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WO2003023391A3 - Procede et agents permettant la mesure directe de composes de la vitamine d dans le serum ou le plasma - Google Patents

Procede et agents permettant la mesure directe de composes de la vitamine d dans le serum ou le plasma Download PDF

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Publication number
WO2003023391A3
WO2003023391A3 PCT/EP2002/009740 EP0209740W WO03023391A3 WO 2003023391 A3 WO2003023391 A3 WO 2003023391A3 EP 0209740 W EP0209740 W EP 0209740W WO 03023391 A3 WO03023391 A3 WO 03023391A3
Authority
WO
WIPO (PCT)
Prior art keywords
vitamin
serum
plasma
compounds
agents
Prior art date
Application number
PCT/EP2002/009740
Other languages
German (de)
English (en)
Other versions
WO2003023391A2 (fr
Inventor
Franz Paul Armbruster
Sabine Friedl
Original Assignee
Immundiagnostik Ag
Franz Paul Armbruster
Sabine Friedl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immundiagnostik Ag, Franz Paul Armbruster, Sabine Friedl filed Critical Immundiagnostik Ag
Publication of WO2003023391A2 publication Critical patent/WO2003023391A2/fr
Publication of WO2003023391A3 publication Critical patent/WO2003023391A3/fr

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

L'invention concerne un procédé et un tampon échantillon pour une analyse en mesure directe permettant le dosage de composés de la vitamine D, tels que 25-hydroxy-vitamine-D2, 25-hydroxy-vitamine-D3. 1α,25-dihydroxy-vitamine-D2, 1α,25-dihydroxy-vitamine-D3 dans le plasma ou le sérum. Le dosage est basé sur une analyse des liaisons protéine à des anticorps à la place de la protéine de liaison à la vitamine D contre le composé de vitamine D à déterminer. L'invention est caractérisée en ce que le tampon d'échantillon et d'analyse renferme, pour un pH légèrement acide préféré, au moins 0,05 % en poids d'un acide carboxylique aromatique hydroxylé soluble ou d'un sel de celui-ci, de préférence 1 à 7 % en poids de salicylate de sodium ou de potassium pour un pH compris entre 3,0 et 7,0 et, éventuellement, de la cyclodextrine.
PCT/EP2002/009740 2001-09-12 2002-08-30 Procede et agents permettant la mesure directe de composes de la vitamine d dans le serum ou le plasma WO2003023391A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2001144905 DE10144905C2 (de) 2001-09-12 2001-09-12 Bestimmung von Vitamin-D direkt in Serum oder Plasma
DE10144905.4 2001-09-12

Publications (2)

Publication Number Publication Date
WO2003023391A2 WO2003023391A2 (fr) 2003-03-20
WO2003023391A3 true WO2003023391A3 (fr) 2003-12-18

Family

ID=7698763

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/009740 WO2003023391A2 (fr) 2001-09-12 2002-08-30 Procede et agents permettant la mesure directe de composes de la vitamine d dans le serum ou le plasma

Country Status (2)

Country Link
DE (1) DE10144905C2 (fr)
WO (1) WO2003023391A2 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2374942T3 (es) 2005-09-29 2012-02-23 F. Hoffmann-La Roche Ag Reactivo de liberación para compuestos de vitamina d.
PT2126586E (pt) 2007-02-01 2010-09-17 Immundiagnostik Ag Determinação directa de vitamina d no soro ou plasma
US20110097733A1 (en) 2009-10-27 2011-04-28 Michel Anciaux Process for the production of a hybridoma and antibody obtained therefrom, able to recognize more than one vitamin d metabolite
EP2372365A1 (fr) * 2010-04-01 2011-10-05 Future Diagnostics B.V. Analyse directe pour la vitamine D
JP5711811B2 (ja) 2010-05-20 2015-05-07 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ ビタミンｄ化合物の解離試薬
EP2635611B1 (fr) * 2010-12-28 2017-01-11 Future Diagnostics B.V. Réactif de libération pour la vitamine d
WO2012136720A1 (fr) 2011-04-04 2012-10-11 Immundiagnostik Ag Détermination de métabolites de vitamine d dans du sang séché
CN103946710B (zh) 2011-11-18 2015-08-26 霍夫曼-拉罗奇有限公司 维生素d化合物的释放制剂
US10073103B1 (en) 2013-03-11 2018-09-11 Theranos Ip Company, Llc Rapid measurement of total vitamin D in blood
US20140273021A1 (en) * 2013-03-14 2014-09-18 Enzo Biochem, Inc. Vitamin d assays
WO2017039574A1 (fr) * 2015-08-28 2017-03-09 Enzo Life Sciences, Inc. Dosages de vitamine d
JP7300452B2 (ja) 2018-01-03 2023-06-29 イムーンダイアグノスティック・アー・ゲー エンドサイトーシスビタミンｄの状態の測定方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0753743A2 (fr) * 1995-07-14 1997-01-15 NHH Biologics Analyse de la vitamine D
US5981779A (en) * 1995-12-29 1999-11-09 A And D Assay, Incorporated Labeled vitamin D compounds and the use thereof
WO2002046746A2 (fr) * 2000-12-06 2002-06-13 Immunodiagnostic Systems Ltd Procede de detection de metabolites de la vitamine d

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06109727A (ja) * 1992-08-14 1994-04-22 Wisconsin Alumni Res Found １，２５−ジヒドロキシビタミンｄの検定法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0753743A2 (fr) * 1995-07-14 1997-01-15 NHH Biologics Analyse de la vitamine D
US5981779A (en) * 1995-12-29 1999-11-09 A And D Assay, Incorporated Labeled vitamin D compounds and the use thereof
WO2002046746A2 (fr) * 2000-12-06 2002-06-13 Immunodiagnostic Systems Ltd Procede de detection de metabolites de la vitamine d

Also Published As

Publication number Publication date
WO2003023391A2 (fr) 2003-03-20
DE10144905C2 (de) 2003-07-31
DE10144905A1 (de) 2003-04-10

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