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WO2015018471A1 - Pni (psychoneuroimmunium) lobbyist cell protection - Google Patents

Pni (psychoneuroimmunium) lobbyist cell protection Download PDF

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Publication number
WO2015018471A1
WO2015018471A1 PCT/EP2014/001769 EP2014001769W WO2015018471A1 WO 2015018471 A1 WO2015018471 A1 WO 2015018471A1 EP 2014001769 W EP2014001769 W EP 2014001769W WO 2015018471 A1 WO2015018471 A1 WO 2015018471A1
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Prior art keywords
root
pni
psychoneuroimmunium
herb
vitamin
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PCT/EP2014/001769
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German (de)
French (fr)
Inventor
Ernst Fekete
Karin Hübner
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Ernst Fekete
Karin Hübner
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Publication of WO2015018471A1 publication Critical patent/WO2015018471A1/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07Retinol compounds, e.g. vitamin A
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/417Imidazole-alkylamines, e.g. histamine, phentolamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4415Pyridoxine, i.e. Vitamin B6
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A61K31/51Thiamines, e.g. vitamin B1
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135Compounds containing heavy metals
    • A61K31/714Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/26Iron; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/42Phosphorus; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Definitions

  • the invention relates to the use of pure "PNI", cell protection of a physiologically acceptable purely natural active ingredient, a herbal preparation for the manufacture of a medicament for the treatment of internal and external cancer and non-inflammatory rheumatic diseases and diabetes.
  • the medical device can be used as:
  • immune regulation is activated via the stress axis
  • the present invention is a synergistic combination of exclusively natural active ingredients for supporting and dynamizing the "stress axis" from the microorganisms of the intestine to the adrenal cortex to the pituitary gland.
  • stress axis describes the communication between the intestinal bacterial system and the brain via nerve cells of the intestinal wall (enteric nervous system), biochemical messengers, the adrenal cortex, the blood and neuronal bandages.
  • the adaptive antigen-presenting cells of the white blood cells (T and B lymphocytes, monocytes, macrophages) play an important role as mediators, as well as the dendritic cells, whose extensions can be found on the skin, mucosa and lymphatic tissue.
  • T and B lymphocytes, monocytes, macrophages play an important role as mediators, as well as the dendritic cells, whose extensions can be found on the skin, mucosa and lymphatic tissue.
  • it deals with the recording and processing of externally recorded, on the other organic and psychic signals; the communication of organs and regulatory circuits and, above all, meaningful and efficient countermeasures of a body that has to deal with infections, parasites and / or cancerous tumors.
  • the present invention of Psychoneuroimmunium is surpassed by any drug, no vitamin and no single therapeutic measure that allows even approximately affecting the learning success towards intestinal and stomach bacteria, immune system and brain.
  • the vibrational and informative power of the microorganisms of the microorganisms play an equally important role here Intestine (which is absorbed and transmitted by the enteric nervous system) as well as the energy transfer via the so-called “stress axis" from the intestinal wall via the organs to the adrenals, from there to the brain.
  • the "PNI” thus acts as a kind of control center for the control and control of the cell activity.Not forget the effect of the "PNI” the functionality of the blood, whose information, cleaning and nutrient power depends on many factors and also about it can be influenced very well by vital substances.
  • the ability of the organism with its immune system to defend against the establishment of growing cancer cell colonies largely depends on the functioning of the circuits just mentioned. Of particular note is the ability of the brain to activate, direct and control natural killer cells, T and B lymphocytes, monocytes and macrophages via nerve signals.
  • the "PNI" can supplement one of the biggest bottlenecks in medicine.
  • the Healing traditions of Medicine, TCM and INDM have been designed to support the overall organic learning and counter-regulation of a living system, such as human beings (or animals, for example), who are in stress and seeking ways, to reorganize and adjust at both the organ and information levels in order to create longer term wellbeing.
  • the term is apt when it is said that "PNI" has identified a lobbyist that reunites the fully available mechanisms and regulatory circuits of the autonomic and central nervous systems.
  • PNI palindromic nucleus
  • Processes in living systems can reflect bodily processes and mental reactions the physical. They can be replaced by alternating or running at the same time, which promotes irritation with concomitant weakening of the immune system. This has a massive impact on the desired healing success. It is precisely the balance and balance between the physicality and the mind of the human being that is to be regulated by "PNI" and, through its mode of action, regain the upper hand in order to restore order in the human body for recovery.
  • the present invention of "PNI” breaks this cycle and regulates it, on the other hand parasites, infections and tumor cells are uncovered by the plant agents used in the "PNI” by the body's own energetic charging processes, which can only be proven in the defective cell What strengthens the present medical device "PNI” in its mode of action.As known, cancer patients are not feverish, are included in the "PNI” agents that can retrieve this program mentioned above.
  • the artificial overheating causes a number of other mechanisms, each directly or indirectly harmful to the tumor tissue.
  • the capillary vessels in the tumor tissue usually have no muscle layer and are therefore not able to expand in the fever-like overheating, in contrast to the microvessels in adjacent healthy tissue.
  • the heat generated by the energetic program of the "PNI” remains due to the resulting reduced blood flow substantially in the tumor tissue and thus causes a selective increase in tumor temperature.
