UY37538A - Amidas aromáticas de ácidos carboxílicos - Google Patents
Amidas aromáticas de ácidos carboxílicosInfo
- Publication number
- UY37538A UY37538A UY0001037538A UY37538A UY37538A UY 37538 A UY37538 A UY 37538A UY 0001037538 A UY0001037538 A UY 0001037538A UY 37538 A UY37538 A UY 37538A UY 37538 A UY37538 A UY 37538A
- Authority
- UY
- Uruguay
- Prior art keywords
- carboxylic acids
- aromatic amides
- compounds
- aromatic
- prophylaxis
- Prior art date
Links
- 150000001735 carboxylic acids Chemical class 0.000 title abstract 2
- 150000008430 aromatic amides Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- -1 aromatic amide compounds Chemical class 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/58—Radicals substituted by nitrogen atoms
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
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- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
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- A61K31/415—1,2-Diazoles
- A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
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- A61K31/425—Thiazoles
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- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
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- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
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Abstract
La presente invención se refiere a compuestos de amidas aromáticas de ácidos carboxílicos de la fórmula general (I) como se describen y definen en el presente, a composiciones farmacéuticas y combinaciones que comprenden dichos compuestos, así como al uso de dichos compuestos en la elaboración de una composición farmacéutica para el tratamiento o profilaxis de una enfermedad como agente único o en combinación con otros ingredientes activos.
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ID=57609782
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UY0001037538A UY37538A (es) | 2016-12-23 | 2017-12-21 | Amidas aromáticas de ácidos carboxílicos |
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TW202317519A (zh) | 2021-07-05 | 2023-05-01 | 德商拜耳廠股份有限公司 | 2-(1-環丁基-1h-吡唑-4-基)-5-[({1-[2-氟-4-(三氟甲基)-苯基]環丙基}羰基)胺基]苯甲酸之膽鹼鹽 |
WO2023016518A1 (zh) | 2021-08-11 | 2023-02-16 | 四川海思科制药有限公司 | 一种杂环衍生物及其组合物和药学上的应用 |
TW202330471A (zh) * | 2021-09-30 | 2023-08-01 | 日商住友製藥股份有限公司 | 環丙醯胺衍生物 |
CN114591338B (zh) * | 2022-03-31 | 2023-05-09 | 苏州欧康维视生物科技有限公司 | 一种Syk和VEGFR2双靶点抑制剂的制备方法及其用途 |
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DE19624155A1 (de) * | 1996-06-18 | 1998-01-08 | Hoechst Ag | Substituierte Benzoesäurederivate, Verfahren zu ihrer Herstellung und die Anwendung der Verbindungen zur Behandlung von Krankheiten |
GB0102687D0 (en) | 2001-02-02 | 2001-03-21 | Pharmacia & Upjohn Spa | Oxazolyl-pyrazole derivatives active as kinase inhibitors,process for their preparation and pharmaceutical compositions comprising them |
ATE316954T1 (de) | 2002-02-08 | 2006-02-15 | Merck & Co Inc | N-biphenylmethylaminocycloalkancarboxamid- derivative |
US20070124389A1 (en) | 2005-11-28 | 2007-05-31 | Lucent Technologies Inc. | Anti-spam application storage system |
EP2016065B1 (en) | 2005-12-28 | 2012-09-19 | Vertex Pharmaceuticals Incorporated | 1-(benzo[d][1,3]dioxol-5-yl)-n-(phenyl)cyclopropane-carboxamide derivatives and related compounds as modulators of atp-binding cassette transporters for the treatment of cystic fibrosis |
AR068509A1 (es) | 2007-09-19 | 2009-11-18 | Jerini Ag | Antagosnistas del receptor de bradiquinina b1 |
TW201217312A (en) * | 2010-09-22 | 2012-05-01 | Gruenenthal Gmbh | Substituted benzamide compounds |
HUP1000598A2 (en) | 2010-11-05 | 2012-09-28 | Richter Gedeon Nyrt | Indole derivatives |
US9062013B2 (en) * | 2011-02-02 | 2015-06-23 | Bionomics Limited | Positive allosteric modulators of the α7 nicotinic acetylcholine receptor and uses thereof |
WO2012112363A1 (en) | 2011-02-14 | 2012-08-23 | Merck Sharp & Dohme Corp. | Cathepsin cysteine protease inhibitors |
WO2012112567A1 (en) | 2011-02-15 | 2012-08-23 | Georgetown University | Small molecule inhibitors of agbl2 |
BR112014031360B1 (pt) * | 2012-06-15 | 2022-04-12 | Taisho Pharmaceutical Co., Ltd | Composto, composição farmacêutica e medicamento terapêutico ou preventivo |
HRP20231614T1 (hr) | 2016-03-28 | 2024-03-15 | Incyte Corporation | Spojevi pirolotriazina kao tam inhibitori |
SI3558390T1 (sl) | 2016-12-23 | 2025-01-31 | Heidelberg Pharma Research Gmbh | Konjugati amanitina in protitelesa |
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