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WO1994014488A1 - Equipement doseur et producteur d'une action d'aspiration-impulsion, applicable a la phlebologie et autres applications medicales - Google Patents

Equipement doseur et producteur d'une action d'aspiration-impulsion, applicable a la phlebologie et autres applications medicales Download PDF

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Publication number
WO1994014488A1
WO1994014488A1 PCT/ES1993/000101 ES9300101W WO9414488A1 WO 1994014488 A1 WO1994014488 A1 WO 1994014488A1 ES 9300101 W ES9300101 W ES 9300101W WO 9414488 A1 WO9414488 A1 WO 9414488A1
Authority
WO
WIPO (PCT)
Prior art keywords
syringe
phlebology
suction
producing
medical uses
Prior art date
Application number
PCT/ES1993/000101
Other languages
English (en)
Spanish (es)
Inventor
Miguel Angel Gramajo Booth
Original Assignee
Miguel Angel Gramajo Booth
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miguel Angel Gramajo Booth filed Critical Miguel Angel Gramajo Booth
Publication of WO1994014488A1 publication Critical patent/WO1994014488A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/1456—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons with a replaceable reservoir comprising a piston rod to be moved into the reservoir, e.g. the piston rod is part of the removable reservoir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/15003—Source of blood for venous or arterial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150229—Pumps for assisting the blood sampling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150244—Rods for actuating or driving the piston, i.e. the cylindrical body that sits inside the syringe barrel, typically with an air tight seal, and slides in the barrel to create a vacuum or to expel blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150992—Blood sampling from a fluid line external to a patient, such as a catheter line, combined with an infusion line; Blood sampling from indwelling needle sets, e.g. sealable ports, luer couplings or valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2209/00—Ancillary equipment
    • A61M2209/01—Remote controllers for specific apparatus

