[go: up one dir, main page]

WO2001048205A3 - Murine neu sequences and methods of use therefor - Google Patents

Murine neu sequences and methods of use therefor Download PDF

Info

Publication number
WO2001048205A3
WO2001048205A3 PCT/US2000/035648 US0035648W WO0148205A3 WO 2001048205 A3 WO2001048205 A3 WO 2001048205A3 US 0035648 W US0035648 W US 0035648W WO 0148205 A3 WO0148205 A3 WO 0148205A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
sequences
murine
use therefor
neu
Prior art date
Application number
PCT/US2000/035648
Other languages
French (fr)
Other versions
WO2001048205A2 (en
Inventor
A Gregory Spies
Original Assignee
Corixa Corp
A Gregory Spies
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corixa Corp, A Gregory Spies filed Critical Corixa Corp
Priority to AU27442/01A priority Critical patent/AU2744201A/en
Publication of WO2001048205A2 publication Critical patent/WO2001048205A2/en
Publication of WO2001048205A3 publication Critical patent/WO2001048205A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention is directed toward murine homologues of human Her-2/neu, as well as pharmaceutical compositions and vaccines comprising such sequences. Murine neu sequences are useful for immunotherapy of Her-2/neu associated cancers.
PCT/US2000/035648 1999-12-29 2000-12-29 Murine neu sequences and methods of use therefor WO2001048205A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU27442/01A AU2744201A (en) 1999-12-29 2000-12-29 Murine neu sequences and methods of use therefor

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47438299A 1999-12-29 1999-12-29
US09/474,382 1999-12-29

Publications (2)

Publication Number Publication Date
WO2001048205A2 WO2001048205A2 (en) 2001-07-05
WO2001048205A3 true WO2001048205A3 (en) 2002-02-07

Family

ID=23883274

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/035648 WO2001048205A2 (en) 1999-12-29 2000-12-29 Murine neu sequences and methods of use therefor

Country Status (2)

Country Link
AU (1) AU2744201A (en)
WO (1) WO2001048205A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1747970A (en) * 2003-02-06 2006-03-15 三肽公司 Antigen/antibody or ligand/receptor glycosylated specificity exchangers

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996030514A1 (en) * 1995-03-31 1996-10-03 University Of Washington Intracellular domain of the her-2/neu protein for prevention or treatment of malignancies
US5837243A (en) * 1995-06-07 1998-11-17 Medarex, Inc. Therapeutic compounds comprised of anti-Fc receptor antibodies
WO1999009956A1 (en) * 1997-08-29 1999-03-04 Corixa Corporation Rapid release encapsulated bioactive agents for inducing or potentiating an immune response and methods of using thereof
WO2000044899A1 (en) * 1999-01-29 2000-08-03 Corixa Corporation Her-2/neu fusion proteins
WO2001021192A2 (en) * 1999-09-22 2001-03-29 Corixa Corporation Methods for diagnosis and therapy of hematological and virus-associated malignancies
WO2001053463A2 (en) * 2000-01-21 2001-07-26 Corixa Corporation COMPOUNDS AND METHODS FOR PREVENTION AND TREATMENT OF HER-2/neu ASSOCIATED MALIGNANCIES

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996030514A1 (en) * 1995-03-31 1996-10-03 University Of Washington Intracellular domain of the her-2/neu protein for prevention or treatment of malignancies
US5837243A (en) * 1995-06-07 1998-11-17 Medarex, Inc. Therapeutic compounds comprised of anti-Fc receptor antibodies
WO1999009956A1 (en) * 1997-08-29 1999-03-04 Corixa Corporation Rapid release encapsulated bioactive agents for inducing or potentiating an immune response and methods of using thereof
WO2000044899A1 (en) * 1999-01-29 2000-08-03 Corixa Corporation Her-2/neu fusion proteins
WO2001021192A2 (en) * 1999-09-22 2001-03-29 Corixa Corporation Methods for diagnosis and therapy of hematological and virus-associated malignancies
WO2001053463A2 (en) * 2000-01-21 2001-07-26 Corixa Corporation COMPOUNDS AND METHODS FOR PREVENTION AND TREATMENT OF HER-2/neu ASSOCIATED MALIGNANCIES

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL 16 September 1995 (1995-09-16), MOSCOSO ET AL: "Mus musculus tyrosine kinase (erB2) mRNA, partial cds.", XP002178515 *
LIM H ET AL: "Differential expression if the erbB2 gene in the periimplantation mouse uterus: potential mediator of signaling by epidermal growht factor-like growth factors", ENDOCRINOLOGY., vol. 138, no. 3, March 1999 (1999-03-01), BALTIMORE, MD., US, pages 1328 - 1337, XP001028127, ISSN: 0013-7227 *
MOSCOSO LM ET AL: "Synapse-associated expression of an acetylcholine receptor-inducing protein, ARIA/Heregulin, and its putative receptors, ErbB2 and ErbB3, in developing mammalian muscle", DEVELOPMENTAL BIOLOGY, vol. 172, 1995, ACADEMIC PRESS, NEW YORK, NY, US, pages 158 - 169, XP001027857, ISSN: 0012-1606 *
SLAMON D J ET AL: "STUDIES OF THE HER-2/NEU PROTO-ONCOGENE IN HUMAN BREAST AND OVARIANCANCER", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 244, no. 4905, 12 May 1989 (1989-05-12), pages 707 - 712, XP002019974, ISSN: 0036-8075 *

Also Published As

Publication number Publication date
AU2744201A (en) 2001-07-09
WO2001048205A2 (en) 2001-07-05

Similar Documents

Publication Publication Date Title
AP1869A (en) b2- Adrenergic receptor agonists.
AU2002339865A1 (en) Methods and compositions useful for diagnosis, staging, and treatment of cancers and tumors
IN2012DN00313A (en)
AU5186799A (en) Peptides of il-2 and derivatives thereof and their use as therapeutic agents
YU38801A (en) Azabicycloalkanes as ccr5 modulators
MX9700885A (en) New heteroaryloxazolidinones.
AU3877500A (en) Methods for preparing 3-aryloxy-3-arylpropylamines and intermediates thereof
MY129263A (en) Vaccine composition
CY2261B1 (en) Cytotoxic amino sugar and relatd sugar derivativesof indolopyrrolocarbazoles
MXPA99001697A (en) Preparation of cyclohexene carboxylate derivatives.
NO963462L (en) Paramunity inducers based on combinations of poxvirus components, process for their preparation and use as a drug
ZA200203102B (en) Novel oligosaccharides, preparation method and pharmaceutical compositions containing same.
AU2001235006A1 (en) Prophylactic and therapeutic monoclonal antibodies
UA66865C2 (en) Indenopyrrolocarbazoles, pharmaceutical composition, method for inhibiting kinase activity and method for treatment (variants)
IL153680A0 (en) Aplidine derivatives and methods for the preparation thereof
WO2000066528A3 (en) Quinones for treatment of diseases
SE5292304T3 (en)
AUPP589598A0 (en) Novel peptides
AU6921300A (en) Novel glycoconjugates, glycoamino, acids, intermediates thereto, and uses thereof
MY127474A (en) Naphthyl compounds, intermediates, compositions, and methods of use
WO2002047613A3 (en) Immunogenic cancer peptides and uses thereof
YU10599A (en) Amorphous benzothiophenes, procedure for the preparatio thereof and their pharmaceutical formulation
WO2000055194A3 (en) Tuberculosis antigens and methods of use therefor
WO2001048205A3 (en) Murine neu sequences and methods of use therefor
HK1045987A1 (en) 3-amino-2-benzyl-1-phenyl-propane derivatives

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP