[go: up one dir, main page]

WO2005034863A3 - Countermeasures against malaria - Google Patents

Countermeasures against malaria Download PDF

Info

Publication number
WO2005034863A3
WO2005034863A3 PCT/US2004/032761 US2004032761W WO2005034863A3 WO 2005034863 A3 WO2005034863 A3 WO 2005034863A3 US 2004032761 W US2004032761 W US 2004032761W WO 2005034863 A3 WO2005034863 A3 WO 2005034863A3
Authority
WO
WIPO (PCT)
Prior art keywords
compounds
malaria
class
countermeasures against
against malaria
Prior art date
Application number
PCT/US2004/032761
Other languages
French (fr)
Other versions
WO2005034863A2 (en
Inventor
Victor Amoah
Anthony Pandolfo
Ted Batkin
Charlie Richards
Original Assignee
Jarikuma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jarikuma Corp filed Critical Jarikuma Corp
Publication of WO2005034863A2 publication Critical patent/WO2005034863A2/en
Publication of WO2005034863A3 publication Critical patent/WO2005034863A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/2442—Chitinase (3.2.1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01014—Chitinase (3.2.1.14)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Insects & Arthropods (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The present invention includes compounds useful for the control of malaria. One class of compounds includes cysteine proteases that are active against mosquitoes and a second class of compounds includes chimeric proteins having a defensin portion and either a chitinase inhibitor portion or a chitin binding protein portion, wherein the two portions are joined by a linker. Also included in the invention are methods of controlling malaria by application of compounds of the invention to mosquito habitats.
PCT/US2004/032761 2003-10-03 2004-10-04 Countermeasures against malaria WO2005034863A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50862703P 2003-10-03 2003-10-03
US60/508,627 2003-10-03

Publications (2)

Publication Number Publication Date
WO2005034863A2 WO2005034863A2 (en) 2005-04-21
WO2005034863A3 true WO2005034863A3 (en) 2006-04-27

Family

ID=34434924

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/032761 WO2005034863A2 (en) 2003-10-03 2004-10-04 Countermeasures against malaria

Country Status (1)

Country Link
WO (1) WO2005034863A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6388408B2 (en) 2012-06-08 2018-09-12 アルカーメス ファーマ アイルランド リミテッド Ligands modified by circulating substitution as agonists and antagonists
EP3573639A4 (en) * 2017-01-24 2020-12-23 Flagship Pioneering Innovations V, Inc. Compositions and related methods for controlling vector-borne diseases
EP3573465A4 (en) 2017-01-24 2020-11-04 Flagship Pioneering Innovations V, Inc. PROCESSES AND RELATED COMPOSITIONS FOR THE MANUFACTURING OF FOOD AND FEED
UA126575C2 (en) * 2017-01-24 2022-11-02 Флегшіп Пайонірінг Інновейшнз V, Інк. COMPOSITION AND METHOD OF CONTROL OF DISEASES TRANSMITTED BY VECTORS
US20190387748A1 (en) * 2017-01-24 2019-12-26 Flagship Pioneering Innovations V, Inc. Compositions and related methods for agriculture
US11350648B2 (en) 2017-01-24 2022-06-07 Flagship Pioneering Innovations V, Inc. Compositions and related methods for agriculture
CN111132552A (en) 2017-02-24 2020-05-08 旗舰创业创新五公司 Compositions and related methods for modulating endosymbionts
US11471433B1 (en) 2019-08-01 2022-10-18 Flagship Pioneering Innovations V, Inc. Postbiotic compositions and related methods for agriculture
AU2020394444A1 (en) 2019-11-25 2022-05-19 Alkermes, Inc. Substituted macrocyclic compounds and related methods of treatment

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003153687A (en) * 2001-11-20 2003-05-27 Japan Tissue Engineering:Kk Cultured cell tissue piece and method for producing the same

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003153687A (en) * 2001-11-20 2003-05-27 Japan Tissue Engineering:Kk Cultured cell tissue piece and method for producing the same

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DATABASE GENESEQ [online] "Novel cultured fragment obtained by culturing a cell comprises cells whose surface has biologically active peptide and that contains bioactive region, secretion region and immobilizing part", XP002996141, accession no. NCBI Database accession no. (ADC49345) *
DATABASE GENPEPT [online] 16 July 1999 (1999-07-16), MATSUYAMA K. ET AL.: "Molecular cloning of cDNA for sapecin and unique expression of the sapecin gene", XP002996140, accession no. NCBI Database accession no. (A31792) *
DATABASE UNIPROT [online] RICHMAN A.M. ET AL.: "Inducible immune factors of the vector mosquito Anopheles gambiae: biochemical purification of a defensin antibacterial peptide and molecular cloning of preprodefensin cDNA", XP002996142, accession no. EMBL Database accession no. (Q17027) *
INSECT. MOL., vol. 5, 1996, pages 203 - 210 *
J. BIOLOGICAL CHEMISTRY, vol. 263, no. 32, 1998, pages 17117 - 17121 *

Also Published As

Publication number Publication date
WO2005034863A2 (en) 2005-04-21

Similar Documents

Publication Publication Date Title
WO2003011115A3 (en) Peptide-based multimeric targeted contrast agents
WO2008030266A3 (en) Insecticidal n-substituted (heteroaryl)alkyl sulfilmines
WO2007075525A3 (en) Combination of an iap-inhibitor and a taxane7
BR0209511B1 (en) synergistic herbicidal composition, and method for controlling undesirable vegetation.
WO2005049593A3 (en) N-acylsulfonamide apoptosis promoters
WO2005049078A3 (en) Immunoglobulin preparations having increased stability
WO2007133290A3 (en) Anti-ox40l antibodies and methods using same
MX2009002303A (en) Insecticidal n-substituted (heteroaryl)cycloalkyl sulfoximines.
WO2006108552A3 (en) Pesticidal mixtures
WO2006127757A3 (en) Interferon-igg fusion
DE60332711D1 (en) NEW INSECTICIDES PROTEINS FROM BAZILLUS THURINGIENSIS
WO2005034863A3 (en) Countermeasures against malaria
IL178505A0 (en) Active ingredient combinations having insecticidal properties
WO2004031229A3 (en) P53 binding polypeptide
WO2005070959A3 (en) Compositions comprising immune response altering agents and methods of use
WO2008153429A3 (en) A protease from staphylococcus aureus, particularly spia or spib, peptides it recognises and their use
WO2006083927A3 (en) Antimicrobial agent
WO2005059131A3 (en) Protein binding miniature proteins and uses thereof
WO2006019982A3 (en) Pin1-modulating compounds and methods of use thereof
WO2006032697A3 (en) MODIFIED VPl-CAPSID PROTEIN OF PARVOVIRUS B19
WO2007057393A3 (en) Aqueous rodenticide formulations
WO2007042287A3 (en) Onion flavour compounds and use
NO20071606L (en) Use of IL-16 in vascular complications
WO2006046134A3 (en) Method of screening by using conformation sensitive peptides
WO2003057712A3 (en) Humanized lactoferrin and uses thereof

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
122 Ep: pct application non-entry in european phase