WO2019184308A1

WO2019184308A1 - Blood fat-reducing and blood pressure-reducing health care tea and preparation method therefor

Info

Publication number: WO2019184308A1
Application number: PCT/CN2018/110824
Authority: WO
Inventors: 张丽珠; 叶勇
Original assignee: 华南理工大学
Priority date: 2018-03-29
Filing date: 2018-10-18
Publication date: 2019-10-03
Also published as: CN108552373A

Abstract

A blood fat-reducing and blood pressure-reducing health care tea and a preparation method therefor. The health care tea is prepared by means of the following raw materials in parts by weight: sandalwood leaf 10-40, lupin leaf 10-30, moringa seed leaf 10-30, chickpea leaf 10-30, sandalwood seed 5-20, moringa seed 5-20, lupin 5-20, and chickpea 5-20. The preparation method comprises: extracting, filtering, precipitating, and re-filtering the sandalwood leaf, lupin leaf, moringa seed leaf, chickpea leaf, sandalwood seed, moringa seed, lupin, and chickpea by using water; drying a filtrate to obtain a blood fat-reducing and blood pressure-reducing health care tea.

Description

Blood fat lowering and blood pressure lowering health-care tea and preparation method thereof

Technical field

The invention belongs to the technical field of health drinks, and particularly relates to a health tea with hypolipidemic and blood pressure lowering effects and a preparation method of the health tea.

Background technique

Hyperlipidemia and hypertension are the most common cardiovascular and cerebrovascular diseases in China. Hyperlipidemia can induce high blood pressure, and high blood pressure causes multiple organs to be involved, resulting in serious complications. Most of the drugs that lower blood pressure are chemical drugs, mainly through the expansion of blood vessels, diuretic and other mandatory control symptoms, but will eventually accelerate organ damage, and can lead to increased blood lipids, senile dementia and other adverse reactions. Traditional Chinese medicine plays an important role in the prevention and treatment of hyperlipidemia and hypertension. Chinese medicine believes that hypertension is caused by liver yang sputum, liver and kidney yin deficiency, and it is appropriate to clear liver fire and liver and kidney. However, the use of traditional Chinese medicine is inconvenient, the taste is not good, and long-term application also has certain toxic side effects.

Most of the health teas use traditional Chinese medicines with the same medicine and food. They have no toxic and side effects for long-term consumption, and because of low concentration and good taste, they are the best choice for prevention of hyperlipidemia and hypertension. At present, there are some market products for lowering blood fat and lowering blood pressure health tea, but the effect is still unsatisfactory and cannot meet the increasing social demand.

Summary of the invention

In order to overcome the shortcomings and deficiencies of the prior art, it is an object of the present invention to provide a blood fat lowering and blood pressure lowering health care tea. The health tea of the invention has sandalwood leaves as a main component, and the health tea of the invention has the effects of lowering blood pressure and lowering blood fat by synergistic with other components, and the effect is remarkable; and the health tea of the invention is convenient to use and taste. suitable.

Another object of the present invention is to provide a method for preparing the above-mentioned hypolipidemic and blood pressure lowering health care tea.

The invention is based on the understanding and treatment principle of the motherland medicine on the pathogenesis of hypertension and hyperlipemia, and screens out the natural botanical drugs for clearing away liver heat and nourishing liver and kidney, according to the theory of Chinese medicine, to achieve preventive health care and auxiliary treatment of hypertension. The purpose of high blood lipid disease.

The object of the invention is achieved by the following technical solutions:

A hypolipidemic and blood pressure lowering health tea prepared from the following raw materials in parts by weight: sandalwood leaves 10 to 40, lupin leaves 10 to 30, Moringa seed leaves 10 to 30, chickpea leaves 10 ~ 30, sandalwood seeds 5 ~ 20, lupin 5 ~ 20, Moringa seeds 5 ~ 20, chickpeas 5 ~ 20.

The hypolipidemic and blood pressure lowering health tea is an aqueous extract of sandalwood leaves, lupin leaves, moringa seed leaves, chickpea leaves, sandalwood seeds, lupins, moringa seeds, and chickpeas.

