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WO2000027339A2 - Procede et appareil pour nettoyer des tissus vivants - Google Patents

Procede et appareil pour nettoyer des tissus vivants Download PDF

Info

Publication number
WO2000027339A2
WO2000027339A2 PCT/IL1999/000599 IL9900599W WO0027339A2 WO 2000027339 A2 WO2000027339 A2 WO 2000027339A2 IL 9900599 W IL9900599 W IL 9900599W WO 0027339 A2 WO0027339 A2 WO 0027339A2
Authority
WO
WIPO (PCT)
Prior art keywords
gas
liquid
outflow
oxygen
delivery head
Prior art date
Application number
PCT/IL1999/000599
Other languages
English (en)
Other versions
WO2000027339A3 (fr
Inventor
Michael Tavger
Original Assignee
Tav Tech Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tav Tech Ltd. filed Critical Tav Tech Ltd.
Priority to AU10728/00A priority Critical patent/AU1072800A/en
Publication of WO2000027339A2 publication Critical patent/WO2000027339A2/fr
Publication of WO2000027339A3 publication Critical patent/WO2000027339A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/06—Sprayers or atomisers specially adapted for therapeutic purposes of the injector type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/71—Suction drainage systems
    • A61M1/77—Suction-irrigation systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/84—Drainage tubes; Aspiration tips
    • A61M1/85—Drainage tubes; Aspiration tips with gas or fluid supply means, e.g. for supplying rinsing fluids or anticoagulants
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
    • B05B7/02—Spray pistols; Apparatus for discharge
    • B05B7/04—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge
    • B05B7/0416—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge with arrangements for mixing one gas and one liquid
    • B05B7/0441—Spray pistols; Apparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge with arrangements for mixing one gas and one liquid with one inner conduit of liquid surrounded by an external conduit of gas upstream the mixing chamber
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
    • B05B7/02—Spray pistols; Apparatus for discharge
    • B05B7/12—Spray pistols; Apparatus for discharge designed to control volume of flow, e.g. with adjustable passages

