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WO1999059810A3 - Microstructured films - Google Patents

Microstructured films Download PDF

Info

Publication number
WO1999059810A3
WO1999059810A3 PCT/EP1999/002971 EP9902971W WO9959810A3 WO 1999059810 A3 WO1999059810 A3 WO 1999059810A3 EP 9902971 W EP9902971 W EP 9902971W WO 9959810 A3 WO9959810 A3 WO 9959810A3
Authority
WO
WIPO (PCT)
Prior art keywords
film
microchannels
microchannel
cover layers
seal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP1999/002971
Other languages
German (de)
French (fr)
Other versions
WO1999059810A2 (en
Inventor
Frank Krause
Heinz Linder
Franz Schmitt
Georg Wiessmeier
Hansjoerg Duerr
Karsten Dierksen
Simone Greven
Klaus Heidenreich
Peter Jaehn
Juergen Klein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to AU40358/99A priority Critical patent/AU4035899A/en
Application filed by Bayer AG filed Critical Bayer AG
Priority to EP99923506A priority patent/EP1079928A2/en
Priority to JP2000549457A priority patent/JP2002515351A/en
Publication of WO1999059810A2 publication Critical patent/WO1999059810A2/en
Publication of WO1999059810A3 publication Critical patent/WO1999059810A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F28—HEAT EXCHANGE IN GENERAL
    • F28D—HEAT-EXCHANGE APPARATUS, NOT PROVIDED FOR IN ANOTHER SUBCLASS, IN WHICH THE HEAT-EXCHANGE MEDIA DO NOT COME INTO DIRECT CONTACT
    • F28D9/00—Heat-exchange apparatus having stationary plate-like or laminated conduit assemblies for both heat-exchange media, the media being in contact with different sides of a conduit wall
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/06—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material
    • B32B27/08—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0689—Sealing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/12—Specific details about manufacturing devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F28—HEAT EXCHANGE IN GENERAL
    • F28F—DETAILS OF HEAT-EXCHANGE AND HEAT-TRANSFER APPARATUS, OF GENERAL APPLICATION
    • F28F2260/00—Heat exchangers or heat exchange elements having special size, e.g. microstructures
    • F28F2260/02—Heat exchangers or heat exchange elements having special size, e.g. microstructures having microchannels
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F28—HEAT EXCHANGE IN GENERAL
    • F28F—DETAILS OF HEAT-EXCHANGE AND HEAT-TRANSFER APPARATUS, OF GENERAL APPLICATION
    • F28F2275/00—Fastening; Joining
    • F28F2275/06—Fastening; Joining by welding
    • F28F2275/065—Fastening; Joining by welding by ultrasonic or vibration welding

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Mechanical Engineering (AREA)
  • Dispersion Chemistry (AREA)
  • Thermal Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Lining Or Joining Of Plastics Or The Like (AREA)
  • Rigid Pipes And Flexible Pipes (AREA)
  • Heat-Exchange Devices With Radiators And Conduit Assemblies (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Laminated Bodies (AREA)

Abstract

The invention relates to a module consisting of polymer materials and containing chosen microchannel systems, and to a method for producing a module of this type. The inventive model with microchannels consists of a polymer film (2) whose thickness corresponds to the desired channel depth, with recesses (1) in the shape of the desired microchannel structure. An upper (4) and a lower (3) cover layer provide a seal for this microstructured film on both sides. The cover layers are planar on the side facing towards the structured film and form the top and bottom surfaces of the channels. At least one of the two cover layers has at least two entrances (5) to the microchannel system in the microstructured film. The inventive method for producing a module consisting of polymer materials and containing microchannel systems comprises the structuring of one or several films with the microchannels and connecting one film with the two cover layers in order to seal the microchannels.
PCT/EP1999/002971 1998-05-14 1999-05-03 Microstructured films Ceased WO1999059810A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU40358/99A AU4035899A (en) 1998-05-14 1999-04-21 Microstructured films
EP99923506A EP1079928A2 (en) 1998-05-14 1999-05-03 Microstructured films
JP2000549457A JP2002515351A (en) 1998-05-14 1999-05-03 Microstructured film

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE1998121627 DE19821627A1 (en) 1998-05-14 1998-05-14 Module with microchannel system useful in miniaturized processing or analysis systems e.g. PCR or immunoassays
DE19821627.0 1998-05-14

Publications (2)

Publication Number Publication Date
WO1999059810A2 WO1999059810A2 (en) 1999-11-25
WO1999059810A3 true WO1999059810A3 (en) 2000-03-16