The preparation method of the hypolipidemic and blood pressure lowering health tea comprises the following steps:

Sandalwood leaves, lupin leaves, moringa seed leaves, chickpea leaves, sandalwood seeds, lupins, moringa seeds, and chickpeas are extracted with water, filtered, precipitated, filtered again, and the filtrate is dried to obtain Lowering blood fat and lowering blood pressure health tea.

The extraction temperature is 60 to 100 ° C, and the extraction time is 1 to 3 h.

The mass ratio of the water to the total amount of the raw materials is (8-20): 1, and the raw materials are sandalwood leaves, lupin leaves, moringa seed leaves, chickpea leaves, sandalwood seeds, lupins, moringa seeds, and Chickpeas.

The precipitated precipitant is ethanol; the precipitant is added in an amount that the precipitant is added to the filtered filtrate, and the volume fraction of the precipitant is 60 to 85%.

The sandalwood leaves, lupin leaves, moringa seed leaves, chickpea leaves, sandalwood seeds, lupins, moringa seeds, and chickpeas are pulverized and sieved before being extracted; The number of meshes is 10 to 40 mesh.

The precipitation time is 12 to 24 hours.

The drying is spray drying, vacuum drying or freeze drying, preferably spray drying (good particle size).

The temperature of the spray drying is 150 to 220 ° C; the temperature of the vacuum drying is 50 to 80 ° C, and the temperature of the freeze drying is -30 to -50 ° C.

Filter again and recover the precipitant before drying the filtrate. The recovery is vacuum distillation and condensation.

The invention adopts the composition of sandalwood leaves and edible plant parts, and has no toxic and side effects. The use of sandalwood leaves for clearing liver heat, lupin's soothing and relieving stagnation, chickpea nourishing liver and kidney and moringa seed for protecting liver and strengthening kidney, reasonable composition, and extraction, taking the effective part of flavonoids, enhancing Reduce blood fat and lower blood pressure. The source and efficacy of each group are as follows:

Sandalwood: Sandalwood sandalwood is a perennial tree distributed in India, Malaysia, Australia and Indonesia. It is cultivated in Guangdong and Taiwan. Its heartwood is a valuable medicinal material and a valuable spice, but its leaves and fruits are less used. Sandalwood leaves are cool, can be dry and hot, rich in flavonoids and polysaccharides, with significant blood lipid lowering and hypoglycemic activity. The invention combines sandalwood leaves and sandalwood seeds with good flatness.

Lupin: The seed of the annual herb of the leguminous lupin, native to the Mediterranean region, cultivated in China. Its seeds contain higher protein and are generally used as feed. Its sexual taste is sweet, there are soothing and relieving depression, live serum swelling, and the effect of growing muscle and bone. The invention combines lupin leaves and lupins with good flatness.

Moringa seed: Moringa genus is a perennial tropical, subtropical deciduous tree seed, native to India, currently grown in Africa and the world's tropical and subtropical regions. Its leaves, flowers, tender pods and seeds can be eaten directly and contain a lot of nutrients. It is mild, mild and non-toxic, and has remarkable curative effect in lowering blood fat, blood pressure, regulating gastrointestinal, protecting liver and alcohol, and enhancing human immunity. The invention combines the Moringa seed and the Moringa seed with good flatness.

Chickpea: The seed of the annual herb of the genus Chickpea, native to western Asia, has been widely introduced all over the world. Its seeds are rich in protein and other nutrients and are edible plants. Sexually sweet, non-toxic, with Buzhong Yiqi, Wenshen impotence, treatment of diabetes, blood stasis, lungs and cough, physical fitness, enhance memory and so on. The invention combines the chickpea leaves and the chickpeas with a good taste.

Compared with the prior art, the present invention has the following advantages and beneficial effects:

The health tea of the invention is extracted from natural edible plants, has no toxic and side effects, has the effects of lowering blood pressure and lowering blood fat, has remarkable effects, and is also suitable for prevention of hyperlipemia and hypertension diseases; and the health tea of the invention is convenient to use and taste is suitable. .

detailed description

The present invention will be further described in detail below with reference to the embodiments, but the embodiments of the present invention are not limited thereto.