Definitions

  • the present invention relates to the treatment of living tissue, in general, and to the cleansing of exposed living tissue, in particular.
  • the cleansing of exposed in vivo tissue requires the removal from the tissue of inorganic matter, such as fibers, dust, sand particles, and the like, and organic matter, such as pus, fats, and so on.
  • inorganic matter such as fibers, dust, sand particles, and the like
  • organic matter such as pus, fats, and so on.
  • inorganic matter may be cleansed from the tissue by means of a liquid stream, it is often not possible to remove some of the organic matter from the tissue in this manner. More specifically, and most problematic, are those particles which are smaller than the thickness of the boundary layer of the fluid stream which is formed on the tissue; the boundary layer being characterized by having a fluid velocity which reduces sharply adjacent to the flow surface, and which is zero at the surface.
  • the present invention seeks to provide a method of and apparatus for cleansing living tissue, such as during surgical procedures on humans and animals, and which overcome disadvantages of known art
  • the cleansing is performed while using relatively small amounts of liquid, thereby being not only more efficient and less wasteful than known methods, but also being more convenient and less messy to use than known methods
  • the cleansing may be performed utilizing sterile liquids contained in a ste ⁇ le receptacle wherein the sterile liquid thus contained was filled under sterile conditions such that the sterility of the liquid thus contained and used for the cleansing is maintained at the high degree of sterility that is commonly found in operating facilities world-wide
  • the method of the invention is further characterized by having a therapeutic effect on the tissue being cleansed, thereby to accelerate its healing
  • an apparatus for cleansing living tissue which includes a source of a sterile liquid which is maintained substantially at atmospheric pressure, a source of pressurized gas, apparatus having a liquid entry port, and a gas entry port, a gas conduit extending between a gas inlet and a gas outlet, wherein the gas inlet is connected to the source of pressurized gas, and the gas conduit is connected to the source via a gas outlet port, and the gas outlet is connected to the gas entry port of the fluid delivery head, a liquid conduit extending between a liquid inlet arranged in fluid flow communication with the liquid source, and a liquid outlet, and wherein the liquid outlet is connected to the liquid entry port of the fluid delivery head and the liquid conduit is in fluid flow communication with the gas outlet port a valve device located between the entry ports and the fluid outlet for selectively permitting gas flow from the entry ports to the fluid outlet wherein the valve device is movable between first and second operative positions, and wherein, in the first position, the valve is operative
  • the gas flow exits the valve device into the gas-liquid combining member at a pressure of a first magnitude
  • the combining member is operative to cause a pressure drop in the gas flow therethrough such that the pressure of the gas-liquid outflow downstream of the fluid outlet, is of a second magnitude
  • the first magnitude is at least twice the second magnitude, so as to cause a shock wave in the gas-liquid flow downstream of the fluid outlet and fragmentation of the liquid portion of the outflow into microscopic droplets, thereby to form a mist suspended in the gas portion of the outflow
  • the gas inlet of the gas conduit is constructed for connection to a pressurized oxygen source, and the outflow is an outflow of the sterile liquid mist suspended in a high velocity oxygen stream
  • the fluid outlet apparatus further includes an interior gas-liquid combining member arranged to provide an outflow of sterile liquid
  • the gas-liquid combining member includes a rear portion configured to fit over the interior gas-liquid combining member and arranged to fit over the interior gas-liquid combining member so as to define a passageway therebetween for the gas flow, a front portion defining an opening, wherein the passageway is stepped so as to be increasingly constricted towards the front portion of the gas-liquid combining member, such that the gas flow passing through the passageway is accelerated to at least sonic velocity, and wherein the front portion widens towards the opening thereof such that the accelerated gas flow expands and thus undergoes a drop to a pressure which is sub-atmospheric, such that, when the gas-liquid combining member opening is brought to within a predetermined distance to tissue contaminated by pollutant particles, the particles are exposed to the sub-atmospheric pressure so as to be loosened thereby from the tissue
