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WO2003009885A3 - Hemofiltration systems, methods and devices used to treat inflammatory mediator related disease - Google Patents

Hemofiltration systems, methods and devices used to treat inflammatory mediator related disease Download PDF

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Publication number
WO2003009885A3
WO2003009885A3 PCT/US2002/023603 US0223603W WO03009885A3 WO 2003009885 A3 WO2003009885 A3 WO 2003009885A3 US 0223603 W US0223603 W US 0223603W WO 03009885 A3 WO03009885 A3 WO 03009885A3
Authority
WO
WIPO (PCT)
Prior art keywords
stream
ultrafiltrate
related disease
methods
inflammatory mediator
Prior art date
Application number
PCT/US2002/023603
Other languages
French (fr)
Other versions
WO2003009885A2 (en
Inventor
James R Matson
Patrice A Lee
Original Assignee
Immunocept L L C
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/912,904 external-priority patent/US6730266B2/en
Application filed by Immunocept L L C filed Critical Immunocept L L C
Priority to EP02750294A priority Critical patent/EP1409041A4/en
Priority to AU2002319690A priority patent/AU2002319690A1/en
Publication of WO2003009885A2 publication Critical patent/WO2003009885A2/en
Publication of WO2003009885A3 publication Critical patent/WO2003009885A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A61M1/3486—Biological, chemical treatment, e.g. chemical precipitation; treatment by absorbents

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • External Artificial Organs (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

A hemofiltration system for a mammal comprises a hemofilter and an adsorbent device. The hemofilter removes ultrafiltrate from a blood stream extracted from the mammal to create a filtered blood stream and an ultrafiltrate stream. The adsorbent device is comprised of one or more adsorbent materials and is used to adsorb inflammatory mediators from the ultrafiltrate stream received from the hemofilter removing inflammatory mediators that cause inflammatory mediator related disease, sepsis, and SIRS/MODS/MOSF to create a post adsorption ultrafiltrate stream. The post adsorption ultrafiltrate stream is selectively combined with the filtered blood stream and together with the filtered blood stream is returned to the mammal.
PCT/US2002/023603 2001-07-25 2002-07-24 Hemofiltration systems, methods and devices used to treat inflammatory mediator related disease WO2003009885A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP02750294A EP1409041A4 (en) 2001-07-25 2002-07-24 Hemofiltration systems, methods and devices used to treat inflammatory mediator related disease
AU2002319690A AU2002319690A1 (en) 2001-07-25 2002-07-24 Hemofiltration systems, methods and devices used to treat inflammatory mediator related disease

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/912,904 US6730266B2 (en) 1998-07-10 2001-07-25 Hemofiltration systems, methods and devices used to treat inflammatory mediator related disease
US09/912,904 2001-07-25

Publications (2)

Publication Number Publication Date
WO2003009885A2 WO2003009885A2 (en) 2003-02-06
WO2003009885A3 true WO2003009885A3 (en) 2003-07-03

Family

ID=25432668

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/023603 WO2003009885A2 (en) 2001-07-25 2002-07-24 Hemofiltration systems, methods and devices used to treat inflammatory mediator related disease

Country Status (3)

Country Link
EP (1) EP1409041A4 (en)
AU (1) AU2002319690A1 (en)
WO (1) WO2003009885A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8038638B2 (en) 2004-02-23 2011-10-18 Hemolife Medical, Inc. Plasma detoxification and volume control system and methods of use
US8339447B2 (en) 2004-10-21 2012-12-25 Truevision Systems, Inc. Stereoscopic electronic microscope workstation
ES2348189T3 (en) * 2007-01-12 2010-12-01 Bellco S.R.L. KIT FOR THE TREATMENT OF DISEASES RELATED TO SYSTEMATIC INFLAMMATION.
JP5670336B2 (en) 2008-10-02 2015-02-18 ユニヴァーシティ オヴ ピッツバーグ オヴ ザ コモンウェルス システム オヴ ハイアー エデュケーション Administration of polymer adsorbents for the treatment of systemic inflammation
CN106659834B (en) 2014-08-26 2019-06-18 3M创新有限公司 System for removing pro-inflammatory mediator and granulocyte and monocyte in blood

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0098392A2 (en) * 1982-07-02 1984-01-18 Gambro Dialysatoren GmbH & Co. KG Filtration membrane and process for producing the membrane
US4844810A (en) * 1986-08-08 1989-07-04 Hospal Industrie Installation with multiple functions for replacement of the natural filtration of the blood
US5536412A (en) * 1992-02-06 1996-07-16 Hemocleanse, Inc. Hemofiltration and plasmafiltration devices and methods
US5571418A (en) * 1993-08-20 1996-11-05 Lee; Patrice A. Hemofiltration of toxic mediator-related disease
EP0787500A1 (en) * 1996-02-06 1997-08-06 BELLCO S.p.A. Method and device for extracorporeal removal of toxins, in particular cytokines
US5858238A (en) * 1996-03-08 1999-01-12 Baxter Research Medical, Inc. Salvage of autologous blood via selective membrane/sorption technologies

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6287516B1 (en) * 1998-07-10 2001-09-11 Immunocept, L.L.C. Hemofiltration systems, methods, and devices used to treat inflammatory mediator related disease

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0098392A2 (en) * 1982-07-02 1984-01-18 Gambro Dialysatoren GmbH & Co. KG Filtration membrane and process for producing the membrane
US4844810A (en) * 1986-08-08 1989-07-04 Hospal Industrie Installation with multiple functions for replacement of the natural filtration of the blood
US5536412A (en) * 1992-02-06 1996-07-16 Hemocleanse, Inc. Hemofiltration and plasmafiltration devices and methods
US5571418A (en) * 1993-08-20 1996-11-05 Lee; Patrice A. Hemofiltration of toxic mediator-related disease
EP0787500A1 (en) * 1996-02-06 1997-08-06 BELLCO S.p.A. Method and device for extracorporeal removal of toxins, in particular cytokines
US5858238A (en) * 1996-03-08 1999-01-12 Baxter Research Medical, Inc. Salvage of autologous blood via selective membrane/sorption technologies

Also Published As

Publication number Publication date
AU2002319690A1 (en) 2003-02-17
EP1409041A2 (en) 2004-04-21
EP1409041A4 (en) 2007-05-16
WO2003009885A2 (en) 2003-02-06

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