Example 1

A blood fat lowering and blood pressure lowering health tea prepared from the following raw materials:

20g of sandalwood leaves, 15g of lupin leaves, 15g of moringa seeds, 15g of chickpea leaves, 10g of sandalwood seeds, 10g of lupin, 10g of moringa seeds, 5g of chickpeas.

The above raw materials are pulverized through a 20 mesh sieve, 1000 g of hot water is added, and immersed for 2 hours at 90 ° C for filtration; ethanol is added to the filtrate until the volume fraction of ethanol is 75%, and then allowed to stand for 12 hours, and filtered; the ethanol in the filtrate is recovered, and then The filtrate after recovering ethanol was spray-dried at 180 ° C to obtain 15 g of hypolipidemic and blood pressure lowering health tea. The appearance of the health tea prepared in this embodiment is a light yellow powder, which can be directly dissolved by adding water, and has a pleasant taste and a fragrant taste.

Effect test: The health tea prepared in this example was taken for patients with hypertension and hyperlipidemia, 3 times a day, 3 g each time (equivalent to 30 g of crude drug), and continuously taken for 3 months. A total of 70 cases were observed, aged 35 to 65 years old, including 37 males and 33 females. The history of hypertension was 1 to 12 years. The blood pressure was 140-180/95-110 mmHg, and blood cholesterol and triglycerides were high. Has been taking antihypertensive drugs, but the effect is not good. After taking the health tea prepared in this example for 3 months, 67 people had different degrees of blood pressure and blood lipids, 43 people had normal blood pressure and blood lipids, and the effective rate was 96%.

Example 2

10g of sandalwood leaves, 10g of lupin leaves, 30g of moringa seeds, 10g of chickpea leaves, 5g of sandalwood seeds, 5g of lupin, 20g of Moringa seeds, 10g of chickpeas.

The above raw materials are pulverized through a 10-mesh sieve, 800 g of hot water is added, and the mixture is immersed for 1 hour at 100 ° C for filtration; ethanol is added to the filtrate to a volume fraction of ethanol of 60%, and then allowed to stand for 24 hours, and filtered; the ethanol in the filtrate is recovered, and then The filtrate after recovering ethanol was spray-dried at 220 ° C to obtain 12 g of hypolipidemic and blood pressure lowering health tea. The appearance of the health tea prepared in this embodiment is a light yellow powder, which can be directly dissolved by adding water, and has a pleasant taste and a fragrant taste. The test procedure of Example 1 was used for the trial of patients with hypertension and hyperlipidemia, and the effective rate was 90%.

Example 3

40g of sandalwood leaves, 20g of lupin leaves, 10g of moringa seeds, 10g of chickpea leaves, 5g of sandalwood seeds, 5g of lupin, 5g of moringa seeds, 5g of chickpeas.

The above raw materials are pulverized through a 40 mesh sieve, 2000 g of hot water is added, and immersed for 3 hours at 60 ° C for filtration, and ethanol is added to the filtrate to a volume fraction of ethanol of 80%, and then allowed to stand for 16 hours, and filtered; the ethanol in the filtrate is recovered, and then The filtrate after recovering ethanol was spray-dried at 200 ° C to obtain 17 g of hypolipidemic and blood pressure lowering health tea. The appearance of the health tea prepared in this embodiment is a light yellow powder, which can be directly dissolved by adding water, and has a pleasant taste and a fragrant taste.

The test procedure of Example 1 was used for the trial of patients with hypertension and hyperlipidemia, and the effective rate was 97%.

Example 4

15g of sandalwood leaves, 10g of lupin leaves, 10g of moringa seeds, 10g of chickpea leaves, 20g of sandalwood seeds, 15g of lupin, 10g of moringa seeds, 10g of chickpeas.

The above raw materials are pulverized through a 30 mesh sieve, 1200 g of hot water is added, and immersed for 1.5 hours at 70 ° C for filtration, and ethanol is added to the filtrate to a volume fraction of ethanol of 75%, and then allowed to stand for 18 hours, and filtered; the ethanol in the filtrate is recovered, and then The filtrate after recovering ethanol was spray-dried at 150 ° C to obtain 14 g of hypolipidemic and blood pressure lowering health tea. The appearance of the health tea prepared in this embodiment is a light yellow powder, which can be directly dissolved by adding water, and has a pleasant taste and a fragrant taste.

