WO2004005489A3 - Nucleic acids encoding sarcocystic neurona antigen and uses thereof - Google Patents
Nucleic acids encoding sarcocystic neurona antigen and uses thereof Download PDFInfo
- Publication number
- WO2004005489A3 WO2004005489A3 PCT/US2003/004856 US0304856W WO2004005489A3 WO 2004005489 A3 WO2004005489 A3 WO 2004005489A3 US 0304856 W US0304856 W US 0304856W WO 2004005489 A3 WO2004005489 A3 WO 2004005489A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- provides
- nucleic acids
- nucleic acid
- sarcocystis neurona
- encoded
- Prior art date
Links
- 150000007523 nucleic acids Chemical class 0.000 title abstract 10
- 102000039446 nucleic acids Human genes 0.000 title abstract 7
- 108020004707 nucleic acids Proteins 0.000 title abstract 7
- 239000000427 antigen Substances 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
- 241000146987 Sarcocystis neurona Species 0.000 abstract 6
- 239000012634 fragment Substances 0.000 abstract 5
- 229920001184 polypeptide Polymers 0.000 abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 5
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 5
- 230000000890 antigenic effect Effects 0.000 abstract 4
- 239000013598 vector Substances 0.000 abstract 2
- 238000001514 detection method Methods 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
Abstract
The present invention provides novel isolated nucleic acids encoding antigenic proteins derived from Sarcocystis neurona, or unique fragments thereof In particular, the invention provides novel isolated nucleic acids encoding membrane-associated polypeptides SnSAG2, SnSAG3, and SnSAG 4. Also provided are purified antigenic polypeptide fragments encoded by the novel nucleic acid sequences set forth herein that encode for Sarcocystis neurona. In particular, the invention provides purified antigenic polypeptide fragments encoded by the novel nucleic acid sequences set forth herein that encode for SnSAG2, SnSAG3, and SnSAG 4. Further, the invention provides a purified antigenic polypeptide fragment encoded by the nucleic acid sequences set forth herein or a selective portion thereof, in a pharmaceutically acceptable carrier. Also provided isolated nucleic acids capable of selectively hybridizing with the nucleic acid from Sarcocystis neurona. The invention also provides vectors comprising the nucleic acids of the invention encoding Sarcocystis neurona or a unique fragment thereof and provides the vector in a host capable of expressing the polypeptide encoded by that nucleic acid. Finally, the invention provides a purified polyclonal and/or a monoclonal antibody specifically reactive with Sarcocystis neurona and a method of detection of Sarcocystis neurona utilizing the antibodies of the invention.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2003217568A AU2003217568A1 (en) | 2002-02-15 | 2003-02-19 | Nucleic acids encoding sarcocystic neurona antigen and uses thereof |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35747902P | 2002-02-15 | 2002-02-15 | |
| US60/357,479 | 2002-02-15 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2004005489A2 WO2004005489A2 (en) | 2004-01-15 |
| WO2004005489A3 true WO2004005489A3 (en) | 2005-03-03 |
Family
ID=30115457
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/US2003/004856 WO2004005489A2 (en) | 2002-02-15 | 2003-02-19 | Nucleic acids encoding sarcocystic neurona antigen and uses thereof |
Country Status (2)
| Country | Link |
|---|---|
| AU (1) | AU2003217568A1 (en) |
| WO (1) | WO2004005489A2 (en) |
-
2003
- 2003-02-19 AU AU2003217568A patent/AU2003217568A1/en not_active Abandoned
- 2003-02-19 WO PCT/US2003/004856 patent/WO2004005489A2/en not_active Application Discontinuation
Non-Patent Citations (1)
| Title |
|---|
| DATABASE GENBANK [online] "Sarcocystis neurona EST project", XP002904286, Database accession no. (BM252380) * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004005489A2 (en) | 2004-01-15 |
| AU2003217568A8 (en) | 2004-01-23 |
| AU2003217568A1 (en) | 2004-01-23 |
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