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WO2007111993A3 - Polyamine analogs as therapeutic agents for skin diseases - Google Patents

Polyamine analogs as therapeutic agents for skin diseases Download PDF

Info

Publication number
WO2007111993A3
WO2007111993A3 PCT/US2007/007226 US2007007226W WO2007111993A3 WO 2007111993 A3 WO2007111993 A3 WO 2007111993A3 US 2007007226 W US2007007226 W US 2007007226W WO 2007111993 A3 WO2007111993 A3 WO 2007111993A3
Authority
WO
WIPO (PCT)
Prior art keywords
polyamine analogs
skin diseases
therapeutic agents
psoriasis
dermatitis
Prior art date
Application number
PCT/US2007/007226
Other languages
French (fr)
Other versions
WO2007111993A2 (en
Inventor
Lawrence J Marton
Randolph M Johnson
Original Assignee
Cellgate Inc
Lawrence J Marton
Randolph M Johnson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cellgate Inc, Lawrence J Marton, Randolph M Johnson filed Critical Cellgate Inc
Publication of WO2007111993A2 publication Critical patent/WO2007111993A2/en
Publication of WO2007111993A3 publication Critical patent/WO2007111993A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

This disclosure relates to methods of treating atopic dermatitis, contact dermatitis, psoriasis, and certain other skin diseases using polyamine analogs. Conformationally restricted polyamine analogs are particularly useful in treating atopic dermatitis, contact dermatitis, and psoriasis.
PCT/US2007/007226 2006-03-22 2007-03-22 Polyamine analogs as therapeutic agents for skin diseases WO2007111993A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78505106P 2006-03-22 2006-03-22
US60/785,051 2006-03-22

Publications (2)

Publication Number Publication Date
WO2007111993A2 WO2007111993A2 (en) 2007-10-04
WO2007111993A3 true WO2007111993A3 (en) 2008-02-28

Family

ID=38541675

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/007226 WO2007111993A2 (en) 2006-03-22 2007-03-22 Polyamine analogs as therapeutic agents for skin diseases

Country Status (1)

Country Link
WO (1) WO2007111993A2 (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103118692A (en) 2010-04-26 2013-05-22 Atyr医药公司 Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of cysteinyl-tRNA synthetase
CA2797362C (en) 2010-04-27 2020-12-08 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of isoleucyl trna synthetases
US8993723B2 (en) 2010-04-28 2015-03-31 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of alanyl-tRNA synthetases
CN103097523B (en) 2010-04-29 2016-09-28 Atyr医药公司 The innovation for the treatment of, diagnosis and the antibody compositions relevant to the protein fragments of Asparaginyl-tRNA synthetase finds
WO2011139907A2 (en) 2010-04-29 2011-11-10 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of valyl trna synthetases
CN103140233B (en) 2010-05-03 2017-04-05 Atyr 医药公司 Treatment, diagnosis and the discovery of antibody compositions related to the protein fragments of methionyl-tRNA synthetase
US8961961B2 (en) 2010-05-03 2015-02-24 a Tyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related protein fragments of arginyl-tRNA synthetases
CA2797977C (en) 2010-05-03 2019-08-20 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-alpha-trna synthetases
EP2566499B1 (en) 2010-05-04 2017-01-25 aTyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of p38 multi-trna synthetase complex
CN103200953B (en) 2010-05-14 2017-02-15 Atyr 医药公司 Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-beta-trna synthetases
JP6046607B2 (en) 2010-05-27 2016-12-21 エータイアー ファーマ, インコーポレイテッド Innovative discovery of therapeutic, diagnostic and antibody compositions related to protein fragments of glutaminyl tRNA synthetase
WO2011153277A2 (en) 2010-06-01 2011-12-08 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of lysyl-trna synthetases
EP2593125B1 (en) 2010-07-12 2017-11-01 aTyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-trna synthetases
US9029506B2 (en) 2010-08-25 2015-05-12 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of tyrosyl-tRNA synthetases
US8691750B2 (en) 2011-05-17 2014-04-08 Axolabs Gmbh Lipids and compositions for intracellular delivery of biologically active compounds
US10815276B2 (en) 2014-05-21 2020-10-27 Entrada Therapeutics, Inc. Cell penetrating peptides and methods of making and using thereof
CN106852146B (en) 2014-05-21 2021-08-13 恩特拉达治疗学股份有限公司 Cell penetrating peptides and methods of making and using the same
EP3185880B1 (en) 2014-08-27 2020-02-12 Ohio State Innovation Foundation Improved peptidyl calcineurin inhibitors
CA3078504A1 (en) 2017-10-04 2019-04-11 Ohio State Innovation Foundation Bicyclic peptidyl inhibitors
WO2019148194A2 (en) 2018-01-29 2019-08-01 Ohio State Innovation Foundation Peptidyl inhibitors of calcineurin-nfat interaction
WO2019165183A1 (en) 2018-02-22 2019-08-29 Entrada Therapeutics, Inc. Compositions and methods for treating mitochondrial neurogastrointestinal encephalopathy
US11987647B2 (en) 2018-05-09 2024-05-21 Ohio State Innovation Foundation Cyclic cell-penetrating peptides with one or more hydrophobic residues
KR102167755B1 (en) 2018-05-23 2020-10-19 주식회사 큐어바이오 Fragmented GRS polypeptide, mutants thereof and use thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4112067A (en) * 1977-02-17 1978-09-05 The Dow Chemical Company Method for treating poison ivy dermatitis using certain polyamines and polytertiaryamides
US4160819A (en) * 1972-12-27 1979-07-10 Cincinnati Milacron, Inc. Method of inhibiting skin irritation
US5507321A (en) * 1993-08-25 1996-04-16 Ykk Corporation Heald frame for weaving a slide fastener stringer
US6794545B1 (en) * 1999-04-30 2004-09-21 Slil Biomedical Corporation Conformationally restricted polyamine analogs as disease therapies

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4160819A (en) * 1972-12-27 1979-07-10 Cincinnati Milacron, Inc. Method of inhibiting skin irritation
US4112067A (en) * 1977-02-17 1978-09-05 The Dow Chemical Company Method for treating poison ivy dermatitis using certain polyamines and polytertiaryamides
US5507321A (en) * 1993-08-25 1996-04-16 Ykk Corporation Heald frame for weaving a slide fastener stringer
US6794545B1 (en) * 1999-04-30 2004-09-21 Slil Biomedical Corporation Conformationally restricted polyamine analogs as disease therapies

Also Published As

Publication number Publication date
WO2007111993A2 (en) 2007-10-04

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