  • This caused by the "PNI” in the natural way "heat trap” thus leads to an oxygen deficiency and a nutrient depletion in the tumor, which leads to a disruption of important metabolic processes in cell division and Zellerigen.
  • Acidosis (acid) of carcinogenic cells
  • Acidosis of carcinogenic cells is a metabolic rate increased by the formation of heat. These and the resulting oxygen deficit (hypoxia) force the tumor cell to anaerobic energy production. The tumor cell now gains its energy, e.g. by converting the sugar from the intracellular space. This transformation produces lactate and thus increasingly an acidic cell milieu, which leads to a malfunction in the cell and due to the simultaneously disturbed repair mechanisms to the death of the diseased cells (apoptosis) by acidosis.
  • the fever-like situation causes a constant damage of the lipid bilayer of the tumor cells and thus an altered lipid-protein interaction. This can result in denaturing of the cellular proteins and significantly disrupt the cell's ability to divide.
  • the medical device psychoneuroimmunium can be said to deprive the tumor cell of any opportunity to obtain nutrients or tap into such sources, and the tumor is starving, noting that cancer avoids a starving system and thus eliminates itself.
  • PNI Quality of life of humans in their worst crisis
  • the active substance Psychoneuroimmunium contains the following ingredients: Stock List Herbs:
  • the herb and root powder mixture also contains, in purely natural form, further below-mentioned modes of action, which are coordinated with one another according to their purpose: Angelica root, Stinging nettle, Valerian herb, Ceylon green OP, Chelidonium, Carduus marianus, Eberraut herb, Echtas lab herb, Fennel, Ginko, Goldenrod herb, Cloves, Elderflower, Oat green, Ginger, Lapacho bark, Calamus root, Nasturtium, Corn hair, Lab herb, Milk thistle herb, Melissa leaves, Mistletoe , Horseradish root, passion flower, Pommera peel bitter, butterbur, yarrow, licorice root, rose root, rose petals, iris root, pansy blue-flowering, taiga root, devil's claw, juniper
  • the other active ingredients are: bearded helmet herb, Oldenlandiakraut, Chinese cinnamon bark / cassia, red radish sage root, citrus root, chines.

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Abstract

The invention relates to the use of pure "PNI", cell protection of a physiologically acceptable purely natural active ingredient, a plant preparation for producing a drug for treating cellular and cancer diseases for internal and external use. This active ingredient "PNI" is a synergistic combination of exclusively natural active ingredients for supporting and dynamizing the stress axis, wherein the active ingredients cause communication between the system of the intestinal bacteria and the brain via nerve cells of the intestinal wall (enteric nervous system), biochemical messengers, the adrenal cortex, the blood, and neural connections to function in order to achieve the healing effect.

Description

Lobbyist-Zellschutz PNI (Psychoneuroimmunium)  Lobbyist Cell Protection PNI (Psychoneuroimmunium)
Bezeichnung: Description:
Verwendung des Wirkstoffes „PNI" Psychoneuroimmunium zur Behandlung von Zellerkrankungen, Leukämischen Erkrankungen, Leberkrebs mit Metastasierung, Diabetes, rheumatischen Erkrankungen sowie Gelenkschmerzen.  Use of the active substance "PNI" Psychoneuroimmunium for the treatment of cell diseases, leukemic diseases, liver cancer with metastasis, diabetes, rheumatic diseases and joint pain.
Beschreibung description
Die Erfindung betrifft die Verwendung von reinem „PNI", Zellschutz eines physiologisch annehmbaren rein natürlichen Wirkstoffes, einer pflanzlichen Zubereitung zur Herstellung eines Arzneimittels zur Behandlung von Krebserkrankungen zur inneren und äußerlichen Anwendung sowie nicht entzündlich rheumatischer Erkrankungen und Diabetes. Es handelt sich um ein Medizinprodukt. The invention relates to the use of pure "PNI", cell protection of a physiologically acceptable purely natural active ingredient, a herbal preparation for the manufacture of a medicament for the treatment of internal and external cancer and non-inflammatory rheumatic diseases and diabetes.
Das Medizinprodukt ist einsetzbar als: The medical device can be used as:
Integrative Medizin - begleitend zu Chemo-Bestrahlungen und anderen medikamentösen und operativen Behandlungsmethoden, Integrative medicine - concomitant with chemo-radiation and other medical and surgical treatment methods,
Adjuvante Therapie, Adjuvant therapy,
Monotherapie, Monotherapy
selbständige Therapie nach erfolglosen Vorbehandlungen. independent therapy after unsuccessful pre-treatment.
