[go: up one dir, main page]

WO2008004224A3 - Synergistic compositions for crohn's disease and inflammatory gastrointestinal disorders - Google Patents

Synergistic compositions for crohn's disease and inflammatory gastrointestinal disorders Download PDF

Info

Publication number
WO2008004224A3
WO2008004224A3 PCT/IL2007/000828 IL2007000828W WO2008004224A3 WO 2008004224 A3 WO2008004224 A3 WO 2008004224A3 IL 2007000828 W IL2007000828 W IL 2007000828W WO 2008004224 A3 WO2008004224 A3 WO 2008004224A3
Authority
WO
WIPO (PCT)
Prior art keywords
disease
gastrointestinal disorders
crohn
synergistic compositions
inflammatory gastrointestinal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IL2007/000828
Other languages
French (fr)
Other versions
WO2008004224A2 (en
Inventor
Arie Levine
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of WO2008004224A2 publication Critical patent/WO2008004224A2/en
Anticipated expiration legal-status Critical
Publication of WO2008004224A3 publication Critical patent/WO2008004224A3/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to methods and synergistic compositions comprising a nitroimidazole antibiotic and a macrolide antibiotic, optionally in combination with polyphenolic compounds naturally contained in plant or fruit, for treatment of chronic inflammatory gastrointestinal disorders including Crohn's disease.
PCT/IL2007/000828 2006-07-03 2007-07-03 Synergistic compositions for crohn's disease and inflammatory gastrointestinal disorders Ceased WO2008004224A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81769106P 2006-07-03 2006-07-03
US60/817,691 2006-07-03

Publications (2)

Publication Number Publication Date
WO2008004224A2 WO2008004224A2 (en) 2008-01-10
WO2008004224A3 true WO2008004224A3 (en) 2009-04-09

Family

ID=38894986

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2007/000828 Ceased WO2008004224A2 (en) 2006-07-03 2007-07-03 Synergistic compositions for crohn's disease and inflammatory gastrointestinal disorders

Country Status (1)

Country Link
WO (1) WO2008004224A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108135982A (en) * 2015-06-16 2018-06-08 默多克儿童研究所 The method for treating Crohn disease

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008093148A2 (en) 2005-12-22 2008-08-07 Anaborex, Inc. Compositions and methods for prevention and treatment of cachexia
US7947579B2 (en) * 2006-02-13 2011-05-24 Stc.Unm Method of making dense, conformal, ultra-thin cap layers for nanoporous low-k ILD by plasma assisted atomic layer deposition
EP2135616B1 (en) * 2008-06-19 2016-05-04 Symrise AG Dried bilberries for influencing intestinal conditions
WO2012135702A1 (en) * 2011-04-01 2012-10-04 Ocean Spray Cranberries, Inc. Inflammation and immunity treatments
CN103142494B (en) * 2013-03-19 2018-06-26 河北凯盛医药科技有限公司 Ornidazole oral preparation and preparation method thereof
US20170165233A1 (en) * 2014-12-20 2017-06-15 John Malcolm Hall Gregg Antimicrobial drug synthesis and therapeutic compositions
EP3768262A4 (en) * 2018-03-23 2021-12-15 Thomas Julius Borody COMPOSITIONS AND METHODS OF TREATMENT INFLAMMATORY INTESTINAL DISEASES CAUSED BY FUSO BACTERIA OR RELATED DISEASES AND DISORDERS

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5599795A (en) * 1994-08-19 1997-02-04 Mccann; Michael Method for treatment of idiopathic inflammatory bowel disease (IIBD)
US6219997B1 (en) * 1996-07-01 2001-04-24 Astrazeneca Ab Blister pack
US6379651B1 (en) * 1995-02-07 2002-04-30 Josman Laboratories Oral-topical dosage forms for delivering antibacterials/antibiotics to oral cavity to eradicate H. pylori as a concomitant treatment for peptic ulcers and other gastro-intestinal diseases

