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WO2000045832A3 - Regulation of anaesthesia - Google Patents

Regulation of anaesthesia Download PDF

Info

Publication number
WO2000045832A3
WO2000045832A3 PCT/GB2000/000281 GB0000281W WO0045832A3 WO 2000045832 A3 WO2000045832 A3 WO 2000045832A3 GB 0000281 W GB0000281 W GB 0000281W WO 0045832 A3 WO0045832 A3 WO 0045832A3
Authority
WO
WIPO (PCT)
Prior art keywords
anaesthesia
subject
regulation
delta
inducing peptide
Prior art date
Application number
PCT/GB2000/000281
Other languages
French (fr)
Other versions
WO2000045832A2 (en
Inventor
Christopher John Doug Pomfrett
Michael Alkire
Richard Haier
Jim Fallon
Original Assignee
Univ Manchester
Christopher John Doug Pomfrett
Michael Alkire
Richard Haier
Jim Fallon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9902469.7A external-priority patent/GB9902469D0/en
Priority to APAP/P/2001/002245A priority Critical patent/AP2001002245A0/en
Priority to IL14457200A priority patent/IL144572A0/en
Priority to MXPA01007949A priority patent/MXPA01007949A/en
Priority to BR0008046-2A priority patent/BR0008046A/en
Priority to JP2000596951A priority patent/JP2002536337A/en
Application filed by Univ Manchester, Christopher John Doug Pomfrett, Michael Alkire, Richard Haier, Jim Fallon filed Critical Univ Manchester
Priority to EA200100861A priority patent/EA200100861A1/en
Priority to KR1020017009855A priority patent/KR20010101992A/en
Priority to CA002360124A priority patent/CA2360124A1/en
Priority to AU24459/00A priority patent/AU2445900A/en
Priority to EP00902714A priority patent/EP1148887A2/en
Publication of WO2000045832A2 publication Critical patent/WO2000045832A2/en
Publication of WO2000045832A3 publication Critical patent/WO2000045832A3/en
Priority to NO20013795A priority patent/NO20013795L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The present invention concerns uses of compounds which modulate Delta-Sleep Inducing Peptide active for regulating anaesthesia and methods of evaluating the anaesthetic needs of a subject comprising assaying a sample taken from the subject for the presence of Delta-Sleep Inducing Peptide.
PCT/GB2000/000281 1999-02-05 2000-02-01 Regulation of anaesthesia WO2000045832A2 (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
EP00902714A EP1148887A2 (en) 1999-02-05 2000-02-01 Regulation of anaesthesia
KR1020017009855A KR20010101992A (en) 1999-02-05 2000-02-01 Regulation of anaesthesia
MXPA01007949A MXPA01007949A (en) 1999-02-05 2000-02-01 Regulation of anaesthesia.
BR0008046-2A BR0008046A (en) 1999-02-05 2000-02-01 Uses of a delta sleep inducing peptide or derivatives and biologically fragments thereof and a compound that decreases the activity of delta sleep inducing peptide and method of assessing the anesthetic needs of an individual to be anesthetized
JP2000596951A JP2002536337A (en) 1999-02-05 2000-02-01 Adjusting anesthesia
APAP/P/2001/002245A AP2001002245A0 (en) 1999-02-05 2000-02-01 Regulation of anesthesia.
EA200100861A EA200100861A1 (en) 1999-02-05 2000-02-01 REGULATION OF ANESTHESIA
IL14457200A IL144572A0 (en) 1999-02-05 2000-02-01 Regulation of anaesthesia
CA002360124A CA2360124A1 (en) 1999-02-05 2000-02-01 Regulation of anaesthesia
AU24459/00A AU2445900A (en) 1999-02-05 2000-02-01 Regulation of anaesthesia
NO20013795A NO20013795L (en) 1999-02-05 2001-08-02 Regulation of anesthesia

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB9902469.7 1999-02-05
GBGB9902469.7A GB9902469D0 (en) 1999-02-05 1999-02-05 Brain metabolism
US12032699P 1999-02-17 1999-02-17
US15566199P 1999-09-24 1999-09-24
US60/120,326 1999-09-24
US60/155,661 1999-09-24

Publications (2)

Publication Number Publication Date
WO2000045832A2 WO2000045832A2 (en) 2000-08-10
WO2000045832A3 true WO2000045832A3 (en) 2000-11-30

Family

ID=27269636

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2000/000281 WO2000045832A2 (en) 1999-02-05 2000-02-01 Regulation of anaesthesia

Country Status (15)

