulsion composition may become sticky, impairing the feeling of use, and the storage stability of the water-in-oil emulsion composition may not be fully obtained.

<Silicone-based film-forming agent>
In the present invention, the silicone-based film-forming agent is a component that reduces the stickiness of the petrolatum and exhibits storage stability when used in combination with the polyglycerol fatty acid ester and ester oil. In addition, the silicone-based film-forming agent can exert a film-forming effect depending on its content.
The silicone-based film-forming agent is not particularly limited, and is preferably one or more silicone-based film-forming agents selected from the group consisting of trimethylsiloxysilicate, polypropylsilsesquioxane, (acrylates/dimethicone) copolymer, (norbornene/tris(trimethylsiloxy)silylnorbornene) copolymer, tri(trimethylsiloxy)silylpropylcarbamic acid pullulan, (acrylates/polytrimethylsiloxy methacrylate) copolymer, and (trimethylsiloxysilicate/dimethiconol) crosspolymer, and more preferably one or more silicone-based film-forming agents selected from the group consisting of trimethylsiloxysilicate and polypropylsilsesquioxane.

The content of the silicone-based film-forming agent is not particularly limited as long as it is an amount sufficient to reduce the stickiness of the petrolatum and enable stable storage of the water-in-oil emulsion composition when used in combination with the polyglycerol fatty acid ester and ester oil, and is preferably 0.5% to 10.0% by mass, and more preferably 1.0% to 6.0% by mass, based on the total mass of the water-in-oil emulsion composition. If the content of the silicone-based film-forming agent is less than 0.5% by mass, the stickiness of the petrolatum may not be sufficiently reduced, and if it exceeds 10.0% by mass, the storage stability of the water-in-oil emulsion composition may not be sufficient.

<Polyglycerol fatty acid ester>
In the present invention, polyglycerol fatty acid ester is a component that reduces the stickiness of petrolatum and exhibits storage stability when used in combination with a silicone-based film-forming agent and an ester oil. In addition, polyglycerol fatty acid ester can exert an emulsifying effect depending on its content.
The polyglycerol fatty acid ester is not particularly limited, and is preferably one or more polyglycerol fatty acid esters selected from the group consisting of polyglyceryl-2 isostearate, polyglyceryl-2 oleate, polyglyceryl-6 polyricinoleate, polyglyceryl-10 polyricinoleate, polyglyceryl-10 pentahydroxystearate, polyglyceryl-10 pentaisostearate, polyglyceryl-6 pentaoleate, and polyglyceryl-10 pentaoleate, and more preferably one or more polyglycerol fatty acid esters selected from the group consisting of polyglyceryl-2 isostearate and polyglyceryl-6 polyricinoleate.

The content of the polyglycerol fatty acid ester is not particularly limited as long as it is an amount sufficient to reduce the stickiness of the petrolatum and enable stable storage of the water-in-oil emulsion composition when used in combination with a silicone-based film-forming agent and an ester oil, and is preferably 1.0% to 7.0% by mass, and more preferably 1.5% to 5.5% by mass, based on the total mass of the water-in-oil emulsion composition. If the content of the polyglycerol fatty acid ester is less than 1.0% by mass, the stickiness of the petrolatum may not be sufficiently reduced, and if it exceeds 7.0% by mass, the storage stability of the water-in-oil emulsion composition may not be sufficient.

<Ester oil>
In the present invention, the ester oil is a component that reduces the stickiness of the petrolatum and exhibits storage stability when used in combination with a silicone-based film-forming agent and a polyglycerin fatty acid ester. Furthermore, depending on the content, the ester oil can exhibit an emollient effect.
The ester oil is not particularly limited, and is preferably one or more ester oils selected from the group consisting of triethylhexanoin, ethylhexyl palmitate, octyldodecyl myristate, di(octyldodecyl/phytosteryl/behenyl) lauroyl glutamate, jojoba seed oil, and tri(caprylic acid/capric acid)glyceryl, and more preferably one or more ester oils selected from the group consisting of triethylhexanoin, ethylhexyl palmitate, di(octyldodecyl/phytosteryl/behenyl) lauroyl glutamate, and jojoba seed oil.

