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WO2009127840A1 - Magnetic stimulators and stimulating coils - Google Patents

Magnetic stimulators and stimulating coils Download PDF

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Publication number
WO2009127840A1
WO2009127840A1 PCT/GB2009/001001 GB2009001001W WO2009127840A1 WO 2009127840 A1 WO2009127840 A1 WO 2009127840A1 GB 2009001001 W GB2009001001 W GB 2009001001W WO 2009127840 A1 WO2009127840 A1 WO 2009127840A1
Authority
WO
WIPO (PCT)
Prior art keywords
coolant
coil
magnetic
stimulating
coil device
Prior art date
Application number
PCT/GB2009/001001
Other languages
French (fr)
Inventor
Mark Phillips
Original Assignee
The Magstim Company Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Magstim Company Limited filed Critical The Magstim Company Limited
Publication of WO2009127840A1 publication Critical patent/WO2009127840A1/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00Magnetotherapy
    • A61N2/004Magnetotherapy specially adapted for a specific therapy
    • A61N2/006Magnetotherapy specially adapted for a specific therapy for magnetic stimulation of nerve tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00Magnetotherapy
    • A61N2/02Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets

Definitions

  • a magnetic stimulator for the magnetic stimulation of neuro-muscular tissue comprises: a stimulating coil device; a charging circuit; a capacitor; a discharge control for allowing discharge of the capacitor through the stimulating coil device; and a coolant supply system which supplies coolant to the stimulating coil device; wherein the stimulating coil device comprises an inner coil and an outer coil and the cooling system is configured to supply coolant to the inner coil such that the coolant flows in a first flow direction to cool the inner coil and to simultaneously supply coolant to the outer coil such that the coolant flows in an opposite second flow direction to cool the outer coil.
  • a magnetic stimulating coil device for the magnetic stimulation of neuro-muscular tissue comprises: an inner coil; and an outer coil; wherein the inner and outer coils each comprise a coolant conduit configured for separate connection to a coolant supply system such that coolant can simultaneously flow in a first direction through the coolant conduit of the inner coil and in an opposite direction through the coolant conduit of the outer coil.
  • the coolant conduits are connected to a heat exchanger or peltier device and a pump is connected to recirculate the coolant through the heat exchanger/peltier device and the coolant conduits.
  • FIG. 1 is a schematic circuit diagram of a magnetic stimulator
  • This particular example has a high-voltage power supply 1 which charges a reservoir capacitor 2. Charge is transferred from the reservoir capacitor, substantially independently of the charging rate of the reservoir capacitor, via a transfer capacitor 5 to a 'discharge' capacitor 9, which at appropriate intervals is discharged into a stimulating coil 11.
  • the transfer capacitor 5 is part of a charge pump which includes a unidirectional switch 3, a series inductor 4, the transfer capacitor 5, a reverse diode 6 in parallel with the capacitor 5, a series inductor 7 and a switching system 8, which comprises controlled rectifiers 8a, 8b, 8c and 8d.
  • the discharge of the capacitor 9 is controlled by the switching system 10 comprising controlled rectifiers 10a, 10b, 10c and 1Od.
  • FIG. 3 illustrates the coil in section, the section being taken on the line X-X in FIG. 2 or FIG. 4.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Magnetic Treatment Devices (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)

Abstract

A magnetic stimulator for the magnetic stimulation of brain or muscular tissue including a stimulating coil device, a charging circuit, a capacitor, a discharge control for allowing discharge of the capacitor through the stimulating coil device and a coolant supply system which supplies coolant to the stimulating coil device. The stimulating coil device has an inner coil and an outer coil and the coolant supply system is configured to supply coolant to the inner coil such that the coolant flows in a first flow direction to cool the inner coil and to simultaneously supply coolant to the outer coil such that the coolant flows in an opposite second flow direction to cool the outer coil.

