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WO2006064449A1 - Detoxifying and immunity-booster composition - Google Patents

Detoxifying and immunity-booster composition Download PDF

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Publication number
WO2006064449A1
WO2006064449A1 PCT/IB2005/054183 IB2005054183W WO2006064449A1 WO 2006064449 A1 WO2006064449 A1 WO 2006064449A1 IB 2005054183 W IB2005054183 W IB 2005054183W WO 2006064449 A1 WO2006064449 A1 WO 2006064449A1
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WO
WIPO (PCT)
Prior art keywords
treatment composition
approximately
composition
immunity
base
Prior art date
Application number
PCT/IB2005/054183
Other languages
French (fr)
Inventor
Cornelis Floris Van Der Westhuizen
Original Assignee
Van Der Westhuizen Cornelis Fl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Van Der Westhuizen Cornelis Fl filed Critical Van Der Westhuizen Cornelis Fl
Publication of WO2006064449A1 publication Critical patent/WO2006064449A1/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/01Hydrocarbons
    • A61K31/015Hydrocarbons carbocyclic
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135Bacteria or derivatives thereof, e.g. probiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/742Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747Lactobacilli, e.g. L. acidophilus or L. brevis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/062Ascomycota
    • A61K36/064Saccharomycetales, e.g. baker's yeast
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/07Bacillus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Definitions

  • This invention relates to a treatment composition for use in treating human subjects to enhance their general immunity.
  • the invention also extends to a method of producing the treatment composition.
  • a detoxifying and immunity-booster treatment composition suitable for use in enhancing immunity in human subjects, the treatment composition comprising a base composition of microbes, and fulvic acid.
  • the treatment composition may comprise approximately 50% by volume of the base composition added to approximately 50% by volume of fulvic acid.
  • the base composition also may include humic acids, amino acids, molasses, water and/or fish emulsion or extract.
  • the base composition may have a pH of between 2.8 and 3.6, and preferably a pH of 3.2.
  • the microbes of the base composition may be Bacillus Laterosporus, although the applicant anticipates that other microbes could also be used, including Lactobacillus and Saccharomyces boulardii.
  • the fulvic acid may have a concentration of approximately 9%.
  • the composition also may include one or more selected vitamins.
  • the vitamins may constitute approximately 1% of the composition.
  • a method of producing a detoxifying and immunity-booster treatment composition suitable for use in enhancing immunity in human subjects including the steps of multiplying a base culture of a microbe, for example Bacillus Laterosporus, Lactobacillus or Saccharomyces boulardii, in a suitable growth medium; preparing an approximately 9% concentration of fulvic acid; preparing a base composition including amino acids, fulvic acids, humic acids, molasses, water and/or fish emulsion or extract; introducing the base culture into the base composition and allowing the base culture further to multiply until it reaches a concentration of approximately 10 million and above organisms per millilitre; and introducing approximately 50% by volume of the base composition to approximately 50% by volume of the fulvic acid.
  • the method may include the steps of maintaining the treatment composition at approximately 23 0 C and in the absence of UV light. It may include the further step of stirring the treatment composition at least once a day.
  • the invention extends to a treatment composition comprising a base composition of microbes, and fulvic acid for use in enhancing immunity in human subjects.
  • the invention also includes the use of a base composition of microbes, and fulvic acid in the preparation of a detoxifying and immunity-booster treatment composition for use in enhancing immunity in human subjects.
  • the base composition had a pH of between 3.8 and 4.
  • the base composition was left, for a few days until the Bacillus Laterosporus had multiplied to a concentration of approximately 10 million organisms per millilitre.
  • the applicant then prepared fulvic acid at a concentration of approximately 9% and added approximately 50% by volume of the base composition to approximately 50% by volume of the fulvic acid.
  • the treatment composition so obtained had a pH of approximately 3.2.
  • the treatment composition was subsequently used in experimental trials during which it was given to a number of human patients suffering from one or more of the following conditions, namely HIV and Aids, tuberculosis, immunity deficiencies, and poor digestion.
  • the treatment composition according to the invention was given to five patients who were already in an advanced stage of infection. Some of these patients suffered from chronic illness and were no longer able to function properly. After receiving the treatment composition for a period of 6 weeks, conditions of these patients had improved sufficiently enough to enable them to function normally. Some of the chronically ill patients had improved so dramatically that they were able to return to work on a fulltime basis.
  • TB tuberculosis
  • the treatment composition was also given to five body builders on a daily basis. It was found that the treatment composition had a similar effect on muscle building than anabolic steroids, without the presence of unwanted side effects normally experienced with the latter. It was suggested that the treatment composition could be used as an alternative to plant protein supplements that are often consumed by body builders.
  • Digestive track dysfunction The treatment composition was also given to patients who were suffering from stomach ailments, and particularly from diarrhoea. These patients recovered within 30 minutes of taking the treatment composition.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention relates to a detoxifying and immunity-booster treatment composition suitable for use in enhancing immunity in human subjects, the treatment composition comprising a base composition of microbes, and fulvic acid. In particular, the treatment composition may comprise approximately 50% by volume of the base composition added to approximately 50% by volume of fulvic acid. The base composition also may include humic acids, molasses, water and/or fish emulsion or extract. The fulvic acid may have a concentration of approximately 9%.

