WO2004104596A3 - Diagnostics and therapeutics for diseases associated with igs70 (igs70) - Google Patents
Diagnostics and therapeutics for diseases associated with igs70 (igs70) Download PDFInfo
- Publication number
- WO2004104596A3 WO2004104596A3 PCT/EP2004/004965 EP2004004965W WO2004104596A3 WO 2004104596 A3 WO2004104596 A3 WO 2004104596A3 EP 2004004965 W EP2004004965 W EP 2004004965W WO 2004104596 A3 WO2004104596 A3 WO 2004104596A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- disorders
- igs70
- diseases
- compounds
- gastrointestinal
- Prior art date
Links
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 6
- 201000010099 disease Diseases 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 208000035475 disorder Diseases 0.000 abstract 3
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 2
- 208000018522 Gastrointestinal disease Diseases 0.000 abstract 2
- 208000012902 Nervous system disease Diseases 0.000 abstract 2
- 208000025966 Neurological disease Diseases 0.000 abstract 2
- 210000000750 endocrine system Anatomy 0.000 abstract 2
- 230000002496 gastric effect Effects 0.000 abstract 2
- 208000027866 inflammatory disease Diseases 0.000 abstract 2
- 208000019423 liver disease Diseases 0.000 abstract 2
- 208000030159 metabolic disease Diseases 0.000 abstract 2
- 208000023504 respiratory system disease Diseases 0.000 abstract 2
- 208000014001 urinary system disease Diseases 0.000 abstract 2
- 238000003556 assay Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 208000014951 hematologic disease Diseases 0.000 abstract 1
- 229940088597 hormone Drugs 0.000 abstract 1
- 239000005556 hormone Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
- C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Endocrinology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
The invention provides a human IGS70 which is associated with the cardiovascular disorders, dermatological disorders, endocrine system and hon-none disorders, inflammatory diseases, gastrointestinal and liver diseases, hernatological disorders, respiratory diseases, neurological disorders, metabolic diseases and urological disorders. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular disorders, dermatological disorders, endocrine system and hormone disorders, inflammatory diseases, gastrointestinal and liver diseases, hematological disorders, respiratory diseases, neurological disorders, metabolic diseases and urological disorders. The invention also features compounds which bind to and/or activate or inhibit the activity of IGS70 as well as pharmaceutical compositions comprising such compounds.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03011592 | 2003-05-22 | ||
| EP03011592.7 | 2003-05-22 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2004104596A2 WO2004104596A2 (en) | 2004-12-02 |
| WO2004104596A3 true WO2004104596A3 (en) | 2005-06-09 |
Family
ID=33462085
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/EP2004/004965 WO2004104596A2 (en) | 2003-05-22 | 2004-05-10 | Diagnostics and therapeutics for diseases associated with igs70 (igs70) |
Country Status (1)
| Country | Link |
|---|---|
| WO (1) | WO2004104596A2 (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001096567A1 (en) * | 2000-06-15 | 2001-12-20 | Takeda Chemical Industries, Ltd. | Novel g protein-coupled receptor protein and dna thereof |
| WO2002042461A2 (en) * | 2000-11-27 | 2002-05-30 | Arena Pharmaceuticals, Inc. | Endogenous and non-endogenous versions of human g protein-coupled receptors |
| WO2002044212A2 (en) * | 2000-11-30 | 2002-06-06 | Deleersnijder, Willy | Human g-protein coupled receptor and uses thereof |
| EP1225183A2 (en) * | 2001-01-23 | 2002-07-24 | Pfizer Limited | Human G-protein coupled receptor |
| WO2002063004A2 (en) * | 2001-02-07 | 2002-08-15 | Incyte Genomics, Inc. | G-protein coupled receptors |
-
2004
- 2004-05-10 WO PCT/EP2004/004965 patent/WO2004104596A2/en active Application Filing
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001096567A1 (en) * | 2000-06-15 | 2001-12-20 | Takeda Chemical Industries, Ltd. | Novel g protein-coupled receptor protein and dna thereof |
| WO2002042461A2 (en) * | 2000-11-27 | 2002-05-30 | Arena Pharmaceuticals, Inc. | Endogenous and non-endogenous versions of human g protein-coupled receptors |
| WO2002044212A2 (en) * | 2000-11-30 | 2002-06-06 | Deleersnijder, Willy | Human g-protein coupled receptor and uses thereof |
| EP1225183A2 (en) * | 2001-01-23 | 2002-07-24 | Pfizer Limited | Human G-protein coupled receptor |
| WO2002063004A2 (en) * | 2001-02-07 | 2002-08-15 | Incyte Genomics, Inc. | G-protein coupled receptors |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004104596A2 (en) | 2004-12-02 |
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