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WO2004003188A3 - Stabilization of granules - Google Patents

Stabilization of granules Download PDF

Info

Publication number
WO2004003188A3
WO2004003188A3 PCT/DK2003/000456 DK0300456W WO2004003188A3 WO 2004003188 A3 WO2004003188 A3 WO 2004003188A3 DK 0300456 W DK0300456 W DK 0300456W WO 2004003188 A3 WO2004003188 A3 WO 2004003188A3
Authority
WO
WIPO (PCT)
Prior art keywords
matrix
granules
weight
polymer
active compound
Prior art date
Application number
PCT/DK2003/000456
Other languages
French (fr)
Other versions
WO2004003188A2 (en
Inventor
Ole Simonsen
Erik Kjaer Markussen
Hanne Roejel
Svend Kaasgaard
Thomas Hoenger Callisen
Christian Isak Joergensen
Original Assignee
Novozymes As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes As filed Critical Novozymes As
Priority to EP03761448A priority Critical patent/EP1517981A2/en
Priority to JP2004516525A priority patent/JP2005531308A/en
Priority to AU2003243926A priority patent/AU2003243926A1/en
Publication of WO2004003188A2 publication Critical patent/WO2004003188A2/en
Publication of WO2004003188A3 publication Critical patent/WO2004003188A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D17/00—Detergent materials or soaps characterised by their shape or physical properties
    • C11D17/0039—Coated compositions or coated components in the compositions, (micro)capsules
    • A—HUMAN NECESSITIES
    • A21—BAKING; EDIBLE DOUGHS
    • A21D—TREATMENT OF FLOUR OR DOUGH FOR BAKING, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS
    • A21D8/00—Methods for preparing or baking dough
    • A21D8/02—Methods for preparing dough; Treating dough prior to baking
    • A21D8/04—Methods for preparing dough; Treating dough prior to baking treating dough with microorganisms or enzymes
    • A21D8/042—Methods for preparing dough; Treating dough prior to baking treating dough with microorganisms or enzymes with enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/189—Enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K40/00—Shaping or working-up of animal feeding-stuffs
    • A23K40/10—Shaping or working-up of animal feeding-stuffs by agglomeration; by granulation, e.g. making powders
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K40/00—Shaping or working-up of animal feeding-stuffs
    • A23K40/30—Shaping or working-up of animal feeding-stuffs by encapsulating; by coating
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/30—Encapsulation of particles, e.g. foodstuff additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0216—Solid or semisolid forms
    • A61K8/022—Powders; Compacted Powders
    • A61K8/0225—Granulated powders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/11—Encapsulated compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/0005—Other compounding ingredients characterised by their effect
    • C11D3/0042—Reducing agents
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/0005—Other compounding ingredients characterised by their effect
    • C11D3/0084—Antioxidants; Free-radical scavengers
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/37—Polymers
    • C11D3/3746—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C11D3/3753—Polyvinylalcohol; Ethers or esters thereof
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/37—Polymers
    • C11D3/3746—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C11D3/3769—(Co)polymerised monomers containing nitrogen, e.g. carbonamides, nitriles or amines
    • C11D3/3776—Heterocyclic compounds, e.g. lactam
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38672—Granulated or coated enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/60—Particulates further characterized by their structure or composition
    • A61K2800/61—Surface treated
    • A61K2800/62—Coated
    • A61K2800/63—More than one coating

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Animal Husbandry (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Detergent Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Fodder In General (AREA)
  • Bakery Products And Manufacturing Methods Therefor (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Cosmetics (AREA)
  • Glanulating (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to granules comprising a core matrix and one or more coatings, wherein the core matrix comprises: An active compound, a synthetic polymer, where the amount of polymer added is 0.1 to 10 % by weight of the matrix, and one or more antioxidants and/or reducing agents, where the amount of antioxidant and/or reducing agent is 0.2 to 5 % by weight of the matrix. The active compound is an enzyme, e.g. savinase. The synthetic polymer is a polyvinyl polymer selected from the group consisting of PVP, PVA and copolymers thereof. A preferred antioxidant is sodium thiosulfate.
PCT/DK2003/000456 2002-07-01 2003-07-01 Stabilization of granules WO2004003188A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP03761448A EP1517981A2 (en) 2002-07-01 2003-07-01 Stabilization of granules
JP2004516525A JP2005531308A (en) 2002-07-01 2003-07-01 Granule stabilization
AU2003243926A AU2003243926A1 (en) 2002-07-01 2003-07-01 Stabilization of granules

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200201023 2002-07-01
DKPA200201023 2002-07-01

Publications (2)

Publication Number Publication Date
WO2004003188A2 WO2004003188A2 (en) 2004-01-08
WO2004003188A3 true WO2004003188A3 (en) 2004-02-26

Family

ID=29797024

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DK2003/000456 WO2004003188A2 (en) 2002-07-01 2003-07-01 Stabilization of granules

Country Status (5)