The content of the ester oil is not particularly limited as long as it is an amount sufficient to reduce the stickiness of the petrolatum and enable stable storage of the water-in-oil emulsion composition when used in combination with a silicone-based film-forming agent and a polyglycerin fatty acid ester, and is preferably 2.0% to 30.0% by mass, and more preferably 5.0% to 25.0% by mass, based on the total mass of the water-in-oil emulsion composition. If the content of the ester oil is less than 2.0% by mass, the stickiness of the petrolatum may not be sufficiently reduced, and if it exceeds 30.0% by mass, the storage stability of the water-in-oil emulsion composition may not be sufficient.

In the present invention, a preferred combination of a silicone film-forming agent, a polyglycerol fatty acid ester, and an ester oil is a combination of one or more silicone film-forming agents selected from the group consisting of trimethylsiloxysilicate and polypropylsilsesquioxane, one or more polyglycerol fatty acid esters selected from the group consisting of polyglyceryl-2 isostearate and polyglyceryl-6 polyricinoleate, and one or more ester oils selected from the group consisting of triethylhexanoin, ethylhexyl palmitate, di(octyldodecyl/phytosteryl/behenyl) lauroyl glutamate, and jojoba seed oil.
In addition, in the present invention, a more preferred combination of a silicone film-forming agent, a polyglycerol fatty acid ester, and an ester oil is a combination in which the silicone film-forming agent is trimethylsiloxysilicate and polypropylsilsesquioxane, the polyglycerol fatty acid ester is polyglyceryl-2 isostearate and polyglyceryl-6 polyricinoleate, and the ester oil is triethylhexanoin and ethylhexyl palmitate.
In the present invention, the content ratio of petrolatum to the silicone film-forming agent, polyglycerol fatty acid ester, and ester oil is, in terms of mass ratio (petrolatum: silicone film-forming agent: polyglycerol fatty acid ester: ester oil), preferably 1: 0.1 to 2.0: 0.1 to 1.3: 0.2 to 7.0, and more preferably 1: 0.1 to 1.0: 0.1 to 0.6: 0.5 to 2.5.

<Other additives>
The water-in-oil emulsion composition of the present invention may contain, in addition to the above-mentioned components, at least one of vinylpyrrolidone-based film-forming agents, acrylic-based film-forming agents (e.g., ammonium acrylates copolymer, etc.), hydrocarbon oils [e.g., mineral oil, (C13-15)alkane, isododecane, hydrogenated palm oil, etc.], silicone oils (e.g., cyclopentasiloxane), wax, antifoaming agents, pH adjusters, deodorants, moisturizing agents, stabilizers, preservatives, anti-inflammatory agents (e.g., azulene, etc.), ceramides (e.g., ceramide 2, etc.), and clay minerals (e.g., disteardimonium hectorite, etc.), within the scope of the object of the present invention.
In addition, one embodiment of the present invention is also preferably an embodiment that does not contain one or more sunscreen ingredients such as titanium oxide and zinc oxide.

Examples of the vinylpyrrolidone-based film-forming agent include (VP/hexadecene) copolymer and (VP/eicosene) copolymer, and preferably (VP/hexadecene) copolymer. The vinylpyrrolidone-based film-forming agent may be used alone or in combination of two or more kinds.
When the water-in-oil emulsion composition of the present invention contains a vinylpyrrolidone-based film-forming agent, the content of the vinylpyrrolidone-based film-forming agent is not particularly limited, but is preferably 0.1% by mass to 5.0% by mass, and more preferably 0.3% by mass to 3.0% by mass, based on the total mass of the water-in-oil emulsion composition.

Examples of the wax include rice bran wax, carnauba wax, and candelilla wax. The wax may be used alone or in combination of two or more kinds.
When the water-in-oil emulsion composition of the present invention contains wax, the wax content is not particularly limited, but is preferably 0.1% by mass to 5.0% by mass, and more preferably 0.3% by mass to 3.0% by mass, based on the total mass of the water-in-oil emulsion composition.

The antifoaming agent may be a silicone-based antifoaming agent such as dimethicone (dimethylpolysiloxane), and the like. One type of antifoaming agent may be used alone, or two or more types may be used.
When the water-in-oil emulsion composition of the present invention contains an antifoaming agent, the content of the antifoaming agent is not particularly limited, but is preferably 0.01% by mass to 5.0% by mass, and more preferably 0.1% by mass to 3.0% by mass, based on the total mass of the water-in-oil emulsion composition.

