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WO2009007999A2 - Composition solide non poussiéreuse à écoulement libre, stable dans des conditions de stockage, et procédé de préparation - Google Patents

Composition solide non poussiéreuse à écoulement libre, stable dans des conditions de stockage, et procédé de préparation Download PDF

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Publication number
WO2009007999A2
WO2009007999A2 PCT/IN2008/000271 IN2008000271W WO2009007999A2 WO 2009007999 A2 WO2009007999 A2 WO 2009007999A2 IN 2008000271 W IN2008000271 W IN 2008000271W WO 2009007999 A2 WO2009007999 A2 WO 2009007999A2
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WIPO (PCT)
Prior art keywords
free
flowing
liquid
granules
formulation
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Application number
PCT/IN2008/000271
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English (en)
Other versions
WO2009007999A3 (fr
Inventor
Jaidev Rajnikant Shroff
Vikram Rajnikant Shroff
Prakash Mahadey Jadhav
Sujata Dhondiram Desai
Original Assignee
United Phosphorus Limted
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Application filed by United Phosphorus Limted filed Critical United Phosphorus Limted
Publication of WO2009007999A2 publication Critical patent/WO2009007999A2/fr
Publication of WO2009007999A3 publication Critical patent/WO2009007999A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/12—Powders or granules
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N53/00—Biocides, pest repellants or attractants, or plant growth regulators containing cyclopropane carboxylic acids or derivatives thereof

Definitions

  • the proposed invention relates to a non dusty, free flowing, storage stable solid composition.
  • This invention particularly relates to a non dusty, free flowing, storage stable solid composition comprising of at least one pesticide from pyrethroid class like cypermethrin, fenvalerate, permethrin, alphacypermethrin, betacypermethrin, zetacypermethrin, deltamethrin, cyfluthrin, low melting solid pyrethroids like bifenthrin, lambda cyhalothrin, and/or bioresmethrin, more particularly a high viscous liquid insecticide like permethrin.
  • this invention relates to a stable composition with improved properties of dispersibility and suspensibility brought about by a combination of inert ingredients silica and kaolin along with block copolymer of ethylene oxide and propylene oxide in specific proportions.
  • the present invention also relates to a process of preparing the said composition.
  • Solid compositions like granules are mainly produced by methods such as kneading, extrusion granulation, impregnation, coating etc.
  • Granules are more frequently applied to water surface or soil than directly applied to target crops. After application to water surface or soil, the active ingredient of granules dissolves/disperses in water or vaporizes to reach its action sites and displays the effect. It is therefore required that the same water dispersibility and suspensibility as those at the time of formulation are maintained even after long term storage.
  • Dry powdery (like wettable powder WP and others) composition has disadvantages like presence of sediment at the bottom of dilution tank, choking of nozzle while spraying, lumping during storage and drift problem at the time of production, packing, transportation, storage, handling, dilution and use.
  • the composition involves the use of organic solvents like petroleum ether, hydrocarbon solvents, xylene, isopropyl alcohol etc., which may cause further problems like toxicity, irritation to human body and /or other associated problems due to their physico-chemical properties like flash point, solvency with other materials, flammable and reactive nature.
  • organic solvents like petroleum ether, hydrocarbon solvents, xylene, isopropyl alcohol etc.
  • Suitable as liquid solvents are aromatic hydrocarbons, such as xylene, toluene or alkyl naphthalenes; chlorinated aromatic hydrocarbons and chlorinated aliphatic hydrocarbons, such as chlorobenzenes, methylene chloride; aliphatic hydrocarbons, such as cyclohexane or paraffins, for example petroleum fractions, mineral and vegetable oils, alcohols, such as butanol or glycol as well as their ethers and esters, ketones, such as acetone, methyl ethyl ketone, methyl isobutyl ketone or cyclohexanone; strongly polar solvents, such as dimethylformamide and dimethylsulphoxide.