Description

MAGNETIC STIMULATORS AND STIMULATING COILS
Field of the Invention
This invention relates to magnetic stimulators, particularly for the magnetic stimulation of brain and/or muscular tissue. Magnetic stimulators of this kind achieve stimulation by the creation of a rapidly changing magnetic field, for example of the order of 20 kiloTesla per second in the vicinity of the tissue. Electric currents thereby induced in the tissue cause stimulation thereof
Background to the invention
Known magnetic stimulators generally comprise a charging circuit for a "discharge" capacitor, a discharge control such as a controlled rectifier for allowing discharge of the capacitor through a stimulating coil, and other circuit elements for limiting the effect of undesirable electrical transients. Heat is generated in the stimulating coil during use so the coil generally requires cooling to ensure comfort for the patient. GB 2415632 describes a known magnetic stimulator with cooling system.
An object of the invention is to provide effective cooling for a magnetic stimulator.
Summary of the invention
According to one aspect of the invention, a magnetic stimulator for the magnetic stimulation of neuro-muscular tissue comprises: a stimulating coil device; a charging circuit; a capacitor; a discharge control for allowing discharge of the capacitor through the stimulating coil device; and a coolant supply system which supplies coolant to the stimulating coil device; wherein the stimulating coil device comprises an inner coil and an outer coil and the cooling system is configured to supply coolant to the inner coil such that the coolant flows in a first flow direction to cool the inner coil and to simultaneously supply coolant to the outer coil such that the coolant flows in an opposite second flow direction to cool the outer coil.
The applicants have found that the cooling configuration of the invention provides particularly effective cooling.
According to another aspect of the invention a magnetic stimulating coil device for the magnetic stimulation of neuro-muscular tissue comprises: an inner coil; and an outer coil; wherein the inner and outer coils each comprise a coolant conduit configured for separate connection to a coolant supply system such that coolant can simultaneously flow in a first direction through the coolant conduit of the inner coil and in an opposite direction through the coolant conduit of the outer coil.
According to a further aspect of the invention, a method of cooling a magnetic stimulating coil device, the magnetic stimulating coil device being for the magnetic stimulation of neuro-muscular tissue, comprises the step of supplying coolant in a first flow direction to an inner coil of the magnetic stimulating coil device and simultaneously supplying coolant to an outer coil of the magnetic stimulating coil in an opposite flow direction.
Preferably the inner and outer coils each have an associated coolant conduit, the coolant conduits being separately connected to the coolant supply system and more preferably each coolant conduit comprises a flexible hollow member.
The inner and outer coils may comprise a flexible conductor which extends through the respective flexible hollow members.
The inner and outer coils may be multiple turn coils, with both the flexible conductor and the flexible hollow members through which the flexible conductor extends being wound in multiple turns. The turns of both the inner and outer coils are preferably disposed to lie generally in a common plane. The coils may be embedded in a flexible cover comprising a flexible covering material, which is preferably an insulating material.
Preferably the coils and the flexible cover can be adjusted by hand to conform the coil to the contours of a selected part of the human body.
Preferably the inner and outer coils each comprise a multiple turn coil in which the turns are disposed to lie generally in a common plane and are supported by the flexible cover in that plane.
Preferably the flexible cover includes at least one sensor for sensing the temperature of the coil or coils, and said sensor is coupled to prevent current flow through the coils on the detection of a temperature above a limit.
Preferably the flexible cover is plastically flexible or elastically flexible.
Preferably the flexible cover has a generally flat disc shape.
Preferably the coolant conduits are connected to a heat exchanger or peltier device and a pump is connected to recirculate the coolant through the heat exchanger/peltier device and the coolant conduits.
The coolant may be water but may be a liquid of high thermal conductivity and low electrical conductivity and may be an organic (carbon-based) liquid such as a fluorocarbon. Alternatively the coolant could be a gas.
Exemplary embodiments of the invention will now be described in detail with reference to the accompanying drawings.
Brief Description Of The Drawings
FIG. 1 is a schematic circuit diagram of a magnetic stimulator;
FIG. 2 is a schematic diagram of a magnetic stimulator in accordance with the invention; FIG. 3 schematically shows a cross-section through the embodiment of Fig 2 or Fig. 4. FIG.' s 4, 5 and 6 represent views of a coil, shown from the rear, side and front respectively. Detailed Description
FIG. 1 of the drawings illustrates for the sake of completeness the electrical circuit of one form of magnetic stimulator suitable for use in the present invention. The particular example is one of several different stimulators which are the subject of, and are more fully described in, U.S. Pat. No. 5,766,124 to Poison.