Description

DETOXIFYING AND IMMUNITY-BOOSTER COMPOSITION
TECHNICAL FIELD
This invention relates to a treatment composition for use in treating human subjects to enhance their general immunity. The invention also extends to a method of producing the treatment composition.
DISCLOSURE OF THE INVENTION
According to a first aspect of the invention there is provided a detoxifying and immunity-booster treatment composition suitable for use in enhancing immunity in human subjects, the treatment composition comprising a base composition of microbes, and fulvic acid.
The treatment composition may comprise approximately 50% by volume of the base composition added to approximately 50% by volume of fulvic acid.
The base composition also may include humic acids, amino acids, molasses, water and/or fish emulsion or extract.
The base composition may have a pH of between 2.8 and 3.6, and preferably a pH of 3.2.
The microbes of the base composition may be Bacillus Laterosporus, although the applicant anticipates that other microbes could also be used, including Lactobacillus and Saccharomyces boulardii.
The fulvic acid may have a concentration of approximately 9%.
The composition also may include one or more selected vitamins. The vitamins may constitute approximately 1% of the composition. According to another aspect of the invention there is provided a method of producing a detoxifying and immunity-booster treatment composition suitable for use in enhancing immunity in human subjects, the method including the steps of multiplying a base culture of a microbe, for example Bacillus Laterosporus, Lactobacillus or Saccharomyces boulardii, in a suitable growth medium; preparing an approximately 9% concentration of fulvic acid; preparing a base composition including amino acids, fulvic acids, humic acids, molasses, water and/or fish emulsion or extract; introducing the base culture into the base composition and allowing the base culture further to multiply until it reaches a concentration of approximately 10 million and above organisms per millilitre; and introducing approximately 50% by volume of the base composition to approximately 50% by volume of the fulvic acid.
The method may include the steps of maintaining the treatment composition at approximately 230C and in the absence of UV light. It may include the further step of stirring the treatment composition at least once a day.
The invention extends to a treatment composition comprising a base composition of microbes, and fulvic acid for use in enhancing immunity in human subjects.
The invention also includes the use of a base composition of microbes, and fulvic acid in the preparation of a detoxifying and immunity-booster treatment composition for use in enhancing immunity in human subjects.
SPECIFIC EMBODIMENT OF THE INVENTION
Without limiting the scope thereof, the invention will now further be described by way of examples only.
The applicant prepared 1000 litres of a base composition as follows:
Figure imgf000004_0001
The base composition had a pH of between 3.8 and 4.
The base composition was left, for a few days until the Bacillus Laterosporus had multiplied to a concentration of approximately 10 million organisms per millilitre. The applicant then prepared fulvic acid at a concentration of approximately 9% and added approximately 50% by volume of the base composition to approximately 50% by volume of the fulvic acid. The treatment composition so obtained had a pH of approximately 3.2.
The treatment composition was subsequently used in experimental trials during which it was given to a number of human patients suffering from one or more of the following conditions, namely HIV and Aids, tuberculosis, immunity deficiencies, and poor digestion.
In cases of severe lack of immunity, patients received 10 ml of the treatment composition with 250 ml of water after breakfast. In less severe cases, patients received a dosage of 5 ml of the treatment composition with 250 ml water after breakfast. It was found that if the treatment composition were taken late in the afternoon, some patients encountered difficulties in falling asleep. The applicant believes that this results from an increased metabolism caused by the treatment composition. After 2 weeks' treatment with the treatment composition, patients were subjected to detoxifying exercises to effect drainage of the limbic system. In some cases, this resulted in short-term body aches resulting from the detoxifying process. HIV and Aids patients
The treatment composition according to the invention was given to five patients who were already in an advanced stage of infection. Some of these patients suffered from chronic illness and were no longer able to function properly. After receiving the treatment composition for a period of 6 weeks, conditions of these patients had improved sufficiently enough to enable them to function normally. Some of the chronically ill patients had improved so dramatically that they were able to return to work on a fulltime basis.
Patients suffering from tuberculosis ("TB") The treatment composition was given to three patients that had been suffering from TB in excess of 2 years. After treatment with the treatment composition for a period of 2 months, the patients had recovered completely from TB.
Patients suffering from immunity deficiencies Twenty patients that were all suffering from chronic immunity deficiencies were treated with the treatment composition according to the invention by daily dosing with the composition. Initially, during the detoxifying phase, the majority of patients complained of various body aches. However, after only one month, the patients' conditions had improved remarkably and the feedback was very positive. Previously chronic infections had been cured and it was no longer necessary to take pro-biotic supplements to stabilise the immune system.
After two months' treatment most female patients' hormonal functions and muscle tone had improved, and menstrual cycles had normalised.
Body builders
The treatment composition was also given to five body builders on a daily basis. It was found that the treatment composition had a similar effect on muscle building than anabolic steroids, without the presence of unwanted side effects normally experienced with the latter. It was suggested that the treatment composition could be used as an alternative to plant protein supplements that are often consumed by body builders.
Digestive track dysfunction The treatment composition was also given to patients who were suffering from stomach ailments, and particularly from diarrhoea. These patients recovered within 30 minutes of taking the treatment composition.
It will be appreciated that many variations in detail are possible without departing from the spirit or scope of the invention as defined in the claims.