Family

ID=7867754

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1999/002971 Ceased WO1999059810A2 (en) 1998-05-14 1999-05-03 Microstructured films

Country Status (5)

Country Link
EP (1) EP1079928A2 (en)
JP (1) JP2002515351A (en)
AU (1) AU4035899A (en)
DE (1) DE19821627A1 (en)
WO (1) WO1999059810A2 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1320712B1 (en) 2000-07-28 2006-10-11 Honda Giken Kogyo Kabushiki Kaisha Multi-purpose microchannel micro-component
JP2002174610A (en) * 2000-12-08 2002-06-21 Nec Corp Biosensor and liquid sample measurement method using biosensor
GB2372464B (en) * 2001-02-22 2003-05-14 Vivascience Ltd Method of isolating a charged compound
GB0126281D0 (en) * 2001-11-01 2002-01-02 Astrazeneca Ab A chemical reactor
AU2003235970A1 (en) * 2002-04-30 2003-11-17 Arkray, Inc. Analysis instrument, sample analysis method and analysis device using the instrument, and method of forming opening in the instrument
US7279134B2 (en) * 2002-09-17 2007-10-09 Intel Corporation Microfluidic devices with porous membranes for molecular sieving, metering, and separations
JP4683538B2 (en) * 2004-05-06 2011-05-18 セイコーインスツル株式会社 Analysis system and analysis method including microchip for analysis
DE102005007707A1 (en) * 2004-09-27 2006-03-30 Powerfluid Gmbh Recuperator, microchannel recuperator, foil, use of a film and method for producing and operating a recuperator
CN101263077B (en) * 2005-09-09 2011-11-09 皇家飞利浦电子股份有限公司 A method of manufacturing a microsystem with interval
DE102006010956A1 (en) * 2006-03-06 2007-09-13 Directif Gmbh Valve for use in micro-fluidic system, has flexible diaphragm arranged such it is pressed in concave recess using pressure exerting unit and is fixed at distance to recess on support rising against surface of carrier
EP2800187B1 (en) * 2007-03-21 2017-12-20 Intelligent Energy Limited Electrochemical system comprising a fluid manifold
US8133629B2 (en) 2007-03-21 2012-03-13 SOCIéTé BIC Fluidic distribution system and related methods
DE102008051091B3 (en) 2008-10-09 2010-06-10 Bleckmann Gmbh & Co. Kg Plate heat exchanger and an arrangement of such and a fluid heating
JP5892551B2 (en) * 2010-06-30 2016-03-23 株式会社メタボスクリーン Microchemical chip, method for producing the same, and method for using the same
JP6057166B2 (en) * 2013-01-18 2017-01-11 大日本印刷株式会社 Structure, method for manufacturing structure, and method for manufacturing molded article
JP5685630B2 (en) * 2013-07-19 2015-03-18 Ｊｆｅエンジニアリング株式会社 Microchip
CN111282607B (en) 2015-01-14 2023-03-28 彼克斯赛尔医疗科技有限公司 Disposable cartridge for sample fluid analysis
DE102018003495B4 (en) * 2018-04-30 2020-10-22 I.G. Bauerhin Gmbh Seat occupancy detection element

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2184536A1 (en) * 1972-05-19 1973-12-28 Anvar Very low temperature heat exchangers - partic suitable for helium 3 and helium 4
US5250263A (en) * 1990-11-01 1993-10-05 Ciba-Geigy Corporation Apparatus for processing or preparing liquid samples for chemical analysis
US5500071A (en) * 1994-10-19 1996-03-19 Hewlett-Packard Company Miniaturized planar columns in novel support media for liquid phase analysis
DE19652823A1 (en) * 1996-12-18 1998-03-26 Guenter Prof Dr Fuhr Three dimension micro-system spacers

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2184536A1 (en) * 1972-05-19 1973-12-28 Anvar Very low temperature heat exchangers - partic suitable for helium 3 and helium 4
US5250263A (en) * 1990-11-01 1993-10-05 Ciba-Geigy Corporation Apparatus for processing or preparing liquid samples for chemical analysis
US5500071A (en) * 1994-10-19 1996-03-19 Hewlett-Packard Company Miniaturized planar columns in novel support media for liquid phase analysis
DE19652823A1 (en) * 1996-12-18 1998-03-26 Guenter Prof Dr Fuhr Three dimension micro-system spacers

Also Published As

Publication number Publication date
AU4035899A (en) 1999-12-06
EP1079928A2 (en) 2001-03-07
WO1999059810A2 (en) 1999-11-25
JP2002515351A (en) 2002-05-28
DE19821627A1 (en) 1999-11-18

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