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WO2008136058A1 - Sample plate for laser desorption ionization and mass spectrometer utilizing the sample plate - Google Patents

Sample plate for laser desorption ionization and mass spectrometer utilizing the sample plate Download PDF

Info

Publication number
WO2008136058A1
WO2008136058A1 PCT/JP2007/000456 JP2007000456W WO2008136058A1 WO 2008136058 A1 WO2008136058 A1 WO 2008136058A1 JP 2007000456 W JP2007000456 W JP 2007000456W WO 2008136058 A1 WO2008136058 A1 WO 2008136058A1
Authority
WO
WIPO (PCT)
Prior art keywords
sample plate
layer
laser desorption
pores
desorption ionization
Prior art date
Application number
PCT/JP2007/000456
Other languages
French (fr)
Japanese (ja)
Inventor
Kuniaki Kanamaru
Original Assignee
Shimadzu Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shimadzu Corporation filed Critical Shimadzu Corporation
Priority to PCT/JP2007/000456 priority Critical patent/WO2008136058A1/en
Publication of WO2008136058A1 publication Critical patent/WO2008136058A1/en

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0409—Sample holders or containers
    • H01J49/0418—Sample holders or containers for laser desorption, e.g. matrix-assisted laser desorption/ionisation [MALDI] plates or surface enhanced laser desorption/ionisation [SELDI] plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/028—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having reaction cells in the form of microtitration plates

Landscapes

  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Electron Tubes For Measurement (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)

Abstract

Sample plate (20) for laser desorption ionization is obtained by superimposing Al2O3 layer (22) having a multiplicity of pores (23) of about 20 to 30 nm diameter as a heat insulation layer on Al plate substratum (21) and superimposing on the surface thereof bilayer metal thin film (24) composed of Ti layer (24a) and Pt layer (24b). As the combination of dissimilar metals Ti/Pt exerts high H+ addition catalyzing capability, high ionization efficiency can be attained even when pores (23) of large diameter as in the prior art are not provided. Accordingly, the duration of anodizing treatment at the forming of the Al2O3 layer (22) can be short, and no special treatment for forming of the pores (23) of large diameter is needed. Therefore, the production can be facilitated, and the cost can be reduced.
PCT/JP2007/000456 2007-04-25 2007-04-25 Sample plate for laser desorption ionization and mass spectrometer utilizing the sample plate WO2008136058A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/JP2007/000456 WO2008136058A1 (en) 2007-04-25 2007-04-25 Sample plate for laser desorption ionization and mass spectrometer utilizing the sample plate

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2007/000456 WO2008136058A1 (en) 2007-04-25 2007-04-25 Sample plate for laser desorption ionization and mass spectrometer utilizing the sample plate

Publications (1)

Publication Number Publication Date
WO2008136058A1 true WO2008136058A1 (en) 2008-11-13

Family

ID=39943183

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2007/000456 WO2008136058A1 (en) 2007-04-25 2007-04-25 Sample plate for laser desorption ionization and mass spectrometer utilizing the sample plate

Country Status (1)

Country Link
WO (1) WO2008136058A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109585254A (en) * 2018-11-15 2019-04-05 复旦大学 A kind of Matrix Assisted Laser Desorption mass spectrum high-volume sampling device
EP3474310A1 (en) 2017-10-18 2019-04-24 Shimadzu Corporation Information management device for mass spectrometer

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003536073A (en) * 2000-06-05 2003-12-02 カイロン コーポレイション Microarrays for performing proteomics analysis
WO2006046697A1 (en) * 2004-10-29 2006-05-04 Japan Science And Technology Agency Substrate for maldi-tof ms and mass spectrometry method using the same

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003536073A (en) * 2000-06-05 2003-12-02 カイロン コーポレイション Microarrays for performing proteomics analysis
WO2006046697A1 (en) * 2004-10-29 2006-05-04 Japan Science And Technology Agency Substrate for maldi-tof ms and mass spectrometry method using the same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SHOJI OKUNO: "Requirements for Laser-Induced Desortion/Ionization on Submicrometer Structures", ANALYTICAL CHEMISTRY, vol. 77, no. 16, 2005, pages 5364 - 5369, XP003012113 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3474310A1 (en) 2017-10-18 2019-04-24 Shimadzu Corporation Information management device for mass spectrometer
US12176197B2 (en) 2017-10-18 2024-12-24 Shimadzu Corporation Information management device for mass spectrometer
CN109585254A (en) * 2018-11-15 2019-04-05 复旦大学 A kind of Matrix Assisted Laser Desorption mass spectrum high-volume sampling device

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