Definitions

  • the present invention is related to medical instruments in general, and more particularly it relates to equipment capable of generating an aspiration-impending action through a tube and a hypodermic needle, and of conveniently dosing said action, being fundamentally applicable in the field of phlebology, but also in other medical uses where similar benefits are required.
  • the apparatus that comprises it has been specifically designed to suck and inject liquids, - and its immediate application is essentially related to the field of sclerosing therapy of varicose veins; although, equally, it can be used in all precision work that requires the location and / or injection of blood or lymphatic vessels.
  • hypodermic syringes are used, particularly used in sclerosing therapy, which constitutes 70% of the specialist's effective working time.
  • hypodermic syringe created by Rynd in 1985
  • the invention referred to in the present specification provides an ingenious and simple solution to the problems posed, providing an ingenious and simple solution to the problems raised, providing an apparatus specifically designed for the work of venous sclero therapy, this It is, for the introduction of sclerosing substances in varicose veins.
  • This electromechanical device through a tube or conduction exerts an aspirating and impending action of instantaneous action.
  • the distal end of said tube or conduit is provided with a hypodermic needle, supported by an anatomically designed handle.
  • the device is operated remotely from a pedal or a drive means provided by said anatomical handle, by electrical impulse from the device or by remote control.
  • the substance to be impelled is contained in hypodermic syringes of any size or in any container, bottle, vial, test tube, etc.
  • the mechanism of the suction-impellent action is carried out through the actuation, already of a peristatic pump with bidirectional rotation movement, and of the bidirectional movement of the piston corresponding to a syringe.
  • said piston can be moved by mechanical action of an auger connected to a rotation motor and integral with the piston, or by direct pressure of the piston through a mechanism that has positive or negative pneumatic or hydraulic pressure.
  • One of the characteristics of the operation is that as soon as it is injected, even if the tube or conduction remains with residual pressure, when the cuttings are automatically interrupted, 1 leakage of the liquid, without giving rise to dripping, that is, that the tube can, if desired , to be perfectly purged (without air) before and after its impending action, and without residual pressure in the system since it would cause an unwanted ejection effect or incompatible with certain uses ("ready for action" function).
  • aeration means is provided in the peristaltic pump system for the relief of pressure in the tube or conduit, while for the use of a hypodermic syringe the presence of a means of instantaneous release of the pressure on the plunger.
  • This device has a control panel that includes function indicator displays, being able to regulate the force or pressure of the aspirant-impeller action, program the quantity of liquid to be ejected or aspirate, with automatic cutting, and register the quantity of ejected liquid, the one that is still in the container, and even the one that was programmed to inject or aspirate.
  • the device can also have an automatic and variable sound signal (beep), according to the program, to warn when the passage of a certain amount of liquid occurs.
  • Figure 1. It shows a schematic view of the device, allowing to appreciate its general constitution and arrangement of the different parts that comprise it, observing the presence of the syringe, the means of actuation of the same, the pedal remote control, the tube or conduit and, at its tip, the anatomical handle, in arrangement as shown, or also, in an inverted position to that shown, depending on the operator's work method.
  • Figure 1-A Shows, according to a representation similar to that of Figure 1, a variant embodiment in which the syringe is external to the housing of the drive group.
  • Figure 2.- Shows a schematic view of a possible control panel.
  • Figure 3. Shows a diagram of the syringe drive system through a pneumatic circuit.
  • FIG. 3-A Shows a schematic view of the control pedal, and its alternative actuation possibilities to produce aspiration and infusion, respectively.
  • Figure 4.- Shows an infusion flow diagram of the pneumatic system.
  • Figure 5. Shows a diagram corresponding to the pneumatic suction system.
  • Figure 6 It shows another embodiment of the device shown schematically, in which the drive means is electromechanical.
  • FIG. 6-A Shows a schematic view of the control pedal of the device, with reference to Figure 6.
  • Figure 7.- Shows a flow chart corresponding to the infusion system by electromechanical drive.
  • Figure 8. Shows an operative diagram of the device applied to the technique aimed at locating the vein.
  • Figure 9. Shows another operative diagram of the device, intended to produce continuous aspiration.
  • Figure 10.- Shows a schematic view of the control panel.
  • Figure 11.- Shows a block diagram of the electronic control circuit associated with the syringe.
  • a receptacle that contains the mechanical and electronic means of the device consisting of: a container such as a vial-ampoule, ampoule, test tube, etc., intended to contain the substance to be injected (eg medicated ).
  • said container consists of the cylinder (1) of a hypodermic syringe (a) forming a chamber of variable capacity which, defined by the relative position within it of a plunger (2) commandable through a rod, by the part opposite ends in a tubular nozzle (3).
  • This nozzle (3) constitutes the coupling point of one of the ends of a flexible and disposable tube or connection (4) whose other end, through the cylinder head (4 ') of an anatomical control handle (e), by a mandrel or the like (6) ends up assembling a needle (7), figure 1.
  • the handle (e) consists of a handle body (5) that has an intermediate bending (5 1 ) and ends at the mandrel end (6). So that by virtue of this intermediate bending (5 ') the handle (e) defines two unaligned sections (5) and (6), which give it an elongated "S" configuration, and thus constitutes an anatomical, adaptable conformation to the concavity of the hand, and that can be taken from (5 ') in the position indicated in figure 1, or in an inverted way, (with the section (6) down) according to the type of work to be done and the modality of the operator.