Claims

1. A detoxifying and immunity-booster treatment composition suitable for use in enhancing immunity in human subjects, the treatment composition comprising a base composition of microbes, and fulvic acid.
2. The treatment composition according to claim 1 comprising approximately 50% by volume of the base composition added to approximately 50% by volume of fulvic acid.
3. The treatment composition according to claim 1 characterised therein that the base composition also includes humic acids, amino acids, molasses, water and/or fish emulsion or extract
4. The treatment composition according to claim 1 characterised therein that the base composition has a pH of between 2.8 and 3.6, and preferably a pH of 3.2.
5. The treatment composition according to claim 1 characterised therein that the microbes of the base composition may be selected from a group including Bacillus Laterosporus, Lactobacillus or Saccharomyces boulardii.
6. The treatment composition according to claim 1 characterised therein that the fulvic acid has a concentration of approximately 9%.
7. The treatment composition according to claim 1 characterised therein that it also includes one or more selected vitamins, more particularly the vitamins may constitute approximately 1% of the composition.
8. A method of producing a detoxifying and immunity-booster treatment composition suitable for use in enhancing immunity in human subjects, the method including the steps of multiplying a base culture of a microbe, for example Bacillus Laterosporus, Lactobacillus or Saccharomyces boulardii, in a suitable growth medium; preparing an approximately 9% concentration of fulvic acid; preparing a base composition including amino acids, fulvic acids, humic acids, molasses, water and/or fish emulsion or extract; introducing the base culture into the base composition and allowing the base culture further to multiply until it reaches a concentration of approximately 10 million and above organisms per millilitre; and introducing approximately 50% by volume of the base composition to approximately 50% by volume of the fulvic acid.
9. The method according to claim 8 characterised therein that it includes the steps of maintaining the treatment composition at approximately 230C and in the absence of UV light.
10. The method according to claim 8 characterised therein that it includes the further step of stirring the treatment composition at least once a day.
11. A treatment composition comprising a base composition of microbes, and fulvic acid for use in enhancing immunity in human subjects.
12. The use of a base composition of microbes, and fulvic acid in the preparation of a detoxifying and immunity-booster treatment composition for use in enhancing immunity in human subjects.
13. A detoxifying and immunity-booster treatment composition according to claims 1 and 11 substantially as herein described and exemplified with reference to the accompanying examples.
