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WO2007046083A3 - Compositions for treatment of eye diseases - Google Patents

Compositions for treatment of eye diseases Download PDF

Info

Publication number
WO2007046083A3
WO2007046083A3 PCT/IL2006/001168 IL2006001168W WO2007046083A3 WO 2007046083 A3 WO2007046083 A3 WO 2007046083A3 IL 2006001168 W IL2006001168 W IL 2006001168W WO 2007046083 A3 WO2007046083 A3 WO 2007046083A3
Authority
WO
WIPO (PCT)
Prior art keywords
compositions
eye diseases
treatment
present
eye
Prior art date
Application number
PCT/IL2006/001168
Other languages
French (fr)
Other versions
WO2007046083A2 (en
Inventor
Yoav Sharoni
Joseph Levy
Yoram Sela
Zohar Nir
Original Assignee
Lycored Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lycored Ltd. filed Critical Lycored Ltd.
Priority to AU2006305546A priority Critical patent/AU2006305546A1/en
Priority to MX2008004981A priority patent/MX2008004981A/en
Priority to JP2008535182A priority patent/JP2009515821A/en
Priority to EP06796159A priority patent/EP1937240A2/en
Publication of WO2007046083A2 publication Critical patent/WO2007046083A2/en
Priority to IL190779A priority patent/IL190779A0/en
Publication of WO2007046083A3 publication Critical patent/WO2007046083A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/01—Hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/34—Copper; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention relates to pharmaceutical compositions comprising a mixture of carotenoids and adjuvants, which provides synergistic therapeutic potential. The compositions of the present invention, which can be administered orally or topically to the eye, are useful in preventing, attenuating or treating eye diseases such as age-related macular degeneration (AMD), glaucoma, diabetic retinopathy and cataracts.
PCT/IL2006/001168 2005-10-16 2006-10-05 Compositions for treatment of eye diseases WO2007046083A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
AU2006305546A AU2006305546A1 (en) 2005-10-16 2006-10-05 Compositions for treatment of eye diseases
MX2008004981A MX2008004981A (en) 2005-10-16 2006-10-05 Compositions for treatment of eye diseases.
JP2008535182A JP2009515821A (en) 2005-10-16 2006-10-05 Composition for treating eye diseases
EP06796159A EP1937240A2 (en) 2005-10-16 2006-10-05 Compositions for treatment of eye diseases
IL190779A IL190779A0 (en) 2005-10-16 2008-04-10 Compositions for treatment of eye diseases

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL17145205 2005-10-16
IL171452 2005-10-16

Publications (2)

Publication Number Publication Date
WO2007046083A2 WO2007046083A2 (en) 2007-04-26
WO2007046083A3 true WO2007046083A3 (en) 2011-05-19

Family

ID=37962894

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2006/001168 WO2007046083A2 (en) 2005-10-16 2006-10-05 Compositions for treatment of eye diseases

Country Status (7)

Country Link
EP (1) EP1937240A2 (en)
JP (1) JP2009515821A (en)
AU (1) AU2006305546A1 (en)
IL (1) IL190779A0 (en)
MX (1) MX2008004981A (en)
RU (1) RU2008119234A (en)
WO (1) WO2007046083A2 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006051529A1 (en) 2004-11-09 2006-05-18 The Cupron Corporation Methods and materials for skin care
EP2086318A4 (en) * 2006-10-10 2009-12-23 Burnham Inst Medical Research NEUROPROTEKTIVE COMPOSITIONS AND METHOD
DE202007012373U1 (en) * 2007-09-04 2009-01-08 Omnivision Gmbh Dietary supplements, sachets containing a dietary supplement and use of a dietary supplement
EP2352493B1 (en) * 2008-11-03 2013-12-11 Giuliani S.p.A. Therapeutic, dietary, or cosmetic use of compounds with specific anti-apoptotic activity toward caspase-3, and compositions containing these compounds
PL2381935T3 (en) * 2009-01-19 2016-11-30 Synergistic combinations of carotenoids and polyphenols
WO2011076869A1 (en) * 2009-12-22 2011-06-30 Aakerlund Hans-Erik Isolated green plant material
JP2011256118A (en) * 2010-06-07 2011-12-22 Kao Corp Il-8 and gm-csf expression inhibitor
CN103442678A (en) * 2010-10-04 2013-12-11 卡普龙股份有限公司 Cosmetic skin care compositions
CA2841411C (en) * 2011-07-13 2017-09-12 University Of Georgia Research Foundation, Inc. Use of xanthophyll carotenoids to improve visual performance and neural efficiency
CN103798808A (en) * 2012-11-15 2014-05-21 中国科学院大连化学物理研究所 Nutrient formula and application thereof to food or medicine for reliving asthenopia
WO2016025394A2 (en) * 2014-08-11 2016-02-18 Board Of Supervisors Of Louisiana State University And Agriculatural And Mechanical College Delivery of bioactive, nanoencapsulated antioxidants
RU2748400C2 (en) * 2014-11-25 2021-05-25 Ликоред Лтд. Biologically active tomato composition with reduced licopine content
JP6148780B1 (en) * 2016-02-05 2017-06-14 参天製薬株式会社 A composition containing xanthophyll and a processed plant of the genus Hishi
JP7105532B2 (en) * 2017-05-10 2022-07-25 ロート製薬株式会社 Composition for prevention, improvement or treatment of posterior segment disease
US20200113846A1 (en) * 2017-07-25 2020-04-16 Tathagata DUTTA A topical ocular suspension of antioxidants
WO2019087189A1 (en) * 2017-11-01 2019-05-09 Lycored Ltd. A method for improving ocular blood flow
US11696593B2 (en) 2018-08-24 2023-07-11 Bioscience Formulators, LLC Astaxanthin nutritional compositions and uses

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6103756A (en) * 1999-08-11 2000-08-15 Vitacost Inc. Ocular orally ingested composition for prevention and treatment of individuals
US6573299B1 (en) * 1999-09-20 2003-06-03 Advanced Medical Instruments Method and compositions for treatment of the aging eye

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6103756A (en) * 1999-08-11 2000-08-15 Vitacost Inc. Ocular orally ingested composition for prevention and treatment of individuals
US6573299B1 (en) * 1999-09-20 2003-06-03 Advanced Medical Instruments Method and compositions for treatment of the aging eye

Also Published As

Publication number Publication date
EP1937240A2 (en) 2008-07-02
WO2007046083A2 (en) 2007-04-26
JP2009515821A (en) 2009-04-16
MX2008004981A (en) 2008-10-17
RU2008119234A (en) 2009-11-27
AU2006305546A1 (en) 2007-04-26
IL190779A0 (en) 2009-02-11

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Free format text: PEDIDO RETIRADO, UMA VEZ QUE, SEGUNDO O ART. 216 INCISO 2O DA LPI, O DOCUMENTO DE PROCURACAO NAO FOI PROTOCOLADO EM SESSENTA DIAS CONTADOS DA PRATICA DO PRIMEIRO ATO DA PARTE NO PROCESSO, E NAO HOUVE MANIFESTACAO DO REQUERENTE FRENTE A PUBLICACAO DO ARQUIVAMENTO DA PETICAO (11.6.1) NA RPI 2150 DE 20/03/2012.