[go: up one dir, main page]

WO2011011382A4 - Devices, systems, and related methods for delivery of fluid to tissue - Google Patents

Devices, systems, and related methods for delivery of fluid to tissue Download PDF

Info

Publication number
WO2011011382A4
WO2011011382A4 PCT/US2010/042554 US2010042554W WO2011011382A4 WO 2011011382 A4 WO2011011382 A4 WO 2011011382A4 US 2010042554 W US2010042554 W US 2010042554W WO 2011011382 A4 WO2011011382 A4 WO 2011011382A4
Authority
WO
WIPO (PCT)
Prior art keywords
injection
distal end
shaft
fluid
tissue
Prior art date
Application number
PCT/US2010/042554
Other languages
French (fr)
Other versions
WO2011011382A1 (en
Inventor
Justin M. Crank
Original Assignee
Ams Research Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ams Research Corporation filed Critical Ams Research Corporation
Priority to AU2010276343A priority Critical patent/AU2010276343B2/en
Priority to EP10739755A priority patent/EP2456496A1/en
Priority to CA2757180A priority patent/CA2757180C/en
Publication of WO2011011382A1 publication Critical patent/WO2011011382A1/en
Publication of WO2011011382A4 publication Critical patent/WO2011011382A4/en
Priority to AU2015261555A priority patent/AU2015261555B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
    • A61M25/007—Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/02—Holding devices, e.g. on the body
    • A61M25/04—Holding devices, e.g. on the body in the body, e.g. expansible
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

Described are devices useful to inject fluid to tissue without the use of a needle, and related methods; the devices include one or a combination of features such as ejection orifices, distal end control features, or combinations of these; the systems can include a fluid delivery system having an injector source and an access device; the access device can comprise a minimally invasive, tubular delivery lumen such as a catheter or endoscope; the tube-like device further includes one or more apposing jets that are selectively fired to force the injection orifice of the tube-like device against the target tissue; selective firing can include a continuous firing during the injection to improve the efficiency of the treatment.

Claims

AMENDED CLAIMS received by the International Bureau on 21 January 2011 (21.01.2011)
1. A needleless injection device comprising
a flexible shaft comprising a proximal end, a distal end, a distal end tip, and an injection lumen extending from the proximal end to the distal end,
the distal end comprising first and second injection orifices spaced apart along a length of the shaft, at least one of the first and second injection orifices directed at a non-normal angle relative to a central axis of the shaft, and in communication with the injection lumen,
wherein the shaft is capable of ejecting a fluid stream from the injection orifices, the fluid stream being capable of being injected into tissue by penetrating a tissue surface as a fluid stream.
2. A needleless injection device according to claim 1 wherein the shaft comprises a sidewall extending from the proximal end to the distal end and at least one of the first and second injection orifices comprises an aperture passing through the sidewall.
3. A needleless injection device according to claim 1 or 2 wherein at least one of the first and second injection orifices are directed at an angle relative to the central axis of the shaft to provide converging streams of injection fluid.
4. A needleless injection device according to claim 1 or 2 wherein at least one of the first and second injection orifices are directed at an angle relative to the central axis of the shaft to provide diverging streams of injection fluid.
5. A needleless injection device according to claim 1 wherein
fluid ejected from the first and second injection orifices produces an injection force on the distal end, and
the distal end comprises at least one control orifice from which fluid can be ejected to produce a control force to oppose the injection force.
6. A needleless injection device according to claim 1 wherein
fluid ejected from the first and second injection orifices produces an injection force on the distal end, and
the distal end comprises a balloon to produce a control force to oppose the injection force.
7. A method of injecting tissue comprising
providing a needleless injection device according to any of claims 1 through 6,
providing an injectate at the proximal end and in communication with the injection lumen,
placing the first and second injection orifices near a tissue surface without penetrating the tissue surface,
pressurizing the injectate to cause the injectate to be ejected from the injection orifice as a fluid stream that passes through the tissue surface and disperses as fluid particles in tissue below the tissue surface.
8. A method according to claim 7 wherein ejection of fluid from the first and second injection orifices produces an injection force on the distal end.
9. A method according to claim 8 comprising at least partially opposing the injection force.
10. A method according to claim 9 wherein the injection force is opposed by One or more of a tissue holding tip, an opposing force produced by at least one control orifice, an opposing force produced by an injection orifice, and a balloon.
11. A method according to any of claims 7 through 10 comprising injecting bladder tissue or prostate tissue.
12. A needleless injection device according to any of claims 1 through 5 comprising an apposition device at the distal end.
13. A needleless injection device according to claim 12 wherein the apposition device comprises a balloon.
14. A needleless injection device according to claim 13 wherein the balloon is located at a distal end of the flexible shaft generally opposite an injection orifice.
15. A needleless injection device according to any of claims 1 through 6 and 12 through 14, wherein the first and a second injection orifices are located at different circumferential locations.
16. A needleless injection device according to any of claims 1 through 6 and 12 througli 15 wherein the device comprises a working shaft comprising a working shaft proximal end and a working shaft distal end.
17. The needleless injection device according to claim 16 wherein the working shaft comprises a working lumen extending between the working shaft proximal end and the working shaft distal end, and the flexible shaft is contained in the working lumen in a manner thai allows the flexible shaft lo move longitudinally within the working lumen.
18. A needleless injection device according to claim 16 or 17 wherein the working shaft comprising
a steerable distal end,
an end opening from which the flexible shaft distal end can be extended, fiber optics, and
a light source.

STATEMENT UNDER ARTICLE 19(1)

This communication is concurrently filed with Amendments Under Article 19 in connection with the above-identified international patent application.

