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WO2007046122A3 - Ozonised oil, process for the preparation and use thereof in medical field - Google Patents

Ozonised oil, process for the preparation and use thereof in medical field Download PDF

Info

Publication number
WO2007046122A3
WO2007046122A3 PCT/IT2006/000736 IT2006000736W WO2007046122A3 WO 2007046122 A3 WO2007046122 A3 WO 2007046122A3 IT 2006000736 W IT2006000736 W IT 2006000736W WO 2007046122 A3 WO2007046122 A3 WO 2007046122A3
Authority
WO
WIPO (PCT)
Prior art keywords
oil
ozone
ozonised
preparation
ozonised oil
Prior art date
Application number
PCT/IT2006/000736
Other languages
French (fr)
Other versions
WO2007046122A2 (en
Inventor
Orsola Modica
Maria Rosa Maietta
Gabriele Maietta
Original Assignee
Biopharma 3M S R L
Orsola Modica
Maria Rosa Maietta
Gabriele Maietta
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biopharma 3M S R L, Orsola Modica, Maria Rosa Maietta, Gabriele Maietta filed Critical Biopharma 3M S R L
Priority to EP06810027A priority Critical patent/EP1937635A2/en
Publication of WO2007046122A2 publication Critical patent/WO2007046122A2/en
Publication of WO2007046122A3 publication Critical patent/WO2007046122A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C3/00—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
    • C11C3/006—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by oxidation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J10/00—Chemical processes in general for reacting liquid with gaseous media other than in the presence of solid particles, or apparatus specially adapted therefor
    • B01J10/002—Chemical processes in general for reacting liquid with gaseous media other than in the presence of solid particles, or apparatus specially adapted therefor carried out in foam, aerosol or bubbles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J10/00—Chemical processes in general for reacting liquid with gaseous media other than in the presence of solid particles, or apparatus specially adapted therefor
    • B01J10/007—Chemical processes in general for reacting liquid with gaseous media other than in the presence of solid particles, or apparatus specially adapted therefor in the presence of catalytically active bodies, e.g. porous plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00049—Controlling or regulating processes
    • B01J2219/00051—Controlling the temperature
    • B01J2219/00054—Controlling or regulating the heat exchange system
    • B01J2219/00056—Controlling or regulating the heat exchange system involving measured parameters
    • B01J2219/00058—Temperature measurement
    • B01J2219/00063—Temperature measurement of the reactants
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L5/00—Gas handling apparatus
    • B01L5/04—Gas washing apparatus, e.g. by bubbling

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Wood Science & Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fats And Perfumes (AREA)

Abstract

The invention relates to a process for the preparation of ozonised oil including the following steps: a) evolvement of ozone anion radical by heterogenous catalysis carried out by means of ozone gas licking a suitable electron donor catalyst characterised in that the redox potential thereof is lower than that of ozone; b) contacting the ozone anion radical with an oil comprising unsaturated fatty acids for the formation of ozonides avoiding the contact between the oil and catalyst; c) verification of the reaction end when temperature constant values are obtained; d) stabilisation of the ozonised oil produced at the end of step c) by means of reaction with an suitable ox-red system resulting in the peroxide formation. Further the invention relates to ozonised oil obtainable using the process and uses thereof in medical, veterinary and cosmetic fields.
PCT/IT2006/000736 2005-10-17 2006-10-16 Ozonised oil, process for the preparation and use thereof in medical field WO2007046122A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP06810027A EP1937635A2 (en) 2005-10-17 2006-10-16 Ozonised oil, process for the preparation and use thereof in medical field

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITRM2005A000514 2005-10-17
ITRM20050514 ITRM20050514A1 (en) 2005-10-17 2005-10-17 OZONIZED OIL, HIGH-STABILITY ACTIVE INGREDIENT BASED ON PEROXIDES USABLE FOR MEDICAL THERAPEUTIC APPLICATIONS AND FOR SIMILAR DOMICILE TREATMENTS TO THOSE OF OZONOTHERAPY, WITHOUT THE USE OF OZONE GASSOUS.

