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WO2018033781A1 - Micro système de contrôle de glycémie et injection automatique d'insuline - Google Patents

Micro système de contrôle de glycémie et injection automatique d'insuline Download PDF

Info

Publication number
WO2018033781A1
WO2018033781A1 PCT/IB2016/055892 IB2016055892W WO2018033781A1 WO 2018033781 A1 WO2018033781 A1 WO 2018033781A1 IB 2016055892 W IB2016055892 W IB 2016055892W WO 2018033781 A1 WO2018033781 A1 WO 2018033781A1
Authority
WO
WIPO (PCT)
Prior art keywords
insulin
blood sugar
injection
micro system
control micro
Prior art date
Application number
PCT/IB2016/055892
Other languages
English (en)
Inventor
Nasim NAKHAIE
Original Assignee
Nakhaie Nasim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nakhaie Nasim filed Critical Nakhaie Nasim
Publication of WO2018033781A1 publication Critical patent/WO2018033781A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/82—Internal energy supply devices
    • A61M2205/8206—Internal energy supply devices battery-operated

Definitions

  • diabetes is a prevalent disease which is categorized in two different types:
  • Type 1 diabetes is an autoimmune disease and the main problem of people with Type 1 diabetes is the shortage of insulin.
  • Our purpose for designing this device is to monitor the blood sugar level of the patients as well as the injection of insulin with the least error rate.
  • the devices used for insulin delivery include U - 100 syringes.
  • One of the most common errors in this device is the precise draw up of insulin from the vial and the accurate way of injecting.
  • the other modern device used is known as Insulin prefilled pens one of the problems of which is not being used by the elderlies whose eyesight is weakened by diabetes.
  • the other form of insulin drug is the inhaled insulin which is not available in Iran.
  • This microsystem is the same size as an ordinary plaster and installing it on the body is as easy as a plaster. Sampling by sweat is conducted by the help of a thin touch kit; this invention has already been patented in the U.S with the patent number of US 2013/0053668.
  • the micro controller orders injecting insulin with the number of units required for the patient.
  • the insulin already embedded in the micro system is injected to the patient through the microneedle.
  • the possibility of delivering several accurate injections from this micro system is predicated and its number is variable. But the ideal number is six injections during two days. Afterwards, a new micro system must be installed on the body of the patient.
  • FIG. 1 is the schematic diagram of the microsystem
  • FIG. 2 is the diagram of the internal parts of central section
  • FIG. 3 is the bottom diagram of central section
  • FIG. 4 is the diagram of function of injector Detailed description of the drawings
  • a schematic diagram of the microsystem is seen which is composed of two sections: The external transparent section 1 which is as transparent as a plaster.
  • the blood sugar detection sensor by the sweat 2 is installed at a little distance from the external section.
  • the central section 3 is the one in which other pieces of the system is installed.
  • FIG. 2 the parts of central section are observed.
  • a micro battery 4 is installed to supply the energy required for the system and the micro controller 5 is responsible for the function of the system.
  • This function includes receiving the data of blood sugar detection sensor, data analysis, and giving injection order to the microneedles if required.
  • the other part includes microneedle 6 which is made of different subparts.
  • a mobile piece which has a hole on one side is on the chassis 10.
  • the other side of the mobile piece covers the hole of the chassis in the primary mode to avoid any kind of exchange through the needle.
  • the last piece is insulin storage 11 which is installed on the mobile piece.
  • the microcontroller activates electromagnet.
  • the magnet is activated, the mobile piece is attracted toward the magnet and therefore its hole matches on the hole of stable piece. Consequently, the passage of insulin entry into the body through the micro needle is opened and the content of insulin storage is evacuated.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

L'invention concerne un système ayant moins de taux d'erreur dans la quantité d'administration d'insuline, qui ne nécessite aucune compétence particulière pour l'utilisateur et mesure la glycémie périodiquement pendant la journée et la nuit. Le système maintient également le taux de glycémie dans une plage acceptable par injection de la quantité appropriée d'insuline. En concevant le dispositif constitué d'une micro-aiguille et d'une micropuce, l'insuline peut être injectée avec la précision la plus élevée et sans aucune douleur. En programmant la micropuce, plusieurs échantillonnages et mesures du taux de glycémie peuvent être effectués régulièrement pendant 24 heures et la probabilité de chute de glycémie grave et les problèmes critiques tels que le coma peuvent être réduits au minimum.
PCT/IB2016/055892 2016-08-13 2016-10-04 Micro système de contrôle de glycémie et injection automatique d'insuline WO2018033781A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IR13953006145 2016-08-13
IR139550140003006145 2016-08-13

Publications (1)

Publication Number Publication Date
WO2018033781A1 true WO2018033781A1 (fr) 2018-02-22

Family

ID=83267350

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2016/055892 WO2018033781A1 (fr) 2016-08-13 2016-10-04 Micro système de contrôle de glycémie et injection automatique d'insuline

Country Status (1)

Country Link
WO (1) WO2018033781A1 (fr)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2896407A1 (fr) * 2003-09-11 2005-03-24 Theranos, Inc. Dispositif medical permettant de surveiller un analyte et de distribuer des medicaments
WO2010045247A1 (fr) * 2008-10-14 2010-04-22 Vivomedical, Inc. Détecteurs de glucose dans la sueur et dispositifs de collecte pour une mesure du glucose
US20120316503A1 (en) * 2011-06-10 2012-12-13 Russell Frederick Ross Transdermal Device Containing Microneedles
WO2015119906A1 (fr) * 2014-02-05 2015-08-13 Amgen Inc. Système d'administration de médicament doté d'un générateur de champ électromagnétique

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2896407A1 (fr) * 2003-09-11 2005-03-24 Theranos, Inc. Dispositif medical permettant de surveiller un analyte et de distribuer des medicaments
WO2010045247A1 (fr) * 2008-10-14 2010-04-22 Vivomedical, Inc. Détecteurs de glucose dans la sueur et dispositifs de collecte pour une mesure du glucose
US20120316503A1 (en) * 2011-06-10 2012-12-13 Russell Frederick Ross Transdermal Device Containing Microneedles
WO2015119906A1 (fr) * 2014-02-05 2015-08-13 Amgen Inc. Système d'administration de médicament doté d'un générateur de champ électromagnétique

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
KHANNA P ET AL.: "Microneedle-Based Automated Therapy for Diabetes Mellitus", JOURNAL OF DIABETES SCIENCE AND TECHNOLOGY, vol. 2, no. 6, 2008, pages 1122 - 1129, XP055466437 *

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