  • aromatic hydrocarbons such as xylene, toluene or alkyl naphthalenes
  • chlorinated aromatic hydrocarbons and chlorinated aliphatic hydrocarbons such as chlorobenzenes, methylene chloride
  • solvents are agriculturally unacceptable, and need to be used in low or high concentrations to produce formulations of desired strength, which can be diluted and applied to the target areas to control pest effect. Selection and use of the solvent is based on the solubility criteria for active ingredients which sometimes require a single solvent or a combination of solvents as per the type and strength of the formulation product.
  • WO 9007275 discloses a dry herbicidal composition
  • a dry herbicidal composition comprising a water soluble salt of N-phosphonomethylglycine as a water dispersible granule, water soluble granule, water dispersible powder or water soluble powder.
  • the composition comprises a water soluble salt of N-phosphonomethylglycine and additionally one or more liquid surfactants.
  • This invention requires a preparation of herbicidal water soluble salt during the process from its acid derivative (which is solid in physical form) or a water soluble salt (in solid ' physical form) as one of the main ingredients.
  • Japanese patent 2003095810 discloses the wettable granules comprising liquid pesticidal active ingredient, solvent, emulsifier, dispersion agent and surfactant. This invention requires the use of solvent so that the active ingredient gets uniformly distributed over the inert ingredients.
  • prior art EP127773 discloses tablet preparation of a pesticidal composition comprising a pesticide , an emulsifier or dispersing agent for the pesticide and a self disintegrating agent capable of effervescing or swelling on being contacted with water.
  • the pesticide disclosed is a synthetic pyrethroid from 1-20% by weight.
  • This invention requires a self disintegrating agent which is capable of effervescing or swelling on being contacted with water.
  • Methylene dichloride is used as a solvent for the active ingredient and the simple mixing process is done to mix a solution of above active ingredient and other ingredients comprising emulsifier or dispersing agent, lubricants, surfactants and antifoaming agents. Then the granule formation is done followed by tablet formation.
  • Granules may also be prepared by coating a core granule with an absorbent coating of filler particles. A liquid active material may then be loaded onto the surface layer of the granules.
  • Such a process is disclosed in NZ Patent 154,193 where the objective was to produce granules with reduced absorptive properties compared to granules prepared from minerals such as attapulgite.
  • these granules are designed for direct application to soil, pastures or other locus and as they have cores of particle size approximately 250 ⁇ m they would not be suitable for use as WG as the granule would not pass through the spray nozzle.
  • the basic method of preparing granules involves a preliminary step of forming a wettable powder by blending the ingredients and milling them to provide the desired particle size.
  • the wettable powder is then subsequently formed into granules by a range of techniques including agglomeration, spray drying, or other means such as pan granulation.
  • the prior art teaches maximum of 25 EC and 25 WP for actives like Permethrin but no DF formulations exist in the market.
  • the present invention takes care of all these problems of dry WP, solid/granular, tablet/pellets formulations given in prior art and provides for higher concentrations of liquid actives for DF formulations.
  • Silica and kaolin are traditionally known as inert fillers while the block copolymer of ethylene oxide and propylene oxide is traditionally known for its use as a surfactant. Surprisingly it was found that when these were used in a definite ratio they imparted properties of good suspensibility and dispersibility to the formulation and also enabled in formulating high concentrations of the liquid active ingredient into free-flowing granular form.
  • the solid compositions of the proposed invention have excellent storage stability, dispersibility and suspensibility even after comprising high concentrations of pesticides from pyrethroid class.
  • the inventors of the present invention have additionally discovered the surprising effect of the synergistic action of the combined use of inert ingredients silica and kaolin which normally function only as fillers along with block copolymer of ethylene oxide and propylene oxide which normally functions only as a surfactant.
  • inert ingredients silica and kaolin which normally function only as fillers along with block copolymer of ethylene oxide and propylene oxide which normally functions only as a surfactant.
  • the main objective of the proposed invention is to provide a non dusty, free flowing, storage stable solid composition devoid of the draw backs of the hitherto known composition.
  • Another objective of the proposed invention is to provide non dusty, free flowing, storage stable solid composition having the properties of storage stability, excellent dispersibility and suspensibility.