  • a suction conduit extending between a suction source end and a suction entry port end, wherein the suction source end is connected to a source of vacuum suction and the suction entry port end is connected to the suction entry port of the fluid delivery head, such that the fluid outlet has at least two chambers, of differing sizes, a larger chamber being constructed in such a manner such that it is configured to fit over the fluid delivery head, and a smaller chamber so configured as to contain a channel, following from and contiguous with the suction conduit entry port such that the gas-liquid outflow mist, having been discharged from the fluid outlet and now existing as a mixture of liquid and cleansed contaminant particles removed from tissue treated by and exposed to the mist traveling at supersonic speed, can be retrieved by this fluid delivery head and the mixture can be delivered via the suction conduit to a receptacle maintained for the purpose of gathering the mixture and retaining it so that it can be properly and sanitarily disposed of
  • a method of cleansing living tissue which includes exposing a source of ste ⁇ le liquid to a flow of pressurized gas, thereby to cause a drawn supply thereof into a fluid delivery head, supplying the pressurized gas to the fluid delivery head, combining the gas and liquid supplied to the fluid delivery head so as to provide a gas-liquid outflow in the form of a sterile liquid mist suspended in a high velocity gas stream, and exposing the living tissue to the gas-liquid outflow, thereby to loosen and remove therefrom contaminant particles, and exposing the gas-liquid outflow, now consisting of a mixture of liquid and cleansed contaminant particles, which are no longer attached to living tissue, to a suction force whereby the mixture is removed from the treatment site, so as to facilitate the complete removal of the contaminant particles from the living organism, such that they will not inadvertently be re-introduced into another area of the living organism being treated and such that the contaminant particles
  • the step of supplying the pressurized gas includes supplying the gas at a pressure of a first magnitude
  • the step of combining includes causing a pressure drop in the gas flow such that the pressure of the gas-liquid outflow, is of a second magnitude, wherein the first magnitude is at least twice the second magnitude, so as to cause a shock wave in the gas-liquid outflow and fragmentation of the liquid portion of the outflow into microscopic droplets, thereby to form a mist suspended in the gas portion of the outflow
  • a method of cleansing and healing damaged living tissue which includes exposing a source of sterile liquid to a flow of pressurized oxygen, thereby to cause a drawn supply thereof into a fluid delivery head, supplying the pressurized oxygen to the fluid delivery head, combining the oxygen and liquid supplied to the fluid delivery head so as to provide an oxygen-liquid outflow in the form of a sterile liquid mist suspended in a high velocity oxygen stream, and exposing the damaged tissue to the oxygen-liquid outflow thereby to remove therefrom contaminants and heal the damaged tissue
  • the step of supplying the pressurized oxygen comprises supplying the oxygen at a pressure of a first magnitude
  • the step of combining includes causing a pressure drop in the oxygen flow such that the pressure of the oxygen-liquid outflow, is of a second magnitude, wherein the first magnitude is at least twice the second magnitude, so as to cause a shock wave in the oxygen-liquid outflow and fragmentation of the liquid portion of the outflow into microscopic droplets, thereby to form a mist suspended in the oxygen portion of the outflow
  • the oxygen-liquid outflow has a near-sonic velocity
  • Fig 1 is a general view of the cleansing apparatus constructed and operative in accordance with a preferred embodiment of the present invention
  • Fig 2 is a diagrammatic representation of a handpiece constructed in accordance with a preferred embodiment of the invention.
  • Fig 3 is a partial side view of the handpiece of Fig 2
  • Fig 4A is an enlarged, cut-away view of the fluid delivery head
  • Fig 4B is an enlarged, exploded view of the fluid delivery head
  • Fig 5 is an enlarged, cut-away view of the gas-liquid mixing member of the fluid delivery head
  • Fig 6 is an enlarged cross-sectional view of the circled area in Fig 5 indicated by arrow 6 therein,
  • Fig 7 is a cutaway view of the rear-portion and mid-section of the handpiece showing the valve assembly and the gas flow channel
  • Fig 8A is an enlarged cross-sectional view of the valve seen in Fig 7, taken along line 8-8 therein, seen in an open position, and
  • Fig 8B is an enlarged cross-sectional view of the valve seen in Fig 7, taken along line 8-8 therein, seen in a closed position DETAILED DESCRIPTION OF A PREFERRED EMBODIMENT
  • the present invention provides apparatus, referenced generally 1 1 which employs a liquid and a gas as working fluids for cleansing living tissue, such as human or animal tissue during surgical procedures
  • a liquid and a gas as working fluids for cleansing living tissue, such as human or animal tissue during surgical procedures
