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WO2012053006A8 - Improved oral fast dissolving films comprising combination of polymers and method of preparation thereof - Google Patents

Improved oral fast dissolving films comprising combination of polymers and method of preparation thereof Download PDF

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Publication number
WO2012053006A8
WO2012053006A8 PCT/IN2011/000715 IN2011000715W WO2012053006A8 WO 2012053006 A8 WO2012053006 A8 WO 2012053006A8 IN 2011000715 W IN2011000715 W IN 2011000715W WO 2012053006 A8 WO2012053006 A8 WO 2012053006A8
Authority
WO
WIPO (PCT)
Prior art keywords
combination
oral
polymers
preparation
water
Prior art date
Application number
PCT/IN2011/000715
Other languages
French (fr)
Other versions
WO2012053006A3 (en
WO2012053006A2 (en
Inventor
Rajesh Jain
Sarabjit Singh
Paramjit Singh
Mansi Saildesai
Original Assignee
Panacea Biotec Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Panacea Biotec Ltd filed Critical Panacea Biotec Ltd
Publication of WO2012053006A2 publication Critical patent/WO2012053006A2/en
Publication of WO2012053006A8 publication Critical patent/WO2012053006A8/en
Publication of WO2012053006A3 publication Critical patent/WO2012053006A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention relates to an oral film having reduced adherence to oral cavity comprising water-soluble polymer as an essential polymer base in combination with film former, wherein the ratio of water-soluble polymer to the film former is about 25: 1 to about 250: 1 that is suitable for delivering drugs from various pharmacological categories ranging from conventional small molecules to proteins or peptides. In particular the invention relates to oral films which are bioequivalent to conventional immediate release oral dosage forms and exhibiting one or more favorable properties such as fast dissolution time, improved drug loading, improved mechanical properties (burst strength, tensile strength, modules of elongation).
PCT/IN2011/000715 2010-10-18 2011-10-17 Improved oral fast dissolving films comprising combination of polymers and method of preparation thereof WO2012053006A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2887MU2010 2010-10-18
IN2887/MUM/2010 2010-10-18

Publications (3)

Publication Number Publication Date
WO2012053006A2 WO2012053006A2 (en) 2012-04-26
WO2012053006A8 true WO2012053006A8 (en) 2012-05-24
WO2012053006A3 WO2012053006A3 (en) 2012-08-02

Family

ID=45464052

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2011/000715 WO2012053006A2 (en) 2010-10-18 2011-10-17 Improved oral fast dissolving films comprising combination of polymers and method of preparation thereof

Country Status (1)

Country Link
WO (1) WO2012053006A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102860997A (en) * 2012-09-28 2013-01-09 天津市聚星康华医药科技有限公司 Ondansetron oral cavity instant membrane capable of sheltering taste and preparation method thereof

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KR102025238B1 (en) 2010-12-16 2019-09-25 선오비온 파마슈티컬스 인코포레이티드 Sublingual Films
US20150216798A1 (en) * 2012-08-17 2015-08-06 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Novel orally administered pharmaceutical formulations
WO2014042416A1 (en) * 2012-09-13 2014-03-20 주식회사 씨티씨바이오 Oral composition containing dapoxetin-free base
FR2997402B1 (en) * 2012-10-30 2016-02-26 Oniris WATER-SOLUBLE FILMS FOR PACKAGING SOLID COMPOSITIONS AND METHOD OF MANUFACTURE
FR2999086B1 (en) * 2012-12-10 2015-04-10 Ethypharm Sa ORAL AND / OR ORAL COMPOSITION IN FINE FILM FORM OF A LOW SOLUBLE ACTIVE INGREDIENT, PROCESS FOR PREPARING THE SAME AND USE THEREOF
KR102223105B1 (en) * 2013-04-11 2021-03-04 주식회사 씨티씨바이오 Film formulation containing tadalafil free base comprising polyethylene glycol based polymer and/or vinylpyrrolidone base polymer as dispersing agents
US11116769B2 (en) 2013-04-11 2021-09-14 Ctc Bio, Inc. Tadalafil free base-containing film dosage form containing polyethylene glycol-based polymer and/or vinyl pyrrolidone-based polymer as dispersion stabilizer
IN2013MU03658A (en) * 2013-11-21 2015-09-25 Akanksha Bindeshwari Prasad Yadav
MX370456B (en) * 2013-12-23 2019-12-13 Colgate Palmolive Co Film compositions for oral use.
NZ727834A (en) * 2014-06-24 2020-08-28 Taho Pharmaceuticals Ltd Fast acting orally disintegrating film
EP3111929B1 (en) * 2014-06-24 2018-08-29 Wooshin Labottach Co., Ltd. Oral disintegrating film formulation containing tadalafil and preparation method therefor
KR101538985B1 (en) * 2014-09-02 2015-07-24 주식회사 서울제약 Tadalafil Orally Disintegrating Film and Precess For Producing thereof
US10226450B2 (en) 2014-09-25 2019-03-12 Shilpa Medicare Limited Pharmaceutical film composition
KR20240036586A (en) * 2014-12-09 2024-03-20 어퀘스티브 테라퓨틱스, 인크. Linear polysaccharide based film products
WO2016172095A1 (en) 2015-04-21 2016-10-27 Cynapsus Therapeutics, Inc. Methods of treating parkinson's disease by administration of apomorphine to an oral mucosa
IL247161A0 (en) 2016-08-08 2016-12-29 Rubin Yoram Adhesive films for quick dissolution in managing oral conditions
US11154585B2 (en) * 2017-01-18 2021-10-26 Pharmathen S.A. Orodispersible film composition comprising enalapril for the treatment of hypertension in a pediatric population
DE102017107468B4 (en) * 2017-04-06 2019-02-21 Lts Lohmann Therapie-Systeme Ag PROCESS FOR PREPARING AN IN PARTICULAR ORAL, ACTIVE LAMINATE AND ACTIVE LAMINATE, IN PARTICULAR ORAL ACTIVE LAMINATE
US11464736B2 (en) 2019-07-23 2022-10-11 Unm Rainforest Innovations Thermally gelling drug formulations
US10973760B1 (en) 2020-07-21 2021-04-13 King Abdulaziz University Instantly dissolving buccal films
CN114432272B (en) * 2020-11-02 2024-05-28 上海现代药物制剂工程研究中心有限公司 Orosity membrane, racecadotril orosity membrane agent and preparation method thereof
WO2022192476A1 (en) 2021-03-09 2022-09-15 Aquestive Therapeutics, Inc. Dosage forms having equivalent biocomparable profiles
US20240408025A1 (en) * 2021-09-13 2024-12-12 Nutrition & Biosciences Usa 1, Llc A film-forming composition comprising pectin

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ITMI20022343A1 (en) 2002-11-05 2004-05-06 Biofarm Srl FAST DISSOLUTION FILM IN WATER, CONTAINING COSMETIC, AROMATIC, PHARMACEUTICAL OR FOOD SYSTEMS.
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102860997A (en) * 2012-09-28 2013-01-09 天津市聚星康华医药科技有限公司 Ondansetron oral cavity instant membrane capable of sheltering taste and preparation method thereof

Also Published As

Publication number Publication date
WO2012053006A3 (en) 2012-08-02
WO2012053006A2 (en) 2012-04-26

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