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WO2001042285A3 - Extracellular matrix and cell adhesion proteins as well as genes encoding them - Google Patents

Extracellular matrix and cell adhesion proteins as well as genes encoding them Download PDF

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Publication number
WO2001042285A3
WO2001042285A3 PCT/US2000/032990 US0032990W WO0142285A3 WO 2001042285 A3 WO2001042285 A3 WO 2001042285A3 US 0032990 W US0032990 W US 0032990W WO 0142285 A3 WO0142285 A3 WO 0142285A3
Authority
WO
WIPO (PCT)
Prior art keywords
extracellular matrix
cell adhesion
well
genes encoding
adhesion proteins
Prior art date
Application number
PCT/US2000/032990
Other languages
French (fr)
Other versions
WO2001042285A2 (en
Inventor
Henry Yue
Y Tom Tang
Preeti Lal
Neil Burford
Yalda Azimzai
Chandra Patterson
Mariah R Baughn
Dyung Aina M Lu
Purvi Shah
Janice Au-Young
Original Assignee
Incyte Genomics Inc
Henry Yue
Y Tom Tang
Preeti Lal
Neil Burford
Yalda Azimzai
Chandra Patterson
Mariah R Baughn
Dyung Aina M Lu
Purvi Shah
Au Young Janice
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc, Henry Yue, Y Tom Tang, Preeti Lal, Neil Burford, Yalda Azimzai, Chandra Patterson, Mariah R Baughn, Dyung Aina M Lu, Purvi Shah, Au Young Janice filed Critical Incyte Genomics Inc
Priority to EP00989218A priority Critical patent/EP1244695A2/en
Priority to JP2001543582A priority patent/JP2005503751A/en
Priority to CA002390093A priority patent/CA2390093A1/en
Priority to AU25756/01A priority patent/AU2575601A/en
Publication of WO2001042285A2 publication Critical patent/WO2001042285A2/en
Publication of WO2001042285A3 publication Critical patent/WO2001042285A3/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The invention provides human extracellular matrix and cell adhesion molecules (XMAD) and polynucleotides which identify and encode XMAD. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of XMAD.
PCT/US2000/032990 1999-12-10 2000-12-05 Extracellular matrix and cell adhesion proteins as well as genes encoding them WO2001042285A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP00989218A EP1244695A2 (en) 1999-12-10 2000-12-05 Extracellular matrix and cell adhesion proteins as well as genes encoding them
JP2001543582A JP2005503751A (en) 1999-12-10 2000-12-05 Extracellular matrix and cell adhesion molecules
CA002390093A CA2390093A1 (en) 1999-12-10 2000-12-05 Extracellular matrix and cell adhesion molecules
AU25756/01A AU2575601A (en) 1999-12-10 2000-12-05 Extracellular matrix and cell adhesion molecules

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US17285299P 1999-12-10 1999-12-10
US60/172,852 1999-12-10
US17235499P 1999-12-16 1999-12-16
US60/172,354 1999-12-16

Publications (2)

Publication Number Publication Date
WO2001042285A2 WO2001042285A2 (en) 2001-06-14
WO2001042285A3 true WO2001042285A3 (en) 2002-03-07

Family

ID=26867999

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/032990 WO2001042285A2 (en) 1999-12-10 2000-12-05 Extracellular matrix and cell adhesion proteins as well as genes encoding them

Country Status (5)