This particular example has a high-voltage power supply 1 which charges a reservoir capacitor 2. Charge is transferred from the reservoir capacitor, substantially independently of the charging rate of the reservoir capacitor, via a transfer capacitor 5 to a 'discharge' capacitor 9, which at appropriate intervals is discharged into a stimulating coil 11. The transfer capacitor 5 is part of a charge pump which includes a unidirectional switch 3, a series inductor 4, the transfer capacitor 5, a reverse diode 6 in parallel with the capacitor 5, a series inductor 7 and a switching system 8, which comprises controlled rectifiers 8a, 8b, 8c and 8d. The discharge of the capacitor 9 is controlled by the switching system 10 comprising controlled rectifiers 10a, 10b, 10c and 1Od. The discharge current may be in either direction through the coil 11, which has an earth connection. Discharge pulses, of magnitude and frequency which are controllable by the switching systems 8 and 10, flow through the coil 11. Typically the instantaneous current may be of the order of 5 IcA, i.e. considerably in excess of 1 kA; the rms value of a typical pulse train may be hundreds of amps, such as 400 A.
FIG. 2 illustrates the physical components of an embodiment of the magnetic stimulator. The magnetic stimulating coil device 11 comprises inner coil 12 and outer coil 13. The inner coil 12 comprises a flexible conductor 11a disposed inside an elongate flexible tube 17 which conveys a fluid coolant. The outer coil 13 comprises a flexible conductor 11a disposed inside elongate flexible tube 18. The flexible conductor 11a may (for example) be copper wire having a diameter in the range 2.5 to 3 mm. In this embodiment, the middle region 1 Ib of the flexible conductor exits tube 17 before tube 17 connects with the heat exchanger and enters tube 18 before tube 18 connects with the heat exchanger. The conductor 1 Ia is preferably self-supporting and preferably has an insulating cover (not shown). The conductor 11a constituting the electrical element of the magnetic coil stimulating device 11 is connected as shown in FIG. 1 to the remainder of the stimulator. The stimulator 16 is for example as described with reference to FIG. 1.
Respective ends of the flexible tubes 17 and 18 are connected to the pump 19 and the heat exchanger or peltier device 20. The flexible tubes 17 and 18 are connected to allow a pump 19 to simultaneously pump fluid coolant through the tubes 17 and 18 such that, in use, the direction of flow in the tubes is opposed, as indicated by the arrows A and B. Thus if the coolant flow in tube 17 is clockwise then the flow in tube 18 will be anti- clockwise. Alternatively the system could be configured so that the coolant flow in tube 17 was in an anticlockwise direction whilst the flow in tube 18 was in a clockwise direction. The coolant fluid then enters a heat exchanger or a peltier device shown at 20.
Coolant from the heat exchanger or peltier device 20 flows to a reservoir 21 connected to the pump 19 and is recirculated through the tubes 17 and 18 during the operation of the stimulator.
FIG. 3 illustrates the coil in section, the section being taken on the line X-X in FIG. 2 or FIG. 4.
The inner 12 and outer 13 coils, comprising the wound conductor 11a and its surrounding wound flexible tubes 17 and 18 are encapsulated in the flexible, silicone rubber moulded disc-shaped cover 22. The tubes 17 and 18 maybe a silicone plastic material. The cover 22 has on its rear side a bulge 26 which accommodates the lead-in and lead-out parts of the flexible conductor 11 a in its tubes 17 and 18. The coolant flows along the space 27 between the conductor 11a and the surrounding tube 17 or 18. As previously mentioned above the flexible conductor may have an insulating and coolant resistant coating.
FIGS. 4-6 are different views of the cooled coil's general construction. The conductor 11a in the tubes 17 and 18 extends along and within the flexible elongate conduit 32 which comprises two end connectors 32a and 32b and an intermediate part comprising a ribbed plastics tube 32c. The end connector 32a is adapted in any convenient manner for connection to the connection box. The other end 32b is connected to a generally discshaped flexible covering material within which the turns of the coil are located in the same plane. FIG. 4 illustrates the λrearΛ of the coil, i.e. that which faces away from the patient in use. FIG. 5 illustrates a side view, showing the flat character of the covering material 22 in its original unflexed state. FIG. 6 illustrates the coil head form the front, i.e. that which is adjacent the patient in use.
Embedded in the flexible cover 22 and close to its front surface are temperature sensors 23 with electrical connections 24 that extend back along the conduit to the stimulator. Shown schematically is a safety switch 25 (FIG. 2) which in any convenient manner can disable the stimulator, to prevent current flow through the coil, if the sensed temperature is too high.
There may be flow detectors within the coolant circuit comprising the pump, heat exchanger, reservoir and the connecting conduits. Accordingly if the coolant flow reduces to below some pre-set value the application of current to the stimulating coil would be prevented. This is another safety feature to ensure that a thermally hazardous condition is avoided. By way of example a flow detector 26 within the coolant circuit is shown diagrammatically at 26 and is coupled to the safety switch 25.
Other forms of cooling system may be employed within the scope of the present invention. Rather than having the conductor disposed in the coolant conduit as specifically described, the multiple windings of the inner coil may be disposed within one single outer tube whilst the multiple windings of outer coil may also be disposed within another single outer tube with the coolant being driven simultaneously in opposing directions through the outer tubes. Alternatively the inner and outer coils may be disposed adjacent cooling conduits through which coolant is driven in opposing directions. In a further alternative embodiment, the conducting elements of the inner and outer coils could be hollow and define conduits through which coolant may be driven simultaneously in opposite directions. A variety of materials would be suitable for the cover 22. A silicone rubber compound may be used. The degree of hardness of the rubber may be chosen according to the desired elasticity of the flexure; a hard silicone rubber would be appropriate for an elastic covering material and a softer silicone rubber if the covering material is intended to flex plastically, the shape being maintained by the flexible copper wire inside the sheath.