Stand der Technik State of the art
Es gibt eine Reihe von Medizinprodukten, die jedoch in ihrer Reichweite nicht der vorliegenden Erfindung nahekommen. Hier handelt es sich um eine Kombination aus natürlichen und pflanzlichen Produkten, die so nicht bekannt sind und daher nicht dem Stand der Technik entsprechen, sondern diesen erhöhen. Das vorliegende Medizin produkt Psychoneuroimmunium bewirkt There are a number of medical devices, but they are not within the scope of the present invention. This is a combination of natural and herbal products that are not known and therefore do not conform to the state of the art but increase it. The present medicine product Psychoneuroimmunium causes
1. fieberähnliche Reaktionen und zerstört Tumore und schadhafte Zellen oder hungert diese aus, 1. Fever-like reactions and destroy or starve tumors and damaged cells,
2. Immunregulation wird über die Stressachse aktiviert,  2. immune regulation is activated via the stress axis,
3. Organaufbau greift positiv in die DNA ein.  3. Organ structure engages positively in the DNA.
Bei der vorliegenden Erfindung handelt es sich um eine synergetische Kombination von ausschließlich natürlichen Wirkstoffen zur Unterstützung und Dynamisierung der „Stress-Achse" von den Mikroorganismen des Darmes über die Nebennierenrinde bis zur Hypophyse. The present invention is a synergistic combination of exclusively natural active ingredients for supporting and dynamizing the "stress axis" from the microorganisms of the intestine to the adrenal cortex to the pituitary gland.
Psychoneuroimmunium wirkt nach folgendem Prinzip: Psychoneuroimmunium acts according to the following principle:
Der Begriff„Stress-Achse" umschreibt die Kommunikation zwischen dem System der Darmbakterien und dem Gehirn über Nervenzellen der Darmwand (enterisches Nervensystem), biochemische Botenstoffe, die Nebennierenrinde, das Blut und über Neuronenverbände. Eine wichtige Mittlerfunktion spielen dabei einerseits die lernfähigen antigenpräsen- tierenden Zellen der weißen Blutkörperchen (T- und B-Lymphozyten, Monozyten, Makrophagen), sowie die dendritischen Zellen, deren Ausläufer auf Haut, Schleimhaut und lymphatischem Gewebe zu finden sind. Es dreht sich also einerseits um Aufnahme und Verarbeitung von extern aufgenommenen, andererseits organischen und psychischen Signalen; um die Kommunikation von Organen und Regulationskreisen und vor allem um sinnvolle und effiziente Gegenmaßnahmen eines Körpers, der sich mit Infekten, Parasiten und/oder Krebsgeschwülsten auseinandersetzen muss. The term "stress axis" describes the communication between the intestinal bacterial system and the brain via nerve cells of the intestinal wall (enteric nervous system), biochemical messengers, the adrenal cortex, the blood and neuronal bandages. On the one hand, the adaptive antigen-presenting cells of the white blood cells (T and B lymphocytes, monocytes, macrophages) play an important role as mediators, as well as the dendritic cells, whose extensions can be found on the skin, mucosa and lymphatic tissue. On the one hand, it deals with the recording and processing of externally recorded, on the other organic and psychic signals; the communication of organs and regulatory circuits and, above all, meaningful and efficient countermeasures of a body that has to deal with infections, parasites and / or cancerous tumors.
Die vorliegende Erfindung des Psychoneuroimmunium wird von keinem Medikament, keinem Vitamin und keiner einzelnen therapeutischen Maßnahme übertroffen, die auch nur annähernd eine Beeinflussung des Lernerfolges in Richtung Darm- und Magenbakterien, Immunsystem und Gehirn ermöglicht.  The present invention of Psychoneuroimmunium is surpassed by any drug, no vitamin and no single therapeutic measure that allows even approximately affecting the learning success towards intestinal and stomach bacteria, immune system and brain.
Die vorliegende Erfindung des „PNI" fördert die Aktivität und Organisation aller Körperzellen und wird einerseits von bio-elektromagnetischen (= morpho- genetischen) Feldern koordiniert, andererseits durch kohärente Lichtimpulse. Eine gleich bedeutende Rolle spielen hierbei sowohl die Schwingungs- und Informationskraft der Mikroorganismen des Darmes (die vom enterischen Nervensystem aufgenommen und übertragen wird) als auch die Energieweitergabe über die sogenannte „Stress-Achse" von der Darmwand über die Organe zur Nebenniere, von dort aus zum Gehirn. The present invention of the "PNI" promotes the activity and organization of all body cells and is coordinated on the one hand by bio-electromagnetic (= morpho-genetic) fields, on the other hand by coherent light pulses.The vibrational and informative power of the microorganisms of the microorganisms play an equally important role here Intestine (which is absorbed and transmitted by the enteric nervous system) as well as the energy transfer via the so-called "stress axis" from the intestinal wall via the organs to the adrenals, from there to the brain.
Das„PNI" wirkt somit als eine Art Schaltzentrale für die Lenkung und Kontrolle der Zellaktivität. Nicht vergessen werden darf bei dieser Wirkung des „PNI" die Funktionalität des Blutes, dessen Informations-, Reinigungs- und Nährkraft von vielen Faktoren abhängig ist und auch darüber sehr gut durch Vitalstoffe beeinflusst werden kann. The "PNI" thus acts as a kind of control center for the control and control of the cell activity.Not forget the effect of the "PNI" the functionality of the blood, whose information, cleaning and nutrient power depends on many factors and also about it can be influenced very well by vital substances.