Examples of the pH adjuster include citric acid, sodium citrate (Na citrate), anhydrous citric acid, lactic acid, sodium lactate, succinic acid, sodium succinate, disodium succinate, phosphoric acid, sodium dihydrogen phosphate, anhydrous disodium hydrogen phosphate, sodium hydroxide, and potassium hydroxide. The pH adjusters may be used alone or in combination of two or more.
When the water-in-oil emulsion composition of the present invention contains a pH adjuster, the content of the pH adjuster is not particularly limited, but is preferably 0.01% by mass to 5.0% by mass, and more preferably 0.05% by mass to 2.0% by mass, based on the total mass of the water-in-oil emulsion composition.

Examples of the deodorant include hydroxypropyl-β-cyclodextrin, α-cyclodextrin, β-cyclodextrin, γ-cyclodextrin, and methyl-β-cyclodextrin. The deodorant may be used alone or in combination of two or more kinds.
When the water-in-oil emulsion composition of the present invention contains a deodorant, the content of the deodorant is not particularly limited, but is preferably 0.01% by mass to 10.0% by mass, and more preferably 0.1% by mass to 3.0% by mass, based on the total mass of the water-in-oil emulsion composition.

Examples of moisturizing agents include glycerin, concentrated glycerin, hyaluronic acid, sodium hyaluronate (Na hyaluronate), betaine, 1,3-butylene glycol, dipropylene glycol, propylene glycol, polyethylene glycol, and aloe vera juice. These moisturizing agents may be used alone or in combination of two or more.
When the water-in-oil emulsion composition of the present invention contains a humectant, the content of the humectant is not particularly limited, but is preferably 0.1% by mass to 50.0% by mass, and more preferably 1.0% by mass to 20.0% by mass, based on the total mass of the water-in-oil emulsion composition.

The stabilizer may be magnesium sulfate, and one type of stabilizer may be used alone, or two or more types of stabilizers may be used.
When the water-in-oil emulsion composition of the present invention contains a stabilizer, the content of the stabilizer is not particularly limited, but is preferably 0.01% by mass to 5.0% by mass, and more preferably 0.1% by mass to 2.0% by mass, based on the total mass of the water-in-oil emulsion composition.

Examples of preservatives include phenoxyethanol, ethylhexylglycerin, and parabens [e.g., methylparaben (methyl paraoxybenzoate), ethylparaben (ethyl paraoxybenzoate), and propylparaben (propyl paraoxybenzoate)]. These preservatives may be used alone or in combination of two or more kinds.
When the water-in-oil emulsion composition of the present invention contains a preservative, the content of the preservative is not particularly limited, but is preferably 0.1% by mass to 3.0% by mass, and more preferably 0.2% by mass to 1.5% by mass, based on the total mass of the water-in-oil emulsion composition.

The content of water (e.g., purified water, deionized water, etc.) in the water-in-oil emulsion composition of the present invention is the remainder obtained by subtracting the total amount of the above-mentioned components from the total amount (100% by mass) of the water-in-oil emulsion composition.
The water content in the water-in-oil emulsion composition of the present invention is not particularly limited, but an example is 20.0 mass % to 85.0 mass %, preferably 25.0 mass % to 75.0 mass %, and more preferably 30.0 mass % to 65.0 mass %, based on the total mass of the water-in-oil emulsion composition.

The method for preparing the water-in-oil emulsion composition of the present invention is not particularly limited, but examples include a method in which an oil-soluble component containing petrolatum, a silicone-based film-forming agent, a polyglycerol fatty acid ester, an ester oil, and, if necessary, any optional components, and a water-soluble component are separately prepared, and the oil-soluble component and the water-soluble component are emulsified.
The resulting water-in-oil emulsion composition can be adjusted to a desired pH by adding a pH adjuster as necessary.
As the pH adjuster, for example, those mentioned above can be used.
The pH of the water-in-oil emulsion composition of the present invention is not particularly limited, but is preferably pH 3 or higher, more preferably pH 4 to pH 8, and even more preferably pH 4.5 to pH 7.

The formulation of the water-in-oil emulsion composition of the present invention is not particularly limited, but is preferably a cream, emulsion, or lotion, and more preferably a cream.

The use of the water-in-oil emulsion composition of the present invention is not particularly limited, but it is preferably used as a skin protective agent, and more preferably used as a skin protective agent for preventing or treating diaper rash in elderly people, particularly elderly people who are bedridden and require care, and young children.
A preferred embodiment of the use of the water-in-oil emulsion composition of the present invention is as a care product.