Claims

Claims
1. A magnetic stimulator for the magnetic stimulation of brain or muscular tissue comprising: a stimulating coil device; a charging circuit; a capacitor; a discharge control for allowing discharge of the capacitor through the stimulating coil device; and a coolant supply system which supplies coolant to the stimulating coil device; wherein the stimulating coil device comprises an inner coil and an outer coil and the coolant supply system is configured to supply coolant to the inner coil such that the coolant flows in a first flow direction to cool the inner coil and to simultaneously supply coolant to the outer coil such that the coolant flows in an opposite second flow direction to cool the outer coil.
2. A magnetic stimulator according to claim 1 wherein the inner and outer coils each have an associated coolant conduit, the coolant conduits being separately connected to the coolant supply system.
3. A magnetic stimulator according to claim 2 wherein each coolant conduit comprises a flexible hollow member.
4. A magnetic stimulator according to claim 3 wherein the inner and outer coils comprise a flexible conductor which extends through the respective flexible hollow members.
5. A magnetic stimulating coil device for the magnetic stimulation of brain or muscular tissue, the stimulating coil device comprising: an inner coil; an outer coil; wherein the inner and outer coils each comprise a coolant conduit configured for separate connection to a coolant supply system such that coolant can simultaneously flow in a first direction through the coolant conduit of the inner coil and in an opposite direction through the coolant conduit of the outer coil.
6. A magnetic stimulating coil device according to claim 5 wherein each coolant conduit comprises a flexible hollow member.
7. A magnetic stimulating coil device according to claim 6 wherein the inner and outer coils comprise a flexible conductor which extends through the respective flexible hollow member.
8. A method of cooling a magnetic stimulating coil device, the magnetic stimulating coil device being for the magnetic stimulation of brain or muscular tissue, the method comprising the step of supplying coolant in a first flow direction to an inner coil of the magnetic stimulating coil device and simultaneously supplying coolant to an outer coil of the magnetic stimulating coil in an opposite flow direction.
9. A magnetic stimulator and/or a magnetic stimulating coil device and/or a method of cooling a magnetic stimulating coil device substantially as hereinbefore described and with reference to the accompanying drawings.
PCT/GB2009/001001 2008-04-17 2009-04-17 Magnetic stimulators and stimulating coils WO2009127840A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0806999A GB2459157B (en) 2008-04-17 2008-04-17 Magnetic stimulators and stimulators coils
GB0806999.9 2008-04-17