  • Yet another objective of the proposed invention is to provide a non dusty, free flowing, storage stable solid composition
  • a pesticide from pyrethroid class like cypermethrin, fenvalerate, permethrin, alphacypermethrin, betacypermethrin, zetacypermethrin, deltamethrin, cyfluthrin, bifenthrin, lambda-cyhalothrin, and/or bioresmethrin.
  • Yet another objective of the proposed invention is to provide non dusty, free flowing, storage stable solid composition having the properties of excellent dispersibility and suspensibility using at least a liquid surfactant selected from polyoxyethlene alkyl ether group.
  • Another objective of the proposed invention is to provide non dusty, free flowing, storage stable solid composition having the properties of excellent dispersibility and suspensibility in solid form preferably in water dispersible granular form.
  • Yet another objective of the proposed invention is to provide a process for the preparation of non dusty, free flowing, storage stable solid composition which is a relatively inexpensive and environmentally safe.
  • Yet another objective of the proposed invention is to provide a process for the preparation of non dusty, free flowing, storage stable solid composition in water dispersible granular form which are not prone to dust generation while filling in bags and transportation, thereby avoiding polluting the environment.
  • Another objective of the proposed invention is to provide a process for the preparation of non dusty, free flowing, storage stable solid composition in water dispersible granular form by using the liquid pesticide.
  • Yet another objective of the proposed invention is to provide a process for the preparation of non dusty, free flowing, storage stable solid composition in water dispersible granular form by using at least a liquid pesticide and at least one liquid surfactant.
  • Yet another objective of the proposed invention is to provide a process for the preparation of non dusty, free flowing, storage stable solid composition without using any solvents.
  • the above mentioned objectives of the proposed invention have been achieved by our sustained R & D due to our finding that in solid composition comprising pyrethroids, the use of liquid surfactants selected from polyoxyethlene alkyl ether group and when this composition is coated on a mixture of Kaolin and precipitated silica as an inert filler in selected ratio provides good dispersibility and suspensibility to the resulting solid composition.
  • kaolin which normally acts as inert filler, acts as a carrier in the composition of the present invention due to adsorption process.
  • silica which is normally used as an adsorbent, functions as an anticaking agent.
  • the proposed invention provides a non dusty, free flowing, storage stable solid composition which comprises a mixture of kaolin and precipitated silica having a coating of a composition comprising at least one pesticide selected from pyrethroid class like cypermethrin, fenvalerate, permethrin, alphacypermethrin, betacypermethrin, zetacypermethrin, deltamethrin, cyfluthrin, bifenthrin, lambda-cyhalothrin, and/or bioresmethrin and at least one liquid surfactant selected from polyoxyethlene alkyl ether group.
  • a pesticide selected from pyrethroid class like cypermethrin, fenvalerate, permethrin, alphacypermethrin, betacypermethrin, zetacypermethrin, deltamethrin, cyfluthrin, bif
  • a process for the preparation of a non dusty, free flowing, storage stable solid composition which comprises:
  • step (iii) adding the liquid mixture obtained in step (i) to a mixing vessel containing the powder prepared described in step (ii);
  • step (iv) mixing thoroughly the ingredients of step (iii);
  • step (v) granulating the resulting mixture obtained in step (iv);
  • the present invention is broadly related to free-flowing solid compositions of high concentrations of liquid pyrethroid pesticides with good suspensibility and dispersability properties. These properties are achieved by the combined use of inert ingredients silica and kaolin along with polyoxyethlene alkyl ether or block copolymer of ethylene oxide and propylene oxide. Silica and kaolin are traditionally known as fillers and block copolymer of ethylene oxide and propylene oxide is traditionally known for its use as a surfactant for liquid compositions.
  • Experiments were conducted to select and evaluate the inert fillers of at least some oil absorption value of 75 to make the dry flowable particulates of upto 50% liquid active. Inert clay kaolin and silica were evaluated individually for their effect on granule formation.
  • Kaolin has a liquid holding capacity (LHC) or oil absorbtion of 10-20 %;
  • Table 1 Effect of various concentrations of inert clay kaolin on granulation of various concentrations of active ingredient.