  • Apparatus 11 includes a handpiece, reference generally 414, which includes a fluid delivery head 314, midsection 416, and rear portion 404 Rear portion 404, at end 378 thereof, is connected to sources of liquid and gas, respectively referenced 41 and 35, and is operative to combine these working fluids into a gas-liquid mist for cleansing living tissue, as described
  • Apparatus 11 includes a liquid conduit 56 having an inlet end 59 for accessing a source 41 of sterile liquid in a receptacle suitable for this purpose, such as the disposable polyethylene ones commonly used for containing intravenous solutions in hospital settings, well known and found in use in operating suites and hospital facilities world-wide
  • a source 41 of sterile liquid in a receptacle suitable for this purpose such as the disposable polyethylene ones commonly used for containing intravenous solutions in hospital settings, well known and found in use in operating suites and hospital facilities world-wide
  • This source 41 contains a supply of a sterile liquid, such as any suitable saline solution, for example, a 0 9% sodium chloride solution suitable for irrigation
  • Liquid conduit 56 is connected to liquid source 41 via connector means 57 such as a standard hollow spike valve needle connector of the type prevalent in the art of current medical practice
  • Apparatus 11 also includes a gas conduit 34 which has an inlet end 36, which is preferably removably coupled via an oxygen plug 38 to an oxygen outlet 40, together defining a connection such as the "Ohmeda TM-Style Quick-Connect NPT" oxygen connection, well known and found in many hospitals in the United States and worldwide, and which has associated therewith a central, high pressure oxygen supply
  • the gas supply has a generally steady, non-pulsating pressure head, of approximately 2-3 atm
  • the handpiece 414 is also provided with a suction flow conduit 53, via which tissue contaminants and fluid are drawn away from living tissue and are passed to a container (not shown) for subsequent storage and disposal
  • liquid conduit 56 is attached, by a suitable coupling 363, to a liquid entry port 362 of liquid conduit 386
  • the gas conduit 34 is attached, by a suitable coupling 374, to a gas entry port 360 of gas conduit 376 Liquid and gas pass, from respective conduits 386 and 376, via respective outlets 354 and 370, to a gas-liquid combining member 276, whereat the gas and liquid are combined to produce a mist
  • This mist is delivered at near sonic velocity, as described below, to a fluid outlet port 272
  • a suction channel 256 whose purpose will be described below
  • fluid delivery head 314 is provided with a combining member 276, within which the gas and liquid are combined to form a fluid, as described below
  • Combining member 276 includes a recessed portion 277, which is formed so as to cause a central conversion of the gas throughflow in head 314 towards the liquid emerging from the liquid conduit 386
  • Liquid exiting outlet 354 of conduit 386 flows through a needle-like liquid flow outlet bore 284 into gas-liquid combining member 276
  • Gas exiting outlet 370 enters an annular passageway 380 of gas-liquid combining member 276 via an entrance conduit 316
  • the gas flowing along passageway 380 accelerates from a sub-sonic velocity to a sonic velocity, and then further accelerates to supersonic velocity at the end 410 of passageway 380
  • the expansion wave thus generated undergoes a considerable pressure drop, to at least sub-atmospheric pressure, thereby
  • the fluid delivery head 314 is constructed so as to minimize such head loss, and so as to ensure that the fluid pressure remains in excess of 2 atm, until the point at which the fluid jet emerges through opening 312 of combining chamber 276 While the area of the fluid delivery head 314 is in equilibrium with the ambient atmosphere, with regard to pressure, the velocity of the fluid jet which emerges therefrom approximates the velocity of sound, namely, 330 m/s
  • handpiece 414 includes a valve assembly, referenced generally 372, which facilitates passage of liquid and gas, respectively, from liquid entry port 362 and gas entry port 360, into gas-liquid combining member 276
  • Valve assembly 372 includes a gas supply bore 342, which is connected to gas entry port 360
  • Valve assembly 372 is provided with a thumb controlled head portion 271 , that extends via a narrow connecting element 336 through bore 342
  • Connecting element 336 includes a broadened portion 332 O- ⁇ ng 330 rests on this broadened portion effectively preventing a throughflow of gas when the valve assembly 372 is in its closed position (Fig 8B)
  • depression of head portion 271 inwards is operative to cause an inward, linear translation of connecting element 336, thereby lowering broadened portion 332, thereby allowing O- ⁇ ng 330 to move away from bore 342, resulting in a partial opening of bore 342 and enabling a flow of gas through the valve assembly 372
  • Release of head portion 271 allows the head portion 271 to move outwardly, resulting in raising of broadened portion 332, thereby causing O- ⁇ ng 330 to move into the path of bore 342, thus preventing the flow of gas therethrough