Die Fähigkeit des Organismus mit seinem Immunsystem, sich gegen das Festsetzen von wachsenden Krebszell-Kolonien zu wehren, ist weitgehend abhängig vom Funktionieren der eben genannten Schaltkreise. Hervorzuheben ist hierbei die Fähigkeit des Gehirns, über Nervensignale die natürlichen Killerzellen, T- und B- Lymphozyten, Monozyten und Makrophagen zu aktivieren, zu lenken und zu kontrollieren. Hier kann die„PNI" einen der größten Engpässe der Medizin ergänzen. The ability of the organism with its immune system to defend against the establishment of growing cancer cell colonies largely depends on the functioning of the circuits just mentioned. Of particular note is the ability of the brain to activate, direct and control natural killer cells, T and B lymphocytes, monocytes and macrophages via nerve signals. Here, the "PNI" can supplement one of the biggest bottlenecks in medicine.
Soweit bekannt, ist im pharmakologischen Bereich bisher fast ausnahmslos an Einzelsubstanzen geforscht worden, es ist bisher nicht gelungen, Substanzen und Medikamente zu entwickeln, die das Gehirn bei seiner Lenkungstätigkeit der Immunzellen zur Eliminierung von Krebszell-Verbänden unterstützen. As far as is known, in the pharmacological field has so far been investigated almost exclusively on individual substances, it has not been able to develop substances and drugs that support the brain in its steering activity of immune cells to eliminate cancer cell associations.
Es liegt die Überzeugung zugrunde, dass nur alle genannten Faktoren miteinander die Apoptose in erkrankten lebenden Systemen wieder aktiveren können und somit für eine positive Umstimmung des lebenden Systems den notwendigen Zelltod einleiten. Genau hier an diesem Punkt setzt vorliegende vorteilhafte Erfindung des Psychoneuroimmuniums (PNI) an, die synergistische Kombination rein energetischinformierender Substanzen, gekoppelt an das Verständnis westlicher Medizin und asiatischer Medizinsysteme. It is based on the conviction that only all the factors mentioned above can reactivate apoptosis in diseased living systems and thus initiate the necessary cell death for a positive change of the living system. Right here at this point, present beneficial invention of Psychoneuroimmuniums (PNI), the synergistic combination of purely energetic-informing substances, coupled with the understanding of Western medicine and Asian medical systems.
Die Heilertraditionen der Medizin, der TCM und der INDM, wurden auf das Ziel hin konzipiert, die gesamtorganische Lern- und Gegenregulation eines lebenden Systems wie der Mensch (oder beispielsweise auch bei Tieren) zu unterstützen, das sich im Stress befindet und nach Wegen sucht, sich auf Organ- und auch auf Informationsebene neu zu organisieren und zu justieren, damit ein längerfristiges Wohlergehen entsteht. The Healing Traditions of Medicine, TCM and INDM, have been designed to support the overall organic learning and counter-regulation of a living system, such as human beings (or animals, for example), who are in stress and seeking ways, to reorganize and adjust at both the organ and information levels in order to create longer term wellbeing.
Bei vorliegender vorteilhafter Erfindung ergibt sich die Bezeichnung als treffend, wenn gesagt wird, dass mit„PNI" eine Lobbyist identifiziert wurde, der die komplett zur Verfügung stehenden Mechanismen und Regulationsschaltkreise des vegetativen und des zentralen Nervensystems wieder vereint. In dem Applizieren des„PNI" in den Musculus gluteus maximus (größter Gesäßmuskel) ist die Ordnung und die Zuordnung in alle menschlichen Regulationssysteme zu sehen. In the present invention, the term is apt when it is said that "PNI" has identified a lobbyist that reunites the fully available mechanisms and regulatory circuits of the autonomic and central nervous systems. in the gluteus maximus muscle (largest gluteal muscle) the order and the assignment in all human regulatory systems can be seen.
Vorgänge in lebenden Systemen, gerade in Phasen einer Erkrankung, können körperliche Prozesse widerspiegeln und psychische Reaktionen die körperlichen. Sie können ersetzt werden, indem sie sich abwechseln oder gleichzeitig ablaufen, was Irritationen bei gleichzeitiger Schwächung des Immunsystems begünstigt. Dies wirkt sich massiv gegen die gewünschten Heilerfolge aus. Gerade das Gleichgewicht und die Balance zwischen Körperlichkeit und Verstand des Menschen soll durch „PNI" reguliert werden und durch seine Wirkungsweise die Oberhand zurück erlangen, um Ordnung im menschlichen Körper zur Gesundung zu schaffen. Processes in living systems, especially in phases of a disease, can reflect bodily processes and mental reactions the physical. They can be replaced by alternating or running at the same time, which promotes irritation with concomitant weakening of the immune system. This has a massive impact on the desired healing success. It is precisely the balance and balance between the physicality and the mind of the human being that is to be regulated by "PNI" and, through its mode of action, regain the upper hand in order to restore order in the human body for recovery.
Vorliegende Erfindung des„PNI" durchbricht zum einen diesen Kreislauf und reguliert ihn. Zum anderen werden Parasiten, Infekte und Tumorzellen durch die im Rahmen des „PNI" eingesetzten pflanzlichen Mittel durch körpereigene energetische Aufladungsprozesse, die nachweislich nur in der schadhaften Zelle entstehen können, enttarnt, was das vorliegende Medizinprodukt„PNI" in seiner Wirkungsweise noch verstärkt. Da bekannter Weise Krebspatientinnen und -patienten nicht fiebern, sind in dem„PNI" Wirkstoffe enthalten, die dieses vorgenannte Programm abrufen können. On the one hand, the present invention of "PNI" breaks this cycle and regulates it, on the other hand parasites, infections and tumor cells are uncovered by the plant agents used in the "PNI" by the body's own energetic charging processes, which can only be proven in the defective cell What strengthens the present medical device "PNI" in its mode of action.As known, cancer patients are not feverish, are included in the "PNI" agents that can retrieve this program mentioned above.