Country Link
EP (1) EP1148887A2 (en)
JP (1) JP2002536337A (en)
KR (1) KR20010101992A (en)
CN (1) CN1346278A (en)
AP (1) AP2001002245A0 (en)
AU (1) AU2445900A (en)
BR (1) BR0008046A (en)
CA (1) CA2360124A1 (en)
ID (1) ID30518A (en)
IL (1) IL144572A0 (en)
MX (1) MXPA01007949A (en)
NO (1) NO20013795L (en)
OA (1) OA11758A (en)
TR (1) TR200102265T2 (en)
WO (1) WO2000045832A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1275308A1 (en) * 2001-07-13 2003-01-15 The Procter & Gamble Company Food composition offering stress relaxation to mammals
JP2010539071A (en) * 2007-09-11 2010-12-16 モンドバイオテック ラボラトリーズ アクチエンゲゼルシャフト Use of a peptide combination of thymosin β4 and a delta sleep-inducing peptide as a therapeutic agent
GB201116271D0 (en) * 2011-09-21 2011-11-02 Univ Cardiff Dispersion anaesthetic device
CN108376559B (en) * 2018-02-28 2020-10-16 复旦大学附属中山医院 Application of acetaldehyde dehydrogenase 2 genotype in the calculation of anesthesia dose
CN112535727A (en) * 2020-12-24 2021-03-23 安域生物制药(杭州)有限公司 Short peptide gel with sleep improvement effect and preparation method thereof
CN112908454B (en) * 2021-02-26 2023-08-29 西安交通大学口腔医院 Method and system for intelligently keeping anesthetic

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4165312A (en) * 1977-06-30 1979-08-21 Hoffmann-La Roche Inc. Phosphorylated nonapeptides, processes for the preparation thereof and pharmaceutical compositions containing them
US4444758A (en) * 1981-05-21 1984-04-24 Hoffmann-La Roche Inc. Nonapeptide for treating addictive drug withdrawal conditions
EP0513702A2 (en) * 1991-05-13 1992-11-19 I.F.L.O. ISTITUTO FARMACOLOGICO LOMBARDO S.A.S. di Giorgio & Aldo Laguzzi & C. Melatonin derivaties for use in the therapy of sleep disorders and in pre-anaesthetic medication
RU2104717C1 (en) * 1995-07-07 1998-02-20 Новокузнецкий государственный институт усовершенствования врачей Method of applying anesthesia when operating on patients with leriche's syndrome

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4165312A (en) * 1977-06-30 1979-08-21 Hoffmann-La Roche Inc. Phosphorylated nonapeptides, processes for the preparation thereof and pharmaceutical compositions containing them
US4444758A (en) * 1981-05-21 1984-04-24 Hoffmann-La Roche Inc. Nonapeptide for treating addictive drug withdrawal conditions
EP0513702A2 (en) * 1991-05-13 1992-11-19 I.F.L.O. ISTITUTO FARMACOLOGICO LOMBARDO S.A.S. di Giorgio & Aldo Laguzzi & C. Melatonin derivaties for use in the therapy of sleep disorders and in pre-anaesthetic medication
RU2104717C1 (en) * 1995-07-07 1998-02-20 Новокузнецкий государственный институт усовершенствования врачей Method of applying anesthesia when operating on patients with leriche's syndrome

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1991, SUDAKOV K V: "ANTISTRESS EFFECTS OF DELTA-SLEEP INDUCING PEPTIDE", XP002146452, Database accession no. PREV199294101504 *
DATABASE WPI Section Ch Week 199840, Derwent World Patents Index; Class B04, AN 1998-465470, XP002146453 *
FIZIOLOGICHESKII ZHURNAL SSSR IMENI I M SECHENOVA, vol. 77, no. 3, 1991, pages 1 - 13, ISSN: 0015-329X *

Also Published As

Publication number Publication date
KR20010101992A (en) 2001-11-15
BR0008046A (en) 2001-11-06
NO20013795D0 (en) 2001-08-02
WO2000045832A2 (en) 2000-08-10
ID30518A (en) 2001-12-13
NO20013795L (en) 2001-08-02
AP2001002245A0 (en) 2001-09-30
OA11758A (en) 2005-07-19
CN1346278A (en) 2002-04-24
TR200102265T2 (en) 2001-12-21
CA2360124A1 (en) 2000-08-10
JP2002536337A (en) 2002-10-29
EP1148887A2 (en) 2001-10-31
IL144572A0 (en) 2002-05-23
AU2445900A (en) 2000-08-25
MXPA01007949A (en) 2003-06-04

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