New claims 12-18 are added.

No fee is believed to be necessary. However, in the event a fee is required, please notify us of the same.

PCT/US2010/042554 2009-07-20 2010-07-20 Devices, systems, and related methods for delivery of fluid to tissue WO2011011382A1 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2010276343A AU2010276343B2 (en) 2009-07-20 2010-07-20 Devices, systems, and related methods for delivery of fluid to tissue
EP10739755A EP2456496A1 (en) 2009-07-20 2010-07-20 Devices, systems, and related methods for delivery of fluid to tissue
CA2757180A CA2757180C (en) 2009-07-20 2010-07-20 Devices, systems, and related methods for delivery of fluid to tissue
AU2015261555A AU2015261555B2 (en) 2009-07-20 2015-11-24 Devices, systems, and related methods for delivery of fluid to tissue

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US22682809P 2009-07-20 2009-07-20
US22684609P 2009-07-20 2009-07-20
US22687109P 2009-07-20 2009-07-20
US61/226,846 2009-07-20
US61/226,828 2009-07-20
US61/226,871 2009-07-20

Publications (2)

Publication Number Publication Date
WO2011011382A1 WO2011011382A1 (en) 2011-01-27
WO2011011382A4 true WO2011011382A4 (en) 2011-06-03

Family

ID=43063759

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2010/042554 WO2011011382A1 (en) 2009-07-20 2010-07-20 Devices, systems, and related methods for delivery of fluid to tissue

Country Status (4)

Country Link
EP (1) EP2456496A1 (en)
AU (1) AU2010276343B2 (en)
CA (1) CA2757180C (en)
WO (1) WO2011011382A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2456488A2 (en) 2009-07-20 2012-05-30 AMS Research Corporation Needleless injection device components

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5180387A (en) * 1987-09-17 1993-01-19 Neurodynamics, Inc. Angled hole ventricular catheter with non-circular bore
US5643228A (en) * 1995-11-13 1997-07-01 Uresil Corporation Catheter
JP2001314514A (en) * 2000-05-08 2001-11-13 Saito Satoshi Through-lumen type treating tool guiding catheter
US6969373B2 (en) * 2001-04-13 2005-11-29 Tricardia, Llc Syringe system
JP4229621B2 (en) * 2002-03-05 2009-02-25 修 加藤 Chemical injection catheter
US8262605B2 (en) 2004-12-09 2012-09-11 Ams Research Corporation Needleless delivery systems
US20090312696A1 (en) 2005-12-28 2009-12-17 Copa Vincent G Devices, Systems, and Related Methods for Delivery of Fluid to Tissue
US20080119823A1 (en) 2006-11-21 2008-05-22 Crank Justin M Injection Tube for Jet Injection Device
US8723108B1 (en) 2012-10-19 2014-05-13 Agilent Technologies, Inc. Transient level data acquisition and peak correction for time-of-flight mass spectrometry

Also Published As

Publication number Publication date
AU2010276343A1 (en) 2011-10-27
WO2011011382A1 (en) 2011-01-27
AU2010276343B2 (en) 2015-08-27
CA2757180C (en) 2017-05-23
EP2456496A1 (en) 2012-05-30
CA2757180A1 (en) 2011-01-27

Similar Documents

Publication Publication Date Title
WO2010065133A4 (en) Devices, systems, and related methods for delivery of fluid to tissue
AU2016225798B2 (en) Miniature fluid atomizer
WO2007143288A3 (en) Systems for injecting media contrast
WO2008124482A3 (en) Apparatus and method for treatment of ethmoids
CA2643262A1 (en) Curable material delivery device
KR102017563B1 (en) Injection Device Of Medical Fluid
US20150246178A1 (en) Devices, systems, and related methods for delivery of fluid to tissue
CN101983038A (en) Water jet surgical instrument
WO2007133959A3 (en) Device for treating chronic total occlusion
WO2009089409A3 (en) Intravitreal injection system having coaxial cannulae and use thereof
WO2007111908A3 (en) Apparatus for treating vulnerable plaque
WO2011041720A3 (en) Method and apparatus for manipulating movement of a micro-catheter
WO2009024521A4 (en) Injection apparatus for making an injection at a predetermined depth in the skin
WO2009089094A3 (en) Implantable drug-delivery devices, and apparatus and methods for refilling the devices
WO2011038080A3 (en) Apparatus and method to deliver a microchip
WO2009135213A3 (en) Laser energy devices and methods for soft tissue removal
WO2012083176A3 (en) High-pressure pneumatic injection system and method
WO2008039355A3 (en) Curable material delivery device with a rotatable supply section
EP3718590A3 (en) Catheters and systems useful for delivery of material to the lung
WO2006081026A3 (en) Multiple needle injection catheter and method of use of same
WO2017079325A3 (en) Injection devices and systems and methods for using them
WO2011011382A4 (en) Devices, systems, and related methods for delivery of fluid to tissue
WO2006009839A3 (en) Intradermal injection system for injecting dna-based injectables into humans
WO2019067790A3 (en) Injection devices and systems and methods for using them
KR102051796B1 (en) Bryan retractor

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 10739755

Country of ref document: EP

Kind code of ref document: A1

WWE Wipo information: entry into national phase

Ref document number: 2757180

Country of ref document: CA

ENP Entry into the national phase in:

Ref document number: 2010276343

Country of ref document: AU

Date of ref document: 20100720

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 2010739755

Country of ref document: EP

NENP Non-entry into the national phase in:

Ref country code: DE