  • said handle (e) can be formed by two halves connected or hinged to each other, through which the conduit passes, inserted in a nozzle (4 ') of cylinder head and connected at its end to the needle (7) that It is fixed by means of a mandrel or similar.
  • the syringe (a) or, where appropriate, the container used is attached to the body of 1 casing (d) by appropriate means such as clamps, hooks, positional locks, cotters and others that, preferably, enable its removable assembly , by connecting it to an electronic control circuit, which is illustrated in Figure 11, so that it can thus send to this electronic circuit a signal indicative of the size and volume of the syringe (a).
  • the device works with a peristaltic pump (not shown).
  • the same device consists of a driving means formed by a bi-directional cylinder (b), of walls (8) in which a conductive piston (9) is channeled which, through a rod is connected to the plunger ( 2), driven, of the cylindrical (1) corresponding to the syringe (a), and said plunger (9) is, in turn, commanded by a motor means (c) whose body (10) by means of an endless screw (s) ) or other appropriate means commands said driving piston (9), the motor means being connected by (11) to the body (12) of a pedal (f) intended to remotely command the device.
  • command can also be located in the handle itself (e), by one or more pushbuttons operable by the operator's own hand that controls the needle (7) from said handle (e).
  • the screw is connected to an impeller, preferably constituted by the electric motor (c) step by step (in other figures identified as M) that move said screw in a controlled manner and, through it, to the piston (2 ) that travels in the longitudinal direction of the syringe (a), figure 1.
  • an impeller preferably constituted by the electric motor (c) step by step (in other figures identified as M) that move said screw in a controlled manner and, through it, to the piston (2 ) that travels in the longitudinal direction of the syringe (a), figure 1.
  • the stepper motor (M) has a plurality of connections (14) through which an electronic control circuit is connected, as illustrated in the diagram in Figure 11.
  • an electronic control circuit For the purpose of which the operator must not take their hands for other tasks than those of properly inserting the needle (7) in the vessel and provide 'the drug is provided with an external control (20) constituted preferably by a pedal (f) which, through the electronic control circuit performs the tasks of blood aspiration (to determine if the end of the needle is correctly positioned within the vein) as well as the subsequent injection of the medication (figures 11 and 12).
  • the piston (9) of the cylinder (b), Figure 3 is driven by a pneumatic circuit comprising the pneumatic pump (B), which commands the electro-pneumatic valves (VI) and (V2) three-way, as well as a two-way valve (V3), so that, in response to the command of the pedal (f), or of the handle switch (e), if applicable, they are enabled according to the position of said pedal or said switch: in position (NI) which corresponds to the infusion drive, and (N2) corresponding to the suction drive (figures 3-A and 6-A), having the pedal (f) an intermediate joint from which it is pressed towards one or another function.
  • NI which corresponds to the infusion drive
  • N2 corresponding to the suction drive
  • the flow chart of Figure 4 schematizes the infusion process through the pneumatic circuit.
  • the pump (B) is commanded and, by means of this, the solenoid valve (V2) that presses the driving piston (9) corresponding to the bidirectional cylinder (b) is enabled which, by coupling (R) that links it to the rod of the driven piston (2) in the syringe (a), causes the movement of said piston (2) by expelling the liquid contained by the spout (3) and the conduction ( 4) until reaching the needle (7).
  • the solenoid valve (V2) is deactivated while the (VI) is activated for a certain interval (AT), to subsequently deactivate the pump (B) and said valve (VI).
  • the plunger (9) returns without dragging (2) to conclude the infusion.
  • the solenoid valve (V3) is activated for an interval (AT), after which it is deactivated and the system is aerated.
  • the pedal (f) presses the position (N2) that activates the pump (B) and with it the solenoid valve (VI), which means that the piston (9) moves backwards dragging the plunger (2) ) of the syringe (a), and then giving rise to aspiration.
  • Figure 6 shows an electromechanical command system, also operable from a pedal (f), figure 6-A and whose infusion process is the one represented in the flow chart of figure 7.
  • the keyboard is selected in the keypad (figure 10)
  • the control circuit causes the motor (M) to turn in a direction that will suck blood from the vessel to indicate to the operator that it is inside the vein. Subsequently, when the same pedal (f) is pressed towards its position (NI), the vein injection of the corresponding medicine will instead occur.
  • the syringe (a) may be located outside the housing or receptacle (d), the cylinder (1) of said syringe (a) being conveniently attached to the housing (d) by means of a clamp (16), while another clamp (16 ') relates the plunger (2) of the syringe with an inner nut (17), accessing the inside of the housing (d) through a groove (17 ') operatively practiced therein, which allows the longitudinal displacements of the clamp (16') to drive the plunger (2), said nut (17) being driven longitudinally by an auger (18) mounted on end bushings (18 '), conveniently in solidarity with the housing and collaborating with said nut (17) a guide (19) that immobilizes it in an angular or rotating direction when the auger (18) is driven by the motor (10), which will be assisted by a multiple connector (30) through which it will be connected to the circ electronic control device as illustrated in figures 11 and 12.
  • Two sensors (33) start and end of travel for the nut (17) collaborate in the set, directly driven by the latter in their displacements in either direction.
  • the injection speed, pressure, etc. will be co-controlled by the electronic circuit, and will depend on factors such as the type of medication used, the patient, etc.
  • the electronic circuit comprises a central processing unit (21) connected by means of a group of electrical conductors or bus (29), a memory (22) EPROM, to a memory (23) RAM, a a visual display device (24) or display, and a real time clock circuit (25) which, in turn, is connected to said central processing unit (21) through a second connection line ( 30).