Neben den durch fieberähnliche Reaktionen durch „PNI" hervorgerufenen systemischen Wirkungen, wie zum Beispiel die Aktivierung des Immunsystems und die Schmerzlinderung, bedingt die künstliche Überhitzung eine Reihe weiterer Mechanismen, die jeweils direkt oder indirekt schädigend auf das Tumorgewebe einwirken. In addition to the systemic effects caused by fever-like reactions caused by "PNI", such as the activation of the immune system and pain relief, the artificial overheating causes a number of other mechanisms, each directly or indirectly harmful to the tumor tissue.
Im Folgenden sind die einzelnen Mechanismen und ihre Auswirkungen auf den Tumor im Zusammenwirken mit der vorteilhaften Erfindung des„PNI" beschrieben. Die Minderdurchblutung im Tumor durch Gefäßveränderung: The following describes the individual mechanisms and their effects on the tumor in cooperation with the advantageous invention of the "PNI". The reduced circulation in the tumor due to vascular change:
Neben einem insuffizienten Wandaufbau besitzen die kapillaren Gefäße im Tumorgewebe in der Regel keinerlei Muskelschicht und sind somit auch im Gegensatz zu den Mikrogefäßen im angrenzenden gesunden Gewebe nicht in der Lage, sich bei der fieberähnlichen Überhitzung auszudehnen. Die stärkere Durchblutung des den Tumor umgebenden gesunden Gewebes führt zu einer reaktiven Minderdurchblutung des Tumorgewebes (Steelphänomen = Minderdurchblutung). Die durch das energetische Programm des „PNI" erzeugte Wärme verbleibt aufgrund der resultierenden Minderdurchblutung im Wesentlichen im Tumorgewebe und bedingt somit eine selektive Erhöhung der Tumortemperatur. Diese durch das „PNI" auf natürlichem Wege hervorgerufene„Hitzefalle" führt somit zu einem Sauerstoffmangel und einer Nährstoffverarmung im Tumor, was zu einer Störung wichtiger Stoffwechselprozesse bei der Zellteilung und der Zellerhaltung führt. In addition to an insufficient wall structure, the capillary vessels in the tumor tissue usually have no muscle layer and are therefore not able to expand in the fever-like overheating, in contrast to the microvessels in adjacent healthy tissue. The increased circulation of the healthy tissue surrounding the tumor leads to a reduced reactive blood flow to the tumor tissue (steel phenomenon = reduced blood flow). The heat generated by the energetic program of the "PNI" remains due to the resulting reduced blood flow substantially in the tumor tissue and thus causes a selective increase in tumor temperature. This caused by the "PNI" in the natural way "heat trap" thus leads to an oxygen deficiency and a nutrient depletion in the tumor, which leads to a disruption of important metabolic processes in cell division and Zellerhaltung.
Azidose (Säure) der karzinogenen Zellen: Acidosis (acid) of carcinogenic cells:
Azidose der karzinogenen Zellen ist eine durch die Hitzebildung gesteigerte Stoffwechselgeschwindigkeit. Diese und das entstandene Sauerstoffdefizit (Hypoxie) zwingen die Tumorzelle zu einer anaeroben Energiegewinnung. Die Tumorzelle gewinnt ihre Energie nun z.B. durch die Umwandlung des Zuckers aus dem intrazellulären Raum. Durch diese Umwandlung entsteht Laktat und somit vermehrt ein saures Zellmilieu, was zu einer Funktionsstörung in der Zelle und aufgrund der gleichzeitig gestörten Reparaturmechanismen zum Absterben der krankhaften Zellen (Apoptose) durch Azidose führt. Acidosis of carcinogenic cells is a metabolic rate increased by the formation of heat. These and the resulting oxygen deficit (hypoxia) force the tumor cell to anaerobic energy production. The tumor cell now gains its energy, e.g. by converting the sugar from the intracellular space. This transformation produces lactate and thus increasingly an acidic cell milieu, which leads to a malfunction in the cell and due to the simultaneously disturbed repair mechanisms to the death of the diseased cells (apoptosis) by acidosis.
ATP (universeller Energieträger in lebenden Systemen)-Verarmung im Tumorgewebe: ATP (universal energy source in living systems) depletion in tumor tissue:
Durch die gesteigerte Stoffwechselgeschwindigkeit durch das Verabreichen von„PNI" und das Fehlen von Sauerstoff und Nährstoffen im Tumorgewebe werden die zellulären ATP-Speicher beträchtlich entleert. Dies führt ebenfalls zu einer erhöhten Zellstörung. Increased metabolic rate through the administration of "PNI" and the lack of oxygen and nutrients in the tumor tissue significantly deplete the cellular ATP stores, which also leads to increased cell disruption.