According to the effect test procedure of Example 1, the patients were tested for hypertension and hyperlipidemia, and the effective rate was 92%.

Example 5

10g of sandalwood leaves, 30g of lupin leaves, 15g of moringa seeds, 10g of chickpea leaves, 5g of sandalwood seeds, 5g of lupin, 5g of moringa seeds, 20g of chickpeas.

The above raw materials are pulverized through a 15 mesh sieve, 1400 g of hot water is added, and immersed for 2.5 hours at 90 ° C for filtration; ethanol is added to the filtrate to a volume fraction of ethanol of 65%, and then allowed to stand for 20 hours, and filtered; the ethanol in the filtrate is recovered, and then The filtrate after recovering ethanol was spray-dried at 210 ° C to obtain 16 g of hypolipidemic and blood pressure lowering health tea. The appearance of the health tea prepared in this embodiment is a light yellow powder, which can be directly dissolved by adding water, and has a pleasant taste and a fragrant taste.

The test procedure of Example 1 was used for the trial of patients with hypertension and hyperlipidemia, and the effective rate was 94%.

Example 6

Sandalwood leaves 25g, lupin leaves 10g, Moringa seed leaves 10g, chickpea leaves 10g, sandalwood seeds 5g, lupins 5g, Moringa seeds 15g, chickpeas 20g.

The above raw materials are pulverized through a 20 mesh sieve, 1800 g of hot water is added, and immersed for 3 hours at 70 ° C for filtration, and ethanol is added to the filtrate to a volume fraction of ethanol of 75%, and then allowed to stand for 15 hours, and filtered; the ethanol in the filtrate is recovered, and then The filtrate after recovering ethanol was spray-dried at 190 ° C to obtain 15 g of hypolipidemic and blood pressure lowering health tea. The health tea prepared in this embodiment has a pale yellow powder and can be directly dissolved by adding water, and has a pleasant taste and a fragrant taste.

The test procedure of Example 1 was used for the trial of patients with hypertension and hyperlipidemia, and the effective rate was 95%.

Comparative example

Synergies and taste comparison of leaves with seeds or beans:

a. Take sandalwood leaves, lupin leaves, moringa seed leaves, chickpea leaves, sandalwood seeds, lupins, moringa seeds, and chickpeas each 5g, respectively, add 200mL boiling water for brewing, soak for 30min and then filter. Take the filtrate to drink;

b. Mix 5g of sandalwood leaves, lupin leaves, moringa seed leaves, chickpea leaves, sandalwood seeds, and moringa seeds, add 1200mL boiling water, soak for 30min, filter, and take the filtrate to drink; Mixing soak with seed);

c, each 5g of sandalwood leaves, lupin leaves, Moringa seed leaves, chickpea leaves, lupins, chickpeas mixed, add 1200mL boiling water brewing, soak for 30min, filter, take the filtrate to drink; (leaf and beans Mix the soaking solution).

40 high blood pressure and hyperlipidemia volunteers were tried, 10 of them took leaf soaking solution, 10 people took seed or bean soaking solution, 10 people took leaf and seed mixed soaking solution, 10 people took leaf and bean mixed soaking liquid, and tasted Its taste. After 1 month, blood pressure, blood cholesterol and triglycerides were measured, and it was effective to reduce the blood pressure by 10% before and after taking.

Results: The effective rate of taking leaf soaking solution was 60% (such as: sandalwood leaves), the effective rate of taking seed or bean soaking solution was 40% (such as sandalwood seed), and the leaf and seed mixed soaking liquid was used. The efficiency is 80%, and the effective rate of taking the leaf and bean mixed soaking solution is 80%, indicating that the four plant leaves of the present invention have the synergistic effect of lowering blood pressure and lowering blood fat in combination with seeds or beans. Compared with the taste, sandalwood leaves, lupin leaves, Moringa seed leaves, and chickpea leaf soaking liquid are rich in flavor but bitter, while the seed and bean soaking liquid is light and sweet. After soaking, the soaking liquid has good aroma and no bitterness. , good entrance. It is indicated that the above four plant leaves are compatible with seeds or beans, which can improve the taste and is suitable for long-term drinking as a health drink.