Country Link
EP (1) EP1244695A2 (en)
JP (1) JP2005503751A (en)
AU (1) AU2575601A (en)
CA (1) CA2390093A1 (en)
WO (1) WO2001042285A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6623923B1 (en) 1998-12-23 2003-09-23 Corixa Corporation Compounds for immunotherapy and diagnosis of colon cancer and methods for their use
EP1715043A3 (en) * 1998-12-23 2007-01-10 Corixa Corporation Compounds for immunotherapy and diagnosis of colon cancer and methods for their use
AU2375800A (en) 1998-12-23 2000-07-31 Immunex Corporation Lectin s3939 dna and polypeptides
AU2608201A (en) * 1999-12-30 2001-07-16 Corixa Corporation Compounds for immunotherapy and diagnosis of colon cancer and methods for their use
AUPR470101A0 (en) * 2001-05-02 2001-05-24 Murdoch Childrens Research Institute, The A molecular marker
AU2002360514A1 (en) * 2001-12-07 2003-06-23 The Government Of The United States Of America, As Represented By The Secretary, Department Of Healt hGC-1, A GENE ENCODING A MEMBER OF THE OLFACTOMEDIN-RELATED PROTEIN FAMILY
EP1622634A2 (en) * 2002-04-01 2006-02-08 Curagen Corporation Therapeutic polypeptides, nucleic acids encoding same, and methods of use
RU2730661C2 (en) * 2018-12-27 2020-08-24 Селл энд Джин Терапи Лтд Gene-therapeutic dna-vector based on gene-therapeutic dna-vector vtvaf17, carrying target gene selected from group of genes col1a1, col1a2, p4ha1, p4ha2, col7a1, clca2, eln, plod1 to increase level of expression of said target genes, method for production and use thereof, strain escherichia coli scs110-af/vtvaf17-col1a1, or escherichia coli scs110-af/vtvaf17-col1a2, or escherichia coli scs110-af/vtvaf17-p4ha1, or escherichia coli scs110-af/vtvaf17-p4ha2, or escherichia coli scs110-af/vtvaf17-col7a1, or escherichia coli scs110-af/vtvaf17-clca2, or escherichia coli scs110-af/vtvaf17-eln, or escherichia coli scs110-af/vtvaf17- plod1, carrying gene-therapeutic dna vector, method for production thereof, method for industrial production of gene-therapeutic dna vector

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999063088A2 (en) * 1998-06-02 1999-12-09 Genentech, Inc. Membrane-bound proteins and nucleic acids encoding the same
WO2000073469A2 (en) * 1999-05-28 2000-12-07 Sugen, Inc. Protein kinases

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999063088A2 (en) * 1998-06-02 1999-12-09 Genentech, Inc. Membrane-bound proteins and nucleic acids encoding the same
WO2000073469A2 (en) * 1999-05-28 2000-12-07 Sugen, Inc. Protein kinases

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL European Molecular Biology Organisation; 12 April 2000 (2000-04-12), LIU ETAL.: "Homo sapiens mixed lineage kinase mRNA, complete cds.", XP002165219 *
DATABASE EMBL European Molecular Biology Organisation; 13 October 2000 (2000-10-13), GOTHO ET AL.: "Identification and Characterization of a Novel MAP Kinase Kinase Kinase, MLTK", XP002167500 *
DATABASE EMBL European Molecular Biology Organisation; 2 November 1999 (1999-11-02), EDGAR AJ AND POLACK JM: "Homo sapiens vacuolar sorting protein VPS29/PEP11 mRNA, complete cds.", XP002165220 *
DATABASE EMBL European Molecular Biology Organisation; 25 August 2000 (2000-08-25), ABE AND UEDA: "Placible mixed lineage kinase derived from LAK cell", XP002167499 *
DATABASE EMBL European Molecular Biology Organisation; 27 April 2000 (2000-04-27), MCNEE ET AL.: "Cloning and Characterization of AZK, a mixed-lineage kinase containing a sterile-alpha motif", XP002167498 *
DATABASE EMBL European Molecular Biology Organisation; HILLIER ET AL.: "zl80d02.s1 Stratagene colon (#937204) Homo sapiens cDNA clone IMAGE:510915 3', mRNA sequence", XP002165218 *
LIU ET AL.: "Cloning and expression of ZAK, a mixed-lineage kinase-like protein containing a leucine-zipper and a sterile-alpha motif.", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 274, 11 August 2000 (2000-08-11), pages 811 - 816, XP002167497 *

Also Published As

Publication number Publication date
EP1244695A2 (en) 2002-10-02
CA2390093A1 (en) 2001-06-14
JP2005503751A (en) 2005-02-10
WO2001042285A2 (en) 2001-06-14
AU2575601A (en) 2001-06-18

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