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WO2008097924A3 - Compositions pharmaceutiques comprenant des analogues du dextrométhorphane pour le traitement de troubles neurologiques - Google Patents

Compositions pharmaceutiques comprenant des analogues du dextrométhorphane pour le traitement de troubles neurologiques Download PDF

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Publication number
WO2008097924A3
WO2008097924A3 PCT/US2008/052949 US2008052949W WO2008097924A3 WO 2008097924 A3 WO2008097924 A3 WO 2008097924A3 US 2008052949 W US2008052949 W US 2008052949W WO 2008097924 A3 WO2008097924 A3 WO 2008097924A3
Authority
WO
WIPO (PCT)
Prior art keywords
pharmaceutical compositions
neurological disorders
treatment
dextromethorphan analogs
analogs
Prior art date
Application number
PCT/US2008/052949
Other languages
English (en)
Other versions
WO2008097924A2 (fr
Inventor
Jagadish Sircar
Kc Sunil Kumar
Original Assignee
Avanir Pharmaceuticals
Jagadish Sircar
Kc Sunil Kumar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avanir Pharmaceuticals, Jagadish Sircar, Kc Sunil Kumar filed Critical Avanir Pharmaceuticals
Publication of WO2008097924A2 publication Critical patent/WO2008097924A2/fr
Publication of WO2008097924A3 publication Critical patent/WO2008097924A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'invention concerne des compositions pharmaceutiques et des procédés servant à traiter des troubles neurologiques en administrant celles-ci. Les compositions comprennent des analogues du dextrométhorphane.
PCT/US2008/052949 2007-02-05 2008-02-04 Compositions pharmaceutiques comprenant des analogues du dextrométhorphane pour le traitement de troubles neurologiques WO2008097924A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89947207P 2007-02-05 2007-02-05
US60/899,472 2007-02-05

Publications (2)

Publication Number Publication Date
WO2008097924A2 WO2008097924A2 (fr) 2008-08-14
WO2008097924A3 true WO2008097924A3 (fr) 2008-11-20

Family

ID=39682370

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/052949 WO2008097924A2 (fr) 2007-02-05 2008-02-04 Compositions pharmaceutiques comprenant des analogues du dextrométhorphane pour le traitement de troubles neurologiques

Country Status (1)

Country Link
WO (1) WO2008097924A2 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2345653T3 (da) 2007-05-01 2013-04-08 Concert Pharmaceuticals Inc Morphinanforbindelser
AU2016253556B2 (en) * 2007-05-01 2018-07-05 Sun Pharmaceutical Industries, Inc. Morphinan compounds
SI3825306T1 (sl) 2007-05-01 2023-10-30 Sun Pharmaceutical Industries, Inc. Morfinanske spojine
US20120053169A1 (en) * 2008-10-30 2012-03-01 Amanda Thomas Combination of morphinan compounds and antidepressant for the treatment of pseudobulbar affect, neurological diseases, intractable and chronic pain and brain injury
PL2397158T3 (pl) * 2008-10-30 2016-09-30 Skojarzone podawanie związków morfinanów oraz leków przeciwdepresyjnych w leczeniu nietrzymania afektu
WO2011017319A1 (fr) * 2009-08-03 2011-02-10 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Méthodes de traitement de troubles associés à la polymérisation d'une protéine
US8809617B2 (en) 2009-11-05 2014-08-19 The University of Pittsburgh—Of the Commonwealth System of Higher Education Automated high-content live animal drug screening using C. elegans
US9072772B2 (en) 2009-11-05 2015-07-07 University of Pittsburgh—of the Commonwealth System of Higher Education Methods of treating disorders associated with protein aggregation
CN106421792A (zh) 2012-02-06 2017-02-22 创新医学概念有限责任公司 包含抗病毒成分和cox‑2抑制剂成分组合的药物组合物及用于药物组合疗法的药盒
RU2020116666A (ru) * 2014-09-14 2020-07-31 Аванир Фармасьютикалз, Инк. Фармацевтические композиции, содержащие декстрометорфановое соединение и хинидин для лечения возбуждения при деменции
PL3383851T3 (pl) * 2015-12-03 2022-01-10 Heinrich-Heine-Universität Düsseldorf Pochodne dekstrorfanu o stłumionej nerwowej aktywności ośrodkowej
WO2017117347A1 (fr) * 2015-12-30 2017-07-06 Markovitz M D Paul Méthode de traitement de la schizophrénie
EP4499223A1 (fr) * 2022-03-31 2025-02-05 Heinrich-Heine-Universität Düsseldorf Synthèse de morphinanes ayant une activité herg réduite et une liaison mop
CN117720633B (zh) * 2024-02-08 2024-05-14 鄂尔多斯市中心医院（内蒙古自治区超声影像研究所） 一种蜱的镇痛蛋白及其编码基因在镇痛中的应用

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NELSON KA ET AL.: "High-dose oral dextromethorphan versus placebo in painful diabetic neuropathy and postherpetic neuralgia", NEUROLOGY, vol. 48, 1997, pages 1212 - 1218, XP009154148 *

Also Published As

Publication number Publication date
WO2008097924A2 (fr) 2008-08-14

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