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Surgery (AREA)
  • Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)

Abstract

Appareil servant à nettoyer des tissus vivants qui comporte : une source de liquide stérile sensiblement maintenu à pression atmosphérique; une source de gaz sous pression; un embout de distribution de fluide comprenant une sortie de fluide; un conduit de gaz reliant une entrée de gaz connectée à la source de gaz sous pression à une sortie de gaz située dans l'embout de distribution de fluide; un conduit de liquide reliant une entrée de liquide disposée de façon à permettre une communication fluidique avec la source de liquide, à une sortie de liquide située dans l'embout de distribution de fluide et disposée de façon à permettre une communication fluidique avec la sortie de gaz; et un obturateur fixé et associé de façon fonctionnelle au conduit de gaz, permettant à un flux gazeux de s'écouler par la sortie de gaz. Cet obturateur peut être déplacé entre une première et une seconde position fonctionnelles. Dans la première position, l'obturateur permet le passage d'un flux gazeux à une pression sous-atmosphérique à grande vitesse, de façon à soumettre la sortie de liquide et par conséquent la source de liquide, à une pression sous-atmosphérique pour envoyer le flux de liquide dans l'embout de distribution de fluide. Dans la deuxième position, l'obturateur arrête sensiblement le passage du flux gazeux pour empêcher que le liquide soit envoyé dans l'embout de distribution de fluide. La sortie de fluide comprend un élément de mélange du gaz et du liquide, disposé de manière à recevoir les flux gazeux et liquide pour les combiner en un flux de sortie de gaz liquide capable de sortir de l'appareil à travers la sortie de fluide sous la forme d'une vapeur liquide stérile en suspension dans un courant gazeux à grande vitesse.
PCT/IL1999/000599 1998-11-08 1999-11-07 Procede et appareil pour nettoyer des tissus vivants WO2000027339A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU10728/00A AU1072800A (en) 1998-11-08 1999-11-07 Apparatus and method for cleansing tissue

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL126950 1998-11-08
IL12695098A IL126950A0 (en) 1998-11-08 1998-11-08 Apparatus and method for cleansing tissue

Publications (2)

Publication Number Publication Date
WO2000027339A2 true WO2000027339A2 (fr) 2000-05-18
WO2000027339A3 WO2000027339A3 (fr) 2000-08-10

Family

ID=11072117

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL1999/000599 WO2000027339A2 (fr) 1998-11-08 1999-11-07 Procede et appareil pour nettoyer des tissus vivants

Country Status (3)

Country Link
AU (1) AU1072800A (fr)
IL (1) IL126950A0 (fr)
WO (1) WO2000027339A2 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002053110A3 (fr) * 2001-01-04 2002-12-05 Beniamino Palmieri Preparation pour lavages internes et/ou irrigations de cavites naturelles ou pathologiques du corps humain
EP2662146A3 (fr) * 2012-05-07 2017-03-08 Heraeus Medical GmbH Système de lavage avec buse
FR3082711A1 (fr) 2018-06-26 2019-12-27 L'oreal Systeme d’injection sans aiguille
FR3111272A1 (fr) 2020-06-16 2021-12-17 L'oreal Dispositif d’injection sans aiguille d’une composition photo-polymérisable

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4350158A (en) * 1980-02-04 1982-09-21 Hudson Raymond A Pulsating spray nozzle
US4982730A (en) * 1988-12-21 1991-01-08 Lewis Jr Royce C Ultrasonic wound cleaning method and apparatus
US5848998A (en) * 1996-07-11 1998-12-15 Marasco, Jr.; Patrick V. Tissue debriding apparatus
US5843052A (en) * 1996-10-04 1998-12-01 Benja-Athon; Anuthep Irrigation kit for application of fluids and chemicals for cleansing and sterilizing wounds
US5735833A (en) * 1996-12-11 1998-04-07 Bristol-Myers Squibb Co. Lavage tip

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002053110A3 (fr) * 2001-01-04 2002-12-05 Beniamino Palmieri Preparation pour lavages internes et/ou irrigations de cavites naturelles ou pathologiques du corps humain
EP2662146A3 (fr) * 2012-05-07 2017-03-08 Heraeus Medical GmbH Système de lavage avec buse
FR3082711A1 (fr) 2018-06-26 2019-12-27 L'oreal Systeme d’injection sans aiguille
WO2020002263A1 (fr) 2018-06-26 2020-01-02 L'oreal Système d'injection sans aiguille
FR3111272A1 (fr) 2020-06-16 2021-12-17 L'oreal Dispositif d’injection sans aiguille d’une composition photo-polymérisable

Also Published As

Publication number Publication date
WO2000027339A3 (fr) 2000-08-10
AU1072800A (en) 2000-05-29
IL126950A0 (en) 1999-09-22

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