Veränderung der Zellmembran von Tumorzellen: Alteration of the cell membrane of tumor cells:
Die fieberähnliche Situation bewirkt ein stetige Schädigung der Lipid- Doppelschicht der Tumorzellen und somit auch eine veränderte Lipid-Protein- Interaktion. Dies kann in der Folge zum Denaturieren der zellulären Proteine führen und die Teilungsfähigkeit der Zelle wesentlich stören. The fever-like situation causes a constant damage of the lipid bilayer of the tumor cells and thus an altered lipid-protein interaction. This can result in denaturing of the cellular proteins and significantly disrupt the cell's ability to divide.
Zerstörung der Tumorzellen durch thermo-dynamischen Druck auf die Zellwände: Aufgrund des Temperaturanstieges verändern sich die transmembranen Proteine und somit in Folge auch die Membranpermeabilität und die Membrankapazität. Dies wiederum führt zu einer Änderung der Kalium-, Kalzium- und Natrium-Ionen- Verteilung in der Tumorzelle. Durch die Ionen (Wasser)-Wanderung in den intrazellulären Raum erhöht sich während der Therapie der Wasserdruck im Zytoplasma und verursacht somit einen energetisch hervorgerufenen thermo-dynamischen Druck auf die Zellwand. Dies führt zu einer weiteren Destabilisierung der Tumor-Zellmembran. Destruction of the tumor cells by thermo-dynamic pressure on the cell walls: Due to the increase in temperature, the transmembrane proteins change, and consequently also the membrane permeability and the membrane capacity. This in turn leads to a change in the potassium, calcium and sodium ion distribution in the tumor cell. The ion (water) migration into the intracellular space increases the pressure of the water in the cytoplasm during therapy and thus causes an energetically induced thermo-dynamic pressure on the cell wall. This leads to a further destabilization of the tumor cell membrane.
Direkte Tumornekrose: Direct tumor necrosis:
Bei absoluten Tumortemperaturen, hervorgerufen durch energetische Übertragungs-prozesse, die sich innerhalb schadhafter Zellen von ca. 40 - 42 °C bilden können, werden die in der Regel hitzeempfindlicheren Tumorzellen auch direkt letal (tödlich) geschädigt. At absolute tumor temperatures, caused by energetic transfer processes, which can form within defective cells of about 40 - 42 ° C, the usually more heat-sensitive tumor cells are also directly lethal (fatal) damaged.
Abnahme der DNA-Replikationsgeschwindigkeit der Tumorzellen: Decrease in the DNA replication rate of the tumor cells:
Durch erhöhte Temperaturen kann die DNA-Replikation der Tumorzellen verlangsamt oder sogar völlig gestoppt werden und im günstigsten Fall die Krankheit besiegen. Ein Abstürzen„des lebenden Systems (Zellen etc.)" ist nicht möglich, da das gesunde körpereigene System durch die von Beginn an betriebenen Organfunktionsaufbauten und Stabilisierungen durch„PNI" intakt bleiben. Increased temperatures can slow down or even completely stop the DNA replication of the tumor cells and, in the best case, defeat the disease. Crashes of "the living system (cells, etc.)" is not possible because the healthy endogenous system remains intact due to the initial organ function build-up and stabilization by "PNI".
Zusammenfassend kann abschließend zu dem Medizinprodukt Psychoneuroimmunium („PNI") gesagt werden, dass dieses den Tumor-Zellen alle Möglichkeiten nimmt, sich Nährstoffe zu besorgen oder solche Quellen anzuzapfen. Der Tumor wird ausgehungert, wobei darauf hinzuweisen ist, dass Krebs ein hungerndes System meidet und somit sich selbst eliminiert. In conclusion, the medical device psychoneuroimmunium ("PNI") can be said to deprive the tumor cell of any opportunity to obtain nutrients or tap into such sources, and the tumor is starving, noting that cancer avoids a starving system and thus eliminates itself.
Die Lebensqualität des Menschen in seiner wohl schwersten Krise kann durch „PNI" deutlich verbessert werden, was als erster Schritt in Richtung Heilchance zu betrachten ist. The quality of life of humans in their worst crisis can be significantly improved by "PNI", which is to be considered as a first step towards healing.
Alle uns bekannten Heilungen, angefangen von dem Phänomen der Spontanreaktion bis hin zur gezielten Eliminierung schadhafter Zellen durch natürliche Wirkstoffe, sind in dem Wirkstoff„PNI" sorgfältig bedacht worden. All healings known to us, ranging from the phenomenon of spontaneous reaction to the targeted elimination of defective cells by natural active ingredients, have been carefully considered in the drug "PNI".