There are no particular limitations on the areas where the water-in-oil emulsion composition of the present invention can be applied, but examples include areas that are prone to inflammation due to irritation from urine or feces when wearing a diaper, or areas that have already caused inflammation (e.g., areas that are prone to diaper rash or areas that have diaper rash), and specifically include the buttocks.

[Water repellent]
The present invention relates to
2.0% to 30.0% by weight of petrolatum, based on the total weight of the water repellent;
Silicone film-forming agents,
The present invention relates to a water repellent comprising a polyglycerol fatty acid ester and an ester oil.

The petrolatum, silicone-based film-forming agent, polyglycerol fatty acid ester and ester oil contained in the water repellent of the present invention are as described in the water-in-oil emulsion composition.
Furthermore, the water repellent of the present invention may contain, in addition to the silicone-based film-forming agent, polyglycerol fatty acid ester, and ester oil, other additives explained in the water-in-oil emulsion composition, provided such addition does not impair the object of the present invention.

The water repellent of the present invention may contain water such as purified water or deionized water in addition to the above-mentioned components.
When the water repellent of the present invention contains water, the content of water is the remainder obtained by subtracting the total amount of the above-mentioned components from the total amount of the water repellent (100 mass %).
The water content in the water repellent of the present invention is not particularly limited, but an example is 20.0 mass% to 85.0 mass% based on the total mass of the water repellent, preferably 25.0 mass% to 75.0 mass%, and more preferably 30.0 mass% to 65.0 mass%.

The method for preparing the water repellent of the present invention is not particularly limited, but examples thereof include a method of preparing an oil-soluble component containing petrolatum, a silicone-based film-forming agent, a polyglycerin fatty acid ester, an ester oil, and an optional component as required, and a water-soluble component, and mixing the oil-soluble component and the water-soluble component, a method of mixing petrolatum, a silicone-based film-forming agent, a polyglycerin fatty acid ester, and an ester oil, and an optional component and water as required, and dissolving each component by heating, stirring, etc., as required, or a method of preparing a solution in which at least one of the essential components is dispersed or dissolved, a solution in which the remaining essential components are dispersed or dissolved, and a solution in which the optional components are dispersed or dissolved, and mixing these solutions, and dissolving each component by heating, stirring, etc. as required. In one aspect of the present invention, instead of dissolving each of the above-mentioned components, each component may be emulsified or uniformly dispersed, and therefore, the "method of dissolving each component" may be read as the "method of emulsifying or uniformly dispersing each component".
The resulting water repellent can be adjusted to a desired pH by adding a pH adjuster as necessary.
As the pH adjuster, for example, the pH adjusters explained in the water-in-oil emulsion composition can be used.
The pH of the water repellent of the present invention is not particularly limited, but is preferably 3 or more, more preferably 4 to 8, and even more preferably 4.5 to 7.

The application site of the water repellent of the present invention is as explained for the water-in-oil emulsion composition.
The form of the water repellent of the present invention is not particularly limited, but it is preferably in the form of a cream.
The use of the water repellent of the present invention is not particularly limited, but it is preferably used for the prevention or treatment of diaper rash in elderly people, particularly elderly people who are bedridden and require care, and infants.

The present invention will be explained in more detail below with reference to examples, but the present invention is not limited to the following examples.

[Example 1: Preparation of water-in-oil emulsion composition (water repellent)]
A water-in-oil emulsion composition (water repellent) having the composition shown in Table 1 was prepared.
Specifically, after dissolving silicone-based film-forming agent in ester oil, dissolve oil-soluble components such as polyglycerol fatty acid ester and petrolatum, and if necessary, heat to about 80°C, and stir using a stirrer.Separately, dissolve various water-soluble components such as moisturizer in water, and if necessary, heat to about 80°C, and after confirming that the various water-soluble components are completely dissolved, use a homomixer to gradually add this to the solution in which silicone-based film-forming agent is dissolved, and emulsify.Cool appropriately, and prepare water-in-oil type emulsion composition (water repellent) of each formulation.
Comparative Example 1 is a commercially available cream containing petrolatum as the main component (98.8% by mass) (hereinafter also referred to as "Commercial Product A"), and Comparative Example 2 is petrolatum. The amount of each component in the table represents the mass % based on the total mass of the composition (water repellent).

