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WO2010063995A3 - Telmisartan with diuretic formulations - Google Patents

Telmisartan with diuretic formulations Download PDF

Info

Publication number
WO2010063995A3
WO2010063995A3 PCT/GB2009/002791 GB2009002791W WO2010063995A3 WO 2010063995 A3 WO2010063995 A3 WO 2010063995A3 GB 2009002791 W GB2009002791 W GB 2009002791W WO 2010063995 A3 WO2010063995 A3 WO 2010063995A3
Authority
WO
WIPO (PCT)
Prior art keywords
diuretic
telmisartan
formulations
mantle
formulated
Prior art date
Application number
PCT/GB2009/002791
Other languages
French (fr)
Other versions
WO2010063995A2 (en
Inventor
Peter Henry Robert Persicaner
Rahul Sareen
Original Assignee
Arrow International Limited
Tabatznik, Anthony, S.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arrow International Limited, Tabatznik, Anthony, S. filed Critical Arrow International Limited
Publication of WO2010063995A2 publication Critical patent/WO2010063995A2/en
Publication of WO2010063995A3 publication Critical patent/WO2010063995A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A mantle tablet is formulated, comprising a telmisartan core surrounded by a diuretic-containing mantle.
PCT/GB2009/002791 2008-12-04 2009-12-01 Telmisartan with diuretic formulations WO2010063995A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0822170.7 2008-12-04
GBGB0822170.7A GB0822170D0 (en) 2008-12-04 2008-12-04 Telmisartan with diuretic formulations
GB0913884.3 2009-08-10
GBGB0913884.3A GB0913884D0 (en) 2008-12-04 2009-08-10 Telmisartan with diuretic formulations

Publications (2)

Publication Number Publication Date
WO2010063995A2 WO2010063995A2 (en) 2010-06-10
WO2010063995A3 true WO2010063995A3 (en) 2010-11-25

Family

ID=40289506

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2009/002791 WO2010063995A2 (en) 2008-12-04 2009-12-01 Telmisartan with diuretic formulations

Country Status (2)

Country Link
GB (2) GB0822170D0 (en)
WO (1) WO2010063995A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2612658A1 (en) * 2012-01-05 2013-07-10 Laboratorios Lesvi, S.L. Pharmaceutical compositions of 4'-[(1,4'dimethyl-2'-propyl[2,6'-bi-1h-benzimidazol]-1'-yl)methyl]-[1,1'-biphenyl]-2-carboxylic acid and is 6-chloro-3,4-dihydro-2h-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxide

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006063737A1 (en) * 2004-12-17 2006-06-22 Boehringer Ingelheim International Gmbh Combination therapy comprising telmisartan and hydrochlorothiazide
WO2007144175A2 (en) * 2006-06-16 2007-12-21 Lek Pharmaceuticals D.D. Pharmaceutical composition comprising hydrochlorothiazide and telmisartan
CN101134032A (en) * 2007-09-24 2008-03-05 湖北丝宝药业有限公司 Compound preparations for treating hypertension and method for preparing the same
WO2009058950A2 (en) * 2007-10-30 2009-05-07 Dr. Reddy's Laboratories Ltd. Pharmaceutical formulations comprising telmisartan and hydrochlorothiazide

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006063737A1 (en) * 2004-12-17 2006-06-22 Boehringer Ingelheim International Gmbh Combination therapy comprising telmisartan and hydrochlorothiazide
WO2007144175A2 (en) * 2006-06-16 2007-12-21 Lek Pharmaceuticals D.D. Pharmaceutical composition comprising hydrochlorothiazide and telmisartan
CN101134032A (en) * 2007-09-24 2008-03-05 湖北丝宝药业有限公司 Compound preparations for treating hypertension and method for preparing the same
WO2009058950A2 (en) * 2007-10-30 2009-05-07 Dr. Reddy's Laboratories Ltd. Pharmaceutical formulations comprising telmisartan and hydrochlorothiazide

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 10 April 2008 (2008-04-10), XP002602665, retrieved from stn Database accession no. 148:363419 *

Also Published As

Publication number Publication date
WO2010063995A2 (en) 2010-06-10
GB0822170D0 (en) 2009-01-14
GB0913884D0 (en) 2009-09-16

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