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WO2001032665A3 - New ruthenium metal ligand complexes - Google Patents

New ruthenium metal ligand complexes Download PDF

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Publication number
WO2001032665A3
WO2001032665A3 PCT/US2000/041758 US0041758W WO0132665A3 WO 2001032665 A3 WO2001032665 A3 WO 2001032665A3 US 0041758 W US0041758 W US 0041758W WO 0132665 A3 WO0132665 A3 WO 0132665A3
Authority
WO
WIPO (PCT)
Prior art keywords
metal ligand
ligand complexes
ruthenium metal
new ruthenium
assays
Prior art date
Application number
PCT/US2000/041758
Other languages
French (fr)
Other versions
WO2001032665A2 (en
Inventor
Zakir Murtaza
Original Assignee
Fluorrx Inc
Zakir Murtaza
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fluorrx Inc, Zakir Murtaza filed Critical Fluorrx Inc
Priority to AU37913/01A priority Critical patent/AU3791301A/en
Publication of WO2001032665A2 publication Critical patent/WO2001032665A2/en
Publication of WO2001032665A3 publication Critical patent/WO2001032665A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0046—Ruthenium compounds
    • C07F15/0053—Ruthenium compounds without a metal-carbon linkage
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00—Labels used in chemical analysis of biological material
    • G01N2458/40—Rare earth chelates

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)

Abstract

A fluorescent metal ligand complex includes a transition metal associated with a complement of diamine ligands, which may be the same or different, one of which is amino reactive for attachment to biological molecules. The surprisingly long lifetime and high anisotropy ratio of the complexes make them especially useful in fluorescence polarization assays and in fluorescence resonance energy transfer assays.
PCT/US2000/041758 1999-11-01 2000-10-31 New ruthenium metal ligand complexes WO2001032665A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU37913/01A AU3791301A (en) 1999-11-01 2000-10-31 New ruthenium metal ligand complexes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16280799P 1999-11-01 1999-11-01
US60/162,807 1999-11-01

Publications (2)

Publication Number Publication Date
WO2001032665A2 WO2001032665A2 (en) 2001-05-10
WO2001032665A3 true WO2001032665A3 (en) 2001-10-11

Family

ID=22587208

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/041758 WO2001032665A2 (en) 1999-11-01 2000-10-31 New ruthenium metal ligand complexes

Country Status (2)

Country Link
AU (1) AU3791301A (en)
WO (1) WO2001032665A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103044495B (en) * 2013-01-21 2017-12-12 中国科学院福建物质结构研究所 Ruthenium luminescent material and its synthesis and application
CN103044494B (en) * 2013-01-21 2018-02-16 中国科学院福建物质结构研究所 Ruthenium organometallic polymer luminescent material and its synthesis and application
CN106893108B (en) * 2017-02-15 2019-04-16 中国科学院福建物质结构研究所 A kind of ruthenium rare earth luminous using visible light photoactivated near-infrared-neodymium bimetallic coordination polymer and its preparation method and application
CN106866990B (en) * 2017-02-15 2019-06-21 中国科学院福建物质结构研究所 A kind of ruthenium coordination polymer with visible light catalytic reduction of CO2 performance and preparation method and use thereof
CN113461956B (en) * 2021-05-31 2022-12-30 广东工业大学 Ruthenium polymer, preparation method thereof and pH value detection fluorescent probe

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5660991A (en) * 1994-10-28 1997-08-26 Lakowicz; Joseph R. Long lifetime anisotropy (polarization) probes for clinical chemistry, immunoassays, affinity assays and biomedical research
WO2000047693A1 (en) * 1999-02-12 2000-08-17 Ljl Biosystems, Inc. Luminescent metal-ligand complexes
US6180354B1 (en) * 1991-05-22 2001-01-30 Dade Behring Marburg Gmbh Metal chelate containing compositions for use in chemiluminescent assays

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6180354B1 (en) * 1991-05-22 2001-01-30 Dade Behring Marburg Gmbh Metal chelate containing compositions for use in chemiluminescent assays
US5660991A (en) * 1994-10-28 1997-08-26 Lakowicz; Joseph R. Long lifetime anisotropy (polarization) probes for clinical chemistry, immunoassays, affinity assays and biomedical research
WO2000047693A1 (en) * 1999-02-12 2000-08-17 Ljl Biosystems, Inc. Luminescent metal-ligand complexes

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BLAKLEY ET AL.: "Unique spectroscopic properties of mixed-ligand-complexes with 2,2'-dipyridylamine: a dual luminescence from a ruthenium(II) complex", JOURNAL OF AMERICAN CHEMICAL SOCIETY, vol. 109, no. 16, 5 August 1987 (1987-08-05), pages 4895 - 4901, XP002939555 *

Also Published As

Publication number Publication date
WO2001032665A2 (en) 2001-05-10
AU3791301A (en) 2001-05-14

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