  • central processing unit (21) is connected to an adapter adapter circuit (28) that allows said central processing unit (21) to communicate with external devices such as the syringe sensor
  • the data of different characteristics such as pulses, pulse code, variable voltages, etc., from the keyboard (12), the syringe sensor (27) and the extreme control (20), are conveniently adapted by the interface circuit ( 28), so that the central processing unit (21) interprets and processes said data properly as well as that the information directed towards the stepper motor (M) arrives therein in a manner appropriate to the mode of operation of said motor .
  • the real time clock (25) synchronizes the sequence of operations to be carried out by the central processing unit (21), such as reading the memory (22) EPROM, reading and / or writing the memory (23 ) RAM, and the entry of data to be exposed by the visual presentation device (24).
  • the set of instructions or program (software), to be developed by the central processing unit (21), is stored in the memory (22) EPROM, while the information that will flow from or between external devices, or peripherals, such as the keyboard (26), the syringe sensor (27), the external control (20) , and even the visual display device (24) or display, will be stored in the memory (23) RAM, so that the central processing unit "CPU” (21) together with the memory (22) EPROM and the clock real time (25) process the information received through the interface (28), and represent the data required by the operator on the display (24)
  • FIG. 12 A block scheme equivalent to that shown in Figure 11 is illustrated in Figure 12, but now a microprocessor (31) is shown, which includes the central processing unit (21), the memory (22) EPROM, the memory ( 23) RAM, the real time clock (25) and the interface circuit (28) already illustrated in figure 11. Also including in this figure 12, the step motor (M), the external control (20), the sensor syringe (27), the keyboard. (26), and the display (24), also illustrated in Figure 11, and adding a motor controller circuit (32), these blocks being linked 1 microprocessor (31) by means of the corresponding connection lines, with the exception of the stepper motor (12) shown connected to said motor controller (32).
  • a microprocessor (31) which includes the central processing unit (21), the memory (22) EPROM, the memory ( 23) RAM, the real time clock (25) and the interface circuit (28) already illustrated in figure 11. Also including in this figure 12, the step motor (M), the external control (20), the sensor syringe (27), the keyboard. (26), and the display (24), also illustrated in Figure 11,
  • the microprocessor (31) controls 1 stepper motor (M) through a "drivers" circuit, or drivers, which can be to transistors, which accept in their input lines microprocessor commands (21) and generate the logic of electrical impulses necessary for the movement of the step motor (M), while providing the necessary current
  • the functions performed by the microprocessor (31) are selected through the keyboard (26), which acts directly on terminals of said microprocessor (31), these functions being such as the selection of the speed of the stepper motor (M), variable in predetermined steps: the advance or reverse of said stepper motor (M), the reset of the display (24) and the positioning of the piston (2) corresponding to the syringe (a), figure one.
  • the microprocessor (31) While the display (24) provides as information the volume injected by the syringe (a), and the direction of rotation of the stepper motor (M), the microprocessor (31), through the appropriate program allows to predetermine and control the amount of liquid to infiltrate, as well as suction, by the inverse rotation of the motor (M), blood from the patient's vein, to indicate that it is in the vein, as a pre-injection step.
  • the external control (20) can comprise the pedal (f) or a manually operated infiltrating device that includes push-buttons that enable the recoil of the plunger (2) of Figure 1 to be activated, in order to facilitate an initial blood aspiration, as well as the advance of said plunger (2) for the injection of the medicine ', this external control (20) being able to be linked to the rest of the electronic circuit by means of connecting cables, or, operated wirelessly, by means of additional circuits
  • the syringe sensor (27) is connected to determine the volume of medication allowed by said syringe (a), figure 1, depending on the outside diameter thereof, data that is processed by the microprocessor (31) to the correct dosage of the medicine, adjusting the speed of rotation of the stepper motor (M) and, as a consequence, the speed of advance of the piston (2) inside the cylinder (1), being the diameter of the piston (2) calibrated by means designed for this purpose including, in addition, this syringe sensor (27), a travel start sensor (14) and another piston travel end sensor (15) in the cylinder (1), those that send a signal to the microprocessor when the plunger (2) is at the end / start of said path.
  • the aforementioned sensors (14) and (15) are located inside the housing (d) and comprise conventional relays, being in a resting position, when they are "normal open” and so that, when a nut moves through the auger (S) reaches the end / start of the circuit, activates the relay and hits it, sending a low level signal to the adapter circuit (28), which produces the microprocessor management (31) necessary to indicate on the display (24) the end / start of the tour.
  • the syringe size sensor includes a three position wrench (for the three syringe sizes (a)), each position generates a "normal open", each position being connected to two relays. So that when the position is activated the relay is "stuck" generating a low-level signal, the three signals are connected to the terminals of the adapter circuit (28) that notify the micro in which position the key is. The latter thus activates the program stored in EPROM for the calculation of the dosage corresponding to that syringe size (a).
  • syringe sizes (a) can be standard, in which case the three positions indicated can correspond to 10, 20 and 60 cm 3 .
  • the microprocessor (31) contains the programming of a routine of elimination of the drip of the conduit (4) due to the residual pressure, also allowing this microprocessor (31) to determine the movement of a solenoid which pushes back to the plunger (2) of the syringe (a) and of the reversal of the motor rotation (M) step by step, the 100/200 type motor being high precision step-by-turn.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Manufacturing & Machinery (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