  • Clay minerals of the montmorillonite group based on a three layer structure comprising two tetragonal layers of SiO 4 sandwiching an octagonal layer of AIO 6 between them, and a plurality of such basic three-layer structures were also evaluated.
  • Montmorillonite has a liquid holding capacity (LHC) or oil absorption of 30 - 70 %.
  • Table 3 Effect of various concentrations of inert clay montmorillonite on granulation of various concentration of active ingredients.
  • Bentonite is a naturally occurring, white calcium clay. Due to its thixotropic properties, bentonite functions as a thickening and/or suspension agent in water and solvent paints.
  • Table 4 Effect of various concentrations of inert clay Bentonite on granulation of various concentration of active ingredients.
  • Table 8 Effect of traditional liquid surfactants on dispersibility and suspensibility of the DF composition.
  • Table 9 Effect of various concentrations of EO/PO on granule quality.
  • the working range of EO /PO surfactants was found to be optimal between 1.5 to 3.75 %. Within this range good emulsification of the liquid active ingredient was observed. To further improve the dispersibility and suspensibility of silica and kaolin, styrene acrylic co-polymer was considered.
  • Table 10 Effect of various concentrations of Styrene acrylic copolymer on granule quality.
  • Styrene acrylic copolymer 5 to 10% was found to give good dispersibility and suspensibility for the optimal ratio of silica and kaolin.
  • a combination of EO/PO with styrene copolymer was studied for further improvement of the granule dispersibility and suspensibility.
  • Table 11 Effect of a combination of various concentrations of EO/PO and Styrene acrylic copolymer.
  • Polyoxyethlene alkyl ether the block copolymer of ethylene oxide and propylene oxide is a surfactant having a comparable hydrophilic chains length than those of most other surfactants and they are flexible. They bind water avidly by hydrogen bond acceptor interactions with ether-linked oxygen. These long, strongly hydrated flexible chains are relatively incompressible and form a barrier to hydrophobic surfaces approaching one another.
  • non- ionic and anionic emulsifiers such as polyoxyethylene-fatty acid esters, polyoxyethylene-fatty alcohol ethers, for example alkylaryl polyglycol ethers, alkylsulphonates, alkylarylsulphonates, alkylsulphates, arylsulphonates , their hydrolysis products & salts.
  • polyoxyethlene alkyl ether in this case helped to provide a solid composition with at least 60 % dispersibility and suspensibility despite high concentrations of viscous liquid pesticide.
  • a mixture prepared by adding active ingredient with atleast one polyoxyethylene alkyl ether surfactant helps to cover the treated surface area uniformly.
  • wetting agent is meant a compound which permits the granule to rapidly wet into the water, and, more precisely, a compound which, when mixed in selected proportions with agriculturally active compounds, in the form of granules, give a mixture which has a wettability time of less than 2 minutes.
  • This wetting agent can be an ionic or non-ionic agent or a mixture of such surface-active agents.
  • alkylarylsulphonate-type salts in particular the alkali metal alkylnaphthalene sulphonates
  • the salts of polycarboxylic acids polycondensates of ethylene oxide with fatty alcohols or with fatty acids or with fatty amines, or substituted phenols (in particular alkylphenols or arylphenols), and salts of esters of sulphosuccinic acids.
  • dispersing agent a compound which ensures that the particles remain suspended in the application mixture and which allows rapid disintegration of the granule in the water. More precisely, by dispersing agent is meant a compound which, when intimately mixed in selected proportions with agriculturally active compounds, in the form of granules, gives a mixture which has a suspensibility of more than 50%.
  • the dispersing agent can be an ionic or non-ionic agent or a mixture of such surface-active agents.
  • arylsulphonate-type polymers in particular the alkali metal polynaphthalenesulphonates obtained by condensation of (alkyl)arylsulphonates with formaldehyde, the lignosulphonates, the polyphenylsulphonates, salts of polyacrylic acids, salts of lignosulphonic acids, salts of phenolsulphonic acids or naphthalenesulphonic acids, taurine derivatives (in particular alkyltaurates), phosphoric esters of alcohols or of polycondensates of ethylene oxide and phenols, esters of fatty acids and polyols, and the derivatives of the preceding compounds which have sulphate, sulphonate and phosphate functions.