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WO2009127840A1 true WO2009127840A1 (en) 2009-10-22

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Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104056358A (en) * 2014-06-12 2014-09-24 中国科学院电工研究所 Magnetic stimulator cooling device
CN107510891A (en) * 2017-07-24 2017-12-26 深圳英智科技有限公司 A kind of coil block and magnetic stimulator
CN110975152A (en) * 2019-12-17 2020-04-10 华中科技大学 A continuous working magnetic stimulation device and method
US11794029B2 (en) 2016-07-01 2023-10-24 Btl Medical Solutions A.S. Aesthetic method of biological structure treatment by magnetic field
US11806528B2 (en) 2020-05-04 2023-11-07 Btl Healthcare Technologies A.S. Device and method for unattended treatment of a patient
US11826565B2 (en) 2020-05-04 2023-11-28 Btl Healthcare Technologies A.S. Device and method for unattended treatment of a patient
US11878162B2 (en) 2016-05-23 2024-01-23 Btl Healthcare Technologies A.S. Systems and methods for tissue treatment
US11883643B2 (en) 2016-05-03 2024-01-30 Btl Healthcare Technologies A.S. Systems and methods for treatment of a patient including RF and electrical energy
US11896816B2 (en) 2021-11-03 2024-02-13 Btl Healthcare Technologies A.S. Device and method for unattended treatment of a patient
US12064163B2 (en) 2021-10-13 2024-08-20 Btl Medical Solutions A.S. Methods and devices for aesthetic treatment of biological structures by radiofrequency and magnetic energy
US12076576B2 (en) 2019-04-11 2024-09-03 Btl Medical Solutions A.S. Methods and devices for aesthetic treatment of biological structures by radiofrequency and magnetic energy
US12109427B2 (en) 2016-07-01 2024-10-08 Btl Medical Solutions A.S. Aesthetic method of biological structure treatment by magnetic field
US12109426B2 (en) 2016-05-10 2024-10-08 Btl Medical Solutions A.S. Aesthetic method of biological structure treatment by magnetic field
US12156689B2 (en) 2019-04-11 2024-12-03 Btl Medical Solutions A.S. Methods and devices for aesthetic treatment of biological structures by radiofrequency and magnetic energy
US12274494B2 (en) 2016-08-16 2025-04-15 Btl Healthcare Technologies A.S. Treatment device

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56115506A (en) * 1980-02-18 1981-09-10 Hitachi Ltd Toroidal coil
US4657723A (en) * 1982-02-08 1987-04-14 Fdx Patents Holding Company, N.V. Method and apparatus for distributing coolant in toroidal field coils
JP2004215419A (en) * 2003-01-06 2004-07-29 Nikon Corp Linear motor, cooling method and stage device for linear motor, and aligner
GB2415632A (en) * 2004-07-01 2006-01-04 Magstim Co Ltd Flexible induction coil for magnetic neuro-muscular stimulation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10046275A1 (en) * 2000-09-19 2002-03-28 Albrecht Struppler Magnetic coil with interwoven spiral of two conductors with one hollow conductor carrying a coolant, so that a high magnetic field can be generated at a relatively low temperature, for use in nerve stimulation