L'équipement comprend une chambre (a) comprenant à une extrémité au moins un piston (2) connecté à un moyen de commande (c) pouvant produire dans la chambre (a) un volume variable et, à l'extrémité opposée, ladite chambre (a) se termine par un ajutage tubulaire (3) connecté à une aiguille hypodermique (7) elle-même reliée à l'ajutage tubulaire (3) par l'intermédaire d'un conduit jetable (4) raccordé à une poignée (e) de forme anatomique, ladite chambre (a) étant connectée à des moyens d'actionnement (b) commandés par des moyens de commande à distance (f).
PCT/ES1993/000101 1992-12-24 1993-12-23 Equipement doseur et producteur d'une action d'aspiration-impulsion, applicable a la phlebologie et autres applications medicales WO1994014488A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
ARP323.999 1992-12-24
AR32399992 1992-12-24
ARP325.890 1993-09-02
AR32589093 1993-09-02

Publications (1)

Publication Number Publication Date
WO1994014488A1 true WO1994014488A1 (fr) 1994-07-07

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PCT/ES1993/000101 WO1994014488A1 (fr) 1992-12-24 1993-12-23 Equipement doseur et producteur d'une action d'aspiration-impulsion, applicable a la phlebologie et autres applications medicales

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6022337A (en) * 1997-09-04 2000-02-08 Herbst; Walter Dental anesthetic and delivery injection unit
WO2001045767A2 (fr) * 1999-12-22 2001-06-28 Gambro Lundia Ab Telecommande destinee a des appareils extracorporels de traitement du sang
ES2220163A1 (es) * 1999-08-19 2004-12-01 Alceu Meibach Rosa, Jr. Sistema y metodo de inyeccion de liquidos medicinales.

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1105820A (en) * 1964-11-12 1968-03-13 Ake Samuel Gidlund Apparatus for injecting dosages of contrast agent into the human body
US3472226A (en) * 1960-11-03 1969-10-14 Christian Haber Device for serial inoculations and for the execution of successive serological and bacteriological tests
US4306566A (en) * 1978-06-07 1981-12-22 Gesco International, Inc. Cholangiogram catheter
WO1989011883A1 (fr) * 1988-06-09 1989-12-14 Dell Orti Massimo Dispositif automatique d'aspiration et/ou d'injection pour des applications medicales
US5019037A (en) * 1989-07-06 1991-05-28 Alcon Laboratories, Inc. Pneumatic retinopexy injector

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3472226A (en) * 1960-11-03 1969-10-14 Christian Haber Device for serial inoculations and for the execution of successive serological and bacteriological tests
GB1105820A (en) * 1964-11-12 1968-03-13 Ake Samuel Gidlund Apparatus for injecting dosages of contrast agent into the human body
US4306566A (en) * 1978-06-07 1981-12-22 Gesco International, Inc. Cholangiogram catheter
WO1989011883A1 (fr) * 1988-06-09 1989-12-14 Dell Orti Massimo Dispositif automatique d'aspiration et/ou d'injection pour des applications medicales
US5019037A (en) * 1989-07-06 1991-05-28 Alcon Laboratories, Inc. Pneumatic retinopexy injector

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6022337A (en) * 1997-09-04 2000-02-08 Herbst; Walter Dental anesthetic and delivery injection unit
ES2220163A1 (es) * 1999-08-19 2004-12-01 Alceu Meibach Rosa, Jr. Sistema y metodo de inyeccion de liquidos medicinales.
WO2001045767A2 (fr) * 1999-12-22 2001-06-28 Gambro Lundia Ab Telecommande destinee a des appareils extracorporels de traitement du sang
WO2001045767A3 (fr) * 1999-12-22 2002-01-10 Gambro Lundia Ab Telecommande destinee a des appareils extracorporels de traitement du sang

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