  • binder refers to all binders which are suitable for solid compositions such as in water-dispersible solid formulations.
  • the following are preferably suitable in this context: methylcellulose, sugars, dextrin, starch, alginates, glycols, polyvinyl pyrrolidone, ligninsulphonate, gum arabic, polyvinyl alcohol and polyvinyl acetate, water, or a solution containing dissolved wetting and dispersing agents.
  • inert fillers refer to a solid organic or inorganic material, natural or synthetic, with which the active substance is combined so as to facilitate the specific application of the granulated product. This filler is therefore generally inert and acceptable.
  • the filler can be selected for example from amongst clay, diatomaceous earth, kaolin clay, the natural or synthetic silicates, silica, precipitated silica, soluble or insoluble mineral salts, organic derivatives, and polysaccharide compounds such as starch, cellulose, aliginates, soluble mineral salts, sugars and lactose or a combination thereof.
  • the inert fillers which can be used are hydrophilic fillers which have a disintegrating action, that is ' to say which facilitate the adsorption as well as absorption of active ingredient and also facilitate the dispersion and suspension of the granule according to the invention in the presence of water.
  • the product (first compound) may contain at least a second active compound of a type which differs from the first compound, which has the aim of widening the spectrum of the first one.
  • the first and second compound may be a contact pesticide, which act by contact with the plants/pests.
  • This second agent may be present in the solid composition prepared by the process of the proposed invention in an amount between 0.1 to 40.0 %.
  • the first agricultural compound may be present in quantities, preferably between 0.1 to 50.0 %, the other ingredients in the end product being the wetting agent, dispersing agent and inert fillers.
  • the granulated product may also contain 10.0 to 99.80 % of suitable additives, such as antifoams, sequestering agents, stabilizers, penetrating agents, adhesives, anti-caking agents, colorants, and others.
  • suitable additives such as antifoams, sequestering agents, stabilizers, penetrating agents, adhesives, anti-caking agents, colorants, and others.
  • the process of the proposed invention is generally carried out starting with the mixing of an active ingredient, with at least polyoxyethlene alkyl ether surfactants to obtain a liquid mixture. There after the preparation of the powders of wetting agent, dispersing agent, binder and inert fillers by mixing is done. This mixing of the powders may be done in suitable mixers.
  • adding of the liquid mixture is done over the powder prepared. After complete addition of the liquid mixture these ingredients are mixed thoroughly to obtain a homogenous powdery mixture.
  • This powdery mixture can also be considered as one of the forms of invented solid composition which is in the form of powder. If the granulated product is required then this is achieved by continuing the mixing for an additional time, after spraying was over. Thereafter granulation of the mixture is performed by using water as a granulating liquid. Then the fine particles are separated from oversized particles. If required, the fine and oversized particles are recycled and drying of the granules is done, as required, in a drier like equipment like Fluidized bed dryer to a moisture content below 2 % w/w. Again sieving of the dried granules is done by using vibratory sieve to finally remove any fine and or oversize granules. The fine and the oversize separated particles can be recycled to the granulator after drying and grinding to suitable particle size.
  • the powder taken in the container of the apparatus is mixed with granulating liquid, from 1 to 30%, preferably 5 to 15 % of the required quantities.
  • This moistened powder has the consistency of a non drifting dust.
  • This is further processed in the container with the addition of remaining quantity of the granulating liquid in such a way as to obtain the granulated product.
  • the granules prepared by the process according to the proposed invention are therefore concentrated products.
  • the granulated agricultural products which are prepared according to the process of the proposed invention which are diluted by the agriculturalists in containers which contain water for application. These diluted mixtures are usually applied at 5 to 1000 I/ha.