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56115506A (en) * 1980-02-18 1981-09-10 Hitachi Ltd Toroidal coil
US4657723A (en) * 1982-02-08 1987-04-14 Fdx Patents Holding Company, N.V. Method and apparatus for distributing coolant in toroidal field coils
JP2004215419A (en) * 2003-01-06 2004-07-29 Nikon Corp Linear motor, cooling method and stage device for linear motor, and aligner
GB2415632A (en) * 2004-07-01 2006-01-04 Magstim Co Ltd Flexible induction coil for magnetic neuro-muscular stimulation

Cited By (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104056358A (en) * 2014-06-12 2014-09-24 中国科学院电工研究所 Magnetic stimulator cooling device
US11883643B2 (en) 2016-05-03 2024-01-30 Btl Healthcare Technologies A.S. Systems and methods for treatment of a patient including RF and electrical energy
US12151120B2 (en) 2016-05-10 2024-11-26 Btl Medical Solutions A.S. Aesthetic method of biological structure treatment by magnetic field
US12109426B2 (en) 2016-05-10 2024-10-08 Btl Medical Solutions A.S. Aesthetic method of biological structure treatment by magnetic field
US11896821B2 (en) 2016-05-23 2024-02-13 Btl Healthcare Technologies A.S. Systems and methods for tissue treatment
US11878162B2 (en) 2016-05-23 2024-01-23 Btl Healthcare Technologies A.S. Systems and methods for tissue treatment
US11794029B2 (en) 2016-07-01 2023-10-24 Btl Medical Solutions A.S. Aesthetic method of biological structure treatment by magnetic field
US12109427B2 (en) 2016-07-01 2024-10-08 Btl Medical Solutions A.S. Aesthetic method of biological structure treatment by magnetic field
US12274494B2 (en) 2016-08-16 2025-04-15 Btl Healthcare Technologies A.S. Treatment device
CN107510891A (en) * 2017-07-24 2017-12-26 深圳英智科技有限公司 A kind of coil block and magnetic stimulator
US12156689B2 (en) 2019-04-11 2024-12-03 Btl Medical Solutions A.S. Methods and devices for aesthetic treatment of biological structures by radiofrequency and magnetic energy
US12076576B2 (en) 2019-04-11 2024-09-03 Btl Medical Solutions A.S. Methods and devices for aesthetic treatment of biological structures by radiofrequency and magnetic energy
CN110975152A (en) * 2019-12-17 2020-04-10 华中科技大学 A continuous working magnetic stimulation device and method
US11813451B2 (en) 2020-05-04 2023-11-14 Btl Healthcare Technologies A.S. Device and method for unattended treatment of a patient
US12029905B2 (en) 2020-05-04 2024-07-09 Btl Healthcare Technologies A.S. Device and method for unattended treatment of a patient
US11878167B2 (en) 2020-05-04 2024-01-23 Btl Healthcare Technologies A.S. Device and method for unattended treatment of a patient
US11826565B2 (en) 2020-05-04 2023-11-28 Btl Healthcare Technologies A.S. Device and method for unattended treatment of a patient
US11806528B2 (en) 2020-05-04 2023-11-07 Btl Healthcare Technologies A.S. Device and method for unattended treatment of a patient
US12311170B2 (en) 2020-05-04 2025-05-27 Btl Healthcare Technologies A.S. Device and method for unattended treatment of a patient
US12064163B2 (en) 2021-10-13 2024-08-20 Btl Medical Solutions A.S. Methods and devices for aesthetic treatment of biological structures by radiofrequency and magnetic energy
US11896816B2 (en) 2021-11-03 2024-02-13 Btl Healthcare Technologies A.S. Device and method for unattended treatment of a patient
US12115365B2 (en) 2021-11-03 2024-10-15 Btl Healthcare Technologies A.S. Device and method for unattended treatment of a patient

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Publication number Publication date
GB0806999D0 (en) 2008-05-21
GB2459157B (en) 2010-10-13
GB2459157A (en) 2009-10-21

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