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WO2022173247A3 - 클로렐라(Chlorella sp.)추출물 및 이의 페오피틴화 분획물 또는 이로부터 수득한 폴피린계 또는 카로테논계 화합물을 유효성분으로 포함하는 신종코로나 바이러스 감염의 예방 또는 치료용 조성물 - Google Patents

클로렐라(Chlorella sp.)추출물 및 이의 페오피틴화 분획물 또는 이로부터 수득한 폴피린계 또는 카로테논계 화합물을 유효성분으로 포함하는 신종코로나 바이러스 감염의 예방 또는 치료용 조성물 Download PDF

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Publication number
WO2022173247A3
WO2022173247A3 PCT/KR2022/002046 KR2022002046W WO2022173247A3 WO 2022173247 A3 WO2022173247 A3 WO 2022173247A3 KR 2022002046 W KR2022002046 W KR 2022002046W WO 2022173247 A3 WO2022173247 A3 WO 2022173247A3
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Prior art keywords
carotenone
porphyrin
prevention
treatment
based compound
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PCT/KR2022/002046
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English (en)
French (fr)
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WO2022173247A2 (ko
Inventor
오원근
이바울
초효문
폰스호르헤
최영기
김은하
김세미
Original Assignee
서울대학교산학협력단
충북대학교 산학협력단
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Publication of WO2022173247A2 publication Critical patent/WO2022173247A2/ko
Publication of WO2022173247A3 publication Critical patent/WO2022173247A3/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02—Algae
    • A61K36/05—Chlorophycota or chlorophyta (green algae), e.g. Chlorella
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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    • A01N35/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical
    • A01N35/04—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical containing aldehyde or keto groups, or thio analogues thereof, directly attached to an aromatic ring system, e.g. acetophenone; Derivatives thereof, e.g. acetals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/03—Algae
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/409—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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    • A23V2200/00—Function of food ingredients
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    • A23V2200/324—Foods, ingredients or supplements having a functional effect on health having an effect on the immune system
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2250/00—Food ingredients
    • A23V2250/20—Natural extracts
    • A23V2250/202—Algae extracts
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2250/00—Food ingredients
    • A23V2250/30—Other Organic compounds

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  • Health & Medical Sciences (AREA)
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  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
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  • Wood Science & Technology (AREA)
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  • Epidemiology (AREA)
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  • Alternative & Traditional Medicine (AREA)
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  • Gastroenterology & Hepatology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Pest Control & Pesticides (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

본 발명은 클로렐라(Chlorella sp.)추출물 및 페오피틴화 분획물 또는 이로부터 분리한 폴피린계 또는 카로테논계 화합물을 유효성분으로 포함하는 신종코로나 바이러스 감염의 예방 또는 치료용 조성물에 관한 것으로, 화학적 방법을 통하여 활성화합물인 폴피린계 화합물인 페오피틴 A(화합물 1)과 페오피틴 B(화합물 2)의 함량을 높이고 또한 카로테논계 화합물을 더 포함함으로써 항바이러스 활성의 상승작용을 통하여 특히 사람의 신종코로나 바이러스 감염의 치료와 예방에 유용하게 이용될 수 있다.
PCT/KR2022/002046 2021-02-10 2022-02-10 클로렐라(Chlorella sp.)추출물 및 이의 페오피틴화 분획물 또는 이로부터 수득한 폴피린계 또는 카로테논계 화합물을 유효성분으로 포함하는 신종코로나 바이러스 감염의 예방 또는 치료용 조성물 WO2022173247A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020210019462A KR102583001B1 (ko) 2021-02-10 2021-02-10 클로렐라(Chlorella sp.)추출물 및 이의 페오피틴화 분획물 또는 이로부터 수득한 폴피린계 또는 카로테논계 화합물을 유효성분으로 포함하는 신종코로나 바이러스 감염의 예방 또는 치료용 조성물
KR10-2021-0019462 2021-02-10

Publications (2)

Publication Number Publication Date
WO2022173247A2 WO2022173247A2 (ko) 2022-08-18
WO2022173247A3 true WO2022173247A3 (ko) 2022-10-06

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PCT/KR2022/002046 WO2022173247A2 (ko) 2021-02-10 2022-02-10 클로렐라(Chlorella sp.)추출물 및 이의 페오피틴화 분획물 또는 이로부터 수득한 폴피린계 또는 카로테논계 화합물을 유효성분으로 포함하는 신종코로나 바이러스 감염의 예방 또는 치료용 조성물

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KR (1) KR102583001B1 (ko)
WO (1) WO2022173247A2 (ko)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11322753A (ja) * 1998-05-08 1999-11-24 Masaki Kamata 新規な活性フェオフィチン化合物、その製造法及び用途
US20110217244A1 (en) * 2007-10-26 2011-09-08 National Research Council Of Canada Compositions and methods for enhancing immune response
JP2016065037A (ja) * 2014-09-17 2016-04-28 株式会社日健総本社 抗ウイルス剤の製法及び該製法によって得られた抗ウイルス剤
JP2017160180A (ja) * 2016-03-04 2017-09-14 株式会社ユーグレナ 抗ウイルス剤及び抗ウイルス用食品

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102176525B1 (ko) 2018-11-07 2020-11-10 한국과학기술원 희생층을 이용한 계층적 주름 구조체의 제조방법 및 이로부터 제조된 계층적 주름 구조체
KR102169476B1 (ko) 2020-05-20 2020-10-23 (주)신테카바이오 제2형 중증급성호흡기증후군 코로나바이러스 감염 질환의 예방 또는 치료용 조성물
KR20200131784A (ko) 2020-11-04 2020-11-24 (주)신테카바이오 제2형 중증급성호흡기증후군 코로나바이러스 감염 질환의 예방 또는 치료용 조성물

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11322753A (ja) * 1998-05-08 1999-11-24 Masaki Kamata 新規な活性フェオフィチン化合物、その製造法及び用途
US20110217244A1 (en) * 2007-10-26 2011-09-08 National Research Council Of Canada Compositions and methods for enhancing immune response
JP2016065037A (ja) * 2014-09-17 2016-04-28 株式会社日健総本社 抗ウイルス剤の製法及び該製法によって得られた抗ウイルス剤
JP2017160180A (ja) * 2016-03-04 2017-09-14 株式会社ユーグレナ 抗ウイルス剤及び抗ウイルス用食品

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
KAPEWANGOLO PETRINA, KANDAWA-SCHULZ MARTHA, MEYER DEBRA: "Anti-HIV Activity of Ocimum labiatum Extract and Isolated Pheophytin-a", MOLECULES, vol. 22, no. 11, pages 1763, XP055973690, DOI: 10.3390/molecules22111763 *

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KR20220115759A (ko) 2022-08-18
WO2022173247A2 (ko) 2022-08-18
KR102583001B1 (ko) 2023-09-27

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