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5599795A (en) * 1994-08-19 1997-02-04 Mccann; Michael Method for treatment of idiopathic inflammatory bowel disease (IIBD)
US6379651B1 (en) * 1995-02-07 2002-04-30 Josman Laboratories Oral-topical dosage forms for delivering antibacterials/antibiotics to oral cavity to eradicate H. pylori as a concomitant treatment for peptic ulcers and other gastro-intestinal diseases
US6219997B1 (en) * 1996-07-01 2001-04-24 Astrazeneca Ab Blister pack

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE MEDLINE accession no. STN Database accession no. 10749316 *
HULTEN ET AL: "Antibacterial Therapy for Crohn's disease: a review emphasizing therapy directed against mycobacteria", DIGESTIVE DISEASES AND SC, vol. 45, no. 3, March 2000 (2000-03-01), XP002394153, DOI: doi:10.1023/A:1005453409445 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108135982A (en) * 2015-06-16 2018-06-08 默多克儿童研究所 The method for treating Crohn disease

Also Published As

Publication number Publication date
WO2008004224A2 (en) 2008-01-10

Similar Documents

Publication Publication Date Title
WO2008004224A3 (en) Synergistic compositions for crohn's disease and inflammatory gastrointestinal disorders
WO2006102610A3 (en) Bicycloheteroaryl compounds as p2x7 modulators and uses thereof
WO2007109192A3 (en) Bicycloheteroaryl compounds as p2x7 modulators and uses thereof
WO2007109172A3 (en) Bicycloheteroaryl compounds as p2x7 modulators and uses thereof
WO2007109160A3 (en) Bicycloheteroaryl compounds as p2x7 modulators and uses thereof
WO2007109182A3 (en) Bicycloheteroaryl compounds as p2x7 modulators and uses thereof
WO2007109154A3 (en) Bicycloheteroaryl compounds as p2x7 modulators and uses thereof
IL227934A (en) Immunogenic composition comprising type 5 and/or 8 capsular polysaccharide or oligosaccharide from s. aureus and various aspects related thereto
WO2007109201A3 (en) Bicycloheteroaryl compounds as p2x7 modulators and uses thereof
IL250858B (en) A tetracycline compound, a pharmaceutical composition comprising the tetracycline compound, and the tetracycline compound or the pharmaceutical composition for treating a tetracycline responsive state
WO2008070268A3 (en) Pharmaceutical compositions
GB2443287B (en) Methods, compositions and formulations for the treatment of thyroid eye disease
WO2007146965A3 (en) Compounds for the treatment of periodontal disease
IL184312A0 (en) Herbal compositions for the treatment of diabetes and/or conditions associated therewith
WO2006096439A3 (en) Pharmaceutical compositions for the treatment and/or prevention of schizophrenia and related diseases
AU2005339139A8 (en) Pharmaceutical compositions and methods for treating or preventing oxalate-related disease
IL197768A0 (en) Immunisation method against the 4 dengue serotypes
IL230052A0 (en) Immunisation method against the 4 dengue serotypes
WO2007019251A3 (en) Sphingosine kinase inhibitors and methods of their use
WO2005091853A3 (en) Methods and compositions for treating il-13 related pathologies
ZA200800448B (en) Methods and compositions for the prevention and treatment of inflammatory disease
IL187565A0 (en) Compositions and methods for the treatment or prevention of chemoresistant neoplasia
IL189009A0 (en) Methods and compositions for the treatment of neuropathies and related disorders
WO2008047061A3 (en) Cosmetic oral and/or parenteral use of glucosamine optionally in combination with at least one polyphenol compound, and corresponding composition
WO2008132021A3 (en) Fungicide mixtures

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 07766858

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

NENP Non-entry into the national phase

Ref country code: RU

122 Ep: pct application non-entry in european phase

Ref document number: 07766858

Country of ref document: EP

Kind code of ref document: A2