WO2005115368A1 - Carrier composition for topical formulations - Google Patents
Carrier composition for topical formulations Download PDFInfo
- Publication number
- WO2005115368A1 WO2005115368A1 PCT/EG2004/000023 EG2004000023W WO2005115368A1 WO 2005115368 A1 WO2005115368 A1 WO 2005115368A1 EG 2004000023 W EG2004000023 W EG 2004000023W WO 2005115368 A1 WO2005115368 A1 WO 2005115368A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- topical
- topical formulations
- carrier composition
- urea
- propylene glycol
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
Definitions
- Carrier composition for topical formulations are provided.
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A new pharmaceutical product to minimize the side effects encountered with the use of local products via using a special carrier vehicle, composed of urea, propylene glycol and lactic acid.
Description
Carrier composition for topical formulations
Technical Field
A new pharmaceutical product to minimize the side effects encountered with the use of local products via using a special carrier vehicle, composed of urea, propylene glycol and lactic acid.
Background Art Minimizing the side effects encountered with the use of local products via using a special carrier vehicle, composed of urea, propylene glycol and lactic acid. This vehicle, gives many benefits, such as: 1. Enhancing the penetrability of these active ingredients. 2. Adding antibacterial, antifungal or anti-inflammatory effect to the formula. 3. The possibility of lowering the dose and/or duration of treatment. 4. Adding a cosmetic effect to the skin. Topical active ingredients used are in the following categories: 1. Anti-inflammatory. 2. Antifungal. 3. Antibacterial.
Disclosure of the Invention
Adding these active ingredients to the special vehicle was through three stages: I. Chemical- Pharmaceutical phase; determining the compatibility and possibility of using the vehicle for these active ingredients. II. Pharmacological- Toxicological phase; determining in vivo and in vitro studies to show primary effects. III. Clinical phase; undergoing double-blind, placebo- controlled, multi- centered study in three Egyptian Universities, to assure the clinical results.
Urea, propylene glycol and lactic acid base was used with the following active ingredients: Corticosteroids, topical:
Claims
1. The compositions of the admitted formulae.
2. The indications included. Urea, propylene glycol and lactic acid base was used with the following active ingredients: Corticosteroids, topical:
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EG2004/000023 WO2005115368A1 (en) | 2004-05-31 | 2004-05-31 | Carrier composition for topical formulations |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EG2004/000023 WO2005115368A1 (en) | 2004-05-31 | 2004-05-31 | Carrier composition for topical formulations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO2005115368A1 true WO2005115368A1 (en) | 2005-12-08 |
Family
ID=35450640
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/EG2004/000023 WO2005115368A1 (en) | 2004-05-31 | 2004-05-31 | Carrier composition for topical formulations |
Country Status (1)
| Country | Link |
|---|---|
| WO (1) | WO2005115368A1 (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1987004617A1 (en) * | 1986-02-04 | 1987-08-13 | Sven Moberg | Pharmaceutical compositions containing propylene glycol and/or polyethylene glycol and urea as active main components and use thereof |
| WO2004000291A1 (en) * | 2002-06-21 | 2003-12-31 | Dermatrends, Inc. | Topical administration of basic antifungal compositions to treat fungal infections of the nails |
-
2004
- 2004-05-31 WO PCT/EG2004/000023 patent/WO2005115368A1/en not_active Application Discontinuation
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1987004617A1 (en) * | 1986-02-04 | 1987-08-13 | Sven Moberg | Pharmaceutical compositions containing propylene glycol and/or polyethylene glycol and urea as active main components and use thereof |
| WO2004000291A1 (en) * | 2002-06-21 | 2003-12-31 | Dermatrends, Inc. | Topical administration of basic antifungal compositions to treat fungal infections of the nails |
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