[Test Example 1: Tackiness (stickiness) test]
0.10 g of the sample was weighed out and evenly applied to artificial skin (Skin Texture Model STM-01, manufactured by Trinity Lab Co., Ltd.) to prepare a measurement sample. Next, the tackiness was measured under the conditions shown below using a static and dynamic friction tester (model: TL201Tt, manufactured by Trinity Lab Co., Ltd.) and the measurement sample. The results are shown in Table 2.
<Conditions for measuring tackiness>
Measurement type: Up-down sliding type Contactor: Tactile contactor Measurement speed (mm/sec): 0.2
Measurement distance (mm): 1
Number of measurements (round trip): 1

Results: In order to compare the tackiness between the samples, when the tackiness (average value) of Vaseline (Comparative Example 2) was taken as 1.0, the tackiness ratio of the water-in-oil emulsion composition (water repellent) of the present invention was 0.4, which was less than half of the tackiness of Vaseline. On the other hand, the tackiness ratio of Comparative Example 1 (commercial product A) was 1.8, which was significantly higher than the tackiness of Comparative Example 2 (Vaseline).
That is, it was revealed that the water-in-oil emulsion composition (water repellent) of the present invention has significantly lower tackiness and is less sticky than the commercially available product A (Comparative Example 1) and Vaseline (Comparative Example 2).

[Test Example 2: Stability test based on the content of petrolatum]
Water-in-oil emulsion compositions (water repellents) having the compositions shown in Table 3 were prepared in accordance with the method of Example 1. The amount of each component in the table represents mass % based on the total mass of the composition (water repellent).
The water-in-oil emulsion composition (water repellent) used in the evaluation test was transferred to a sealed glass container, and the sealed container was left under each environmental condition, and the storage stability of the water-in-oil emulsion composition (water repellent) was comprehensively evaluated visually according to the following evaluation criteria.
[conditions]
(1) Evaluate after leaving the sealed container at 0°C for 3 months.
(2) Evaluate after leaving the sealed container at room temperature for 3 months.
(3) The sealed container was left at 40°C and 75% humidity for 3 months and then evaluated.
(4) Evaluate after leaving the sealed container at 50°C for 3 months.
(5) The sealed container is placed in a 0°C incubator, the temperature is raised to 45°C over 8 hours, and then maintained at 45°C for 16 hours. The temperature is then lowered to 0°C over 8 hours, and then maintained at 0°C for 16 hours. The sealed container is then removed from the incubator and evaluated. [Evaluation criteria]
◯: No separation, precipitation, or significant coloration was observed under any of the conditions, and the state immediately after preparation was maintained.
×: One or more of separation, precipitation, significant coloration, etc. was observed under any of the conditions.

Results: By using a combination of petrolatum, a silicone-based film-forming agent, a polyglycerol fatty acid ester, and an ester oil, the storage stability of the water-in-oil emulsion composition (water repellent) was good even when the petrolatum content was 12.00% by mass.

[Test Example 3: Stability test using film-forming agent]
Water-in-oil emulsion compositions (water repellents) having the compositions shown in Table 4 were prepared in accordance with the method of Example 1, and the storage stability of the water-in-oil emulsion compositions (water repellents) prepared in the same manner as in Test Example 2 was evaluated. The amount of each component in the table represents mass % based on the total mass of the composition (water repellent).

Results: Water-in-oil emulsion compositions (water repellents) containing silicone-based film-forming agents such as trimethylsiloxysilicate, polypropylsilsesquioxane, (acrylates/dimethicone) copolymer, and (norbornene/tris(trimethylsiloxy)silylnorbornene) copolymer had good storage stability. On the other hand, water-in-oil emulsion compositions (water repellents) containing film-forming agents other than silicone-based film-forming agents showed one or more of the following symptoms: separation, precipitation, or significant coloration, and had poor storage stability.

[Test Example 4: Stability test using polyglycerol fatty acid ester]
According to the method of Example 1, water-in-oil emulsion compositions (water repellents) having the compositions shown in Table 5 were prepared, and the storage stability of the water-in-oil emulsion compositions (water repellents) prepared in the same manner as in Test Example 2 was evaluated.
The amount of each component in the table represents mass % based on the total mass of the composition (water repellent).

Results: Water-in-oil emulsion compositions (water repellents) containing polyglycerin fatty acid esters such as polyglyceryl-6 polyricinoleate, polyglyceryl-2 isostearate, and polyglyceryl-2 oleate had good storage stability. On the other hand, water-in-oil emulsion compositions (water repellents) containing silicone polymers or alkyl glyceryl ethers instead of polyglycerin fatty acid esters showed one or more of the following symptoms: separation, precipitation, or significant coloration, and had poor storage stability.

