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WO2018115978A3 - Water-in-oil-in water emulsions for analysis of biological and chemical samples - Google Patents

Water-in-oil-in water emulsions for analysis of biological and chemical samples Download PDF

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Publication number
WO2018115978A3
WO2018115978A3 PCT/IB2017/001740 IB2017001740W WO2018115978A3 WO 2018115978 A3 WO2018115978 A3 WO 2018115978A3 IB 2017001740 W IB2017001740 W IB 2017001740W WO 2018115978 A3 WO2018115978 A3 WO 2018115978A3
Authority
WO
WIPO (PCT)
Prior art keywords
water
oil
biological
analysis
emulsions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2017/001740
Other languages
French (fr)
Other versions
WO2018115978A2 (en
Inventor
Mark Davies
Daniel Murphy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Limerick
Original Assignee
University of Limerick
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Limerick filed Critical University of Limerick
Publication of WO2018115978A2 publication Critical patent/WO2018115978A2/en
Publication of WO2018115978A3 publication Critical patent/WO2018115978A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/087—Multiple sequential chambers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

The invention provides water-in-oil-in-water emulsions having large water-in-oil droplets in which chemical or biological reactions can be conducted and analyzed. The invention also provides fluidic systems comprising water-in-oil-in-water emulsions contained within the channel of a substrate. Also provided are methods of making water-in-oil-in-water emulsions having large water-in-oil droplets.
PCT/IB2017/001740 2016-12-23 2017-12-19 Water-in-oil-in water emulsions for analysis of biological and chemical samples Ceased WO2018115978A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662438525P 2016-12-23 2016-12-23
US62/438,525 2016-12-23

Publications (2)

Publication Number Publication Date
WO2018115978A2 WO2018115978A2 (en) 2018-06-28
WO2018115978A3 true WO2018115978A3 (en) 2018-08-02

Family

ID=62148413

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2017/001740 Ceased WO2018115978A2 (en) 2016-12-23 2017-12-19 Water-in-oil-in water emulsions for analysis of biological and chemical samples

Country Status (1)

Country Link
WO (1) WO2018115978A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020227321A1 (en) * 2019-05-07 2020-11-12 The Regents Of The University Of California Monodisperse emulsions templated by three-dimensional structured microparticles and methods of making the same
CN110694704B (en) * 2019-09-26 2021-10-12 安徽省昂普拓迈生物科技有限责任公司 Portable quick micro-droplet generator
KR20240005874A (en) * 2021-05-05 2024-01-12 살루스 디스커버리 엘엘씨 Stable interfacial systems and compositions
WO2025230964A1 (en) * 2024-04-30 2025-11-06 Bio-Rad Laboratories, Inc. Methods, systems, and apparatuses for generating and dispensing emulsion droplets

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110053798A1 (en) * 2009-09-02 2011-03-03 Quantalife, Inc. System for mixing fluids by coalescence of multiple emulsions
US20110229545A1 (en) * 2010-03-17 2011-09-22 President And Fellows Of Harvard College Melt emulsification
WO2011120024A1 (en) * 2010-03-25 2011-09-29 Quantalife, Inc. Droplet generation for droplet-based assays
WO2014039912A1 (en) * 2012-09-07 2014-03-13 Bio-Rad Laboratories, Inc. Compositions, systems and methods for droplet formation, spacing and detection

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5523162A (en) 1990-04-03 1996-06-04 Ppg Industries, Inc. Water repellent surface treatment for plastic and coated plastic substrates
JP5934657B2 (en) 2010-02-12 2016-06-15 レインダンス テクノロジーズ， インコーポレイテッド Digital specimen analysis
WO2015173658A2 (en) 2014-05-14 2015-11-19 Mark Davis Microfluidic devices that include channels that are slidable relative to each other and methods of use thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110053798A1 (en) * 2009-09-02 2011-03-03 Quantalife, Inc. System for mixing fluids by coalescence of multiple emulsions
US20110229545A1 (en) * 2010-03-17 2011-09-22 President And Fellows Of Harvard College Melt emulsification
WO2011120024A1 (en) * 2010-03-25 2011-09-29 Quantalife, Inc. Droplet generation for droplet-based assays
WO2014039912A1 (en) * 2012-09-07 2014-03-13 Bio-Rad Laboratories, Inc. Compositions, systems and methods for droplet formation, spacing and detection

Also Published As

Publication number Publication date
WO2018115978A2 (en) 2018-06-28

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