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WO2012108794A3 - Производные 1,2,4-триазол-з-илтиогликолевой кислоты для применения в терапии - Google Patents

Производные 1,2,4-триазол-з-илтиогликолевой кислоты для применения в терапии Download PDF

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Publication number
WO2012108794A3
WO2012108794A3 PCT/RU2012/000085 RU2012000085W WO2012108794A3 WO 2012108794 A3 WO2012108794 A3 WO 2012108794A3 RU 2012000085 W RU2012000085 W RU 2012000085W WO 2012108794 A3 WO2012108794 A3 WO 2012108794A3
Authority
WO
WIPO (PCT)
Prior art keywords
triazol
therapy
acid derivatives
ylthioglycolic
derivatives
Prior art date
Application number
PCT/RU2012/000085
Other languages
English (en)
French (fr)
Other versions
WO2012108794A2 (ru
Inventor
Андрей Александрович ВИННИК
Петр Олегович ФЕДИЧЕВ
Original Assignee
ХОЛИН, Максим Николаевич
НЕСТЕРУК, Владимир Викторович
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ХОЛИН, Максим Николаевич, НЕСТЕРУК, Владимир Викторович filed Critical ХОЛИН, Максим Николаевич
Publication of WO2012108794A2 publication Critical patent/WO2012108794A2/ru
Publication of WO2012108794A3 publication Critical patent/WO2012108794A3/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12—Oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Изобретение относится к производным 1,2,4-триазол-З-илтиогликолевой кислоты и их фармацевтически приемлемым солям, солевым аддуктам или сольватам, а также к содержащим их фармацевтическим композициям, для применения в терапии.
PCT/RU2012/000085 2011-02-10 2012-02-10 Производные 1,2,4-триазол-з-илтиогликолевой кислоты для применения в терапии WO2012108794A2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU2011104686/04A RU2011104686A (ru) 2011-02-10 2011-02-10 Производные 1,2,4-триазол-3-илтиогликолевой кислоты для применения в терапии
RU2011104686 2011-02-10

Publications (2)

Publication Number Publication Date
WO2012108794A2 WO2012108794A2 (ru) 2012-08-16
WO2012108794A3 true WO2012108794A3 (ru) 2012-10-26

Family

ID=46639113

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/RU2012/000085 WO2012108794A2 (ru) 2011-02-10 2012-02-10 Производные 1,2,4-триазол-з-илтиогликолевой кислоты для применения в терапии

Country Status (2)

Country Link
RU (1) RU2011104686A (ru)
WO (1) WO2012108794A2 (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2626003C2 (ru) * 2014-04-28 2017-07-21 Общество с ограниченной ответственностью "Квантум Фармасьютикалс" Амид 1,2,4-триазол-3-илтиогликолевой кислоты, обладающий противовирусной активностью, или его фармацевтически приемлемые соли, фармацевтические композиции и их применение для лечения и профилактики гриппа

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4564622A (en) * 1982-10-21 1986-01-14 Bayer Aktiengesellschaft Triazole derivative as an antiviral agent

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4564622A (en) * 1982-10-21 1986-01-14 Bayer Aktiengesellschaft Triazole derivative as an antiviral agent

Non-Patent Citations (12)

* Cited by examiner, † Cited by third party
Title
"Synthesis of 5-Aryl-2H-tetrazoles, 5-Aryl-2H-tetrazole-2-acetic Acids, and [(4-Phenyl-5-aryl-4H-1,2,4-triazol-3-yl)thio]acetic Acids as Possible Superoxide Scavengers and Antiinflammatory Agents.", J. MED. CHEM., vol. 27, 1984, pages 1565 - 1570 *
DATABASE ACS 10 March 2003 (2003-03-10), accession no. 97241-42-6 *
DATABASE ACS 11 October 2001 (2001-10-11), accession no. 61476-68-8 *
DATABASE ACS 12 March 2003 (2003-03-12), accession no. 97950-94-4 *
DATABASE ACS 14 March 2003 (2003-03-14), accession no. 99115-95-6 *
DATABASE ACS 17 November 2000 (2000-11-17), accession no. 03103-18-6 *
DATABASE ACS 17 November 2000 (2000-11-17), accession no. 03105-40-0 *
DATABASE ACS 19 April 2002 (2002-04-19), accession no. 06203-05-2 *
DATABASE ACS 19 January 2001 (2001-01-19), accession no. 15231-27-7 *
DATABASE ACS 20 November 2000 (2000-11-20), accession no. 03203-30-7 *
DATABASE ACS 20 November 2000 (2000-11-20), accession no. 03207-53-6 *
DATABASE ACS 5 December 2000 (2000-12-05), accession no. 06757-40-4 *

Also Published As

Publication number Publication date
WO2012108794A2 (ru) 2012-08-16
RU2011104686A (ru) 2012-08-20

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