  • compositions of the present invention actually fall into the category of dispersible granules comprising an intrinsic combination of granule, surfactant/s, oil (the active ingredient which is in the form of a viscous liquid is considered as the oil which is emulsified) and the active ingredient which is adsorbed on the solid inert ingredient/s.
  • active ingredients used may be in the range of 0.1- 50% by weight of composition.
  • the solid composition has a long activity and quick-acting property with residual effectiveness and improvement in stickiness, fluidity and bulkiness, also from the view point of physical properties of the formulation.
  • composition was designed to test the effect of solid surfactants such as Sodium naphthalene formaldehyde condensate and Sodium naphthalene sulfonate on the performance of the granules.
  • Example 1 The composition of Example 1 which resulted in granules of sticky nature was modified to increase the quantity of silica to 46.01% to improve the flowability of the granules.
  • composition was modified to include organic solvents in the formulation..
  • the above composition was unable to provide the required degree of dispersibility and suspensibility to the granules.
  • composition A contained 1.75% of POE of alkyl ether containing alkyl phenol ethoxylate
  • Composition B contained 2.75% of POE of alkyl ether containing alkyl phenol ethoxylate
  • Composition C contained 3.75% of POE of alkyl ether containing alkyl phenol ethoxylate.
  • composition A and C showed reduced emulsification of permethrin.
  • Composition B showed optimal results and was considered as most appropriate for the composition.
  • Composition B was tested for required parameters the following results were observed:
  • compositions were designed and designated as A, B and C with variations in amounts of silica.
  • composition A with 5% silica resulted in slightly sticky granules having average suspensibility.
  • Composition C resulted in granules with good flowability but reduced suspensibility.
  • Composition B with 10% silica resulted in granules with very good flowability and suspensibility. The optimum concentration of 10 % was selected.
  • the resultant granules were sticky in nature with reduced flowability and could not be further processed.
  • composition A contains 5% Styrene acrylic copolymer
  • composition B contains 8% Styrene acrylic copolymer
  • composition C contains 13% Styrene acrylic copolymer.
  • composition A there was a drop in suspensibility.
  • Composition B had ideal suspensibility.
  • composition C excess foaming was observed. It was concluded that 8% Styrene acrylic copolymer was optimal for attaining desirable suspensibility of the formulation.
  • Styrene acrylic copolymer (8.00 %w/w), Sodium naphthalene sulfonate (5.00 %w/w), pre ground Kaolin (46.01 %w/w), Homopolymer of Vinylpyrrolidone (0.25 %w/w), Precipitated Silica (10.00 %w/w) are transferred in appropriate blender having spray arrangement. The mixture was blended for 10 min. along with the spraying of the liquid mixture of step I over it. The blending was continued for further 10 min. after spraying was completed.
  • step Il Using appropriate granulator and mechanized water spray system, the product of step Il was granulated to get non-dusty, free flowing, storage stable granules.
  • the ingredients used are given below in table 1.
  • the desired sized wet/ conditioned granules were dried using equipment like fluidized bed drier to moisture content below 2% w/w.
  • the dried granules were sieved by using vibratory sieve, the fines and oversized separated were recycled in granulator after drying and grinding to suitable particle size.
  • the representative composite sample of dried and required dust free granules was analyzed.
  • the characteristic outcome of the employment of the process of the proposed invention is the dispersing and wetting of almost 100% of the particles with a minimum of water.
  • Wettability time of less than 2 minutes, preferably less than 1 minute; ii) Dispersibility of more than 60 %, preferably more than 70 %; iii) Suspensibility of more than 60 %, preferably more than 75%; iv) Dustiness less than 1 % w/w, preferably less than 0.6 % w/w.
  • the drying temperature is also less, in-between 50 to 60° C 1 leading to energy savings as compared to conventional processes.
  • the present granular pesticidal formulation is used for controlling pests.
  • the pesticidally active compound is an insecticidal compound, they are preferably used for vegetables or fruit trees.
  • the present granular pesticidal formulation is used as water dispersible granules, to be precise; the present granular pesticidal formulation is diluted with water and then applied to crop, soil or the like with a sprayer or the like.