Der Wirkstoff Psychoneuroimmunium („PNI") enthält folgende Ingredienzien: Bestandsliste-Kräuter: The active substance Psychoneuroimmunium ("PNI") contains the following ingredients: Stock List Herbs:
Das Kraut- und Wurzelpulvergemisch beinhaltet neben Ameisensäure, Kieselsäure, Gallussäure, Gerbsäure, Calcium, Eisen, Histamin, Kalium, Magnesium, Natrium, Phosphor, Skretin und Vitamin A in rein natürlicher Form noch weitere nachstehende Wirkungsrichtungen, die ihrem Zweck gemäß aufeinander abgestimmt sind: Angelikawurzel, Brennessel, Baldriankraut, Ceylon grün OP, Chelidonium, Carduus marianus, Eberrautenkraut, Echtas Labkraut, Fenchel, Ginko, Goldrutenkraut, Gewürznelken, Holunderblüten, Hafertee grün, Ingwer, Lapachorinde, Kalmuswurzel, Kapuzinerkressenkraut, Maisbarthaar, Labkraut, Mariendistelkraut, Melissenblätter, Mistelkraut, Meerrettichwurzel, Passionsblume, Pommeranzschalen bitter, Pestwurz, Schafgarbe, Süßholzwurzel, Rosenwurz, Rosenblüten, Schwertlilienwurzel, Stiefmütterchen blaublühend, Taigawurzel, Teufelskralle, Wachholderbeeren, Weidenrinde, Weyhrauch, Wildhimbeerfrüchte chine., Weintraubenkerne, Wermut, Zypressenspitzen sowie die Vitamine A, B 1 , B 6, B 12. In addition to formic acid, silicic acid, gallic acid, tannic acid, calcium, iron, histamine, potassium, magnesium, sodium, phosphorus, skretin and vitamin A, the herb and root powder mixture also contains, in purely natural form, further below-mentioned modes of action, which are coordinated with one another according to their purpose: Angelica root, Stinging nettle, Valerian herb, Ceylon green OP, Chelidonium, Carduus marianus, Eberraut herb, Echtas lab herb, Fennel, Ginko, Goldenrod herb, Cloves, Elderflower, Oat green, Ginger, Lapacho bark, Calamus root, Nasturtium, Corn hair, Lab herb, Milk thistle herb, Melissa leaves, Mistletoe , Horseradish root, passion flower, Pommera peel bitter, butterbur, yarrow, licorice root, rose root, rose petals, iris root, pansy blue-flowering, taiga root, devil's claw, juniper berries, willow bark, wey hay, wild raspberry fruits chine, grape seeds, wormwood, cypress tips and vitamins A, B 1, B 6, B 12.
Die weiteren Wirkstoffe sind: bärtiges Helmkraut, Oldenlandiakraut, chinesische Zimtrinde/Cassia, Rotwurzsalbeiwurzel, Zitwerwurzel, chines. Engelwurz, Fieberstrauchwurzel, Rohrkolbenpollen, Windenglockenwurzel, koreanische Ginsengwurzel, Malayische Teefrucht/Harzklee, Traganthwurzel (Astragalus), chin. Odermennigkraut (pilosa), Kiefernschwamm mit Wurzel, Hasenohrwurzel, Goldfadenwurzelstock, Braunwurzel/Ningpo, Traubensilberkerzenwurzel, Piment (Nelkenpfeffer), Rhabarberwurzel/Rhapontik. The other active ingredients are: bearded helmet herb, Oldenlandiakraut, Chinese cinnamon bark / cassia, red radish sage root, citrus root, chines. Angelica root, Fever shrub root, Cattail pollen, Wind bell root, Korean ginseng root, Malayan tea clover, Tragacanth root (Astragalus), Chinese oxwort (pilosa), pine sponge with root, hare ear root, Goldfadenwurzelstock, Braunwurzel / Ningpo, black cohosh root, allspice (peppercorn), Rhubarb root / Rhapontik ,

Claims

Patentansprüche claims
1. 1.
Die Erfingung„PNI" (Psychoneuroimmunium) betrifft die Verwendung von reinem„PNI", Zellschutz eines physiologisch annehmbaren rein natürlichen Wirkstoffs, einer pflanzlichen Zubereitung zur Herstellung eines Arzneimittels zur Behandlung von Zellerkrankungen, Leukämischen Erkrankungen, Leberkrebs mit Metastasierung, Diabetes, rheumatischen Erkrankungen sowie Gelenkschmerzen und ist dadurch gekennzeichnet, dass der ,,ΡΝΓ'- Zellschutz aus einer pflanzlichen Zubereitung besteht.  The invention "PNI" (Psychoneuroimmunium) relates to the use of pure "PNI", cell protection of a physiologically acceptable all natural active ingredient, a herbal preparation for the manufacture of a medicament for the treatment of cell diseases, leukemic diseases, liver cancer with metastasis, diabetes, rheumatic diseases and joint pain and is characterized in that the ΡΝΓ'-cell protection consists of a herbal preparation.