Publications (2)

Publication Number Publication Date
WO2007046122A2 WO2007046122A2 (en) 2007-04-26
WO2007046122A3 true WO2007046122A3 (en) 2007-06-14

Family

ID=37806717

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IT2006/000736 WO2007046122A2 (en) 2005-10-17 2006-10-16 Ozonised oil, process for the preparation and use thereof in medical field

Country Status (3)

Country Link
EP (1) EP1937635A2 (en)
IT (1) ITRM20050514A1 (en)
WO (1) WO2007046122A2 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602006016627D1 (en) 2006-12-15 2010-10-14 Sanipan S R L Device for the topical application of medical ozone for the treatment of diseases of the oral cavity
RU2424816C2 (en) * 2008-03-17 2011-07-27 Государственное образовательное учреждение высшего профессионального образования "Нижегородская Государственная Медицинская академия" Росздрава (ГОУ ВПО НижГМА Росздрава) Method of post-operation monitoring of patients after radiosurgical treatment of tumour-like lesions and benign neoplasms of oral cavity mucosa
CN102245176B (en) 2008-10-31 2015-05-27 脂质医药有限公司 Fatty acids for use as a medicament
ITFI20090118A1 (en) * 2009-05-27 2010-11-27 Italmed S R L MIXED COMPOUNDS OF VEGETABLE ORIGIN WITH ANTISEPTIC ACTIVITY.
ITMI20110354A1 (en) * 2011-03-07 2012-09-08 Neovalis S R L COMPOSITION BASED ON OZONIZED OIL FOR TOPICAL USE
ITMI20111045A1 (en) 2011-06-10 2012-12-11 Uni Del Salento PROCEDURE FOR THE OZONIZATION OF A VEGETABLE OIL.
DE102012007239A1 (en) * 2012-04-10 2013-10-10 Wolfgang Winkelmann A pharmaceutical composition containing an oxygenated unsaturated fatty acid and an organic solvent
KR101618055B1 (en) * 2014-03-20 2016-05-09 동명대학교산학협력단 How to make cosmetics using Ozone Ointment and BHA
IT201600078872A1 (en) * 2016-07-27 2018-01-27 Fb Vision S R L OIL AND DEVICE FOR HYGIENE OF THE EYE AND PERIOCULAR AREA
CN107028977B (en) * 2016-11-17 2020-08-11 湖北精耕生物工程有限公司 Ozonized oil complex and preparation method and application thereof
IT201700063112A1 (en) * 2017-06-08 2018-12-08 Project & Communications Ltd FORMULATION FOR ORAL USE INCLUDING OZONIZED OIL IN THE PREVENTION AND / OR TREATMENT OF SKIN LESIONS CAUSED BY EXPOSURE TO IONIZING RADIATION AND / OR CHEMOTHERAPY TREATMENT.
CN110403926B (en) * 2019-08-14 2022-11-08 中南大学湘雅三医院 Application of nano acidified fatty acid ester in preparation of medicine for preventing and treating contact dermatitis
JP2023504422A (en) 2019-11-29 2023-02-03 ドゥムタ Use of hydroperoxyalcohols and their derivatives as antimicrobial agents

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3504038A (en) * 1966-06-24 1970-03-31 Us Agriculture Ozonization of vegetable oils in an improved aqueous medium
EP0235528A1 (en) * 1986-03-01 1987-09-09 Dr. J. Hänsler GmbH Process for preparing stable ozonized oils from unsaturated vegetable oils
WO2000039025A1 (en) * 1998-12-28 2000-07-06 Daewoo Electronics Co., Ltd. Radical generating system
JP2000351985A (en) * 1999-06-11 2000-12-19 Nippon Ozon Kk Production of ozonized vegetable oil and apparatus for producing ozonized vegetable oil
WO2003050081A1 (en) * 2001-12-11 2003-06-19 Cambridge Biopolymers Limited Oil ozonolysis
US20050113441A1 (en) * 1999-11-25 2005-05-26 Moraleda Manuel-Antonia G. Composition that comprises ozonised oils and/or other natural and/or synthetic ozonised products, and use thereof in pharmaceutical, cosmetic, dietary or food supplement products, in the human and veterinary fields

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3504038A (en) * 1966-06-24 1970-03-31 Us Agriculture Ozonization of vegetable oils in an improved aqueous medium
EP0235528A1 (en) * 1986-03-01 1987-09-09 Dr. J. Hänsler GmbH Process for preparing stable ozonized oils from unsaturated vegetable oils
WO2000039025A1 (en) * 1998-12-28 2000-07-06 Daewoo Electronics Co., Ltd. Radical generating system
JP2000351985A (en) * 1999-06-11 2000-12-19 Nippon Ozon Kk Production of ozonized vegetable oil and apparatus for producing ozonized vegetable oil
US20050113441A1 (en) * 1999-11-25 2005-05-26 Moraleda Manuel-Antonia G. Composition that comprises ozonised oils and/or other natural and/or synthetic ozonised products, and use thereof in pharmaceutical, cosmetic, dietary or food supplement products, in the human and veterinary fields
WO2003050081A1 (en) * 2001-12-11 2003-06-19 Cambridge Biopolymers Limited Oil ozonolysis

Also Published As

Publication number Publication date
WO2007046122A2 (en) 2007-04-26
ITRM20050514A1 (en) 2007-04-18
EP1937635A2 (en) 2008-07-02

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