[Test Example 5: Water repellency test]
A certain amount of food coloring (red) dissolved in water was taken and applied to artificial skin (2.5 cm x 2.5 cm). After a few minutes, water, the water-in-oil emulsion composition of Example 1 (water repellent), a commercially available water-repellent skin care cream that does not contain petrolatum (hereinafter also referred to as "commercial product B"), and petrolatum (Comparative Example 2) were separately applied to the surface of the artificial skin to which the food coloring (red) had been applied, and the entire surface of the artificial skin was blended. After 8 hours and 24 hours, the artificial skin was immersed in 30 mL of water and stirred in a beaker for about 20 seconds to extract the coloring. The absorbance of the extract was then measured. The results of the absorbance measurement are shown in FIG. 1. Also, a photograph of the artificial skin after 8 hours (artificial skin washed with water) is shown in FIG. 2.
From the absorbance measurement results, the water-in-oil emulsion composition (water repellent) of Example 1 has a smaller absorbance value than water, and is considered to have a sufficient water repellent effect even after 8 hours and 24 hours. In addition, the water-in-oil emulsion composition (water repellent) of Example 1 has a better water repellent effect than commercial product B, and it was confirmed that the water repellent effect of the water-in-oil emulsion composition (water repellent) of Example 1 is the same as that of Vaseline (Comparative Example 2). In addition, since the absorbance after 24 hours was almost the same as that after 8 hours, it was confirmed that the water repellent effect of the water-in-oil emulsion composition (water repellent) of Example 1 continues.

[Test Example 6: Home Use Test (1)]
A home use test was conducted on 32 care recipients using the water-in-oil emulsion composition (water repellent) of Example 1 and commercial product A (Comparative Example 1). Commercial product A (Comparative Example 1) was used for 5 to 7 days, followed by a 5-day non-use period, after which the water-in-oil emulsion composition (water repellent) of Example 1 was used for 5 to 7 days, after which a questionnaire survey was conducted. The application sites of commercial product A and the water-in-oil emulsion composition (water repellent) were the buttocks of the care recipients. The results are shown in FIG. 3.
3, the water-in-oil emulsion composition (water repellent) of the present invention was rated as having the same level of protective (water-repellent) effect as the commercially available product A, but the water-in-oil emulsion composition (water repellent) of the present invention was rated higher in terms of usability such as moist feeling, spreadability, stickiness, and smooth feeling than the commercially available product A. In other words, the water-in-oil emulsion composition (water repellent) of the present invention has the same level of water repellency as the commercially available product A, which contains petrolatum as the main component (98.8% by mass), but has a better usability than the commercially available product A.
In addition, among the above results, the fact that the water-in-oil emulsion composition (water repellent) of the present invention is superior in stickiness and smoothness to the commercially available product A is consistent with the results of the tackiness (stickiness) test shown in Table 2.

[Test Example 7: Home Use Test (2)]
A home use test was conducted on 32 care recipients using the water-in-oil emulsion composition (water repellent) of Example 1 and commercially available product B. After using commercially available product B for 5 to 7 days and then leaving a 5-day non-use period, the water-in-oil emulsion composition (water repellent) of Example 1 was used for 5 to 7 days, after which a questionnaire survey was conducted. The areas where commercially available product B and the water-in-oil emulsion composition (water repellent) were applied were the buttocks of the care recipients. The results are shown in Figure 4.
4, the water-in-oil emulsion composition (water repellent) of the present invention was evaluated as being about the same as commercially available product B in terms of spreadability, but the water-in-oil emulsion composition (water repellent) of the present invention was evaluated as being higher in terms of protective (water repellent) effect and moist feeling (moisturizing power) than commercially available product B. In other words, the water-in-oil emulsion composition (water repellent) of the present invention has a similar feel when used as commercially available product B, which is a water-repellent skin care cream that does not contain petrolatum, but has better water repellency than said commercially available product B.
In addition, among the above results, the fact that the water-in-oil emulsion composition (water repellent) of the present invention has a superior protective (water repellent) effect compared to the commercially available product B is consistent with the results of Test Example 5.