2. Second
Psychoneuroimmunium„PNI" nach Anspruch 1 , dadurch gekennzeichnet, dass der„PNI"- Zellschutz aus nachfolgenden Inhaltsstoffen besteht:  Psychoneuroimmunium "PNI" according to claim 1, characterized in that the "PNI" cell protection consists of the following ingredients:
Ameisensäure, formic acid,
Kieselsäure,  silica,
Gallussäure,  Gallic acid,
Gerbsäure,  tannic acid,
Calcium,  calcium,
Eisen,  Iron,
Histamin,  Histamine,
Kalium,  Potassium,
Magnesium,  Magnesium,
Natrium,  Sodium,
Phosphor,  Phosphorus,
Skretin  Skretin
Vitamin A  Vitamin A
jeweils in der Menge von 1/1.000 mg / 1/1.000 ml bis 1.000 g / 1.000 ml each in the amount of 1 / 1,000 mg / 1 / 1,000 ml to 1,000 g / 1,000 ml
3. Third
Psychoneuroimmunium„PNI" nach Anspruch 1 und 2, dadurch gekennzeichnet, dass das Psychoneuroimmunium„PNI" folgende weitere Inhaltsstoffe hat:  Psychoneuroimmunium "PNI" according to claim 1 and 2, characterized in that the Psychoneuroimmunium "PNI" has the following additional ingredients:
Angelikawurzel, Angelica root,
Brennessel, Nettle,
Baldriankraut, Valerian herb
Ceylon grün OP, Ceylon green OP,
Chelidonium, Chelidonium,
Carduus marianus, Carduus marianus,
Eberrautenkraut, Eberrautenkraut,
Echtas Labkraut, Fenchel, Echta's lab herb, Fennel,
Ginko, Ginko,
Goldrutenkraut,  Goldenrod,
Gewürznelken, Cloves,
Holunderblüten, Elderflower,
Hafertee grün, Oat tea green,
Ingwer, Ginger,
Lapachorinde,  lapacho,
Kalmuswurzel,  calamus root,
Kapuzinerkressenkraut,  Nasturtium herb,
Maisbarthaar,  Corn beard,
Labkraut,  bedstraw,
Mariendistelkraut,  Milk thistle herb
Melissenblätter,  Lemon balm leaves,
Mistelkraut,  Mistletoe,
Meerrettichwurzel,  Horseradish root,
Passionsblume,  Passion Flower,
Pommeranzschalen bitter,  Pommera bowls bitter,
Pestwurz,  butterbur,
Schafgarbe,  Yarrow,
Süßholzwurzel,  Licorice root,
Rosenwurz,  Rhodiola,
Rosenblüten,  Rose petals,
Schwertlilienwurzel,  Irises root,
Stiefmütterchen blaublühend  Pansy blue-flowering
Taigawurzel,  Siberian ginseng,
Teufelskralle,  Devil's Claw,
Wach holderbeeren,  Juniper berries,
Weidenrinde,  Willow bark,
Weihrauch,  Incense,
Wildhimbeerfrüchte chine.,  Wild raspberry fruits chine.,
Weintraubenkerne,  Grape seeds,
Wermut,  vermouth,
Zypressenspitzen  cypress tips
Vitamin A, Vitamin A,
Vitamin B 1 , Vitamin B 1,
Vitamin B 6, Vitamin B 6,
Vitamin B 12, Vitamin B12,
Folsäure folic acid
jeweils in der Menge von 1/1 / 1/1.000 ml bis 1.000 g / 1.000 ml each in the amount of 1/1/1/1000 ml to 1,000 g / 1,000 ml
4. 4th
Psychoneuroimmunium„PNI" nach Anspruch 1 , 2 und 3 dadurch gekennzeichnet, dass das Psychoneuroimmunium„PNI" folgende weitere Inhaltsstoffe hat: bärtiges Helmkraut,  Psychoneuroimmunium "PNI" according to claim 1, 2 and 3, characterized in that the Psychoneuroimmunium "PNI" has the following other ingredients: bearded helmet herb,
Oldenlandiakraut,  Oldenlandiakraut,
chinesische Zimtrinde/Cassia, Chinese cinnamon bark / Cassia,
Rotwurzsalbeiwurzel,  Rotwurzsalbeiwurzel,
Zitwerwurzel,  Zedoary,
chines. Engelwurz, Fieberstrauchwurzel, chines. Angelica, Fever shrub root,
Rohrkolbenpollen, Cattail pollen,
Windenglockenwurzel, Wind bells root,
koreanische Ginsengwurzel, Korean ginseng root,
Malayische Teefrucht/Harzklee, Malay tea tree / resin clover,
Traganthwurzel (Astragalus), Tragacanth Root (Astragalus),
chin. Odermennigkraut (pilosa), Chinese hymenoptera (pilosa),
Kiefernschwamm mit Wurzel, Pine sponge with root,
Hasenohrwurzel, Hasenohr root,
Goldfadenwurzelstock, Gold thread rhizome
Braunwurzel/Ningpo, Brown root / Ningpo,
Traubensilberkerzenwurzel, Black cohosh root,
Piment (Nelkenpfeffer), Allspice (clove pepper),
Rhabarberwurzel/Rhapontik Rhubarb root / Rhapontik
jeweils in der Menge von 1/1.000 mg / 1/1.000 ml bis 1.000 g / 1.000 ml each in the amount of 1 / 1,000 mg / 1 / 1,000 ml to 1,000 g / 1,000 ml
5. 5th
Psychoneuroimmunium„PNI" nach Anspruch 1 , 2, 3 und 4, dadurch gekennzeichnet, dass die Substanzen sowohl in fester Form als auch flüssig als Tabletten, Ampullen, Tabs, in Form von Heilpflastern, Zäpfchenform, Kapselform und Pulvern Verwendung finden.  Psychoneuroimmunium "PNI" according to claim 1, 2, 3 and 4, characterized in that the substances are used both in solid form and liquid as tablets, ampoules, tabs, in the form of medicinal plasters, suppository form, capsule form and powders.
PCT/EP2014/001769 2013-08-05 2014-06-27 Pni (psychoneuroimmunium) lobbyist cell protection WO2015018471A1 (en)

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