WO2002010383A1 - Genes codant des proteines capables de regenerer la luciferine, adn recombine et methode de production de proteines capables de regenerer la luciferine - Google Patents
Genes codant des proteines capables de regenerer la luciferine, adn recombine et methode de production de proteines capables de regenerer la luciferine Download PDFInfo
- Publication number
- WO2002010383A1 WO2002010383A1 PCT/JP2001/006454 JP0106454W WO0210383A1 WO 2002010383 A1 WO2002010383 A1 WO 2002010383A1 JP 0106454 W JP0106454 W JP 0106454W WO 0210383 A1 WO0210383 A1 WO 0210383A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- regenerating luciferin
- protein
- recombinant dna
- luciferin
- regenerating
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 12
- 102000004169 proteins and genes Human genes 0.000 title abstract 7
- IGXWBGJHJZYPQS-SSDOTTSWSA-N D-Luciferin Chemical compound OC(=O)[C@H]1CSC(C=2SC3=CC=C(O)C=C3N=2)=N1 IGXWBGJHJZYPQS-SSDOTTSWSA-N 0.000 title abstract 6
- CYCGRDQQIOGCKX-UHFFFAOYSA-N Dehydro-luciferin Natural products OC(=O)C1=CSC(C=2SC3=CC(O)=CC=C3N=2)=N1 CYCGRDQQIOGCKX-UHFFFAOYSA-N 0.000 title abstract 6
- BJGNCJDXODQBOB-UHFFFAOYSA-N Fivefly Luciferin Natural products OC(=O)C1CSC(C=2SC3=CC(O)=CC=C3N=2)=N1 BJGNCJDXODQBOB-UHFFFAOYSA-N 0.000 title abstract 6
- DDWFXDSYGUXRAY-UHFFFAOYSA-N Luciferin Natural products CCc1c(C)c(CC2NC(=O)C(=C2C=C)C)[nH]c1Cc3[nH]c4C(=C5/NC(CC(=O)O)C(C)C5CC(=O)O)CC(=O)c4c3C DDWFXDSYGUXRAY-UHFFFAOYSA-N 0.000 title abstract 6
- 230000001172 regenerating effect Effects 0.000 title abstract 6
- 108020004511 Recombinant DNA Proteins 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 3
- 108020004414 DNA Proteins 0.000 abstract 2
- 238000007792 addition Methods 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 230000000295 complement effect Effects 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 238000012217 deletion Methods 0.000 abstract 1
- 230000037430 deletion Effects 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Insects & Arthropods (AREA)
- Tropical Medicine & Parasitology (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
La présente invention concerne un gène isolé ou synthétisé codant une protéine contenant la séquence d'acides aminés représentée par SEQ ID NO: 2 ; un gène isolé ou synthétisé codant une protéine contenant une séquence d'acides aminés obtenue via la séquence d'acides aminés représentée par SEQ ID NO: 2 par délétion, substitution ou addition d'un ou de plusieurs acides aminés, et capable de régénérer la luciférine; un gène isolé ou synthétisé codant une protéine pouvant être hybridée avec la séquence complémentaire d'un ADN contenant la séquence de base représentée par SEQ ID NO: 1 dans des conditions rigoureuses, et capable de régénérer la luciférine; un ADN recombiné caractérisé en ce qu'il contient un gène synthétisé ou isolé précité introduit dans un ADN vecteur; un transformant ou un transductant contenant l'ADN recombiné précité; et enfin, une méthode de production d'une protéine capable de régénérer la luciférine, consistant à mettre en culture le transformant ou le transductant précité dans un milieu donné et à recueillir la protéine capable de régénérer la luciférine dans ladite culture.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE60123077T DE60123077T2 (de) | 2000-07-28 | 2001-07-26 | Gene welche für proteine, die befähigt sind luziferin zu regenerieren, kodieren, rekombinante dna und verfahren zur herstellung von proteinen, die befähigt sind luziferin zu regenerieren |