Sandalwood leaves are bitter and bitter, while the seeds are warm and sweet. The active ingredients in sandalwood leaves and sandalwood seeds can lower blood fat and lower blood pressure.

The lupin leaves are bitter and bitter, while the seeds are warm and sweet. The active ingredients in lupin leaves and lupins can lower blood fat and lower blood pressure.

Moringa seed leaves are cool and bitter, while the seeds are warm and sweet. The active ingredients in Moringa seed and Moringa seed can lower blood fat and lower blood pressure.

The leaves of the chickpeas are bitter and bitter, while the seeds are warm and sweet. The active ingredients in the chickpea leaves and chickpeas can lower blood fat and lower blood pressure.

The above embodiments are preferred embodiments of the present invention, but the embodiments of the present invention are not limited to the above embodiments, and any other changes, modifications, substitutions, combinations, and combinations thereof may be made without departing from the spirit and scope of the invention. Simplifications should all be equivalent replacements and are included in the scope of the present invention.

Claims

The invention relates to a hypolipidemic and blood pressure lowering health-care tea, which is prepared by the following raw materials in parts by weight: sandalwood leaves 10-40, lupin leaves 10-30, Moringa seed leaves 10-30, eagle Mouth leaves 10 to 30, sandalwood seeds 5 to 20, lupins 5 to 20, Moringa seeds 5 to 20, and chickpeas 5 to 20.
The hypolipidemic and blood pressure lowering health tea according to claim 1, wherein the hypolipidemic and blood pressure lowering health tea is sandalwood leaf, lupin leaf, moringa seed leaf, chickpea leaf, sandalwood seed, Water extract of lupine, moringa seeds and chickpeas.
The method for preparing hypolipidemic and blood pressure lowering health-care tea according to any one of claims 1 to 2, comprising the steps of:

Sandalwood leaves, lupin leaves, moringa seed leaves, chickpea leaves, sandalwood seeds, lupins, moringa seeds, and chickpeas are extracted with water, filtered, precipitated, filtered again, and the filtrate is dried to obtain Lowering blood fat and lowering blood pressure health tea.
The method for preparing hypolipidemic and blood pressure lowering health tea according to claim 3, characterized in that:

The precipitated precipitant is ethanol.
The method for preparing hypolipidemic and blood pressure lowering health-care tea according to claim 4, wherein the amount of the precipitating agent added satisfies the following condition: the precipitating agent is added to the filtered filtrate, and the volume fraction of the precipitating agent is 60 to 85%.
The method for preparing hypolipidemic and blood pressure lowering health tea according to claim 3, characterized in that:

The extraction temperature is 60 to 100 ° C, and the extraction time is 1 to 3 h;

The mass ratio of the water to the total amount of the raw materials is (8-20): 1, and the raw materials are sandalwood leaves, lupin leaves, moringa seed leaves, chickpea leaves, sandalwood seeds, lupins, moringa seeds, and Chickpeas.
The method for preparing hypolipidemic and blood pressure lowering health-care tea according to claim 3, characterized in that the sandalwood leaf, lupin leaf, moringa seed leaf, chickpea leaf, sandalwood seed, lupin, moringa Seeds and chickpeas need to be comminuted and sieved before being extracted.
The method for preparing hypolipidemic and blood pressure lowering health-care tea according to claim 3, wherein the precipitation time is 12 to 24 hours;

The drying is spray drying, vacuum drying or freeze drying.
The method for preparing hypolipidemic and blood pressure lowering health-care tea according to claim 8, wherein the temperature of the spray drying is 150 to 220 ° C; the temperature of the vacuum drying is 50 to 80 ° C, the freeze-dried The temperature is -30 to -50 °C.
The method for preparing hypolipidemic and blood pressure lowering health-care tea according to claim 3, wherein the precipitating agent is recovered before being filtered again.