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  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Toxicology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

L'invention concerne une composition pesticide solide granulaire pouvant être dispersée dans l'eau, comprenant jusqu'à 50% d'au moins un pesticide de type pyréthroïde, plus particulièrement un insecticide pyréthroïde liquide hautement visqueux, la perméthrine, présentant d'excellentes propriétés de dispersion et de suspension, ainsi que le procédé de préparation de ladite composition. L'invention concerne également les propriétés améliorées de stabilité dans des conditions de stockage, de dispersion et de suspension de ladite composition granulaire.
PCT/IN2008/000271 2007-04-26 2008-04-28 Composition solide non poussiéreuse à écoulement libre, stable dans des conditions de stockage, et procédé de préparation WO2009007999A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN802/MUM/2007 2007-04-26
IN802MU2007 2007-04-26

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WO2009007999A2 true WO2009007999A2 (fr) 2009-01-15
WO2009007999A3 WO2009007999A3 (fr) 2010-03-11

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010095151A2 (fr) 2009-02-20 2010-08-26 Deepak Pranjivandas Shah Composition granulaire hydro-dispersible
WO2013127790A3 (fr) * 2012-03-02 2013-12-19 Basf Se Granulé émulsionnable pouvant être obtenu en mélangeant une émulsion antiparasitaire avec un agent dispersant solide et en extrudant la pâte résultante
CN111405848A (zh) * 2017-05-25 2020-07-10 Upl有限公司 稳定的农用化学品组合物及其方法
CN114794139A (zh) * 2022-05-16 2022-07-29 西南大学 一种胺菊酯和呋虫胺的杀虫水分散粒剂及其制备方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996036226A1 (fr) * 1995-05-15 1996-11-21 Rhone-Poulenc Chimie Granule dispersable dans l'eau de matiere active phytosanitaire liquide ou a bas point de fusion
US5705193A (en) * 1993-12-22 1998-01-06 Roussel Uclaf Method for preparing granules containing one or more active principles
WO2005039288A2 (fr) * 2003-10-22 2005-05-06 United Phosphorus, Ltd. Composition insecticide a activite synergique renforcee

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5705193A (en) * 1993-12-22 1998-01-06 Roussel Uclaf Method for preparing granules containing one or more active principles
WO1996036226A1 (fr) * 1995-05-15 1996-11-21 Rhone-Poulenc Chimie Granule dispersable dans l'eau de matiere active phytosanitaire liquide ou a bas point de fusion
WO2005039288A2 (fr) * 2003-10-22 2005-05-06 United Phosphorus, Ltd. Composition insecticide a activite synergique renforcee

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010095151A2 (fr) 2009-02-20 2010-08-26 Deepak Pranjivandas Shah Composition granulaire hydro-dispersible
WO2013127790A3 (fr) * 2012-03-02 2013-12-19 Basf Se Granulé émulsionnable pouvant être obtenu en mélangeant une émulsion antiparasitaire avec un agent dispersant solide et en extrudant la pâte résultante
EP3117708A1 (fr) * 2012-03-02 2017-01-18 Basf Se Granule émulsifiable pouvant être obtenue par mélange d'une émulsion pesticide avec dispersant solide et extrusion de la pâte résultante
EA030778B1 (ru) * 2012-03-02 2018-09-28 Басф Се Способ изготовления эмульгирующихся гранул посредством смешивания пестицидной эмульсии с твёрдым диспергирующим веществом и экструдирования полученной пасты
US10383327B2 (en) 2012-03-02 2019-08-20 Basf Se Emulsifiable granule obtainable by mixing an pesticidal emulsion with solid dispersant and extruding the resulting paste
CN111405848A (zh) * 2017-05-25 2020-07-10 Upl有限公司 稳定的农用化学品组合物及其方法
EP3629733A4 (fr) * 2017-05-25 2021-03-10 UPL Ltd Composition agrochimique stable et procédé correspondant
CN114794139A (zh) * 2022-05-16 2022-07-29 西南大学 一种胺菊酯和呋虫胺的杀虫水分散粒剂及其制备方法

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