14. A method of producing a detoxifying and immunity-booster treatment composition according to claim 8 substantially as herein described and exemplified with reference to the accompanying examples.
15. The use of a base composition of microbes, and fulvic acid according to claim 12 substantially as herein described and exemplified with reference to the accompanying examples.
PCT/IB2005/054183 2004-12-15 2005-12-12 Detoxifying and immunity-booster composition WO2006064449A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ZA2004/10130 2004-12-15
ZA200410130 2004-12-15

Publications (1)

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WO2006064449A1 true WO2006064449A1 (en) 2006-06-22

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2753609C1 (en) * 2020-10-16 2021-08-18 Николай Иванович Милов Antiviral humic agent
WO2022041352A1 (en) * 2020-08-26 2022-03-03 河北科星药业有限公司 Feed additive for preventing diarrhea and improving immunity, and preparation method therefor and application thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2674755A1 (en) * 1991-04-05 1992-10-09 Thorel Jean Noel Novel immunostimulatory medicinal compositions
WO2000019999A1 (en) * 1998-10-08 2000-04-13 Enerkom (Proprietary) Limited Fulvic acid and its use in the treatment of various conditions
US20040029127A1 (en) * 2000-05-25 2004-02-12 Eric Postaire Use of lactobacillus case in immunostimulatory peptides
WO2004034808A1 (en) * 2002-10-18 2004-04-29 Biogaia Ab Method of improving immune function in mammals using lactobacillus reuteri strains
WO2005036969A1 (en) * 2003-10-15 2005-04-28 Van Der Westhuizen Cornelis Fl Composition for treating crops and plants against nematodes

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2674755A1 (en) * 1991-04-05 1992-10-09 Thorel Jean Noel Novel immunostimulatory medicinal compositions
WO2000019999A1 (en) * 1998-10-08 2000-04-13 Enerkom (Proprietary) Limited Fulvic acid and its use in the treatment of various conditions
US20040029127A1 (en) * 2000-05-25 2004-02-12 Eric Postaire Use of lactobacillus case in immunostimulatory peptides
WO2004034808A1 (en) * 2002-10-18 2004-04-29 Biogaia Ab Method of improving immune function in mammals using lactobacillus reuteri strains
WO2005036969A1 (en) * 2003-10-15 2005-04-28 Van Der Westhuizen Cornelis Fl Composition for treating crops and plants against nematodes

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MEYDANI S N ET AL: "IMMUNOLOGIC EFFECTS OF YOGURT", AMERICAN JOURNAL OF CLINICAL NUTRITION, BETHESDA,MD, US, vol. 71, no. 4, 2000, pages 861 - 872, XP000952410, ISSN: 0002-9165 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022041352A1 (en) * 2020-08-26 2022-03-03 河北科星药业有限公司 Feed additive for preventing diarrhea and improving immunity, and preparation method therefor and application thereof
RU2753609C1 (en) * 2020-10-16 2021-08-18 Николай Иванович Милов Antiviral humic agent

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Publication number Publication date
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