Country Link
EP (1) EP1517981A2 (en)
JP (1) JP2005531308A (en)
CN (1) CN1656205A (en)
AU (1) AU2003243926A1 (en)
WO (1) WO2004003188A2 (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7425528B2 (en) * 2002-07-01 2008-09-16 Novozymes A/S Stabilization of granules
KR101183565B1 (en) 2003-06-20 2012-09-17 뉴트리니아 리미티드 Bioactive compounds protection method and compositions containing the same
PL1804592T3 (en) * 2004-09-27 2010-04-30 Novozymes As Enzyme granules
CA2587138A1 (en) * 2004-11-29 2006-06-01 Basf Aktiengesellschaft Enzyme formulations
DE12159269T1 (en) * 2005-10-12 2014-02-13 Danisco Us Inc. Stable, durable granules with active ingredients
EP1994130A1 (en) * 2006-03-02 2008-11-26 Novozymes A/S High capacity encapsulation process
DE102006053071A1 (en) * 2006-11-10 2008-05-15 Ab Enzymes Gmbh Protein-containing substance with increased temperature stability
US7892536B2 (en) * 2006-12-20 2011-02-22 Daniso US Inc. Storage-stable glucose oxidase
WO2008084093A2 (en) * 2007-01-11 2008-07-17 Novozymes A/S Particles comprising active compounds
DK2350250T4 (en) † 2008-11-03 2023-03-06 Danisco Us Inc Administrationssystem for coformuleret enzym og substrat
MX349735B (en) 2010-04-26 2017-08-10 Novozymes As Enzyme granules.
DE102011007627A1 (en) * 2011-04-18 2012-10-18 Henkel Ag & Co. Kgaa Detergents or cleaning agents with solid enzyme preparation
EP2537918A1 (en) 2011-06-20 2012-12-26 The Procter & Gamble Company Consumer products with lipase comprising coated particles
EP2721137B1 (en) 2011-06-20 2017-11-01 Novozymes A/S Particulate composition
CN102533708B (en) * 2011-12-29 2013-06-05 青岛蔚蓝生物集团有限公司 Enzyme particle coated with alkali protease and preparation method thereof
EP3004313A1 (en) * 2013-05-30 2016-04-13 Novozymes A/S Particulate enzyme composition
CN105640819A (en) * 2014-11-13 2016-06-08 广州十长生化妆品有限公司 Skin tendering smoothening whitening exfoliating microsphere and application thereof
SG11201808154XA (en) 2016-03-24 2018-10-30 Nutrinia Ltd Use of insulin for promoting gastric emptying
JP7387095B2 (en) 2018-03-16 2023-11-28 味の素株式会社 Feed additives and feed
CN108949372B (en) * 2018-07-31 2021-07-13 安徽澳瑞药业有限责任公司 Fabric washing liquid containing polymer coated enzyme preparation and preparation method thereof
CN108795588B (en) * 2018-07-31 2021-01-26 福建植嘉生物科技有限公司 Enzyme-containing laundry gel ball and preparation method thereof
CN108998276B (en) * 2018-08-03 2021-05-14 东莞市激浪洗涤科技有限公司 Washing powder containing reduction whitening agent and preparation method thereof
GB202005073D0 (en) 2020-04-06 2020-05-20 Mellizyme Biotechnology Ltd Enzymatic degradation of plastics
GB202114239D0 (en) 2021-10-05 2021-11-17 Mellizyme Biotechnology Ltd Oxidative transformation of small molecules

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0206418A2 (en) * 1985-06-28 1986-12-30 The Procter & Gamble Company Dry bleach and stable enzyme granular composition
EP0320219A1 (en) * 1987-12-09 1989-06-14 The Procter & Gamble Company Detergent compositions
US5254287A (en) * 1985-08-21 1993-10-19 The Clorox Company Encapsulated enzyme in dry bleach composition
US5739091A (en) * 1992-08-14 1998-04-14 Kiesser; Torsten W. Enzyme granulates
US5972669A (en) * 1995-07-28 1999-10-26 Gist-Brocades, B.V. Salt-stabilized enzyme preparations
WO2000001793A1 (en) * 1998-06-30 2000-01-13 Novozymes A/S A new improved enzyme containing granule
US6268329B1 (en) * 1998-06-30 2001-07-31 Nouozymes A/S Enzyme containing granule

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2436602T3 (en) * 1999-07-09 2014-01-03 Novozymes A/S Process for the preparation of a granule containing enzymes

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0206418A2 (en) * 1985-06-28 1986-12-30 The Procter & Gamble Company Dry bleach and stable enzyme granular composition
US5254287A (en) * 1985-08-21 1993-10-19 The Clorox Company Encapsulated enzyme in dry bleach composition
EP0320219A1 (en) * 1987-12-09 1989-06-14 The Procter & Gamble Company Detergent compositions
US5739091A (en) * 1992-08-14 1998-04-14 Kiesser; Torsten W. Enzyme granulates
US5972669A (en) * 1995-07-28 1999-10-26 Gist-Brocades, B.V. Salt-stabilized enzyme preparations
WO2000001793A1 (en) * 1998-06-30 2000-01-13 Novozymes A/S A new improved enzyme containing granule
US6268329B1 (en) * 1998-06-30 2001-07-31 Nouozymes A/S Enzyme containing granule
US20010044403A1 (en) * 1998-06-30 2001-11-22 Novozymes A/S Enzyme containing granule

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
A. L. GAERTNER ET AL: "Development of low dust enzyme detergent granules with high storage stability", PROCEED. INT'L. SYMP. CONTROL. REL. BLOACT. MATER., CONTROLLED RELEASE SOCIETY, INC., vol. 25, 1998, pages 289 - 290, XP002262053 *

Also Published As

Publication number Publication date
WO2004003188A2 (en) 2004-01-08
EP1517981A2 (en) 2005-03-30
AU2003243926A1 (en) 2004-01-19
CN1656205A (en) 2005-08-17
AU2003243926A8 (en) 2004-01-19
JP2005531308A (en) 2005-10-20

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