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WO2006053116A3 - Rizatriptan process - Google Patents

Rizatriptan process Download PDF

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Publication number
WO2006053116A3
WO2006053116A3 PCT/US2005/040718 US2005040718W WO2006053116A3 WO 2006053116 A3 WO2006053116 A3 WO 2006053116A3 US 2005040718 W US2005040718 W US 2005040718W WO 2006053116 A3 WO2006053116 A3 WO 2006053116A3
Authority
WO
WIPO (PCT)
Prior art keywords
rizatriptan
hydrazinophenylmethyl
reacting
prepared
hydrochloric acid
Prior art date
Application number
PCT/US2005/040718
Other languages
French (fr)
Other versions
WO2006053116A2 (en
Inventor
Padi Pratap Reddy
Sonny Sebastian
Saurabh Shashikant Chitre
Peri Seetha Rama Sarma
Bhimavarapu Srinivasa Reddy
Sankineni Sampath Kumar
Original Assignee
Reddys Lab Ltd Dr
Reddys Lab Inc Dr
Padi Pratap Reddy
Sonny Sebastian
Saurabh Shashikant Chitre
Peri Seetha Rama Sarma
Bhimavarapu Srinivasa Reddy
Sankineni Sampath Kumar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reddys Lab Ltd Dr, Reddys Lab Inc Dr, Padi Pratap Reddy, Sonny Sebastian, Saurabh Shashikant Chitre, Peri Seetha Rama Sarma, Bhimavarapu Srinivasa Reddy, Sankineni Sampath Kumar filed Critical Reddys Lab Ltd Dr
Publication of WO2006053116A2 publication Critical patent/WO2006053116A2/en
Publication of WO2006053116A3 publication Critical patent/WO2006053116A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Rizatriptan is prepared by reacting 4-hydrazinophenylmethyl-1,2,4-triazole dihydrochloride with 4-N,N-dimethylaminobutanal dimethylacetal in the presence of hydrochloric acid.
PCT/US2005/040718 2004-11-10 2005-11-09 Rizatriptan process WO2006053116A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62772004P 2004-11-10 2004-11-10
US60/627,720 2004-11-10

Publications (2)

Publication Number Publication Date
WO2006053116A2 WO2006053116A2 (en) 2006-05-18
WO2006053116A3 true WO2006053116A3 (en) 2006-12-07

Family

ID=36337209

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/040718 WO2006053116A2 (en) 2004-11-10 2005-11-09 Rizatriptan process

Country Status (1)

Country Link
WO (1) WO2006053116A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2121663A2 (en) * 2006-12-15 2009-11-25 Aurobindo Pharma Limited An improved process for the preparation of rizatriptan
EP2160390A1 (en) * 2007-06-04 2010-03-10 Generics Ýuk¨Limited Novel process
CN103664900B (en) * 2013-11-25 2016-02-24 四川大学 A kind of method preparing rizatriptan benzoate

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5567827A (en) * 1992-06-23 1996-10-22 Elf Sanofi 4-Hydroxyphenylthio derivatives, their preparation and their use for the preparation of aminoalkoxyphenylsulphonyl derivatives
US5602162A (en) * 1991-02-01 1997-02-11 Merck, Sharp & Dohme Ltd. Imidazole, triazole and tetrazole derivatives

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5602162A (en) * 1991-02-01 1997-02-11 Merck, Sharp & Dohme Ltd. Imidazole, triazole and tetrazole derivatives
US5567827A (en) * 1992-06-23 1996-10-22 Elf Sanofi 4-Hydroxyphenylthio derivatives, their preparation and their use for the preparation of aminoalkoxyphenylsulphonyl derivatives

Also Published As

Publication number Publication date
WO2006053116A2 (en) 2006-05-18

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