Claims (13)

2.0% to 30.0% by mass of petrolatum based on the total mass of the water-in-oil emulsion composition;
Silicone film-forming agents,
A water-in-oil emulsion composition comprising a polyglycerol fatty acid ester and an ester oil. The water-in-oil emulsion composition according to claim 1, wherein the silicone-based film-forming agent is one or more silicone-based film-forming agents selected from the group consisting of trimethylsiloxysilicate, polypropylsilsesquioxane, (acrylates/dimethicone) copolymer, (norbornene/tris(trimethylsiloxy)silylnorbornene) copolymer, tri(trimethylsiloxy)silylpropylcarbamic acid pullulan, (acrylates/polytrimethylsiloxy methacrylate) copolymer, and (trimethylsiloxysilicate/dimethiconol) crosspolymer. The water-in-oil emulsion composition according to claim 1, wherein the polyglycerol fatty acid ester is one or more polyglycerol fatty acid esters selected from the group consisting of polyglyceryl-2 isostearate, polyglyceryl-2 oleate, polyglyceryl-6 polyricinoleate, polyglyceryl-10 polyricinoleate, polyglyceryl-10 pentahydroxystearate, polyglyceryl-10 pentaisostearate, polyglyceryl-6 pentaoleate, and polyglyceryl-10 pentaoleate. The water-in-oil emulsion composition according to claim 1, wherein the ester oil is one or more ester oils selected from the group consisting of triethylhexanoin, ethylhexyl palmitate, octyldodecyl myristate, di(octyldodecyl/phytosteryl/behenyl) lauroyl glutamate, jojoba seed oil, and tri(caprylic/capric)glyceryl. the silicone-based film-forming agent is one or more silicone-based film-forming agents selected from the group consisting of trimethylsiloxysilicate and polypropylsilsesquioxane;
The polyglycerol fatty acid ester is one or more polyglycerol fatty acid esters selected from the group consisting of polyglyceryl-2 isostearate and polyglyceryl-6 polyricinoleate,
The ester oil is one or more ester oils selected from the group consisting of triethylhexanoin, ethylhexyl palmitate, di(octyldodecyl/phytosteryl/behenyl) lauroyl glutamate, and jojoba seed oil.
The water-in-oil emulsion composition according to claim 1. The water-in-oil emulsion composition according to claim 1, wherein the water-in-oil emulsion composition is in the form of a cream. 2.0% to 30.0% by weight of petrolatum, based on the total weight of the water repellent;
Silicone film-forming agents,
A water repellent comprising a polyglycerol fatty acid ester and an ester oil. The water repellent according to claim 7, wherein the silicone-based film-forming agent is one or more silicone-based film-forming agents selected from the group consisting of trimethylsiloxysilicate, polypropylsilsesquioxane, (acrylates/dimethicone) copolymer, (norbornene/tris(trimethylsiloxy)silylnorbornene) copolymer, tri(trimethylsiloxy)silylpropylcarbamic acid pullulan, (acrylates/polytrimethylsiloxy methacrylate) copolymer, and (trimethylsiloxysilicate/dimethiconol) crosspolymer. The water repellent according to claim 7, wherein the polyglycerol fatty acid ester is one or more polyglycerol fatty acid esters selected from the group consisting of polyglyceryl-2 isostearate, polyglyceryl-2 oleate, polyglyceryl-6 polyricinoleate, polyglyceryl-10 polyricinoleate, polyglyceryl-10 pentahydroxystearate, polyglyceryl-10 pentaisostearate, polyglyceryl-6 pentaoleate, and polyglyceryl-10 pentaoleate. The water repellent according to claim 7, wherein the ester oil is one or more ester oils selected from the group consisting of triethylhexanoin, ethylhexyl palmitate, octyldodecyl myristate, di(octyldodecyl/phytosteryl/behenyl) lauroyl glutamate, jojoba seed oil, and tri(caprylic/capric)glyceryl. the silicone-based film-forming agent is one or more silicone-based film-forming agents selected from the group consisting of trimethylsiloxysilicate and polypropylsilsesquioxane;
The polyglycerol fatty acid ester is one or more polyglycerol fatty acid esters selected from the group consisting of polyglyceryl-2 isostearate and polyglyceryl-6 polyricinoleate,
The ester oil is one or more ester oils selected from the group consisting of triethylhexanoin, ethylhexyl palmitate, di(octyldodecyl/phytosteryl/behenyl) lauroyl glutamate, and jojoba seed oil.
The water repellent according to claim 7. The water-in-oil emulsion composition according to claim 1, for use in skin protection. The water-in-oil emulsion composition according to claim 1, which is used as a care product.

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