| EP01954352A EP1306434B1 (fr) | 2000-07-28 | 2001-07-26 | Genes codant des proteines capables de regenerer la luciferine, adn recombine et methode de production de proteines capables de regenerer la luciferine |
| US10/343,002 US7049113B2 (en) | 2000-07-28 | 2001-07-26 | Gene encoding protein capable of regenerating luciferin, recombinant DNA and process for producing protein capable of regenerating luciferin |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000-228226 | 2000-07-28 | ||
| JP2000228226A JP3891323B2 (ja) | 2000-07-28 | 2000-07-28 | ルシフェリンを再生する能力を有するタンパク質をコードする遺伝子、組み換え体ｄｎａ及びルシフェリンを再生する能力を有するタンパク質の製造法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO2002010383A1 true WO2002010383A1 (fr) | 2002-02-07 |
Family
ID=18721557
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/JP2001/006454 WO2002010383A1 (fr) | 2000-07-28 | 2001-07-26 | Genes codant des proteines capables de regenerer la luciferine, adn recombine et methode de production de proteines capables de regenerer la luciferine |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7049113B2 (fr) |
| EP (1) | EP1306434B1 (fr) |
| JP (1) | JP3891323B2 (fr) |
| AT (1) | ATE339499T1 (fr) |
| DE (1) | DE60123077T2 (fr) |
| WO (1) | WO2002010383A1 (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070178450A1 (en) * | 2006-01-27 | 2007-08-02 | Microphage (Tm) Incorporation | Method and apparatus for determining level of microorganisms using bacteriophage |
| WO2010147066A1 (fr) * | 2009-06-15 | 2010-12-23 | オリンパスメディカルシステムズ株式会社 | Dispositif d'introduction d'un objet à l'intérieur de l'organisme d'un sujet et système d'acquisition d'informations in vivo |
| CN101955528B (zh) * | 2010-08-05 | 2012-07-04 | 许爱娥 | 人mchr1抗原表位区基因表达相关蛋白mchr1-c及其编码基因 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5814504A (en) * | 1996-08-22 | 1998-09-29 | Kikkoman Corporation | Protein involved in regenerating firefly luciferin |
| WO2001025426A1 (fr) * | 1999-10-06 | 2001-04-12 | Kikkoman Corporation | Gene codant une proteine pouvant regenerer la luciferine, nouvel adn recombinant, et procede de production d'une proteine pouvant regenerer la luciferine |
-
2000
- 2000-07-28 JP JP2000228226A patent/JP3891323B2/ja not_active Expired - Fee Related
-
2001
- 2001-07-26 WO PCT/JP2001/006454 patent/WO2002010383A1/fr active IP Right Grant
- 2001-07-26 DE DE60123077T patent/DE60123077T2/de not_active Expired - Fee Related
- 2001-07-26 EP EP01954352A patent/EP1306434B1/fr not_active Expired - Lifetime
- 2001-07-26 AT AT01954352T patent/ATE339499T1/de not_active IP Right Cessation
- 2001-07-26 US US10/343,002 patent/US7049113B2/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5814504A (en) * | 1996-08-22 | 1998-09-29 | Kikkoman Corporation | Protein involved in regenerating firefly luciferin |
| WO2001025426A1 (fr) * | 1999-10-06 | 2001-04-12 | Kikkoman Corporation | Gene codant une proteine pouvant regenerer la luciferine, nouvel adn recombinant, et procede de production d'une proteine pouvant regenerer la luciferine |
Also Published As
| Publication number | Publication date |
|---|---|
| DE60123077D1 (de) | 2006-10-26 |
| JP3891323B2 (ja) | 2007-03-14 |
| JP2002034573A (ja) | 2002-02-05 |
| EP1306434A4 (fr) | 2004-06-30 |
| EP1306434B1 (fr) | 2006-09-13 |
| ATE339499T1 (de) | 2006-10-15 |
| EP1306434A1 (fr) | 2003-05-02 |
| US20040185441A1 (en) | 2004-09-23 |
| DE60123077T2 (de) | 2007-03-29 |
| US7049113B2 (en) | 2006-05-23 |
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